Abstract: An information processing apparatus includes: a parameter estimation unit that estimates, as parameters indicating a temporal change in interest of a user, a first parameter, a second parameter, and a third parameter based on data including a past behavior of the user and an evaluation value of the behavior, the first parameter being a parameter indicating inherent constant interest of the user, the second parameter being a parameter indicating an effect that the user is influenced by a past behavior and is attracted to a behavior option, and the third parameter being a parameter indicating an effect that the user loses interest due to boredom by a past behavior; a social welfare calculation unit that calculates a value indicating social welfare of the user based on the estimated parameters; and an optimum behavior selection unit that selects an optimum behavior of the user based on the calculated value indicating social welfare and outputs data indicating the selected optimum behavior.

Abstract: An image forming apparatus to which a toner container is detachably mountable includes a mounting portion to which the toner container is detachably mountable and which includes a receiving port for receiving toner supplied from the toner container, a passage for permitting passing of the toner received through the receiving port and provided with a through hole, and a filter portion provided so as to cover the through hole and for permitting passing of air; and an accommodating portion configured to accommodate the toner received through the receiving port. At least a part of the through hole overlaps with the receiving port as viewed in a horizontal direction perpendicular to a direction of gravitation.

Abstract: An electromagnetic relay includes a case, a fixed terminal, and a female screw member. The fixed terminal includes an external connecting portion. The external connecting portion has a screw insertion hole, exposed to the outside from the case, and configured to be screwed to an external terminal. The female screw member is prevented from rotating by the case. The case includes a held portion that is held between the external connecting portion of the fixed terminal and the female screw member in a direction of penetration of the screw insertion hole, the direction of penetration including a first direction from the external connecting portion toward the female screw member and a second direction from the female screw member toward the external connecting portion.

Abstract: A developing device includes an accommodating portion for accommodating toner, a developing roller and a stirring member. The developing device is for use with an image forming apparatus and detachably mounts a replenishing container for replenishing the toner. The accommodating portion includes a receiving opening through which the toner replenished from the accommodating portion is received in the accommodating portion, the receiving opening being provide on a first end side of the accommodating portion with respect to a rotational axis direction of the developing roller. An opening area of the receiving opening when the developing device is viewed in the rotational direction is wider than the opening area of the receiving opening when viewed in a direction perpendicular to the rotational axis direction.

Abstract: An image processing device is communicatively connected to a terminal device. An operation panel accepts an operation from a user. A communication unit has a plurality of antennas and is used to communicate with the terminal device. A controller performs control according to direction information representing a direction of the terminal device in relation to the image processing device, acquired based on a radio wave transmitted between the terminal device and the communication unit. The communication unit is provided within a range corresponding to the operation panel, in a left-right direction as viewed from a front face side where the operation panel can be operated, of side faces of the image processing device.

Abstract: A distance information acquisition unit acquires distance information representing a distance between a terminal device and an image processing device, based on a radio wave arriving from the terminal device. A direction information acquisition unit acquires direction information representing a direction of the terminal device in relation to the image processing device, based on the radio wave arriving from the terminal device. A controller performs processing to perform image processing, based on the distance information and the direction information. The controller performs processing to perform image processing, when a position of the terminal device is within a predetermined range in relation to the image processing device and a rate of change in at least one of the distance from the terminal device and the direction of the terminal device is equal to or lower than a threshold.

Abstract: An image forming apparatus includes a first unit including an image bearing member and a second unit. The second unit includes a developing roller to supply the toner to the image bearing member, a mounting portion in which the replenishing container is dismountably mounted and an accommodating portion to accommodate the toner replenished from the replenishing container. The second unit is movable between a first position where the developing roller contacts the image bearing member and a second position where the developing roller separates from the image bearing member. When a moving direction in which the second unit moves from the first position toward the second position is defined as a separating direction, the second unit is urged in the separating direction by a force which the mounting portion receives from the replenishing container when the replenishing container is mounted to the mounting portion.

Abstract: The present invention aims to provide a prophylactic and/or therapeutic agent for diabetes that is highly effective on diabetes developed as a side effect from immune checkpoint inhibitors and has a certain effect on many patients. The present invention is a therapeutic agent for diabetes comprising mesenchymal stem cells. The prophylactic and/or therapeutic agents for diabetes of the present invention are suitably used particularly for diabetes caused by immune checkpoint inhibitors and diabetes caused by anti-PD-1 antibody or anti-PD-L1 antibody.

Abstract: An object of the present invention is to provide novel mesenchymal stem cells demonstrating superior therapeutic effects against various diseases, a novel pharmaceutical composition containing these mesenchymal stem cells, and a method for preparing the same. The present invention relates to ROR1-positive mesenchymal stem cells. The ROR1-positive mesenchymal stem cells are preferably positive for CD29, CD73, CD90, CD105 and CD166 and are derived from umbilical cord or adipose tissue.

Abstract: An object of the present invention is to provide novel mesenchymal stem cells demonstrating superior therapeutic effects for various diseases, a novel pharmaceutical composition containing the mesenchymal stem cells, and methods for preparing these. The present invention provides mesenchymal stem cells expressing at least one cell surface marker selected from the group consisting of CD201, CD46, CD56, CD147 and CD165. The mesenchymal stem cells expressing such a specific marker are positive for CD29, CD73, CD90, CD105 and CD166, and maintain an undifferentiated state.

Abstract: A hydraulic device is provided. Working fluid stored in a fluid storage portion is supplied by a fluid supply portion to a power output portion. The fluid supply portion is driven by a brushless motor. A bypass flow path portion can be switched between a first state of supplying the working fluid from the fluid supply portion to the fluid storage portion and a second state of blocking the fluid supply portion from the fluid storage portion. A control to switch the bypass flow path portion from the first state to the second state after the brushless motor is started and a control to switch the bypass flow path portion from the second state to the first state when the brushless motor is stopped is performed. Backflow of the working fluid from the power output portion to the bypass flow path portion is prevented by a backflow prevention valve.

Abstract: A hydraulic unit is provided with: a manifold which forms a hydraulic circuit; a tank which is joined to the manifold; and a hydraulic pump which suctions hydraulic fluid in the tank and supplies the hydraulic fluid to the manifold, wherein the base end portion of a suction strainer is fitted into the hydraulic pump, and the suction strainer has such a shape that the base end portion of the suction strainer is not separated from the hydraulic pump in a state where the leading end portion of the suction strainer is in contact with the tank and an opening through which the hydraulic fluid is introduced from the tank is provided at the leading end portion.

Abstract: A hydraulic device is provided. Working fluid stored in a fluid storage portion is supplied by a fluid supply portion to a power output portion. The fluid supply portion is driven by a brushless motor. A bypass flow path portion can be switched between a first state of supplying the working fluid from the fluid supply portion to the fluid storage portion and a second state of blocking the fluid supply portion from the fluid storage portion. A control to switch the bypass flow path portion from the first state to the second state after the brushless motor is started and a control to switch the bypass flow path portion from the second state to the first state when the brushless motor is stopped is performed. Backflow of the working fluid from the power output portion to the bypass flow path portion is prevented by a backflow prevention valve.

Abstract: The purpose of the present invention is to provide a therapeutic agent for dilated cardiomyopathy disease which produces excellent effects in the treatment of dilated cardiomyopathy (DCM) and provides a given benefit to a large number of patients. The present invention is a therapeutic agent for dilated cardiomyopathy comprising at least one selected from the group consisting of mesenchymal stem cell and microparticles derived from the mesenchymal stem cell. It is preferable that the mesenchymal stem cell is a cell having the ability to contain or secrete microparticles, that the microparticles have an average particle size of 1000 nm or less, and that they are exosomes.

Abstract: The purpose of the present invention is to provide the following: novel mesenchymal stem cells having an excellent therapeutic effect on various diseases, particularly diseases associated with fibrosis; and a pharmaceutical composition containing such mesenchymal stem cells. The present invention is a therapeutic agent for fibrosis that contains ROR1-positive mesenchymal stem cells and/or a culture supernatant thereof and that is for preventing or treating a disease associated with fibrosis. The mesenchymal stem cells are CD29-, CD73-, CD90-, CD105-, and CD166-positive and are preferably derived from the umbilical cord or fat. In addition, the abovementioned disease associated with fibrosis is preferably a liver disease, a lung disease, a kidney disease, or a heart disease.

Abstract: A hydraulic unit is provided with: a manifold which forms a hydraulic circuit; a tank which is joined to the manifold; and a hydraulic pump which suctions hydraulic fluid in the tank and supplies the hydraulic fluid to the manifold, wherein the base end portion of a suction strainer is fitted into the hydraulic pump, and the suction strainer has such a shape that the base end portion of the suction strainer is not separated from the hydraulic pump in a state where the leading end portion of the suction strainer is in contact with the tank and an opening through which the hydraulic fluid is introduced from the tank is provided at the leading end portion.

Abstract: An object of the present invention is to provide novel mesenchymal stem cells demonstrating superior therapeutic effects for various diseases, a novel pharmaceutical composition containing the mesenchymal stem cells, and methods for preparing these. The present invention provides mesenchymal stem cells expressing at least one cell surface marker selected from the group consisting of CD201, CD46, CD56, CD147 and CD165. The mesenchymal stem cells expressing such a specific marker are positive for CD29, CD73, CD90, CD105 and CD166, and maintain an undifferentiated state.

Abstract: An object of the present invention is to provide novel mesenchymal stem cells demonstrating superior therapeutic effects against various diseases, a novel pharmaceutical composition containing these mesenchymal stem cells, and a method for preparing the same. The present invention relates to ROR1-positive mesenchymal stem cells. The ROR1-positive mesenchymal stem cells are preferably positive for CD29, CD73, CD90, CD105 and CD166 and are derived from umbilical cord or adipose tissue.

Abstract: The present invention aims to provide a mesenchymal stem cell culture medium suitable for culturing umbilical cord mesenchymal stem cells in particular, among the mesenchymal stem cells. The present invention is of a mesenchymal stem cell culture medium comprising at least 2 kinds of components selected from the group consisting of a PTEN inhibitor, a p53 inhibitor, a p38 inhibitor, an Wnt signal activator and a ROCK inhibitor as well as basal medium for culturing animal cells.

Abstract: The invention relates to an internal body observation device which includes an ordinary observation light source, an ordinary observation irradiation optical system, a special observation light source, a special observation irradiation optical system, an observation optical system for transmitting the light from an observation target, a detection means configured to detect the light transmitted from the observation optical system as a detection signal, and a processing unit for separating the detection signal in the respective light sources and making the detection signal into images, wherein the light from any one of the ordinary observation light source and the special observation light source is modulated, and the modulated light can be radiated to the observation target together with the light from the other light source, and the detection signal detected by the detection means is separated by the processing unit based on the frequency of the modulation.