Patents by Inventor Gerhard Krammer

Gerhard Krammer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170265511
    Abstract: The invention relates to substance mixtures which contain (a) sodium carboxymethyl cellulose and (b) at least one bitter principle selected from the group consisting of xanthines, phenolic glycosides, flavanoid glycosides, hydrolysable or non-hydrolysable tannins, flavones and the glycosides thereof, caffeic acid and the esters thereof, terpenoid bitter principles, catechin, epicatechin, epigallocatechin, gallocatechin, gallocatechin-3-gallate, leucine, isoleucine, valine, tryptophan and phenylalanine, protein hydrolysates, peptides and metal salts and their mixtures, and optionally (c) dextrins, with the proviso that the components (a) and (b) are in the weight ratio of from 1:1 to 1:1,000.
    Type: Application
    Filed: June 3, 2015
    Publication date: September 21, 2017
    Inventors: Sabine Widder, Langer Katrin, Gerhard Krammer, Olga Paull, Cornelia Homner
  • Publication number: 20170196898
    Abstract: Suggested is a medicament which is particularly useful for preventing, curing or abating of cough and inflammations of the respiratory system, comprising or consisting of active pharmaceutical ingredients and 1,3-propandiol.
    Type: Application
    Filed: June 27, 2015
    Publication date: July 13, 2017
    Applicant: Symrise AG
    Inventors: Donna Rosa, Jakob Ley, Gerhard Krammer, Deborah Kennison
  • Publication number: 20170190727
    Abstract: The invention relates to novel substance mixtures which can be used as aroma compositions to enhance the sweet taste of oral preparations.
    Type: Application
    Filed: June 11, 2015
    Publication date: July 6, 2017
    Applicant: Symrise AG
    Inventors: Gerhard Krammer, Christoph SABATER, Thomas RIESS, Jakob LEY, Thorsten GEIßLER
  • Patent number: 9675568
    Abstract: Suggested is a pharmaceutical composition, comprising menthane carboxylic acid-N-(4-methoxy-phenyl)-amide.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: June 13, 2017
    Assignee: Symrise AG
    Inventors: Gerhard Krammer, Sven Siegel, Silke Middendorf
  • Publication number: 20170135982
    Abstract: The invention relates to compounds of formula (I) or the salts thereof, said compounds of formula (I) being selected from among the group consisting of homoeriodictyol (1), eriodictyol (2), hesperetin (3) and sterubin (4), for use in the treatment of an ailment which can be alleviated or prevented by influencing the serotonin level and the concentration of free fatty acids in the blood.
    Type: Application
    Filed: July 26, 2015
    Publication date: May 18, 2017
    Applicant: Symrise AG
    Inventors: Veronika Somoza, Barbara Rohn, Kathrin Liszt, Marc Pignitter, Christina Hochkogler, Jakob Ley, Sabine Widder, Gerhard Krammer
  • Patent number: 9629795
    Abstract: Substance mixtures are proposed, comprising (a) terpenes, (b) propane-1,3-diol, and optionally (c) active substances selected from the group consisting of (c1) rebaudiosides or plant extracts comprising them, (c2) steviosides or plant extracts comprising them, (c3) monatin, (c4) naringin, (c5) chalcones and hydrochalcones, (c6) mogrosides or plant extracts comprising them, (c7) rubusosides or plant extracts comprising them, and (c8) glycyrrhizic acid or plant extracts comprising it.
    Type: Grant
    Filed: March 30, 2015
    Date of Patent: April 25, 2017
    Assignee: Symrise AG
    Inventors: Gerhard Krammer, Sven Siegel, Deborah Kennison
  • Patent number: 9468225
    Abstract: Suggested are new compositions for oral ingestion, comprising at least one active agent from the group of alkamides. The compositions which are orally ingested reduce the uptake of free fatty acids in the adipocytes and at the same time stimulate the release of serotonin and dopamine, which leads to a reduction of appetite, a feeling of satiety and a positive mood. In doing so, the new compositions are thus perfectly suitable to counteract any undesired gain of weight.
    Type: Grant
    Filed: February 12, 2014
    Date of Patent: October 18, 2016
    Assignee: Symrise AG
    Inventors: Jakob Ley, Sabine Widder, Veronika Somoza, Barbara Rohm, Matthias Zaunschirm, Gerhard Krammer
  • Publication number: 20160295892
    Abstract: Suggested is a mixture of matter, comprising: (a) steviol glycosides, (b) starch degradation products and (c) one or more phenolic sweetness-enhancing aroma substances selected from the group formed by hesperetin, phloretin, 1-(2,4-dihydroxyphenyl)-3-(3-hydroxy-4-methoxyphenyl)propan-1-one, 7,3-dihydroxy-4?-methoxyflavan and 5-hydroxy-4-(4-hydroxy-3-methoxyphenyl)-7-methoxy-2-chromanone. On condition that components (a+b) and (c) are present in a ratio by weight of from 1.
    Type: Application
    Filed: October 26, 2014
    Publication date: October 13, 2016
    Applicant: Symrise AG
    Inventors: Uwe SCHÄFER, Gerhard KRAMMER, Gerald GLAUBITZ, Thomas RIESS, Jakob LEY, Susanne PAETZ
  • Publication number: 20160281118
    Abstract: The invention relates to providing both fermentative and biotechnological methods for producing 3,4-methylized cinnamic acids, 3,4-methylized cinnamic acid esters, 3,4-dimethoxyphenethylamine, and 4-methylized cinnamic acid amides using a 4?-O-methyltransferase, optionally in combination with further enzymes, wherein the enzymes are selected by means of metabolic engineering and operation have been adapted by targeted optimization, and compositions obtained by means of the method. The invention further relates to vector systems, recombinant microorganisms or fungi, and specific nucleic acid segments and polypeptides.
    Type: Application
    Filed: February 1, 2016
    Publication date: September 29, 2016
    Inventors: GERHARD KRAMMER, JAKOB PETER LEY, KATRIN GEIßLER, TORSTEN GEIßLER, FRAUKE GOMOLL, PETER WELTERS, GUIDO JACH, LUDGER WESSJOHANN
  • Patent number: 9445606
    Abstract: The invention provides the use of a 4-hydroxydihydrochalcone of the formula (I) wherein R1, R2, R3 and R4 each, independently, represent H, OH or O-alkyl, with the proviso that at least one of the groups R1, R2 or R3 represents OH, a salt of such a 4-hydroxydihydrochalcone of the formula (I), a mixture containing or consisting of two or more different 4-hydroxydihydrochalcones of the formula (I), wherein R1, R2, R3 and R4 are each defined in the way given above, a mixture containing or consisting of salts of two or more different 4-hydroxydihydrochalcones of the formula (I), wherein R1, R2, R3 and R4 are each defined in the way given above or a mixture containing or consisting of a 4-hydroxydihydrochalcone of the formula (I) or two or more different 4-hydroxydihydrochalcones of the formula (I), wherein R1, R2, R3 and R4 are each defined in the way given above, and a salt of a 4-hydroxydihydrochalcone of the formula (I) or two or more salts of different 4-hydroxydihydrochalcones of the formula
    Type: Grant
    Filed: March 21, 2007
    Date of Patent: September 20, 2016
    Assignee: SYMRISE AG
    Inventors: Gerhard Krammer, Jakob Ley, Thomas Riess, Martin Haug, Susanne Paetz, Günter Kindel, Ralph Schmidtmann
  • Patent number: 9386787
    Abstract: Preparations for oral consumption are proposed, comprising (a) lactic acid 1-menthyl ester of the general formula (I) its stereoisomers or mixtures thereof, (b) at least one substance having a bitter, astringent and/or metallic taste impression, and optionally (c) further flavorings.
    Type: Grant
    Filed: November 7, 2013
    Date of Patent: July 12, 2016
    Assignee: Symrise AG
    Inventors: Gerhard Krammer, Jakob Ley, Katja Obst, Katharina Reichelt
  • Patent number: 9359622
    Abstract: A method for production of a dihydrochalcone, especially of phloretin, using a transgenic microorganism, containing a nucleic acid section (a), comprising or consisting of a gene coding for a bacterial chalcone isomerase, and/or a nucleic acid section (a?), comprising or consisting of a gene coding for a plant chalcone isomerase, and a nucleic acid section (b), comprising or consisting of a gene coding for a bacterial enoate reductase, corresponding transgenic microorganisms, containing a nucleic acid section (a), comprising or consisting of a gene coding for a bacterial chalcone isomerase, and/or a nucleic acid section (a?), comprising or consisting of a gene coding for a plant chalcone isomerase, and/or a nucleic acid section (b), comprising or consisting of a gene coding for a bacterial enoate reductase, and host cells, containing one or more identical or different such vectors.
    Type: Grant
    Filed: July 30, 2013
    Date of Patent: June 7, 2016
    Assignee: SYMRISE AG
    Inventors: Jens Michael Hilmer, Egon Gross, Gerhard Krammer, Jakob Peter Ley, Mechthild Gall, Uwe Bornscheuer, Maren Thomsen, Christin Peters, Patrick Jonczyk, Sascha Beutel, Thomas Scheper
  • Patent number: 9345255
    Abstract: Compositions, comprising menthofuran and selected menthol compounds which feature improved flavor and odor properties, are provided and, in addition, the production of compositions, specifically, of emulsions with an improved storage stability.
    Type: Grant
    Filed: December 27, 2012
    Date of Patent: May 24, 2016
    Assignee: Symrise AG
    Inventors: Günter Kindel, Gerhard Krammer, Sven Siegel
  • Patent number: 9332783
    Abstract: The present invention relates to the use of one or more compounds of the formulae and/or pharmaceutically acceptable salts thereof for inhibiting the oxidation of fatty acids and/or triacylglycerols; and/or the rancidification of products that includes one or more of fatty acids and/or one or a plurality of triacylglycerols; and/or chemical and/or sensory changes of products that includes one or more of fatty acids and/or one or a plurality of triacylglycerols, caused by the action of the oxygen of the air. Corresponding mixtures and orally consumable preparations and methods are also described.
    Type: Grant
    Filed: April 14, 2013
    Date of Patent: May 10, 2016
    Assignee: SYMRISE AG
    Inventors: Andreas Degenhardt, Gerhard Krammer, Michael Backes
  • Publication number: 20150342238
    Abstract: Suggested is a dry food composition for mixing with a drinkable liquid, said composition comprising (a) carbohydrates, (b) proteins, (c) fats, and optionally (d) probiotic micro-organisms and/or prebiotics, and (e) vitamins, minerals, texturisers, fibres, sweeteners, flavourings and/or colorants, whereby said composition shows a particle size distribution wherein (i) about 90% b.w. of the particles show an average diameter of less than about 400 ?m, (ii) about 50% b.w. of the particles show an average diameter of less than about 80 ?m, and (iii) about 10% b.w. of the particles show an average diameter of less than about 10 ?m.
    Type: Application
    Filed: July 6, 2012
    Publication date: December 3, 2015
    Applicant: Symrise AG
    Inventors: Sabine Widder, Gerhard Krammer, Kathrin Langer, Cornelia Hommer
  • Publication number: 20150272864
    Abstract: Substance mixtures are proposed, comprising (a) terpenes, (b) propane-1,3-diol, and optionally (c) active substances selected from the group consisting of (c1) rebaudiosides or plant extracts comprising them, (c2) steviosides or plant extracts comprising them, (c3) monatin, (c4) naringin, (c5) chalcones and hydrochalcones, (c6) mogrosides or plant extracts comprising them, (c7) rubusosides or plant extracts comprising them, and (c8) glycyrrhizic acid or plant extracts comprising it.
    Type: Application
    Filed: March 30, 2015
    Publication date: October 1, 2015
    Inventors: Gerhard Krammer, Sven Siegel, Deborah Kennison
  • Patent number: 9029166
    Abstract: The present invention relates to a method of identifying a natural substance that is capable of complexation with Ni2+, Cu2+ and/or Fe2+ ions, wherein an extract containing natural substances is led over a stationary phase loaded with Ni2+, Cu2+ and/or Fe2+ ions, which is suitable for immobilized metal affinity chromatography (IMAC).
    Type: Grant
    Filed: August 29, 2011
    Date of Patent: May 12, 2015
    Assignee: Symrise AG
    Inventors: Andreas Degenhardt, Gerhard Krammer, Nicole Schulze
  • Publication number: 20150086693
    Abstract: There are proposed substance mixtures comprising (a) 20 to 80% by weight of monocyclic terpenes and (b) 80 to 20% by weight of active substances selected from the group consisting of rebaudiosides or plant extracts comprising them, steviosides or plant extracts comprising them, naringin dihydrochalcone, mogrosides or plant extracts comprising them, rubusosides or plant extracts comprising them.
    Type: Application
    Filed: April 25, 2013
    Publication date: March 26, 2015
    Inventors: Gerhard Krammer, Sven Siegel, Günter Kindel
  • Patent number: 8828469
    Abstract: An individual alkamide and/or a mixture having two or more different alkamides, is disclosed for changing, masking or reducing the unpleasant flavor impression of an unpleasant-tasting substance or mixture of substances. The alkamide can be trans-pellitorine; cis-pellitorine; 2Z,4Z- or 2Z,4E-decadienoic acid-N-isobutylamide; 2E,4E-decadienoic acid-N-([2S]-2-methylbutyl)amide; 2E,4E-decadienoic acid-N-([2R]-2-methylbutylamide); 2E,4Z-decadienoic acid-N-(2-methylbutyl)amide; achilleamide; sarmentine; 2E- or 3E-decenoic acid-N-isobutylamide; 3E-nonenoic acid-N-isobutylamide; spilanthol; homospilanthol; 2E,6Z,8E-decatrienoic acid-N-([2R]-2-methylbutyl)amide; 2E- or 2Z-decen-4-oic acid-N-isobutylamide; ?-sanshool; ?-hydroxysanshool; ?-hydroxysanshool; ?-hydroxysanshool; ?-hydroxyisosanshool; ?-dehydrosanshool; ?-sanshool; bungeanool; isobungeanool; dihydrobungeanool; or tetrahydrobungeanool, or combinations thereof.
    Type: Grant
    Filed: November 6, 2008
    Date of Patent: September 9, 2014
    Assignee: Symrise AG
    Inventors: Kathrin Langer, Jakob Ley, Gerald Reinders, Günter Kindel, Gerhard Krammer
  • Publication number: 20140234412
    Abstract: Suggested are new compositions for oral ingestion, comprising at least one active agent from the group of alkamides. The compositions which are orally ingested reduce the uptake of free fatty acids in the adipocytes and at the same time stimulate the release of serotonin and dopamine, which leads to a reduction of appetite, a feeling of satiety and a positive mood. In doing so, the new compositions are thus perfectly suitable to counteract any undesired gain of weight.
    Type: Application
    Filed: February 12, 2014
    Publication date: August 21, 2014
    Applicant: Symrise AG
    Inventors: Jakob Ley, Sabine Widder, Veronika Somoza, Barbara Rohm, Matthias Zaunschirm, Gerhard Krammer