Abstract: The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.

Abstract: The disclosure provides compounds of formula I, II, III, IV, and V, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.

Abstract: A perforated plate for use in a high g vibratory device in the separation of solid particles within a slurry. The plate is rigid and has perforations with a span of no greater than 3/16 inch.

Abstract: The disclosure provides compounds of formula I, II, III, IV, and V, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.

Abstract: The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.

Abstract: The disclosure provides compounds of formula I, II, III, IV, and V, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.

Abstract: A seal can have a middle portion, an upper lip, and a lower lip. The upper lip has a configuration with an upper end portion, an upper top portion, and an upper bottom portion with a void space defined in part by the upper end portion, the upper top portion, and the upper bottom portion. The lower lip can have a configuration with an upper end portion, a lower top portion, and an upper bottom portion with a void space defined in part by the lower end portion, the lower top portion, and the lower bottom portion. A middle portion connects the upper lip and the lower lip.

Abstract: The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.

Abstract: The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.

Abstract: A process of separating a fluid and fibrous material from wet fibrous matter can include: 1) Putting the wet fibrous matter onto a vibrating screen device which has a plurality of screens in a sequential configuration. Each screen has a perforated center portion with elliptically shaped perforations with a span of no greater than 0.1 inches. 2) Vibrating each screen to expedite separation of the fibrous material and the fluid from the wet fibrous matter on each screen such that the fluid separated from the wet fibrous matter on each screen passes through the perforations and the fibrous material conveys along the screen. 3) Conveying the fibrous material from a screen that is sequentially before to a screen that is sequentially after for further separating the fluid from the fibrous material.

Abstract: A process of separating a fluid and mill scale particles from mill slag can include: 1) Putting the mill slag onto a vibrating screen device which has a plurality of screen assemblies in a sequential configuration. Each screen assembly comprises a screen having a perforated center portion with elliptically shaped perforations with a span of no greater than 0.175 inches. 2) Vibrating each screen assembly to expedite separation of the mill scale particles and the fluid from the mill slag on each screen such that the fluid separated from the mill slag on each screen passes through the perforations and the mill scale particles convey along the screen. 3) Conveying the mill scale particles from a screen assembly that is sequentially before to a screen assembly that is sequentially after for further separating the fluid from the mill scale particles.

Abstract: The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.

Abstract: The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.

Abstract: A vibrating screen device has a screen assembly and a basket. The screen assembly comprises a plurality of screens disposed within the vibrating screen device. The plurality of screens are constructed and arranged in a stepped down configuration such that each screen that is arranged below an adjacent screen in a stepped down configuration is at least partially overlapped by the adjacent screen arranged above. Each screen has a middle portion and a perimeter portion. The middle portion is porous, and the perimeter portion is substantially thicker than the middle portion.

Abstract: The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.

Abstract: A counter mechanism useable with a dry powder inhaler is disclosed. The mechanism features first and second indicator members rotatable about a central axis. The indicator members have counting indicia visible to indicate inhaler doses remaining or dispensed. A coupling transmits rotary motion from the inhaler to the second indicator member when the inhaler is charged with a dose. A slave wheel, rotatable about an axis offset from the central axis, has a drive transfer wheel on one face and a gear on an opposite face. The gear engages the second indicator member, the drive transfer wheel intermittently engages and rotates the first indicator member in response to rotary motion of the second indicator member.

Abstract: The invention encompasses a series bicyclic pyrimidinone compounds of Formula I which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.

Abstract: A rotatably actuated counter is disclosed. The counter includes a ratchet driven unit wheel nested within a tens wheel. Each wheel has a radial face displaying counting indicia. The tens wheel is transparent, allowing the indicia on the unit wheel to be viewed adjacent to the indicia on the tens wheel to provide a total count. A slave wheel is positioned between the unit and tens wheels. A gear on one face of the slave wheel engages gear teeth on the tens wheel. A Geneva mechanism on the other face is engaged by a foot on the unit wheel once per rotation. The wheels are rotatably mounted within a housing having a sidewall with a window through which the count indicia may be viewed. The unit wheel rotates in ten increments and then rotates the tens wheel through one increment by engaging and rotating the slave wheel.

Abstract: The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.

Abstract: The disclosure provides compounds of formula I, II, III, IV, and V, including their salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.