Patents by Inventor Fiona A. Harding

Fiona A. Harding has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins
    Patent number: 6596525
    Abstract: The present invention relates to a novel improved protein mutant which produces low allergenic response in humans compared to the parent of that mutant. Specifically, the present invention comprises neutralizing or reducing the ability of T-cells to recognize epitopes and thus prevent sensitization of an individual to the protein.
    Type: Grant
    Filed: February 23, 1999
    Date of Patent: July 22, 2003
    Assignee: Genencor International, Inc.
    Inventors: David A. Estell, Fiona A. Harding
  • Proteins producing an altered immunogenic response and methods of making and using the same
    Publication number: 20030118605
    Abstract: The present invention relates to novel protein variants that exhibit reduced allergenicity when compared to the parental proteins. Also included are DNA molecules that encode the novel variants, host cells comprising the DNA and methods of making proteins less allergenic.
    Type: Application
    Filed: March 22, 2002
    Publication date: June 26, 2003
    Inventors: David A. Estell, Grant C. Ganshaw, Fiona A. Harding, Edmund A. Larenas, Ayrookaran J. Poulose, Elizabeth E. Sikorski, Elliott P. Russell
  • Transgenic mammal capable of facilitating production of donor-specific functional immunity
    Publication number: 20030028911
    Abstract: This invention provides for transgenic non-human mammalian models of human disease, methods of making such models as well as methods of using such models to assess efficacy of therapeutic and prophylaxis treatments, to assess the antigenic potential of compounds, and other uses.
    Type: Application
    Filed: August 23, 2001
    Publication date: February 6, 2003
    Inventors: Manley Huang, Fiona A. Harding
  • Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins
    Patent number: 6218165
    Abstract: The present invention relates to a novel improved protein mutant which produces low allergenic response in humans compared to the parent of that mutant. Specifically, the present invention comprises neutralizing or reducing the ability of T-cells to recognize epitopes and thus prevent sensitization of an individual to the protein.
    Type: Grant
    Filed: February 23, 1999
    Date of Patent: April 17, 2001
    Assignee: Genencor International, Inc.
    Inventors: David A. Estell, Fiona A. Harding