Patents by Inventor Franck Zal

Franck Zal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of a Haemoglobin for the Preparation of Dressings and Resulting Dressings
    Publication number: 20100278887
    Abstract: The invention relates to the use of a haemoglobin for the preparation of dressings and to the resulting dressings.
    Type: Application
    Filed: June 10, 2008
    Publication date: November 4, 2010
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS, HEMARINA SA, UNIVERSITE PIERRE ET MARIE CURIE
    Inventors: Franck Zal, Morgane Rousselot
  • Use Of A High Molecular Weight Extracellular Hemoglobin For The Manufacture Of A Medicament For Treating And/Or Preventing Diseases By Inhibition Of Calcium
    Publication number: 20100234275
    Abstract: The present invent ion relates to the use of a high molecular weight extracellular hemoglobin for the manufacture of a medicament for treating and/or preventing diseases by inhibition of calcium. Advantageously, the extracellular hemoglobin is obtained from Annelids. In particular, the invention concerns the use of a high molecular weight extracellular hemoglobin for the manufacture of a medicament for treating and/or preventing cardiovascular diseases, such as hypertension, angina such as angina pectoris, Raynaud's disease, arteriopathy, tachycardia, vasospasm, ischemia, myocardial infarct ion, congestive heart failure, arrhythmia or cerebrovacular accident.
    Type: Application
    Filed: January 23, 2007
    Publication date: September 16, 2010
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Franck Zal, Morgane Rousselot
  • Use of a Globin, a Globin Protomer or an Extracellular Hemoglobin for the Preservation of Organs, Tissues, Organ and Tissue Cells and Cell Cultures
    Publication number: 20100209902
    Abstract: The invention relates to the use of at least one globin and/or at least one globin protomer and/or at least one naturally extracellular native hemoglobin for the preservation of organs, tissues, organ and tissue cells and cell cultures.
    Type: Application
    Filed: July 25, 2008
    Publication date: August 19, 2010
    Applicants: HEMARINA SA, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6)
    Inventors: Franck Zal, Morgane Rousselot, Delphine Dutheil
  • Method for the dissociation of the extracellular haemoglobin molecule of and the characterization of the protein chains forming the molecule and the nucleotide sequences coding for said protein chains
    Patent number: 7776526
    Abstract: Method of dissociating the extracellular haemoglobin molecule of annelids, e.g. Arenicola marina, which can be used to obtain the protein chains forming the molecule. The method includes a step of bringing an extracellular haemoglobin sample from annelids, e.g. Arenicola marina, into contact with at least one dissociating agent, e.g. a mixture containing dithiothreitol (DTT) or tris(2-carboxyethyl)phosphine (TCEP) hydrochloride or beta-mercaptoethanol and a dissociation buffer for a sufficient length of time in order to separate the protein chains from one another.
    Type: Grant
    Filed: October 13, 2004
    Date of Patent: August 17, 2010
    Assignees: Centre National de la Recherche Scientifique, Universite Pierre et Marie Curie
    Inventors: Franck Zal, Christine Chabasse, Morgane Rousselot, Xavier Bailly
  • USE OF A HIGH MOLECULAR WEIGHT EXTRACELLULAR HAEMOGLOBIN AS A BLOOD SUBSTITUTE
    Publication number: 20080305178
    Abstract: A blood substitute, of an extracellular haemoglobin having a molecular weight of approximately 3 to approximately 4 million daltons, comp sing chains of polymerised globins, containing free cysteines capable of binding to NO and/or SNO groups, and having a P50 of approximately 6 to approximately 7 mm Hg, and methods using the blood substitute.
    Type: Application
    Filed: April 28, 2008
    Publication date: December 11, 2008
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Franck ZAL, Andre TOULMOND, Francois LALLIER
  • Use a high-molecular-weight extracellular haemoglobin as a blood substitute
    Publication number: 20030181358
    Abstract: The invention concerns the use as blood substitute of a high-molecular-weight extracellular haemoglobin of about 3 to about 4 million daltons, comprising polymerised globin chains, containing free cysteines capable of binding to NO and/or SNO groups and whereof the P50 is about 6 to 7 mm Hg at 37° C.
    Type: Application
    Filed: May 20, 2003
    Publication date: September 25, 2003
    Inventors: Franck Zal, Andre Toulmond, Francois Lallier