Abstract: An optical fiber holder includes a holder main body, a V-groove which is formed on an upper surface of the holder main body and accommodates a first optical fiber, a recessed groove which is formed on a same straight line with the V-groove and accommodates a second optical fiber having a coating portion with a larger outer diameter than the first optical fiber, and an abutting portion which is provided on an end portion of the recessed groove on an opposite side to the V-groove and includes an opening portion which has a smaller width than the recessed groove. When the second optical fiber is accommodated in the recessed groove, a fiber core wire of the second optical fiber protrudes to an outside via the opening portion and an end portion of the coating portion of the second optical fiber abuts on the abutting portion.

Abstract: An optical fiber cutting apparatus includes a body portion on which an optical fiber is mounted, a cover member that is rotatably connected to the body portion and fixes the optical fiber between the body portion and the cover member by rotating toward the body portion, a blade member configured to form a flaw on a glass fiber portion of the optical fiber which is fixed, and a holding member mounted on the body portion, the holding member configured to hold the blade member. The cover member presses the holding member and thereby the blade member imparts an arc movement to form the flaw on the glass fiber portion.

Abstract: An optical fiber fusion splicer includes optical fiber holders that hold optical fibers. Each optical fiber holder includes a base, a cover, and a connecting portion. The base includes a setting table on which an optical fiber F is placed so as to be oriented in the longitudinal direction of the base. The cover has pressing members that press the optical fiber F placed on the setting table against the setting table. The connecting portion joins the cover to the base such that the cover is openable away from and closeable over the base and movable in the longitudinal direction of the base.

Abstract: The purpose of the present invention is to provide an osteogenesis promoter for directly promoting osteogenesis by osteoblasts, and an agent for preventing and treating bone disease. The present invention is characterized in that a binding inhibitor substance of semaphorin 4D and plexin B1 is used. For the binding inhibitor substance, suitable examples include anti-semaphorin 4D antibody, anti-plexin B1 antibody, and protein comprising the extracellular domain of plexin B1.

Abstract: An optical fiber fusion splicer includes a base having a fiber groove for containing an optical fiber, a fiber clamp for pressing the optical fiber contained in the fiber groove against the base and load changing means for changing a load for the fiber clamp to press the optical fiber.

Abstract: A method of fusion-splicing includes attaching a stab to a stub cap having a non-axisymmetric structure, positioning an embedded optical fiber to a fusion splicing working part by fixing the stub cap thereto; positioning an outside optical fiber to the fusion splicing working part; fusion-splicing the embedded optical fiber and the outside optical fiber; repositioning the embedded optical fiber to a reinforcing working part by fixing the stub cap thereto and repositioning the outside optical fiber to the reinforcing working part such that a relative positional relationship between the embedded optical fiber and the outside optical fiber becomes the same as that at the fusion splicing working part; and reinforcing a spliced portion between the embedded optical fiber and the outside optical fiber while a tension is applied to the embedded optical fiber and the outside optical fiber.

Abstract: An optical fiber reinforcing heating device has a base part, to which a first lid part for covering a sleeve accommodation groove for containing a fiber reinforcement sleeve covering a fusion-splicing part of optical fibers is attached so as to be openable and closable. A pair of fiber holders for holding and securing the optical fibers are disposed on both end sides of the first lid part. Each fiber holder has a second lid part which is attached to a fiber container so as to be openable and closable and presses the optical fiber against the fiber container. A switch lever which is movable longitudinally of the sleeve accommodation groove is disposed on the upper face of the second lid part built in with a pin adapted to move in conjunction with the switch lever. A joint hole adapted to engage the pin is formed within the first lid part.

Abstract: An optical fiber reinforcing heating device 6A is equipped with a base part 12, while the base part 12 is provided with a sleeve accommodation groove that contains a fiber reinforcement sleeve and a heater having a U-shaped cross section, which heats the fiber reinforcement sleeve. A pair of fiber holders 19 that holds and clamps fusion-spliced optical fibers 3 are disposed on both end sides of the sleeve accommodation groove. A lid part 23 that covers the fiber accommodation groove 13 is attached openably and closably to the base part 12 through a rotary axis. A protector 24 for windbreak and heat insulation is joined to the lid part 23 through a rotary axis 25. The protector 24 is a member for preventing winds from entering the sleeve accommodation groove from a gap between a side wall of the base part 12 and the lid part 23.

Abstract: The purpose of the present invention is to provide an osteogenesis promoter for directly promoting osteogenesis by osteoblasts, and an agent for preventing and treating bone disease. The present invention is characterized in that a binding inhibitor substance of semaphorin 4D and plexin B1 is used. For the binding inhibitor substance, suitable examples include anti-semaphorin 4D antibody, anti-plexin B1 antibody, and protein comprising the extracellular domain of plexin B1.

Abstract: An optical fiber fusion splicer includes a base having a fiber groove for containing an optical fiber, a fiber clamp for pressing the optical fiber contained in the fiber groove against the base and load changing means for changing a load for the fiber clamp to press the optical fiber.

Abstract: An optical fiber reinforcing heating device 6A is equipped with a base part 12, while the base part 12 is provided with a sleeve accommodation groove that contains a fiber reinforcement sleeve and a heater having a U-shaped cross section, which heats the fiber reinforcement sleeve. A pair of fiber holders 19 that holds and clamps fusion-spliced optical fibers 3 are disposed on both end sides of the sleeve accommodation groove. A lid part 23 that covers the fiber accommodation groove 13 is attached openably and closably to the base part 12 through a rotary axis. A protector 24 for windbreak and heat insulation is joined to the lid part 23 through a rotary axis 25. The protector 24 is a member for preventing winds from entering the sleeve accommodation groove from a gap between a side wall of the base part 12 and the lid part 23.

Abstract: An optical fiber fusion-splicing device is equipped with a fusing unit disposed on a housing, which fuses optical fibers F to each other, and a windproof cover that prevents winds from entering the fusing unit. The windproof cover is provided with a blocking elastic body arranged so as to block, in cooperation with a blocking elastic body of the housing, an inlet for introducing the optical fiber F into the fusing unit, a bias spring that biases the blocking elastic body toward the blocking elastic body, and a transmission member that transmits a biasing force of the bias spring to the blocking elastic body.

Abstract: A method of fusion-splicing includes attaching a stab to a stub cap having a non-axisymmetric structure, positioning an embedded optical fiber to a fusion splicing working part by fixing the stub cap thereto; positioning an outside optical fiber to the fusion splicing working part; fusion-splicing the embedded optical fiber and the outside optical fiber; repositioning the embedded optical fiber to a reinforcing working part by fixing the stub cap thereto and repositioning the outside optical fiber to the reinforcing working part such that a relative positional relationship between the embedded optical fiber and the outside optical fiber becomes the same as that at the fusion splicing working part; and reinforcing a spliced portion between the embedded optical fiber and the outside optical fiber while a tension is applied to the embedded optical fiber and the outside optical fiber.

Abstract: An optical fiber fusion splicer includes optical fiber holders that hold optical fibers. Each optical fiber holder includes a base, a cover, and a connecting portion. The base includes a setting table on which an optical fiber F is placed so as to be oriented in the longitudinal direction of the base. The cover has pressing members that press the optical fiber F placed on the setting table against the setting table. The connecting portion joins the cover to the base such that the cover is openable away from and closeable over the base and movable in the longitudinal direction of the base.

Abstract: An optical fiber reinforcing heating device has a base part, to which a first lid part for covering a sleeve accommodation groove for containing a fiber reinforcement sleeve covering a fusion-splicing part of optical fibers is attached so as to be openable and closable. A pair of fiber holders for holding and securing the optical fibers are disposed on both end sides of the first lid part. Each fiber holder has a second lid part which is attached to a fiber container so as to be openable and closable and presses the optical fiber against the fiber container. A switch lever which is movable longitudinally of the sleeve accommodation groove is disposed on the upper face of the second lid part built in with a pin adapted to move in conjunction with the switch lever. A joint hole adapted to engage the pin is formed within the first lid part.

Abstract: Input data (1A) having an integral multiple of 8 bits is divided into symbols in units of b bits (b is an integer of 5 to 7) in a register file 10, an error detecting code is added in an error detection calculation circuit 20, and then encoding (such as Reed Solomon (RS) encoding) having an error correction capability of two or more symbols is performed in a parity calculation circuit 30 to record the data in a storage 40. In the reproduction, error correction in units of symbols is performed to reproduced data from the storage 40 in an error correction circuit 70, error detection processing is performed in an error detection calculation circuit 80, and then data having the integral multiple of 8 bits is recovered in a register file 90 to output the same. By this means, it is possible to provide a storage system with high reliability to a soft error that occurs in a storage such as semiconductor memory.

Abstract: [Problems] To provide a modulator for signaling of TLR [Means for solving the problems] A medicament containing cathepsin inhibitor such as monosodium (2S,3S)-3-[[(1S)-1-isobutoxymethyl-3-methylbutyl]carbamoyl]oxirane-2-carboxylate as a active ingredient is used as a modulator for signaling of TLR, a therapeutic agent for treating diseases associated with TLR signaling, a therapeutic agent for treating diseases associated with induction of Th17 cells, a therapeutic agent for treating diseases associated with production of IL-6, IL-12, IL-17, or IL-23, or a therapeutic agent for treating systemic lupus erythematosus, lupus nephritis, crohn's disease, psoriasis, or acute disseminated encephalomyelitis.

Abstract: A reclining device capable of controlling angles of a seat back of a vehicle is provided. A ratchet plate is superposed on a base plate such that the ratchet plate is rotatable relative to the base plate. An operation shaft is rotatably disposed on the rotation center axis of the ratchet plate. A circular concavity is formed on a surface of the ratchet plate opposed to the base plate around the operation shaft. Inside teeth are provided on an inner circumferential wall surface of the concavity. Pawls having outside teeth on their front end surfaces are disposed on the concavity, and the outside teeth of the pawls engage with and disengaging from the inside teeth in the radial direction of a teeth end circle. Guide projections provided on the base plate slidingly guide the pawls in the radial direction. A cam disposed in a space on the side of rear end surfaces of the pawls is rotatable with the operation shaft.