Abstract: A magnetic sensor comprises a magnetic material portion; an excitation portion; and a magnetic detection portion, the magnetic sensor detecting a magnetic field by the magnetic detection portion detecting a detection magnetic field generated due to magnetic moments of the magnetic material portion. The excitation portion is configured to include a conductive material formed into an elongated shape, the magnetic material portion is a soft magnetic film formed on a surface of the conductive material, and the magnetic moments of the magnetic material portion are oriented along circumferential directions of the conductive material orthogonal to a longitudinal direction of the conductive material such that the magnetic moments directed to one of the circumferential directions and the magnetic moments direction in another circumferential direction opposite to the one circumferential direction are distributed in substantially equal amounts.

Abstract: As an antitumor drug which is excellent in terms of antitumor effect and safety and has an excellent therapeutic effect, there is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an anti-HER2 antibody via a linker having a structure represented by the formula: L1-L2-LP-NH—(CH2)n1-La-Lb-Lc or -L1-L2-LP- wherein the anti-HER2 antibody is connected to the terminal L1, and the antitumor compound is connected to the terminal Lc or LP with the nitrogen atom of the amino group at position 1 as the connecting position.

Abstract: Pulsating current (ripple) is generated in a zero-phase current to increase a loss. A motor control system includes an inverter which drives a motor which includes windings separately wound around each phase and an inverter control unit which generates an output voltage pulse corresponding to each phase to control the inverter on the basis of a torque command value and a rotor position of the motor. The inverter control unit divides the output voltage pulse of at least one phase of the output voltage pulses into several pulses during one period of the output voltage pulse such that a zero-phase voltage of only one of positive and negative polarities is output several times from the motor in the one pulse period.

Abstract: Pulsating current (ripple) is generated in a zero-phase current to increase a loss. A motor control system includes an inverter which drives a motor which includes windings separately wound around each phase and an inverter control unit which generates an output voltage pulse corresponding to each phase to control the inverter on the basis of a torque command value and a rotor position of the motor. The inverter control unit divides the output voltage pulse of at least one phase of the output voltage pulses into several pulses during one period of the output voltage pulse such that a zero-phase voltage of only one of positive and negative polarities is output several times from the motor in the one pulse period.

Abstract: A measurement device includes a sensing portion and a measuring portion. The sensing portion contains at least a fluorescent material whose emitting of fluorescent light ceases due to an action of a radioactive beam. The measuring portion measures a radiation quantity of the radioactive beam, with which the sensing portion is irradiated, based on an amount of decrease in the intensity of the fluorescent light emitted by the fluorescent material contained in the sensing portion when the radioactive beam acts on at least a portion of the fluorescent material. The fluorescent light is emitted due to irradiation of the fluorescent material by an excitation source.

Abstract: As an antitumor drug which is excellent in terms of antitumor effect and safety, there is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an antibody via a linker having a structure represented by the following formula: -L1-L2-LP-NH—(CH2)n1-La-Lb-Lc- wherein the antibody is connected to the terminal of L1, and the antitumor compound is connected to the terminal of Lc with the nitrogen atom of the amino group at position 1 as a connecting position.

Abstract: An electric power conversion apparatus includes a channel case in which a cooling water channel is formed; a double side cooling semiconductor module that has an upper and lower arms series circuit of an inverter circuit; a capacitor module; a direct current connector; and an alternate current connector. The semiconductor module includes first and second heat dissipation metals whose outer surfaces are heat dissipation surfaces, the upper and lower arms series circuit is disposed tightly between the first heat dissipation metal and the second heat dissipation metal, and the semiconductor module further includes a direct current positive terminal, a direct current negative terminal, and an alternate current terminal which protrude to outside. The channel case is provided with the cooling water channel which extends from a cooling water inlet to a cooling water outlet, and a first opening which opens into the cooling water channel.

Abstract: A motor can be controlled in a user-friendly manner so that a phase current based on an input command torque command value is caused to flow to at least one among U-phase, V-phase, and W-phase windings of the motor, so that a predetermined in-phase current is superimposed on the phase current and caused to flow to at least one among the windings. The motor is controlled such that energization to one winding corresponding to a predetermined energization stop phase is stopped, for example, so that energization to the U-phase winding is stopped, and so that a V-phase current, a W-phase current and an in-phase current are caused to flow to each winding corresponding to a phase other than the energization stop phase, for example, so that the V-phase current, the W-phase current and the in-phase current are caused to flow to the V-phase winding and the W-phase winding.

Abstract: A six-wire three-phase motor that can realize both of increasing an output and reducing a torque ripple is provided. A six-wire three-phase motor is a six-wire three-phase motor including: a stator including a winding wire wound independently between phases; and a rotor including a plurality of magnets in a circumferential direction, wherein the stator or the rotor is configured in such a manner that a third harmonic current component in a motor current of when an overmodulation voltage based on a PWM signal is applied becomes higher than a third harmonic current component in a motor current of when a sinusoidal modulation voltage based on the PWM signal is applied.

Abstract: As an antitumor drug which is excellent in terms of antitumor effect and safety and has an excellent therapeutic effect, there is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an anti-HER2 antibody via a linker having a structure represented by the following formula: -L1-L2-LP-NH—(CH2)n1-La-(CH2)n2-C(?O)— wherein the anti-HER2 antibody is connected to the terminal L1, and the antitumor compound is connected to the carbonyl group of the —(CH2)n2-C(?O)— moiety with the nitrogen atom of the amino group at position 1 as the connecting position.

Abstract: A measuring device includes at least two magnetic sensors capable of selectively measuring a magnitude of a component in a specific direction of a magnetic field. The measuring device repeatedly acquires, at a plurality of timings, a measurement value indicating the magnitude of the magnetic field detected by each of the at least two magnetic sensors. The measuring device identifies the measurement value having the largest absolute value, from among at least two measurement values acquired at a specific timing from each of the at least two magnetic sensors. The measuring device identifies a first magnetic sensor that has detected the identified measurement value having the largest absolute value. The measuring device identifies, based on a time change in the acquired measurement value, a distance in an orthogonal direction that is orthogonal to the specific direction, between an object to be measured and the identified first magnetic sensor.

Abstract: As an antitumor drug which is excellent in terms of antitumor effect and safety, there is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula is conjugated to an antibody via a linker having a structure represented by the following formula: -L1-L2-LF-NH—(CH2)n1-La-Lb-Lc- wherein the antibody is connected to the terminal of L1, and the antitumor compound is connected to the terminal of Lc with the nitrogen atom of the amino group at position 1 as a connecting position.

Abstract: As an antitumor drug which is excellent in terms of antitumor effect and safety, there is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula (I) is conjugated to an antibody via a linker having a structure represented by the following formula: -L1-L2-LP-NH—(CH2)n1-La-Lb-Lc- or -L1-L2-LP- wherein the antibody is connected to the terminal of L1, the antitumor compound is connected to the terminal of Lc or LP, and any one or two or more of linkers of L1, L2, and LP has a hydrophilic structure.

Abstract: In a magnetic material detection device comprising: at least two magnetic sensors; and a control device detecting a magnetic material by using output values of the magnetic sensors, the magnetic sensors are arranged at an interval of a predetermined distance from each other such that a subject is located outside a space therebetween, and the control device detects the magnetic material by comparing time change amounts of output values of the magnetic sensors resulting from a change in relative position between the subject and each of the magnetic sensors, with utilizing that an absolute value of the time change amount becomes larger in one of the magnetic sensors close to the subject as compared to another of the magnetic sensors far from the subject.

Abstract: A boron neutron capture therapy system has a neutron beam irradiation device, a patient restraint/placement portion, a three-dimensional diagnostic device, an irradiation table, a position adjustment mechanism, and a control unit. The boron neutron capture therapy system performs position determination with a sufficient degree of accuracy at the time of the boron neutron capture therapy. Further, the control unit, using the movement of the irradiation table, performs collision avoidance processing that changes the movement of the irradiation table before the patient restrained on the patient restraint/placement portion receives injury by colliding with the irradiation port, and thus, collision between the patient and the irradiation port can be avoided.

Abstract: A magnetic sensor comprises a magnetic material portion; an excitation portion; and a magnetic detection portion, the magnetic sensor detecting a magnetic field by the magnetic detection portion detecting a detection magnetic field generated due to magnetic moments of the magnetic material portion. The excitation portion is configured to include a conductive material formed into an elongated shape, the magnetic material portion is a soft magnetic film formed on a surface of the conductive material, and the magnetic moments of the magnetic material portion are oriented along circumferential directions of the conductive material orthogonal to a longitudinal direction of the conductive material such that the magnetic moments directed to one of the circumferential directions and the magnetic moments direction in another circumferential direction opposite to the one circumferential direction are distributed in substantially equal amounts.

Abstract: An electric power conversion apparatus includes a channel case in which a cooling water channel is formed; a double side cooling semiconductor module that has an upper and lower arms series circuit of an inverter circuit; a capacitor module; a direct current connector; and an alternate current connector. The semiconductor module includes first and second heat dissipation metals whose outer surfaces are heat dissipation surfaces, the upper and lower arms series circuit is disposed tightly between the first heat dissipation metal and the second heat dissipation metal, and the semiconductor module further includes a direct current positive terminal, a direct current negative terminal, and an alternate current terminal which protrude to outside. The channel case is provided with the cooling water channel which extends from a cooling water inlet to a cooling water outlet, and a first opening which opens into the cooling water channel.

Abstract: A measurement device includes a sensing portion and a measuring portion. The sensing portion contains at least a fluorescent material whose emitting of fluorescent light ceases due to an action of a radioactive beam. The measuring portion measures a radiation quantity of the radioactive beam, with which the sensing portion is irradiated, based on an amount of decrease in the intensity of the fluorescent light emitted by the fluorescent material contained in the sensing portion when the radioactive beam acts on at least a portion of the fluorescent material. The fluorescent light is emitted due to irradiation of the fluorescent material by an excitation source.

Abstract: An electric power conversion apparatus includes a channel case in which a cooling water channel is formed; a double side cooling semiconductor module that has an upper and lower arms series circuit of an inverter circuit; a capacitor module; a direct current connector; and an alternate current connector. The semiconductor module includes first and second heat dissipation metals whose outer surfaces are heat dissipation surfaces, the upper and lower arms series circuit is disposed tightly between the first heat dissipation metal and the second heat dissipation metal, and the semiconductor module further includes a direct current positive terminal, a direct current negative terminal, and an alternate current terminal which protrude to outside. The channel case is provided with the cooling water channel which extends from a cooling water inlet to a cooling water outlet, and a first opening which opens into the cooling water channel.

Abstract: In a case where a switching element of an inverter does not operate properly due to failure or the like, a three-phase short circuit cannot be made, and an induced voltage cannot be suppressed. An induced voltage suppression device is electrically connected to the three-phase wiring between the power converter and the motor, in parallel to the power converter. A rectification circuit including a three-phase diode bridge circuit. A DC voltage source including a capacitor. A voltage detection circuit detects a voltage of both ends of the DC voltage source. In a short circuit, when a transistor of the voltage detection circuit is turned on, transistors are turned on to perform three-phase short-circuit operation to suppress an induced voltage of the motor. Since the induced voltage suppression device secures a DC voltage by the induced voltage of the motor as a drive source in a self-excited manner, it is possible to suppress the induced voltage even when an abnormality occurs in the power converter.