Abstract: The present invention relates to a method of determining a protein in a sample and the use of the method for the identification of aptamer target proteins.

Abstract: The present invention relates to compounds according to general formula (I), pharmaceutical compositions comprising compounds according to general formula (I) and the use of the compounds for the treatment of a bacterial infection, particularly for use as an antibiotic.

Abstract: The invention relates to an eccentric gear arrangement of a motor-driven, hand-guided hedge trimmer (1). The eccentric gear arrangement includes two shearing blades (2, 3) driven in mutually opposite directions over a displacement path (a). Each shearing blade has a connecting link (4, 5) as well as an eccentric wheel (6) having a drive wheel (7) and two eccentrics (8, 9). The eccentric wheel (6) rotates about a rotational axis (10). The two connecting links (4, 5) lie directly above one another. The two eccentrics (8, 9) are arranged on the same side of the drive wheel (7) and engage each in one of the two connecting links (4, 5). The two shearing blades (2, 3) have contact pressure surfaces (11, 12) in the region of their two connecting links (4, 5) and are offset with respect to each other in such a manner that they are exposed at least over a portion of the displacement path (a). Two downholders (13, 14) are provided which act each on one of the assigned contact pressure surfaces (11, 12).

Abstract: The present invention relates to compounds according to general formula (I), pharmaceutical compositions comprising compounds according to general formula (I) and the use of the compounds for the treatment of a bacterial infection, particularly for use as an antibiotic.

Abstract: The invention relates to an eccentric gear arrangement of a motor-driven, hand-guided hedge trimmer (1). The eccentric gear arrangement includes two shearing blades (2, 3) driven in mutually opposite directions over a displacement path (a). Each shearing blade has a connecting link (4, 5) as well as an eccentric wheel (6) having a drive wheel (7) and two eccentrics (8, 9). The eccentric wheel (6) rotates about a rotational axis (10). The two connecting links (4, 5) lie directly above one another. The two eccentrics (8, 9) are arranged on the same side of the drive wheel (7) and engage each in one of the two connecting links (4, 5). The two shearing blades (2, 3) have contact pressure surfaces (11, 12) in the region of their two connecting links (4, 5) and are offset with respect to each other in such a manner that they are exposed at least over a portion of the displacement path (a). Two downholders (13, 14) are provided which act each on one of the assigned contact pressure surfaces (11, 12).

Abstract: The invention relates to a sealed, sterile system for filtering fluids, in particular whole blood. The system comprises a first collapsible container for receiving the fluid to be filtered and a second collapsible container for receiving the filtered fluid, both containers interconnected by a fluid line, in which a filter and a third container, for deaeration, are located. The first collapsible container contains a predetermined quantity of air, which is sufficient to ensure that no blood remains in the filter and the adjacent tube line sections when the whole blood is transferred from the first container into the second container. The air that is present in the second container, after the whole blood has been filtered, is transferred to the deaeration container.

Abstract: The invention concerns a fuel cell comprising an anode chamber, a cathode chamber and a cavity for the electrolytic space, as well as combustion gas supply conduits and carbon dioxide and water discharge conduits for the anode chamber, and, for the cathode chamber, oxygen and carbon dioxide supply conduits and discharge conduits for residual oxygen and residual carbon dioxide. The anode chamber and the cathode chamber receive a metal sponge, the cathode chamber housing a metal or ceramic sponge. Said fuel cell is subdivided into an anode chamber, an outer cathode chamber and a median cathode chamber, separate cavities for electrolytic space located between the anode chamber and the median cathode chamber and the median cathode chamber and the outer cathode chamber.

Abstract: The invention concerns a fuel cell comprising an anode chamber, a cathode chamber and a cavity for the electrolytic space, as well as combustion gas supply conduits and carbon dioxide and water discharge conduits for the anode chamber, and, for the cathode chamber, oxygen and carbon dioxide supply conduits and discharge conduits for residual oxygen and residual carbon dioxide. The anode chamber and the cathode chamber receive a metal sponge, the cathode chamber housing a metal or ceramic sponge. Said fuel cell is subdivided into an anode chamber, an outer cathode chamber and a median cathode chamber, separate cavities for electrolytic space located between the anode chamber and the median cathode chamber and the median cathode chamber and the outer cathode chamber.

Abstract: The invention relates to a sealed, sterile system for filtering fluids, in particular whole blood. The system comprises a first collapsible container for receiving the fluid to be filtered and a second collapsible container for receiving the filtered fluid, both containers interconnected by a fluid line, in which a filter and a third container, for deaeration, are located. The first collapsible container contains a predetermined quantity of air, which is sufficient to ensure that no blood remains in the filter and the adjacent tube line sections when the whole blood is transferred from the first container into the second container. The air that is present in the second container, after the whole blood has been filtered, is transferred to the deaeration container.

Abstract: A walk-behind sweeper has at least one sweeping roller and an air-cooled drive motor having a drive shaft and driving in rotation the at least one sweeping roller. At least one fan wheel conveys cooling air to the drive motor wherein the at least one fan wheel is driven by the drive shaft. A dirt collecting chamber is provided into which swept-up material that is swept up by the at least one sweeping roller is conveyed. The at least one fan wheel has an intake side connected by a flow connection to a working area of the sweeper so that at least a portion of the cooling air stream for the drive motor is taken in from the working area of the sweeper.

Abstract: A portable handheld work apparatus has a motor housing (2) wherein a drive motor (18) is mounted. The drive motor (18) drives a work tool. The work tool is operatively connected via a drive shaft (8) to the drive motor (18). A coupling device (65, 66, 67) is mounted in the operative connection between the drive shaft (8) and the work tool in order to avoid a transmission of vibrations of the work tool to the drive shaft (8). The coupling device (65, 66, 67) permits a limited movement of the work tool relative to the drive shaft (8).

Abstract: A rotatably driveable work tool (1) of a motor-driven work apparatus has, at a front end (2, 3), an end plate (5, 6) lying perpendicularly to a rotational axis (4). The end plate (5, 6) has an outer diameter (DR) which is less than a flight circular diameter (DF) of the work tool (1). The end plate (5, 6) is configured as a roll-up protective ring (8) which extends in a radial direction (14) from an inner diameter (DI) to the outer diameter (DR). The roll-up protective ring has an axially-extending component from the work tool (1) outwardly.

Abstract: A carrying system for an implement, comprising a carrying arm and a receiving device held on the carrying arm for receiving the guide rod of the implement. In a first state, the receiving device is adapted to fix the guide rod in a longitudinal direction thereof. In a second state, the receiving device is displaceable in the longitudinal direction of the guide rod.

Abstract: A rotatably driveable work tool (1) of a motor-driven work apparatus has, at a front end (2, 3), an end plate (5, 6) lying perpendicularly to a rotational axis (4). The end plate (5, 6) has an outer diameter (DR) which is less than a flight circular diameter (DF) of the work tool (1). The end plate (5, 6) is configured as a roll-up protective ring (8) which extends in a radial direction (14) from an inner diameter (DI) to the outer diameter (DR). The roll-up protective ring has an axially-extending component from the work tool (1) outwardly.

Abstract: A portable handheld work apparatus, such as a motorized cultivator (1) or the like, includes a frame (2) which extends essentially in the longitudinal direction (21) of the work apparatus. A drive motor (3) is fixed at one end (22) of the frame (2) and a work tool is driven by this drive motor. The opposite-lying end (23) includes at least a handle (7, 8) for guiding the work apparatus during the operation thereof. In order to make possible an ergonomic work posture of the operator, the handle (7, 8) lies facing away upwardly from the ground surface (42) in the work position of the motorized work apparatus. The work position is a position in which the work tool lies on the ground surface (42) to be worked.

Abstract: The invention relates to a nucleic acid, especially an isolated nucleic acid, that is capable of binding to a guanine nucleotide exchange factor for ADP ribosylation factors, and to the derivatives thereof.

Abstract: The invention relates to a device for controlling the amount of liquid substances received and discharged. It is an object of the invention to produce a device, enabling a plurality of different liquid substances to be received and discharged from micro or nano titer plates. According to the invention, it is possible to carry out one or more chemical or biological reactions in said device and to receive liquid substances with differing viscosity, as a result of capillary channels which are arranged at an equal distance from each other and are provided in a row, said channels being brought together in a communicative link with a chamber which is can be impinged upon by overpressure and underpressure, whereby the capillary channels are embedded in the plate and one sieve-type membrane is associated with the ends of the capillary channels at least on the inner side of the pressure chamber. According to the invention, an area is provided above each end of the capillary channels for receiving a liquid substance.

Abstract: A portable handheld work apparatus, such as a motorized cultivator (1) or the like, includes a frame (2) which extends essentially in the longitudinal direction (21) of the work apparatus. A drive motor (3) is fixed at one end (22) of the frame (2) and a work tool is driven by this drive motor. The opposite-lying end (23) includes at least a handle (7, 8) for guiding the work apparatus during the operation thereof. In order to make possible an ergonomic work posture of the operator, the handle (7, 8) lies facing away upwardly from the ground surface (42) in the work position of the motorized work apparatus. The work position is a position in which the work tool lies on the ground surface (42) to be worked.

Abstract: The present invention relates to an arrangement for producing, testing and archiving chemical or biological arrays bonded to a solid phase.

Abstract: A microcompartment array with a high compartment density and a process for producing the same are disclosed. To solve the problem that consists in arranging as many compartments as possible per surface unit and in providing a process for producing the same which excludes any mixture of adjacent compartment contents even when the compartments are overfilled, without having to change the way in which the compartments are filled, a first functional surface lining is applied on the inner walls of the compartment-like recesses, whereas the support surface areas which separate the individual compartment-like recesses from each other by their open sides are provided with a second functional surface lining having an effect opposite to that of the first functional surface lining.