Abstract: A pixel array, an image sensor, and a self-checking method of the image sensor are provided. The pixel array includes a photosensitive pixel region, a first reference pixel region and/or a second reference pixel region; the photosensitive pixel region includes M rows and N columns of pixels arranged in an array; the first reference pixel region includes n columns of first reference pixels disposed corresponding to N columns of pixels of the photosensitive pixel region; the second reference pixel region includes m rows of the second reference pixels disposed corresponding to the M rows of pixels of the photosensitive pixel region. The first reference pixel region and/or the second reference pixel region can be used to implement a real-time self-checking function of the readout circuit and/or the control circuit in the image sensor, check in real time whether the image signal output by the image sensor is correct.

Abstract: Embodiments of the present disclosure provides methods and systems for preparing a cathode component. The method may include obtaining a three-dimensional (3D) model of the cathode component; obtaining a predetermined parameter, wherein the predetermined parameter includes at least one of a scanning direction of laser, an energy distribution of laser, an output power of laser, or a scanning speed of laser; and controlling a 3D printer to perform, based on the 3D model and the predetermined parameter, a laser scanning on a raw material to obtain the cathode component.

Abstract: According to one embodiment, a first phrase having one or more keywords is received to be added to a phrase blacklist, where the first phrase has been determined to be related to unwanted content. An analysis is performed on the keywords of the first phrase to identifying a set of one or more related phrases that are related to the first phrase. The first phrase and the set of related phrases are added in the phrase blacklist. The phrase blacklist contains a plurality of phrases that have been determined to be related to unwanted content. The phrase blacklist is utilized to prevent a content item from appearing in a search result, in response to a search query having a phrase matching at least one of the phrases in the phrase backlist.

Abstract: A clothes washing machine includes a cabinet defining an interior and having a top wall with a dispenser opening, and a water inlet box located within the interior and having a storage cartridge chamber accessible through the dispenser opening. The storage cartridge can be removably mountable within the storage cartridge chamber through the dispenser opening.

Abstract: The present disclosure provides compounds of Formula (I), and pharmaceutically acceptable salts, solvates, hydrates, polymorphs, co-crystals, tautomers, stereoisomers, isotopically labeled derivatives, and prodrugs thereof. The provided compounds may be kinase (e.g., HCK, BTK, LYN, BLK, FRK) inhibitors. Also provided are pharmaceutical compositions and kits including the provided compounds. Further provided are methods of using the provided compounds, pharmaceutical compositions, and kits (e.g., for treating diseases (e.g., proliferative diseases) in a subject in need thereof).

Abstract: The embodiments of the present disclosure disclose a method for processing a remote interference measurement signal, a base station and a storage medium. The method includes that: a first base station determines configuration information of an interference measurement signal; and the first base station transmits the interference measurement signal according to the configuration information of the interference measurement signal.

Abstract: A temperature sensor of a thermal monitoring system is provided for use in power distribution systems. The temperature sensor comprises ceramic printed circuit board (PCB) and a terminal. The ceramic PCB includes a temperature sensing element disposed on a side of the ceramic PCB. The terminal is configured to be fixed directly in contact with a measured point and is directly in touch with the ceramic PCB such that heat is conducted from the terminal, through the ceramic PCB and then to the temperature sensing element. The temperature sensing element is configured to generate an electrical signal in response to the heat such that the electrical signal is sent through a pair of lead wires to a controller for monitoring a temperature. The temperature sensor further comprises an overmolded plastic material to seal a portion of the terminal, the ceramic PCB in its entirety and a portion of the pair of lead wires to ensure a desired physical strength and a desired dielectric strength.

Abstract: A circuit breaker with enhanced convection and cooling comprises a housing having a first portion and a second portion. The circuit breaker further comprises one or more first orientation features formed onto the first portion of the housing. The circuit breaker further comprises one or more second orientation features formed onto the second portion of the housing such that the one or more first orientation features are different from the one or more second orientation features and the first portion of the housing is different than the second portion of the housing. The one or more first orientation features and the one or more second orientation features are assembled together to form air channels to allow air to go in and out while preventing a solid object from protruding and from touching inside components of the circuit breaker.

Abstract: A vehicle includes an electric machine, a battery, an electrical circuit, an overcharge limit device, and a controller. The electric machine is configured to propel the vehicle. The battery has a plurality of cells and is configured to provide electrical power to the electric machine. The electrical circuit is configured to deliver the electrical power from the battery to the electric machine. The overcharge limit device is configured to individually disconnect each of the plurality cells from the circuit in response to an internal pressure of a respective cell exceeding a pressure threshold. The controller is programmed to, in response to detecting a first set of parameters that are indicative of a first of the cells being disconnected from the electrical circuit via the overcharge limit device, discontinue control the first of the cells.

Abstract: An adjustment mechanism for adjusting a formed staple height of a suture staple in a stapler comprises a first handle portion and a second handle portion. The first handle portion comprises a cartridge support located at a distal end, a cartridge assembly, a drive assembly, and the adjustment mechanism for adjusting a formed staple height of a suture staple, and the second handle portion comprises an anvil located at a distal end. The cartridge assembly comprises suture staples, and the drive assembly can drive a suture staple to leave the cartridge assembly to reach the anvil to be pressed and formed. The adjustment structure adjusts a distance between the drive assembly and the anvil to adjust a formed staple height of a suture staple in a stapler. This application further relates to a stapler, comprising the adjustment mechanism for adjusting a formed staple height of a suture staple in a stapler.

Abstract: A solid-state circuit breaker comprises a breaker housing and an air gap driving mechanism that is a permanent magnet based. The air gap driving mechanism includes a pair of opposing contacts, a first permanent magnet to generate a static magnetic field and a coil actuator to generate a dynamic magnetic field. The first permanent magnet and the coil actuator are positioned relative to each other such that the dynamic magnetic field generated by the coil actuator can either enhance or cancel the static magnetic field of the first permanent magnet. Hence a combination of the static magnetic field from the first permanent magnet and the dynamic magnetic field from the coil actuator can either drive the pair of opposing contacts open or drive the pair of opposing contacts close.

Abstract: Provided herein are methods of treating diseases (e.g., proliferative disease (e.g., cancer (e.g., breast cancer, colon cancer, testicular cancer, CNS cancer, stomach cancer, lymphoma (e.g., B-cell lymphoma (e.g., lymphoplasmacytic lymphoma (e.g., IgM secreting lymphoplasmacytic lymphoma (i.e., Waldenstrom's Macroglobulinemia), non-IgM secreting lymphoplasmacytic lymphoma)), diffuse large B-cell lymphoma (e.g., activated B-cell-like (ABC)-DLBCL, germinal center B-cell-like (GBC)-DLBCL), follicular lymphoma, marginal zone B-cell lymphoma, small lymphocytic lymphoma, mantle cell lymphoma), and leukemia (e.g., chronic lymphocytic leukemia (CLL), acute lymphoblastic leukemia, myelogenous leukemia (e.g., chronic myelogenous leukemia, acute myelogenous leukemia))))) comprising administering to the subject in need thereof a therapeutically effective amount of Compound (I). Further provided are methods for treating disease resistant to treatment with BTK inhibitors (e.g., ibmtinib).

Abstract: This application relates to apparatus and methods for automatically determining query corrections based on prior interactions of users with a search query. In some examples, a computing device receives a search query from a user, and returns a query correction to the user in response to the search query. The computing device obtains engagement data corresponding to the query correction from the user. The computing device also updates one of a query-correction database and a typo-candidate database based at least in part on the engagement data. When the computing device receives the search query from another user, it corrects the search query from the another user using the query-correction database and the typo-candidate database.

Abstract: Provided herein are bifunctional compounds with a moiety (e.g., lenalidomide, thalidomide) that is a binder of an E3 ubiquitin ligase (e.g., Cereblon) and another moiety that is a binder of a kinase (e.g., HCK, BTK) to induce degradation of the kinase (e.g., HCK, BTK). Also provided are pharmaceutical compositions comprising the bifunctional compounds, and methods of treating and/or preventing diseases (e.g., proliferative diseases (e.g., non-Hodgkin's lymphoma, Burkitt's lymphoma, Waldenstrom macroglobulinemia, MYD88-mutated Waldenstrom macroglobulinemia, activated B-cell diffuse large B-cell lymphoma, leukemia)), inflammatory disease, or other diseases associated with MYD88 mutations). Provided also are methods of inducing the degradation of a kinase (e.g., HCK, BTK) in a cell in a biological sample or subject by administering the bifunctional compound or composition described herein.

Abstract: The present invention relates to recombinant cyanobacterial cells for the production of a chemical compound of interest. In particular, the present invention relates to genetic modifications that introduce one or more heterologous phosphopantetheinyl transferases (PPTases) into a cyanobacterial cell. These cells can, optionally, further comprise heterologous carrier protein and nucleic acid constructs that provide the cyanobacterial cells with the capability of producing chemicals of interest or compounds of interest, such secondary metabolites polyketides, nonribosomal peptides and their hybrids, the three major families of bioactive natural products, of cyanobacteria and other bacterial phyla, secondary metabolites analogs, and unnatural compounds.

Abstract: An permissionless blockchain consensus method with adjusting block weight, comprising: setting weights of all blocks in the permissionless blockchain to the same initial value; determining parent edges(forward reference-edges) of any one of blocks in the permissionless blockchain according to the blockchain topology; detecting whether a first judgment block x is in blocks contained by the parent edge of a block b; if yes, determining that the block b is an unstable block and transferring to next step, otherwise, determining the block b is a stable block and transferring to a pivot chain consensus step; and detecting whether a second judgment blocky is in the stable block contained by the parent edge of the block b; if yes, determining the block b is a readjusted block and transferring to a weight adjustment step, otherwise, determining the block b is a stable block and transferring to the pivot chain consensus step.

Abstract: The present application provides a pixel driving circuit and a liquid crystal display panel. The pixel driving circuit comprises a main pixel electrode driving module, a sub-pixel electrode driving module, a first potential regulation module, and a second potential regulation module.

Abstract: An association handling method and device are provided. The method includes: determining one or more TNL addresses of a CU; and establishing multiple TNL associations between a DU and the CU according to the one or more TNL addresses.

Abstract: Provided are amino acid sequences capable of binding to and inhibiting a Cas protein's ability to bind to a nucleic acid molecule, thereby inhibiting the Cas protein's function in genome editing. Such Cas protein inhibitors, which can be comprised of a major coat protein (G8P), an extracellular region of the G8P (G8PEX), or a biological equivalent, are useful in improving the specificity of Cas protein-based genome editing procedures.

Abstract: A disassemblable anastomosis clamp, at least comprising a clamp frame and a first clasping part and a second clasping part connected to the clamp frame. The first clasping part and/or the second clasping part is detachably connected to the clamp frame. At least one clasping part is designed to be detachable from the clamp frame, and thus when removing the anastomosis clamp, the detachable clasping part can be separated from the clamp frame first and then moved away, allowing the anastomosis clamp to be removed safely and conveniently.