Patents by Inventor Gerald E. Loeb
Gerald E. Loeb has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20100139418Abstract: Tactile sensors are disclosed that mimic the human fingertip and its touch receptors. The mechanical components are similar to a fingertip, with a rigid core surrounded by a weakly conductive fluid contained within an elastomeric skin. The deformable properties of the finger pad can be used as part of a transduction process. Multiple electrodes can be mounted on the surface of the rigid core and connected to impedance measuring circuitry within the core. External forces deform the fluid path around the electrodes, resulting in a distributed pattern of impedance changes containing information about those forces and the objects that applied them. Strategies are described for extracting features related to the mechanical inputs and using this information for reflexive grip control. Controlling grip force in a prosthetic having sensory feedback information is described. Pressure transducers can provide sensory feedback by measuring micro-vibrations due to sliding friction.Type: ApplicationFiled: April 2, 2009Publication date: June 10, 2010Applicant: UNIVERSITY OF SOUTHERN CALIFORNIAInventors: Gerald E. Loeb, Jeremy Fishel, Nicholas Wettels, Veronica J. Santos, Raymond Peck
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Patent number: 7658119Abstract: Disclosed is a tactile sensory system consisting of set of sensors that work by measuring impedance among plurality of electrodes. The electrodes are deployed on a substantially rigid structure that is protected form the direct contact with external objects by overlying deformable structures. These mechanical structures have similarities to the biological relationships among the distal phalanx, overlying finger pulp and covering skin and nail. Signal information is extracted form these sensors that is related to canonical physical representations used to describe stimuli to be sensed.Type: GrantFiled: March 28, 2007Date of Patent: February 9, 2010Assignee: University of Southern CaliforniaInventors: Gerald E. Loeb, Roland Johansson
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Publication number: 20090272201Abstract: Tactile sensors are disclosed that mimic the human fingertip and its touch receptors. The mechanical components are similar to a fingertip, with a rigid core surrounded by a weakly conductive fluid contained within an elastomeric skin. The deformable properties of the finger pad can be used as part of a transduction process. Multiple electrodes can be mounted on the surface of the rigid core and connected to impedance measuring circuitry within the core. External forces deform the fluid path around the electrodes, resulting in a distributed pattern of impedance changes containing information about those forces and the objects that applied them. Strategies are described for extracting features related to the mechanical inputs and using this information for reflexive grip control. Controlling grip force in a prosthetic having sensory feedback information is described. Techniques are described for enhancing the useful force range for impedance sensors by internally texturing the elastomeric skin.Type: ApplicationFiled: April 2, 2009Publication date: November 5, 2009Applicant: UNIVERSITY OF SOUTHERN CALIFORNIAInventors: Gerald E. Loeb, Nicholas Wettels, Jeremy Fishel, Chia Hsien (Gary) Lin, Veronica J. Santos, Raymond Peck
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Publication number: 20090240302Abstract: An implantable pulse generator includes a current steering capability that allows a clinician or patient to quickly determine a desired electrode stimulation pattern, including which electrodes of a group of electrodes within an electrode array should receive a stimulation current, including the amplitude, width and pulse repetition rate of such current. Movement of the selected group of electrodes is facilitated through the use of remotely generated directional signals, generated by a pointing device, such as a joystick. As movement of the selected group of electrodes occurs, current redistribution amongst the various electrode contacts takes place. The redistribution of stimulus amplitudes utilizes re-normalization of amplitudes so that the perceptual level remains fairly constant. This prevents the resulting paresthesia from falling below the perceptual threshold or above the comfort threshold.Type: ApplicationFiled: June 2, 2009Publication date: September 24, 2009Applicant: BOSTON SCIENTIFIC NEUROMODULATION CORPORATIONInventors: Carla Mann Woods, David K.L. Peterson, Paul M. Meadows, Gerald E. Loeb
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Patent number: 7593776Abstract: A novel system and method for restoring functional movement of a paralyzed limb(s) or a prosthetic device. Stimulating one or more muscles of a patient using an implanted neuromuscular implants and sensing the response of the stimulated muscle by the implants, wherein the sensing the response is not limited to data related to patient's movement intention, the posture, muscle extension, M-Wave and EMG. A communication and control protocol to operate the system safely and efficiently, use of forward and reverse telemetry channels having a limited bandwidth capacity, and minimizing the adverse consequences caused by errors in data transmission and intermittent loss of power to the implants. Adjusting stimulation rates and phases of the stimulator in order to achieve an efficient control of muscle force while minimizing fatigue and therefore providing for smooth movements and dynamic increase of the strength in patient's muscle contraction.Type: GrantFiled: July 3, 2007Date of Patent: September 22, 2009Assignee: University of Southern CaliforniaInventors: Gerald E. Loeb, Jack Weissberg, Nuria Rodriguez
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Patent number: 7555347Abstract: Devices and methods for locating a target site for the electrical stimulation of muscles are disclosed. The intensity of a search stimulus is varied continuously near the threshold to evoke an M-wave recorded by EMG electrodes. A feedback signal allows the clinician to judge when the threshold is sufficiently low to warrant the implantation of the stimulation electrodes at that site.Type: GrantFiled: April 11, 2005Date of Patent: June 30, 2009Assignee: Alfred E. Mann Institute for Biomedical Engineering at the University of Southern CaliforniaInventor: Gerald E. Loeb
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Patent number: 7555346Abstract: An implantable pulse generator includes a current steering capability that allows a clinician or patient to quickly determine a desired electrode stimulation pattern, including which electrodes of a group of electrodes within an electrode array should receive a stimulation current, including the amplitude, width and pulse repetition rate of such current. Movement of the selected group of electrodes is facilitated through the use of remotely generated directional signals, generated by a pointing device, such as a joystick. As movement of the selected group of electrodes occurs, current redistribution amongst the various electrode contacts takes place. The redistribution of stimulus amplitudes utilizes re-normalization of amplitudes so that the perceptual level remains fairly constant. This prevents the resulting paresthesia from falling below the perceptual threshold or above the comfort threshold.Type: GrantFiled: June 21, 2005Date of Patent: June 30, 2009Assignee: Boston Scientific Neuromodulation CorporationInventors: Carla Mann Woods, David K. L Peterson, Paul M. Meadows, Gerald E. Loeb
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Publication number: 20090133508Abstract: Disclosed is a robust tactile sensor array that mimics the human fingertip and its touch receptors. The mechanical components are similar to a fingertip, with a rigid core surrounded by a weakly conductive fluid contained within an elastomeric skin. It uses the deformable properties of the finger pad as part of the transduction process. Multiple electrodes are mounted on the surface of the rigid core and connected to impedance measuring circuitry within the core. External forces deform the fluid path around the electrodes, resulting in a distributed pattern of impedance changes containing information about those forces and the objects that applied them. Strategies for extracting features related to the mechanical inputs and using this information for reflexive grip control.Type: ApplicationFiled: May 16, 2008Publication date: May 28, 2009Applicant: UNIVERSITY OF SOUTHERN CALIFORNIAInventors: Roland S. Johansson, Gerald E. Loeb, Nicholas Wettels, Djordje Popovic, Veronica J. Santos
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Publication number: 20080221637Abstract: An implantable pulse generator includes a current steering capability that allows a clinician or patient to quickly determine a desired electrode stimulation pattern, including which electrodes of a group of electrodes within an electrode array should receive a stimulation current, including the amplitude, width and pulse repetition rate of such current. Movement of the selected group of electrodes is facilitated through the use of remotely generated directional signals, generated by a pointing device, such as a joystick. As movement of the selected group of electrodes occurs, current redistribution amongst the various electrode contacts takes place. The redistribution of stimulus amplitudes utilizes re-normalization of amplitudes so that the perceptual level remains fairly constant. This prevents the resulting paresthesia from falling below the perceptual threshold or above the comfort threshold.Type: ApplicationFiled: May 13, 2008Publication date: September 11, 2008Applicant: BOSTON SCIENTIFIC NEUROMODULATION CORPORATIONInventors: Carla Mann Woods, David K.L. Peterson, Paul M. Meadows, Gerald E. Loeb
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Publication number: 20080215119Abstract: An implantable pulse generator includes a current steering capability that allows a clinician or patient to quickly determine a desired electrode stimulation pattern, including which electrodes of a group of electrodes within an electrode array should receive a stimulation current, including the amplitude, width and pulse repetition rate of such current. Movement of the selected group of electrodes is facilitated through the use of remotely generated directional signals, generated by a pointing device, such as a joystick. As movement of the selected group of electrodes occurs, current redistribution amongst the various electrode contacts takes place. The redistribution of stimulus amplitudes utilizes re-normalization of amplitudes so that the perceptual level remains fairly constant. This prevents the resulting paresthesia from falling below the perceptual threshold or above the comfort threshold.Type: ApplicationFiled: May 13, 2008Publication date: September 4, 2008Applicant: BOSTON SCIENTIFIC NEUROMODULATION CORPORATIONInventors: Carla Mann Woods, David K. L. Peterson, Paul M. Meadows, Gerald E. Loeb
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Publication number: 20080140154Abstract: A novel system and method for restoring functional movement of a paralyzed limb(s) or a prosthetic device. Stimulating one or more muscles of a patient using an implanted neuromuscular implants and sensing the response of the stimulated muscle by the implants, wherein the sensing the response is not limited to data related to patient's movement intention, the posture, muscle extension, M-Wave and EMG. A communication and control protocol to operate the system safely and efficiently, use of forward and reverse telemetry channels having a limited bandwidth capacity, and minimizing the adverse consequences caused by errors in data transmission and intermittent loss of power to the implants. Adjusting stimulation rates and phases of the stimulator in order to achieve an efficient control of muscle force while minimizing fatigue and therefore providing for smooth movements and dynamic increase of the strength in patient's muscle contraction.Type: ApplicationFiled: July 3, 2007Publication date: June 12, 2008Inventors: Gerald E. Loeb, Jack Weissberg, Nuria Rodriguez
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Patent number: 7277749Abstract: Many individuals generate excessively loud snoring during their sleep, often to the point where others cannot tolerate sleeping in the same room with them. Most cases of snoring are caused by excessive bulk and flaccidity of soft tissues of the palate and uvula that vibrate as air flows past them. These palate and uvula contain muscles whose contractions can stiffen and displace the soft tissues so that they do not vibrate. The invention provides electrical stimulation that causes the oropharyngeal muscles to contract during sleep using one or more microstimulators injected into or near these muscles or the nerves which innervate them. The invention also provides methods of determining the anatomical structures implicated in snoring and testing such locations for effective placement and stimulation of muscle contraction to decrease the frequency or magnitude of snoring.Type: GrantFiled: January 15, 2004Date of Patent: October 2, 2007Assignee: Alfred E. Mann Institute for Biomedical Engineering at the University of Southern CaliforniaInventors: David C. Gordon, Gerald E. Loeb
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Patent number: 7096053Abstract: A biosensing device for detecting biological analytes, and methods of use and manufacture, are disclosed. The device includes a biosensing element that can remain implanted for extended periods of time. The biosensing element is connected to an optical fiber terminating outside of the body. The optical fiber is also connected to an information analyzer. The information analyzer directs light through the optical fiber into the biosensing element. The light excites fluorophores, created by a chemical reaction between analytes and biosensing material within the biosensing element. Emitted fluorescent light is redirected through the optical fiber to the information analyzer. Optical gratings within the filtering member of the information analyzer selectively deflect fluorescent emissions into a cladding layer.Type: GrantFiled: October 2, 2002Date of Patent: August 22, 2006Assignee: Alfred E. Mann Institute for Biomedical Engineering at the University of Southern CaliforniaInventors: Gerald E. Loeb, Thomas George
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Patent number: 6941171Abstract: A method and system for treatment of incontinence, urgency, frequency, and/or pelvic pain includes implantation of electrodes on a lead or the discharge portion of a catheter adjacent the perineal nerve(s) or tissue(s) to be stimulated. Stimulation pulses, either electrical or drug infusion pulses, are supplied by a stimulator implanted remotely, and through the lead or catheter, which is tunneled subcutaneously between the stimulator and stimulation site. For instance, the system and method reduce or eliminate the incidence of unintentional episodes of bladder emptying by stimulating nerve pathways that diminish involuntary bladder contractions, improve closure of the bladder outlet, and/or improve the long-term health of the urinary system by increasing bladder capacity and period between emptying.Type: GrantFiled: August 16, 2001Date of Patent: September 6, 2005Assignee: Advanced Bionics CorporationInventors: Carla M. Mann, Todd K. Whitehurst, James P. McGivern, Gerald E. Loeb, Frances J. R. Richmond
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Patent number: 6937904Abstract: Recovery from peripheral nerve and nerve plexus injuries is usually slow and incomplete because the regenerating motor axons often head erroneously toward sensory receptors rather than muscle fibers and because the target muscles atrophy while waiting for the slow process of reinnervation. Research has suggested that electrical stimulation with different waveforms and temporal patterns at different times during the regeneration process might improve the clinical outcome through various mechanisms, but a practical means to deliver such stimulation has been lacking. This invention teaches the use of miniature electrical stimulators that can be implanted alongside the injured nerve(s) at the time of surgical repair and that can be powered and controlled by transmission of radiofrequency energy from outside the body so as to provide a variety of electrical stimuli at different times during the recovery process.Type: GrantFiled: December 12, 2001Date of Patent: August 30, 2005Assignee: Alfred E. Mann Institute for Biomedical Engineering at the University of Southern CaliforniaInventors: Frances J. R. Richmond, Gerald E. Loeb, Tessa Gordon
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Patent number: 6909917Abstract: An implantable pulse generator includes a current steering capability that allows a clinician or patient to quickly determine a desired electrode stimulation pattern, including which electrodes of a group of electrodes within an electrode array should receive a stimulation current, including the amplitude, width and pulse repetition rate of such current. Movement of the selected group of electrodes is facilitated through the use of remotely generated directional signals, generated by a pointing device, such as a joystick. As movement of the selected group of electrodes occurs, current redistribution amongst the various electrode contacts takes place. The redistribution of stimulus amplitudes utilizes re-normalization of amplitudes so that the perceptual level remains fairly constant. This prevents the resulting paresthesia from falling below the perceptual threshold or above the comfort threshold.Type: GrantFiled: August 15, 2003Date of Patent: June 21, 2005Assignee: Advanced Bionics CorporationInventors: Carla Mann Woods, David K. L. Peterson, Paul M. Meadows, Gerald E. Loeb
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Patent number: 6895279Abstract: Many patients suffer from diseases and surgical damage that result in failure of the stomach and intestinal tract to contract and relax normally in order to transfer contents distally. Electrical stimulation applied to one or more sites on the surface of the gastrointestinal viscera can treat this problem by triggering or altering muscle contractility. The present invention provides such stimulation by implanting leadless microstimulators in or on the walls of the viscera that can be programmed or controlled from a source outside the body.Type: GrantFiled: September 14, 2001Date of Patent: May 17, 2005Assignee: Alfred E. Mann Institute for Biomedical Engineering at the University of Southern CaliforniaInventors: Gerald E. Loeb, Frances J. R. Richmond
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Patent number: 6887667Abstract: Many diseases are related to variations in the genetically specified structure of proteins synthesized by cells. Genetic engineering is now able to identify the structural variations and to introduce new genes to synthesize more healthful proteins, but it is difficult actually to identify the specific protein or chemical variants in bodily fluids and extracts of tissues in order to diagnose diseases and to assess the effects of treatment. This invention provides apparatuses and methods which allow a user to finely discriminate between small variations in the structure, function and levels of specific biochemicals even when admixed with other biochemicals.Type: GrantFiled: December 18, 2001Date of Patent: May 3, 2005Assignee: Alfred E. Mann Institute for Biomedical Engineering at the University of Southern CaliforniaInventor: Gerald E. Loeb
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Publication number: 20040153127Abstract: Many individuals generate excessively loud snoring during their sleep, often to the point where others cannot tolerate sleeping in the same room with them. Most cases of snoring are caused by excessive bulk and flaccidity of soft tissues of the palate and uvula that vibrate as air flows past them. These palate and uvula contain muscles whose contractions can stiffen and displace the soft tissues so that they do not vibrate. The invention provides electrical stimulation that causes the oropharyngeal muscles to contract during sleep using one or more microstimulators injected into or near these muscles or the nerves which innervate them. The invention also provides methods of determining the anatomical structures implicated in snoring and testing such locations for effective placement and stimulation of muscle contraction to decrease the frequency or magnitude of snoring.Type: ApplicationFiled: January 15, 2004Publication date: August 5, 2004Applicant: Alfred E. Mann Institute for Biomedical Engineering at the University of Southern CalifornInventors: David C. Gordon, Gerald E. Loeb
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Patent number: 6735474Abstract: A method and system for treatment of incontinence and/or pelvic pain includes the injection or laparoscopic implantation of one or more battery- or radio frequency-powered microstimulators (10) beneath the skin of the perineum and/or adjacent the tibial nerve. The devices are programmed using radio-frequency control via an external controller (20, 30)) that can be used by a physician to produce patterns of output stimulation pulses judged to be efficacious by appropriate clinical testing to diminish symptoms. The stimulation program is retained in the microstimulator device (10) or external controller (20) and is transmitted when commanded to start and stop by a signal from the patient or caregiver.Type: GrantFiled: August 18, 2000Date of Patent: May 11, 2004Assignee: Advanced Bionics CorporationInventors: Gerald E. Loeb, Francis J. R. Richmond, Carla M. Mann, Michael A. Faltys, Todd K. Whitehurst, James P. McGivern