Patents by Inventor Henrik Oestergaard

Henrik Oestergaard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polypeptides having peroxygenase activity
    Patent number: 9499801
    Abstract: The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. A polynucleotide encoding a peroxygenase was isolated from Pestalotiopsis virgatula.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: November 22, 2016
    Assignee: Novozymes A/S
    Inventors: Sara Landvik, Lars Henrik Oestergaard, Lisbeth Kalum
  • Polypeptides having peroxygenase activity
    Patent number: 9499802
    Abstract: The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. A polynucleotide encoding a peroxygenase was isolated from Pestalotiopsis virgatula.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: November 22, 2016
    Assignee: Novozymes A/S
    Inventors: Sara Landvik, Lars Henrik Oestergaard, Lisbeth Kalum
  • Polypeptides having peroxygenase activity
    Patent number: 9458435
    Abstract: The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. A polynucleotide encoding a peroxygenase was isolated from Penicillium chrysogenum.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: October 4, 2016
    Assignee: Novozymes A/S
    Inventors: Sara Landvik, Lars Henrik Oestergaard, Lisbeth Kalum
  • Polypeptides having peroxygenase activity
    Patent number: 9453207
    Abstract: The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. A polynucleotide encoding a peroxygenase was isolated from Thielavia terrestris.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: September 27, 2016
    Assignee: Novozymes A/S
    Inventors: Sara Landvik, Lars Henrik Oestergaard, Lisbeth Kalum
  • Stabilized Factor VIII Variants
    Publication number: 20160264645
    Abstract: The present invention relates to modified coagulation factors. In particular, the present invention relates to stabilized Factor VIII molecules conjugated with a half life extending moiety as well as use of such molecules.
    Type: Application
    Filed: June 1, 2016
    Publication date: September 15, 2016
    Inventors: Henrik Oestergaard, Marianne Kjalke, Ole Hvilsted Olsen, Lars Thim, Henning Ralf Stennicke
  • Targeted Delivery of Factor VIII Proteins to Platelets
    Publication number: 20160251409
    Abstract: The invention described herein relates to novel molecules and polypeptides comprising at least one amino acid sequence having significant identity with (homology to) human Factor VIII or biologically active portion(s) thereof, related molecules (such as nucleic acids encoding such polypeptides), compositions (such as pharmaceutical formulations) comprising such polypeptides, and methods of making and using such polypeptides.
    Type: Application
    Filed: May 19, 2016
    Publication date: September 1, 2016
    Inventors: Henrik Oestergaard, Anthony Pusateri, Thomas R. Barnett, Jens Buchardt, Bernd Peschke, Mikael Kofod-Hansen, Magali A. Zundel, Carsten Behrens, Eva H. Norling Olsen, Henning Stennicke
  • Polypeptides having peroxygenase activity and polynucleotides encoding same
    Patent number: 9404093
    Abstract: The present invention relates to isolated polypeptides having peroxygenaseactivity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Grant
    Filed: November 28, 2012
    Date of Patent: August 2, 2016
    Assignee: Novozymes A/S
    Inventors: Sara Landvik, Lars Henrik Oestergaard, Lisbeth Kalum
  • Polypeptides having peroxygenase activity
    Patent number: 9404094
    Abstract: The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. A polynucleotide encoding a peroxygenase was isolated from Myceliophtora hinnulea.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: August 2, 2016
    Assignee: Novozymes A/S
    Inventors: Sara Landvik, Lars Henrik Oestergaard, Lisbeth Kalum
  • Polypeptides having peroxygenase activity and polynucleotides encoding same
    Patent number: 9404133
    Abstract: The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Grant
    Filed: September 10, 2015
    Date of Patent: August 2, 2016
    Assignee: NOVOZYMES A/S
    Inventors: Sara Landvik, Lars Henrik Oestergaard, Lisbeth Kalum
  • Coagulation factor VII polypeptides
    Patent number: 9370583
    Abstract: The present invention relates to modified coagulation Factor VII polypeptides exhibiting increased resistance to antithrombin inactivation and enhanced proteolytic activity. The present invention also relates to polynucleotide constructs encoding such polypeptides, vectors and host cells comprising and expressing such polynucleotides, pharmaceutical compositions, uses and methods of treatment.
    Type: Grant
    Filed: November 9, 2015
    Date of Patent: June 21, 2016
    Assignee: NOVO NORDISK HEALTHCARE AG
    Inventors: Henrik Oestergaard, Prafull S. Gandhi, Ole Hvilsted Olsen, Carsten Behrens, Paul L. DeAngelis, Friedrich Michael Haller
  • Coagulation factor VII polypeptides
    Patent number: 9371370
    Abstract: The present invention relates to modified coagulation Factor VII polypeptides exhibiting increased resistance to antithrombin inactivation and enhanced proteolytic activity. The present invention also relates to polynucleotide constructs encoding such polypeptides, vectors and host cells comprising and expressing such polynucleotides, pharmaceutical compositions, uses and methods of treatment.
    Type: Grant
    Filed: October 15, 2014
    Date of Patent: June 21, 2016
    Assignee: NOVO NORDISK HEALTHCARE AG
    Inventors: Henrik Oestergaard, Prafull S. Gandhi, Ole Hvilsted Olsen
  • COAGULATION FACTOR VII POLYPEPTIDES
    Publication number: 20160120992
    Abstract: The present invention relates to modified coagulation Factor VII polypeptides exhibiting increased resistance to antithrombin inactivation and enhanced proteolytic activity. The present invention also relates to polynucleotide constructs encoding such polypeptides, vectors and host cells comprising and expressing such polynucleotides, pharmaceutical compositions, uses and methods of treatment.
    Type: Application
    Filed: November 9, 2015
    Publication date: May 5, 2016
    Inventors: Henrik Oestergaard, Prafull S. Gandhi, Ole Hvilsted Olsen, Carsten Behrens, Paul L. DeAngelis, Friedrich Michael Haller
  • THROMBIN SENSITIVE COAGULATION FACTOR X MOLECULES
    Publication number: 20160024487
    Abstract: The present invention relates to thrombin sensitive coagulation Factor X (FX), as well as use thereof in medicine. In particular the invention relates to FX molecules comprising 2 to 10 amino acid modifications in the activation peptide N-terminally of the FX “IVGG” motif as well as compositions comprising such molecules and use thereof. Such molecules may be useful in connection with convenient and patient friendly treatment regimens in treatment and prophylaxis of haemophilia.
    Type: Application
    Filed: March 12, 2014
    Publication date: January 28, 2016
    Applicant: NOVO NORDISK A/S
    Inventors: Jens J. Hansen, Jens Breinholt, Jens Buchardt, Kristoffer Winther Balling, Prafull S. Gandhi, Henrik Oestergaard, Grant E. Blouse
  • Polypeptides Having Peroxygenase Activity and Polynucleotides Encoding Same
    Publication number: 20160002683
    Abstract: The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Application
    Filed: September 10, 2015
    Publication date: January 7, 2016
    Applicant: NOVOZYMES A/S
    Inventors: Sara Landvik, Lars Henrik Oestergaard, Lisbeth Kalum
  • Factor VIII Molecules With Reduced VWF Binding
    Publication number: 20150376262
    Abstract: The present invention relates to a recombinant Factor VIII molecule, wherein said molecule has reduced vWF binding capacity, and wherein said molecule is covalently conjugated with at least one side group.
    Type: Application
    Filed: September 11, 2015
    Publication date: December 31, 2015
    Inventors: Bernd Peschke, Mikael Kofod-Hansen, Jens Buchardt, Henning Ralf Stennicke, Henrik Oestergaard, Marianne Kjalke, Eva H. Norling Olsen, Olsen, Jens Jacob Hansen
  • Bleaching of pulp
    Patent number: 9222078
    Abstract: The use of a peroxidase and violuric acid, or a derivative thereof in the bleaching of pulp, such as paper materials, such as paper, linerboard, corrugated paperboard, tissue, towels, corrugated containers and boxes. The peroxidases of the invention are classified as EC 1.11.1.7. The effect of peroxidase is bleaching and de-inking of the pulp, e.g. the paper pulp and the resulting paper material.
    Type: Grant
    Filed: July 1, 2011
    Date of Patent: December 29, 2015
    Assignee: NOVOZYMES A/S
    Inventors: Lisbeth Kalum, Henrik Lund, Lars Henrik Oestergaard, Hanne Lyngby Hoest Pedersen
  • COAGULATION FACTOR VII POLYPEPTIDES
    Publication number: 20150307865
    Abstract: The present invention relates to modified coagulation Factor VII (Factor VII) polypeptides having coagulant activity as well as polynucleotide constructs encoding such polypeptides, vectors and host cells comprising and expressing such polynucleotides, pharmaceutical compositions, uses and methods of treatment.
    Type: Application
    Filed: October 15, 2013
    Publication date: October 29, 2015
    Inventors: Henning R. Stennicke, Ole Hvilsted Olsen, Henrik Oestergaard
  • Polypeptides having peroxygenase activity and polynucleotides encoding same
    Patent number: 9169469
    Abstract: The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Grant
    Filed: November 28, 2012
    Date of Patent: October 27, 2015
    Assignee: Novozymes A/S
    Inventors: Sara Landvik, Lars Henrik Oestergaard, Lisbeth Kalum
  • POLYPEPTIDES HAVING PEROXYGENASE ACTIVITY
    Publication number: 20150275189
    Abstract: The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. A polynucleotide encoding a peroxygenase was isolated from Penicillium chrysogenum.
    Type: Application
    Filed: October 8, 2013
    Publication date: October 1, 2015
    Inventors: Sara Landvik, Lars Henrik Oestergaard, Lisbeth Kalum
  • Polypeptides Having Peroxygenase Activity
    Publication number: 20150267179
    Abstract: The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. A polynucleotide encoding a peroxygenase was isolated from Thielavia hyrcaniae.
    Type: Application
    Filed: October 8, 2013
    Publication date: September 24, 2015
    Inventors: Sara Landvik, Lars Henrik Oestergaard, Lisbeth Kalum