Patents by Inventor Henrik Oestergaard

Henrik Oestergaard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FACTOR VII CONJUGATES
    Publication number: 20150259665
    Abstract: The present invention relates to the conjugation of Factor VII polypeptides with heparosan polymers. The resultant conjugates may be used to deliver Factor VII, for example in the treatment or prevention of bleeding disorders.
    Type: Application
    Filed: October 15, 2013
    Publication date: September 17, 2015
    Inventors: Carsten Behrens, Henrik Oestergaard, Henning Ralf Stennicke
  • POLYPEPTIDES HAVING PEROXYGENASE ACTIVITY
    Publication number: 20150259651
    Abstract: The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. A polynucleotide encoding a peroxygenase was isolated from Thielavia terrestris.
    Type: Application
    Filed: October 8, 2013
    Publication date: September 17, 2015
    Inventors: Sara Landvik, Lars Henrik Oestergaard, Lisbeth Kalum
  • POLYPEPTIDES HAVING PEROXYGENASE ACTIVITY
    Publication number: 20150247130
    Abstract: The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. A polynucleotide encoding a peroxygenase was isolated from Daldinia caldariorum.
    Type: Application
    Filed: October 8, 2013
    Publication date: September 3, 2015
    Applicant: Novozymes A/S
    Inventors: Sara Landvik, Lars Henrik Oestergaard, Lisbeth Kalum
  • Polypeptides Having Peroxygenase Activity
    Publication number: 20150240218
    Abstract: The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. A polynucleotide encoding a peroxygenase was isolated from Myceliophthora fergusii.
    Type: Application
    Filed: October 8, 2013
    Publication date: August 27, 2015
    Inventors: Sara Landvik, Lars Henrik Oestergaard, Lisbeth Kalum
  • LACCASE VARIANTS
    Publication number: 20150240425
    Abstract: The present invention relates to variants of a parent laccase. The present invention also relates to polynucleotides encoding the variant laccases and to nucleic acid constructs, vectors, and host cells comprising the polynucleotides, and methods of using the variant enzymes.
    Type: Application
    Filed: May 11, 2015
    Publication date: August 27, 2015
    Inventors: Lars Henrik Oestergaard, Leonardo De Maria, Miguel Duarte Toscano
  • THERAPEUTIC FACTOR VIII ANTIBODIES
    Publication number: 20150239984
    Abstract: The present invention relates to therapeutic FVIII antibodies. In particular, the present invention relates to FVIII antibodies having the ability to prolong the circulatory half life of FVIII. The present invention furthermore relates to use of such antibodies in treatment and prophylaxis of haemophilia A.
    Type: Application
    Filed: May 12, 2015
    Publication date: August 27, 2015
    Applicant: NOVO NORDISK A/S
    Inventors: Henrik Oestergaard, Ida Hilden, Heidi L. Holmberg, Kasper Lamberth, Jes T. Clausen
  • Polypeptides Having Peroxygenase Activity
    Publication number: 20150232816
    Abstract: The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. A polynucleotide encoding a peroxygenase was isolated from Myceliophtora hinnulea.
    Type: Application
    Filed: October 8, 2013
    Publication date: August 20, 2015
    Inventors: Sara Landvik, Lars Henrik Oestergaard, Lisbeth Kalum
  • Polypeptides Having Peroxygenase Activity
    Publication number: 20150232817
    Abstract: The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. A polynucleotide encoding a peroxygenase was isolated from Pestalotiopsis virgatula.
    Type: Application
    Filed: October 8, 2013
    Publication date: August 20, 2015
    Inventors: Sara Landvik, Lars Henrik Oestergaard, Lisbeth Kalum
  • Polypeptides Having Peroxygenase Activity
    Publication number: 20150218529
    Abstract: The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides. A polynucleotide encoding a peroxygenase was isolated from Pestalotiopsis virgatula.
    Type: Application
    Filed: October 8, 2013
    Publication date: August 6, 2015
    Inventors: Sara Landvik, Lars Henrik Oestergaard, Lisbeth Kalum
  • Therapeutic factor VIII antibodies
    Patent number: 9062115
    Abstract: The present invention relates to therapeutic FVIII antibodies. In particular, the present invention relates to FVIII antibodies having the ability to prolong the circulatory half life of FVIII. The present invention furthermore relates to use of such antibodies in treatment and prophylaxis of haemophilia A.
    Type: Grant
    Filed: September 15, 2011
    Date of Patent: June 23, 2015
    Assignee: Novo Nordisk A/S
    Inventors: Henrik Oestergaard, Ida Hilden, Heidi Lindgreen Holmberg, Kasper Lamberth, Jes Thorn Clausen
  • Laccase variants
    Patent number: 9057040
    Abstract: The present invention relates to variants of a parent laccase. The present invention also relates to polynucleotides encoding the variant laccases and to nucleic acid constructs, vectors, and host cells comprising the polynucleotides, and methods of using the variant enzymes.
    Type: Grant
    Filed: April 16, 2009
    Date of Patent: June 16, 2015
    Assignee: NOVOZYMES A/S
    Inventors: Lars Henrik Oestergaard, Leonardo De Maria, Miguel Duarte Toscano
  • COAGULATION FACTOR VII POLYPEPTIDES
    Publication number: 20150105321
    Abstract: The present invention relates to modified coagulation Factor VII polypeptides exhibiting increased resistance to antithrombin inactivation and enhanced proteolytic activity. The present invention also relates to polynucleotide constructs encoding such polypeptides, vectors and host cells comprising and expressing such polynucleotides, pharmaceutical compositions, uses and methods of treatment.
    Type: Application
    Filed: October 15, 2014
    Publication date: April 16, 2015
    Inventors: Henrik Oestergaard, Prafull S. Gandhi, Ole Hvilsted Olsen
  • FVIIa-sTF complexes exhibiting exosite-mediated super activity
    Publication number: 20150044195
    Abstract: Disclosed are disulphide-linked complexes of a soluble Tissue Factor (sTF) variant of SEQ ID NO:3 comprising the mutation G109C and a Factor VIIa variant of SEQ ID NO. 1, comprising the mutation Q64C and a mutation at position M306 that gives rise to a zymogen-like conformation in the Factor VIIa polypeptide. Said complexes may be used for the treatment of a coagulopathy.
    Type: Application
    Filed: March 15, 2013
    Publication date: February 12, 2015
    Applicant: NOVO NORDISK HEALTHCARE AG
    Inventors: Henrik Oestergaard, Anders Laerke Nielsen, Ole Hvilsted Olsen
  • Polypeptides Having Peroxygenase Activity And Polynucleotides Encoding Same
    Publication number: 20140322768
    Abstract: The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Application
    Filed: November 28, 2012
    Publication date: October 30, 2014
    Inventors: Sara Landvik, Lars Henrik Oestergaard, Lisbeth Kalum
  • Polypeptides Having Peroxygenase Activity And Polynucleotides Encoding Same
    Publication number: 20140322770
    Abstract: The present invention relates to isolated polypeptides having peroxygenaseactivity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Application
    Filed: November 28, 2012
    Publication date: October 30, 2014
    Inventors: Sara Landvik, Lars Henrik Oestergaard, Lisbeth Kalum
  • COLOR MODIFICATION OF TEXTILE
    Publication number: 20140310887
    Abstract: The use of a peroxidase, a source of hydrogen peroxide and a mediator for providing a modified color in the textile is described.
    Type: Application
    Filed: September 7, 2012
    Publication date: October 23, 2014
    Applicant: Novozymes A/S
    Inventors: Yucheng Zhou, Chu Wang, Lisbeth Kalum, Lars Henrik Oestergaard, Wenqi Huang
  • Selective modification of proteins
    Patent number: 8859731
    Abstract: A method of selectively introducing a substituent into a protein proximal to a binding site on the protein for a homing peptide, comprising: (a) contacting the protein with a compound comprising a homing peptide having the ability to bind to the binding site of the protein; and (b) allowing a moiety on the protein proximal to the binding site to react with the compound comprising the homing peptide, thereby to transfer the substituent G onto the protein.
    Type: Grant
    Filed: April 12, 2011
    Date of Patent: October 14, 2014
    Assignee: Novo Nordisk A/S
    Inventors: Mikael Kofod-Hansen, Henning Ralf Stennicke, Soeren Oestergaard, Henrik Oestergaard
  • Polypeptides Having Peroxygenase Activity and Polynucleotides Encoding Same
    Publication number: 20140234918
    Abstract: The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Application
    Filed: August 10, 2012
    Publication date: August 21, 2014
    Applicant: Novozymes A/S
    Inventors: Sara Landvik, Lars Henrik Oestergaard, Lisbeth Kalum
  • Polypeptides Having Peroxygenase Activity and Polynucleotides Encoding Same
    Publication number: 20140170715
    Abstract: The present invention relates to isolated polypeptides having peroxygenase activity, and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Application
    Filed: August 10, 2012
    Publication date: June 19, 2014
    Inventors: Sara Landvik, Lars Henrik Oestergaard, Lisbeth Kalum
  • Coagulation factor VII polypeptides
    Patent number: 8674074
    Abstract: The present invention relates to novel coagulation Factor VII polypeptides, polynucleotide constructs encoding such polypeptides, as well as vectors and host cells comprising and expressing the polynucleotide, pharmaceutical compositions, uses and methods of treatment.
    Type: Grant
    Filed: April 19, 2010
    Date of Patent: March 18, 2014
    Assignee: Novo Nordisk Healthcare AG
    Inventor: Henrik Østergaard