Patents by Inventor Foe S. Tjoeng

Foe S. Tjoeng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyridyl peptide mimetic compounds which are useful platelet-aggregation inhibitors
    Patent number: 5091396
    Abstract: Novel peptide mimetic compounds are provided which have useful activity as inhibitors of platelet aggregation. These compounds have the chemical structure ##STR1## wherein x=4 to 8,y=0 to 4,W=CH.sub.2 --CH.sub.2 or C.dbd.CH,Z=H, COOH, CONH.sub.2, CH.sub.2 OH, CO.sub.2 R, CH.sub.2 OR or C.sub.1-6 alkyl,R=C.sub.1-6 alkyl,Ar=a nitrogen-containing heterocyclic group, andAsp=aspartic acid residue.
    Type: Grant
    Filed: January 7, 1991
    Date of Patent: February 25, 1992
    Assignees: Monsanto Co., G. D. Searle & Co.
    Inventors: Foe S. Tjoeng, Steven P. Adams, Robert B. Garland, Masateru Miyano
  • Novel platelet-aggregation inhibitor
    Patent number: 5053393
    Abstract: N-[8-[(Aminoiminomethyl)amino]-1-oxooctyl]-N-L-.alpha.-aspartyl-L-phenylani ne is disclosed as a highly potent inhibitor of platelet aggregation.
    Type: Grant
    Filed: June 20, 1990
    Date of Patent: October 1, 1991
    Assignees: Monsanto Company, G. D. Searle & Co.
    Inventors: Foe S. Tjoeng, Larry P. Feigen, Steven P. Adams
  • Indolyl platelet-aggregation inhibitors
    Patent number: 5037808
    Abstract: Novel peptide mimetic compounds are provided which have useful activity as inhibitors of platelet aggregation. These compounds have the chemical structure ##STR1## wherein x=4 to 8,y=0 to 4,W=CH.sub.2 --CH.sub.2 or CH.dbd.CH,Z=H, COOH, CONH.sub.2, CH.sub.2 OH, CO.sub.2 R, CH.sub.2 OR or C.sub.1-6 alkyl,R=C.sub.1-6 alkyl,Ar=a nitrogen-containing heterocyclic group, andAsp=aspartic acid residue.
    Type: Grant
    Filed: April 23, 1990
    Date of Patent: August 6, 1991
    Assignees: Monsanto Co., G. D. Searle & Co.
    Inventors: Foe S. Tjoeng, Steven P. Adams, Robert B. Garland, Masateru Miyano
  • Thienyl peptide mimetic compounds which are useful in inhibiting platelet aggregation
    Patent number: 4992463
    Abstract: Novel peptide mimetic compounds are provided which have useful activity as inhibitors of platelet aggregation. These compounds have the chemical structure ##STR1## wherein x=6 to 10,y=0 to 4,Z=H, COOH, CONH.sub.2 or C.sub.1-6 alkyl,Ar=phenyl, biphenyl or napthyl, each substituted with 1 to 3 methoxy groups, or an unsubstituted phenyl, biphenyl, napthyl, pyridyl or thienyl group, andAsp=aspartic acid residue.
    Type: Grant
    Filed: August 18, 1989
    Date of Patent: February 12, 1991
    Assignee: Monsanto Company
    Inventors: Foe S. Tjoeng, Steven P. Adams
  • Novel platelet-aggregation inhibitors
    Patent number: 4879313
    Abstract: Novel peptide mimetic compounds are provided which have useful activity as inhibitors of platelet aggregation. These compounds have the chemical structure ##STR1## wherein x=6 to 10,y=0 to 4,Z=H, COOH, CONH.sub.2 or C.sub.1-6 alkyl,Ar=phenyl, biphenyl or napthyl, each substituted with 1 to 3 methoxy groups, or an unsubstituted phenyl, biphenyl, napthyl, pyridyl or thienyl group, andAsp=aspartic acid residue.
    Type: Grant
    Filed: July 20, 1988
    Date of Patent: November 7, 1989
    Assignee: Mosanto Company
    Inventors: Foe S. Tjoeng, Steven P. Adams
  • Synthetic airial peptides
    Patent number: 4716147
    Abstract: Novel synthetic atrial peptides are provided with enhanced natriuretic properties by substituting one or two arginine residues for the N-terminal ser-ser in atriopeptins I, II and III and their physiologically acceptable salts, esters and amides.
    Type: Grant
    Filed: March 27, 1986
    Date of Patent: December 29, 1987
    Assignee: Monsanto Company
    Inventors: Foe S. Tjoeng, Kam F. Fok, Steven P. Adams