Abstract: This invention has an LED voice controller with an LED luminous mode control unit and a voice forwarding unit, converting a voice control instruction picked up from a user into an audio signal for output; a first transfer unit, transferring the audio signal output by the voice forwarding unit; and a conversion unit, converting the audio signal into a regulation instruction recognizable by the LED luminous mode control unit for output to the first transfer unit, which the LED luminous mode control unit outputs a control signal for LED regulation after receiving the regulation instruction sent by the first transfer unit; or the voice forwarding unit outputs the regulation instruction to the LED luminous mode control unit after receiving the regulation instruction sent by the first transfer unit, and the LED luminous mode control unit outputs the control signal for LED regulation after receiving the regulation instruction.

Abstract: Disclosed herein are gear shifters to reverse an output shaft rotation and a method for using the same. A gear shifter in accordance with the present invention may include a housing, an input shaft, an output shaft and an idler shaft. The input shaft may have input gears, the output shaft may have output gears and the idler shaft may have idler gears. The output shaft may be slidably coupled with the input shaft and the idler shaft to rotate in a first direction in a first position and in a second opposite direction in a second position. A method of reversing an output shaft direction using a gear shifter may include the steps of pushing the gear shifter in a first direction to rotate the output shaft in a first direction and pushing the gear shifter in a second direction to rotate the output shaft in a second direction.

Abstract: A manufacturing method of a semiconductor device including the following steps is provided. A substrate having a device structure and a first interconnection structure on a front side is provided. A first annealing process is performed in an atmosphere of pure hydrogen at a first temperature. A second interconnection structure is formed on a back side of the substrate. A second annealing process is performed in an atmosphere of gas mixture including hydrogen at a second temperature.

Abstract: The present disclosure relates to a novel crystalline form of Galunisertib, processes for preparation and use thereof. The present disclosure also relates to a pharmaceutical composition comprises the novel crystalline form of Galunisertib and use of the novel crystalline form of Galunisertib and pharmaceutical composition for preparing drugs treating disease. The crystalline form of the present disclosure has good stability, solubility and hygroscopicity, which has significant value for future drug optimization and development.

Abstract: Provided are van der Waals (VDW) films comprising one or more transition metal chalcogenide (TMD) films. Also provided are methods of making VDW films. The methods are based on transfer of monolayer TMD films under vacuum, for example, using a handle layer. Also provided are apparatuses and devices comprising one or more VDW film.

Abstract: The present disclosure relates to a novel crystalline form of Galunisertib, processes for preparation and use thereof. The present disclosure also relates to a pharmaceutical composition comprises the novel crystalline form of Galunisertib and use of the novel crystalline form of Galunisertib and pharmaceutical composition for preparing drugs treating disease. The crystalline form of the present disclosure has good stability, solubility and hygroscopicity, which has significant value for future drug optimization and development.

Abstract: Disclosed herein are gear shifters to reverse an output shaft rotation and a method for using the same. A gear shifter in accordance with the present invention may include a housing, an input shaft, an output shaft and an idler shaft. The input shaft may have input gears, the output shaft may have output gears and the idler shaft may have idler gears. The output shaft may be slidably coupled with the input shaft and the idler shaft to rotate in a first direction in a first position and in a second opposite direction in a second position. A method of reversing an output shaft direction using a gear shifter may include the steps of pushing the gear shifter in a first direction to rotate the output shaft in a first direction and pushing the gear shifter in a second direction to rotate the output shaft in a second direction.

Abstract: A manufacturing method of a semiconductor device including the following steps is provided. A substrate having a device structure and a first interconnection structure on a front side is provided. A first annealing process is performed in an atmosphere of pure hydrogen at a first temperature. A second interconnection structure is formed on a back side of the substrate. A second annealing process is performed in an atmosphere of gas mixture including hydrogen at a second temperature.

Abstract: The present disclosure relates to a novel crystalline form of Galunisertib, processes for preparation and use thereof. The present disclosure also relates to a pharmaceutical composition comprises the novel crystalline form of Galunisertib and use of the novel crystalline form of Galunisertib and pharmaceutical composition for preparing drugs treating disease. The crystalline form of the present disclosure has good stability, solubility and hygroscopicity, which has significant value for future drug optimization and development.

Abstract: An air outlet for controlling airflow in a vehicle includes a housing having an air inlet and an air outlet, with first and second walls between the air inlet and the air outlet wherein the first wall is spaced from the second wall, an airfoil located within the housing, and a handle moveably mounted to the airfoil by a coupling.

Abstract: Apparatuses comprising a substrate; a monolayer graphene film disposed on at least a portion of the substrate; and a single-layer transition metal dichalcogenide (TMD) disposed only on the substrate and lateral edges of the monolayer graphene film, methods of making the apparatuses, and devices comprising one or more of the apparatuses. The apparatuses have a one-dimensional ohmic edge contact between the monolayer graphene and monolayer semiconducting TMDs.

Abstract: A three-dimensional (3D) memory structure and a manufacturing method thereof are provided. The method includes the following steps. A 3D memory unit is formed on a first region of a substrate. A first insulation layer is formed on the first region and a second region of the substrate. A first planarization process is performed to the first insulation layer. The top surface of the first insulation layer on the first region and the top surface of the first insulation layer on the second region are coplanar after the first planarization process. A peripheral circuit is formed on the second region after the first planarization process. The influence of the process for forming the 3D memory unit on the peripheral circuit may be avoided. The manufacturing yield, the electrical performance, and the reliability of the 3D memory structure may be enhanced accordingly.

Abstract: The present invention provides a mutant with enhanced secretion of L-asparaginase and its application, which relates to the field of enzyme engineering. This invention successfully constructed a mutant with enhanced secretion of L-asparaginase through N-terminal deletion on amino acid sequence of L-asparaginase, and then expressed the mutant via a recombinant strain. Compared with the wild L-asparaginase, the secretion ability of L-asparaginase mutant in present invention significantly improves by 3.14 times compared to that of wild type. The recombinant strain that constructed in this prevention has an L-asparaginase yield of 407.6 U/mL and a production efficiency of 9.26 U/(mL/h), which reaches to the highest yield been reported.

Abstract: Disclosed herein are gear shifters to reverse an output shaft rotation and a method for using the same. A gear shifter in accordance with the present invention may include a housing, an input shaft, an output shaft and an idler shaft. The input shaft may have input gears, the output shaft may have output gears and the idler shaft may have idler gears. The output shaft may be slidably coupled with the input shaft and the idler shaft to rotate in a first direction in a first position and in a second opposite direction in a second position. A method of reversing an output shaft direction using a gear shifter may include the steps of pushing the gear shifter in a first direction to rotate the output shaft in a first direction and pushing the gear shifter in a second direction to rotate the output shaft in a second direction.

Abstract: A staple cartridge assembly comprises a connector, a cutter push rod and an elastic sheet, the elastic sheet having a first through groove and the cutter push rod being formed by laminating multiple sheets, wherein when the staple cartridge assembly is in an original status or a closed status, part of the cutter push rod is located in the first through groove, and the first through groove restricts detaching of the multiple sheets in a laminating direction of the multiple sheets; in a firing process of the staple cartridge assembly, the cutter push rod moves towards a distal end of the staple cartridge assembly to press the elastic sheet, such that the elastic sheet deforms and the cutter push rod is gradually detached from the first through groove; after the firing of the staple cartridge assembly is finished, the cutter push rod is detached from the first through groove.

Abstract: The present invention provides a mutant with enhanced secretion of L-asparaginase and its application, which relates to the field of enzyme engineering. This invention successfully constructed a mutant with enhanced secretion of L-asparaginase through N-terminal deletion on amino acid sequence of L-asparaginase, and then expressed the mutant via a recombinant strain. Compared with the wild L-asparaginase, the secretion ability of L-asparaginase mutant in present invention significantly improves by 3.14 times compared to that of wild type. The recombinant strain that constructed in this prevention has an L-asparaginase yield of 407.6 U/mL and a production efficiency of 9.26 U/(mL/h), which reaches to the highest yield been reported.

Abstract: Embodiments of the present invention relate to a method for improving handover performance in a cellular wireless communication system, said cellular wireless communication system employing a handover procedure in which a handover preparation for a mobile station is initiated if a channel quality value between a source cell for said mobile station and said mobile station is less than a channel quality threshold value; said method comprising: tuning said channel quality threshold value based on one or more handover performance criteria used in said cellular wireless communication system. Furthermore, the invention also relates to a device for improving handover performance, a computer program, and a computer program product thereof.

Abstract: The present disclosure relates to a radio resource scheduling method and apparatus. When a sending end receives a NACK message fed back by a receiving end, the method includes acquiring, by the sending end, data whose response message is the NACK message as data to be retransmitted, where the data to be retransmitted includes at least one transport block; and determining, by the sending end according to a RLC status report sent by the receiving end, whether the receiving end successfully receives each transport block of the data to be retransmitted. If all the transport blocks of the data to be retransmitted are successfully received, canceling retransmission of the data to be retransmitted; or if not all the transport blocks of the data to be retransmitted are successfully received, retransmitting a transport block that is in the data to be retransmitted and is not successfully received.

Abstract: An indexed file layout, comprising index information, is defined for segmented streaming of multimedia content. The index information can comprise program description information and streaming segment index information. In addition, the layout can comprise files containing streaming segments of the program, where the streaming segments are each encoded at one or more bitrates independently of other streaming segments of the program. The layout supports client switching between different bitrates at segment boundaries. Optimized client-side rate control of streaming content can be provided by defining a plurality of states, selecting available paths based on constraint conditions, and selecting a best path through the states (e.g., based on a distortion measure). In one client-side rate control solution states correspond to a specific bitrate of a specific streaming segment, and in another client-side rate control solution states correspond to a measure of client buffer fullness.

Abstract: A method for conversion treating a surface of a magnesium alloy workpiece includes the following steps: providing a magnesium alloy workpiece, degreasing the magnesium alloy workpiece, acid pickling the magnesium alloy workpiece in a first acid pickling treatment step, surface conditioning the magnesium alloy workpiece in a first surface conditioning treatment step, acid pickling the magnesium alloy workpiece in a second acid pickling treatment step, surface conditioning the magnesium alloy workpiece in a second surface conditioning treatment step, pre-phosphating the magnesium alloy workpiece in a pre-phosphating treatment step, and phosphating the magnesium alloy workpiece in a phosphating treatment step to form a phosphating film on the surface of the magnesium alloy workpiece.