Patents by Inventor Francis X. Smith

Francis X. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OPHTHALMIC AND CONTACT LENS SOLUTIONS USING CHOLINE
    Publication number: 20140163113
    Abstract: The present invention relates to a lens care solution having 0.001 to about 5 weight percent of a low molecular weight amine of the general formula: where R1, R2, R3 and R4 are —H or low molecular weight radicals, and R5 is a low molecular weight radical, or salt thereof; an effective amount of a tonicity agent; and the balance water.
    Type: Application
    Filed: February 14, 2014
    Publication date: June 12, 2014
    Applicant: FXS Ventures, LLC
    Inventor: Francis X. Smith
  • Ophthalmic and contact lens solutions using choline
    Patent number: 8691876
    Abstract: The present invention relates to a lens care solution having 0.001 to about 5 weight percent of a low molecular weight amine of the general formula: where R1, R2, R3 and R4 are —H or low molecular weight radicals, and R5 is a low molecular weight radical, or salt thereof; an effective amount of a tonicity agent; and the balance water.
    Type: Grant
    Filed: April 25, 2013
    Date of Patent: April 8, 2014
    Assignee: FXS Ventures, LLC
    Inventor: Francis X. Smith
  • L-HISTIDINE IN OPHTHALMIC SOLUTIONS
    Publication number: 20140093472
    Abstract: The invention relates to an aqueous ophthalmic solution comprising 0.00001 to about 10.0 percent by weight L-histidine, 0.0001 to 3.0 percent by weight hydrogen peroxide, and optionally 0.1 to 500 parts per million of a preservative that provides superior preservative efficacy especially as against fungal microbes. These solutions may be employed in various ways including cleaning contact lenses, rinsing lenses while in the eye, storing lenses and in delivering active pharmaceutical agents to the eye.
    Type: Application
    Filed: December 6, 2013
    Publication date: April 3, 2014
    Applicant: FXS Ventures, LLC
    Inventor: Francis X. Smith
  • Ophthalmic and contact lens solutions using low molecular weight amines
    Patent number: 8557868
    Abstract: The present invention relates to a lens care solution comprising: 0.001 to about 5 weight percent of a low molecular weight amine of the general formula: Where R1, R2, R3 and R4 are —H or low molecular weight radicals, and R5 is a low molecular weight radical, or salt thereof; an effective amount of tonicity agent; and the balance water.
    Type: Grant
    Filed: November 14, 2002
    Date of Patent: October 15, 2013
    Assignee: FXS Ventures, LLC
    Inventor: Francis X. Smith
  • OPHTHALMIC AND CONTACT LENS SOLUTIONS USING CHOLINE
    Publication number: 20130237606
    Abstract: The present invention relates to a lens care solution having 0.001 to about 5 weight percent of a low molecular weight amine of the general formula: where R1, R2, R3 and R4 are —H or low molecular weight radicals, and R5 is a low molecular weight radical, or salt thereof; an effective amount of a tonicity agent; and the balance water.
    Type: Application
    Filed: April 25, 2013
    Publication date: September 12, 2013
    Applicant: FXS Ventures, LLC
    Inventor: Francis X. Smith
  • OPHTHALMIC AND CONTACT LENS SOLUTIONS USING BIS-TRIS
    Publication number: 20130233740
    Abstract: The present invention relates to a lens care solution having 0.001 to about 5 weight percent of a low molecular weight amine of the general formula: where R1, R2, R3 and R4 are —H or low molecular weight radicals, and R5 is a low molecular weight radical, or salt thereof; an effective amount of a tonicity agent; and the balance water.
    Type: Application
    Filed: April 25, 2013
    Publication date: September 12, 2013
    Applicant: FXS Ventures, LLC
    Inventor: Francis X. Smith
  • OPHTHALMIC AND CONTACT LENS SOLUTIONS USING CARNITINE
    Publication number: 20130233734
    Abstract: The present invention relates to a lens care solution having 0.001 to about 5 weight percent of a low molecular weight amine of the general formula: where R1, R2, R3 and R4 are —H or low molecular weight radicals, and R5 is a low molecular weight radical, or salt thereof; an effective amount of a tonicity agent; and the balance water.
    Type: Application
    Filed: April 25, 2013
    Publication date: September 12, 2013
    Applicant: FXS Ventures, LLC
    Inventor: Francis X. Smith
  • OPHTHALMIC AND CONTACT LENS SOLUTIONS USING AN ALIPHATIC AMINO ALCOHOL
    Publication number: 20130233201
    Abstract: The present invention relates to a lens care solution having 0.001 to about 5 weight percent of a low molecular weight amine of the general formula: where R1, R2, R3 and R4 are —H or low molecular weight radicals, and R5 is a low molecular weight radical, or salt thereof; an effective amount of a tonicity agent; and the balance water.
    Type: Application
    Filed: April 25, 2013
    Publication date: September 12, 2013
    Applicant: FXS Ventures, LLC
    Inventor: Francis X. Smith
  • OPHTHALMIC AND CONTACT LENS SOLUTIONS USING TRICINE
    Publication number: 20130228477
    Abstract: The present invention relates to a lens care solution having 0.001 to about 5 weight percent of a low molecular weight amine of the general formula: where R1, R2, R3 and R4 are —H or low molecular weight radicals, and R5 is a low molecular weight radical, or salt thereof; an effective amount of a tonicity agent; and the balance water.
    Type: Application
    Filed: April 25, 2013
    Publication date: September 5, 2013
    Applicant: FXS Ventures, LLC
    Inventor: Francis X. Smith
  • Ophthalmic and contact lens solution
    Patent number: 8247461
    Abstract: An ophthalmic solution comprising a polyethoxylated glyceride in the range of 0.001 to about 10 percent by weight and a buffer agent. These solutions impart surprising comfort and wearability to contact lenses. At the same time the solutions provide good preservative capacity and do not increase protein deposit.
    Type: Grant
    Filed: January 26, 2010
    Date of Patent: August 21, 2012
    Inventors: Francis X. Smith, John Randall Tracey
  • OPHTHALMIC AND CONTACT LENS SOLUTION
    Publication number: 20120083534
    Abstract: An ophthalmic solution comprising a polyethoxylated glyceride in the range of 0.001 to about 10 percent by weight and a buffer agent. These solutions impart surprising comfort and wearability to contact lenses. At the same time the solutions provide good preservative capacity and do not increase protein deposit.
    Type: Application
    Filed: December 15, 2011
    Publication date: April 5, 2012
    Inventors: Francis X. Smith, John Randall Tracey
  • Ophthalmic and Contact Lens Solutions Using Low Molecular Weight Amines
    Publication number: 20120017806
    Abstract: The present invention relates to a lens care solution comprising: 0.001 to about 5 weight percent of a low molecular weight amine of the general formula: Where R1, R2, R3 and R4 are —H or low molecular weight radicals, and R5 is a low molecular weight radical, or salt thereof; an effective amount of tonicity agent; and the balance water.
    Type: Application
    Filed: August 1, 2011
    Publication date: January 26, 2012
    Inventor: Francis X. Smith
  • OPHTHALMIC AND CONTACT LENS SOLUTIONS CONTAINING PEPTIDES AS PRESERVATIVE
    Publication number: 20110212885
    Abstract: A method and a contact lens solution comprising 0.001 to 10 weight percent or a preservative enhancer chosen from the group consisting of: SEQ ID NO.1 and SEQ ID NO. 2; and at least 0.0001 weight percent of a preservative agent, and where the concentration of chloride in said solution is less than 0.2 percent by weight.
    Type: Application
    Filed: March 1, 2011
    Publication date: September 1, 2011
    Inventors: Francis X. Smith, Kathryn S. Crawford
  • Ophthalmic and contact lens solutions containing peptides as preservative
    Patent number: 7939501
    Abstract: A contact lens solution comprising 0.001 to 10 weight percent or a preservative enhancer chosen from the group consisting of: D4E1, D2A21, and P-113; and at least 0.0001 weight percent of a preservative, and where the concentration of chloride in said solution is less than 0.2 percent by weight.
    Type: Grant
    Filed: April 15, 2004
    Date of Patent: May 10, 2011
    Inventors: Francis X. Smith, Kathryn S. Crawford
  • OPHTHALMIC AND CONTACT LENS SOLUTION
    Publication number: 20100122918
    Abstract: An ophthalmic solution comprising a polyethoxylated glyceride in the range of 0.001 to about 10 percent by weight and a buffer agent. These solutions impart surprising comfort and wearability to contact lenses. At the same time the solutions provide good preservative capacity and do not increase protein deposit.
    Type: Application
    Filed: January 26, 2010
    Publication date: May 20, 2010
    Inventors: Francis X. Smith, John Randall Tracey
  • Method for rendering a contact lens wettable
    Patent number: 7678836
    Abstract: An ophthalmic solution comprising a polyethoxylated glyceride in the range of 0.001 to about 10 percent by weight and a buffer agent. These solutions impart surprising comfort and wearability to contact lenses. At the same time the solutions provide good preservative capacity and do not increase protein deposit.
    Type: Grant
    Filed: May 10, 2004
    Date of Patent: March 16, 2010
    Assignee: FXS Ventures, LLC
    Inventors: Francis X Smith, John Randall Tracey
  • Ophthalmic formulations of Amyloid-beta contrast agent and methods of use thereof
    Publication number: 20090041666
    Abstract: The invention provides ophthalmic formulations of Amyloid-? contrast agents. Also provided are methods of using such formulations in the diagnosis of Alzheimer's Disease or a predisposition thereto as well as methods for the prognosis of Alzheimer's Disease.
    Type: Application
    Filed: May 21, 2008
    Publication date: February 12, 2009
    Inventors: Lee E. Goldstein, Evan A. Sherr, Paul D. Hartung, Francis X. Smith, Kevin R. Sullivan
  • Ophthalmic and Contact Lens Solutions Containing Peptides as Preservative
    Publication number: 20080167246
    Abstract: A contact lens solution comprising 0.001 to 10 weight percent or a preservative enhancer chosen from the group consisting of: D4E1, D2A21, and P-113; and at least 0.0001 weight percent of a preservative, and where the concentration of chloride in said solution is less than 0.2 percent by weight.
    Type: Application
    Filed: April 15, 2004
    Publication date: July 10, 2008
    Inventors: Francis X. Smith, Kathryn S. Crawford
  • Ophthalmic and contact lens solutions comprising imidazole
    Patent number: 7067547
    Abstract: The present invention relates to contact lens solutions employing imidazole as an additive. Lenses treated with these solutions have improved resistance to protein and other polymeric depositions. The addition of imidazole to the solutions decreases the denaturalization of proteins during the cleaning cycles, and coats treated lenses to decrease the number of active binding sites.
    Type: Grant
    Filed: November 4, 2000
    Date of Patent: June 27, 2006
    Assignee: FXS Ventures, LLC
    Inventor: Francis X. Smith
  • Ophthalmic and contact lens solutions using low molecular weight amines
    Publication number: 20030190258
    Abstract: The present invention relates to a lens care solution comprising:
    Type: Application
    Filed: November 14, 2002
    Publication date: October 9, 2003
    Inventor: Francis X. Smith