Abstract: A display medium including a plurality of electrically photosensitive particles positioned within at least one ambipolar shell to form at least one first composite particle, and a plurality of white particles encapsulated in a plurality of insulating shells to form a plurality of second composite particles. A photoelectrophoretic display and method of photoelectrophoretic imaging are also disclosed.

Abstract: An apparatus and method of printing microarrays by ejecting droplets of electrically conducting liquids from wells (12) onto a substrate (21) on top of a charged plate (20) using electrodes (18) inserted into the wells (12).

Abstract: The present invention comprises an electromagnetophoretic ink material for use as electronic and magnetic display elements. In particular, the present invention relates to the preparation and use of microencapsulated aspect elements having both an electrostatic layer and a magnetic layer, and that can be addressed to produce a display aspect by the application of external electric fields and external magnetic fields.

Abstract: Provided is a priming mechanism for priming a biofluid drop ejection device having a drop ejection opening leading to an ejection reservoir. The priming mechanism includes a vacuum unit which generates a vacuum force, connected to a vacuum nozzle. The vacuum nozzle is located over the drop ejection opening. A disposable sleeve or tubing is attached to the vacuum nozzle and is placed in operational contact with the drop ejection opening. A fluid height detection sensor is positioned to sense a fluid height within at least one of the disposable tubing and the vacuum nozzle. Upon sensing a predetermined fluid height, by the fluid height detection sensor, the priming operation is completed, and the primer mechanism is removed from the operational contact with the drop ejection opening.

Abstract: The present invention comprises an electromagnetophoretic ink material for use as electronic and magnetic display elements. In particular, the present invention relates to the preparation and use of microencapsulated aspect elements having both an electrostatic layer and a magnetic layer, and that can be addressed to produce a display aspect by the application of external electric fields and external magnetic fields.

Abstract: Devices and methods are provided for administering a fluid to a neuronal site. The device comprises a reservoir, an aperture in fluid connection to the reservoir, and electrical means for moving to the fluid to or through the aperture. The electrical means may take the form of electroosmotic force, piezoelectric movement of a diaphragm or electrolysis of a solution. The electrical means may be external to the host, implanted in the host or may be photodiodes activated by light, particularly where the neuronal site is associated with the retina.

Abstract: A method of making a multichromal sphere includes the steps of preparing a composition of at least (1) a matrix material and (2) at least two sets of particles, each of the sets of particles having a color different from at least one of another of the sets of particles and a segregation (e.g., an electrical or magnetic) property different from at least one of another of the sets of particles, encapsulating the composition within a shell to form an encapsulated sphere, immobilizing the encapsulated sphere in a manner to restrict at least rotation of the encapsulated sphere, subjecting the immobilized encapsulated sphere to an external field associated with the segregation property different among the sets of particles, under conditions in which the sets of particles are able to migrate within the matrix material, thereby producing color segregation in the immobilized encapsulated sphere, and solidifying the matrix material while substantially maintaining the color segregation.

Abstract: An improved method for the sequencing of DNA fragments is provided. The method includes using a known process for DNA fragment separation, such as capillary electrophoresis, and imaging the resultant gel plate with a full-width array scanner or a two-dimensional amorphous silicon image sensor array. The DNA sample is placed within a well of the separation apparatus, such as a capillary tube or plurality thereof. The separation apparatus is then placed in a buffer. An electric field is then applied, forming a bias between the ends along which the sample is separated. Once separated, the large area detector scans the entire gel plate and resultant image data is provided. By way of the improved method, the entire gel plate can be scanned at the same time and repeatedly, resulting in greater accuracy and a shorter time to sequence.

Abstract: The present invention comprises an electromagnetophoretic ink material for use as electronic and magnetic display elements. In particular, the present invention relates to the preparation and use of microencapsulated aspect elements having both an electrostatic layer and a magnetic layer, and that can be addressed to produce a display aspect by the application of external electric fields and external magnetic fields.

Abstract: A particulate dispensing device includes a housing having a wall at least partially forming a housing cavity. A dispersive element and a particulate filter are each supported in the housing cavity in spaced relation to one another forming a fluidizing chamber. A dispensing tube extends from the fluidizing chamber for dispensing fluidized particulates or aerosol from the device. The particulate dispensing device generates the fluidized particulates or aerosol from a particulate bed within the fluidizing chamber, and dispense the particulates through the dispensing tube to a downstream delivery site. One or more dispensing devices can be used in a system to deliver the fluidized particulate matter to the delivery site. In one system a delivery line from an associated dispensing device directly delivers particulate matter to the delivery site.

Abstract: A display medium including a plurality of electrically photosensitive particles positioned within at least one ambipolar shell to form at least one first composite particle, and a plurality of white particles encapsulated in a plurality of insulating shells to form a plurality of second composite particles. A photoelectrophoretic display and method of photoelectrophoretic imaging are also disclosed.

Abstract: A reflective display device includes a flexible pouch of ordered copolymer layers with a lamellar structure and a solvent, the flexible pouch having at least a first and second surface. A substrate is placed in operative contact with a first surface of the flexible pouch. Thereafter, one of a pressure or heat application mechanism is placed in operative connection with at least one of the first and second surfaces of the flexible pouch. A controller operatively associated with one of the pressure or heat application mechanisms, is used to selectively apply pressure and/or heat to the flexible pouch. The application of the heat or pressure at a specific location on the flexible pouch results in a change of reflectivity in the ordered copolymer layers, thereby altering the color at that location.

Abstract: A particulate dispensing device includes a housing having a wall at least partially forming a housing cavity. A dispersive element and a particulate filter are each supported in the housing cavity in spaced relation to one another forming a fluidizing chamber. A dispensing tube extends from the fluidizing chamber for dispensing fluidized particulates or aerosol from the device. The particulate dispensing device generates the fluidized particulates or aerosol from a particulate bed within the fluidizing chamber, and dispense the particulates through the dispensing tube to a downstream delivery site. One or more dispensing devices can be used in a system to deliver the fluidized particulate matter to the delivery site. In one system a delivery line from an associated dispensing device directly delivers particulate matter to the delivery site.

Abstract: A method of making a print head is disclosed for use in a marking apparatus in which a propellant stream is passed through a channel and directed toward a substrate. Marking material, such as ink, toner, etc., is controllably introduced into the propellant stream and imparted with sufficient kinetic energy thereby to be made incident upon a substrate. A multiplicity of channels for directing the propellant and marking material allow for high throughput, high resolution marking. Multiple marking materials may be introduced into the channel and mixed therein prior to being made incident on the substrate, or mixed or superimposed on the substrate without re-registration.

Abstract: Methods for testing proper operation of drop ejection units in a multi-ejector system are provided to determine whether the drop ejectors have been properly filled and/or the ejectors are emitting fully formed droplets. The methods include testing the ejectors prior to drop ejection. In this method, a priming system is used wherein fluid received by the priming system is ejected onto a test substrate to allow a scanner to determine the existence of the fluids at selected locations. The selected locations are correlated to the drop ejection units to determine which ejection units do not have biofluid or sufficient biofluid. A further method allows for ejection prior to printing, on a test substrate wherein testing for both the fullness of the ejector units as well as proper emission of the ejectors of droplets may be tested. The ejectors after being primed, eject the biofluids which are then scanned and correlated to each individual ejector.

Abstract: A method for providing three dimensional optical memory storage for computers. The method comprises subjecting a nanocomposite to irradiation. The nanocomposite comprises a matrix of particles of a liquid core resin within an inner shell resin and an outer shell resin. The inner shell resin retains the liquid core resin while the outer shell resin forms a continuous phase of the matrix. The particles of core resin contain at least one photosensitive compound and are in an array in the matrix. The continuous phase is substantially free of photosensitive compound. The irradiation may be a single beam of irradiation selectively focused on individual particles in the array to effect photobleaching of individual particles or a two-photon irradiation of a wavelength to effect photobleaching.

Abstract: Disclosed is a process for depositing marking material onto a substrate which comprises (a) providing a propellant to a printhead, said printhead having defined therein at least one channel, each channel having an inner surface and an exit orifice with a width no larger than about 250 microns through which the propellant can flow, said propellant flowing through each channel, thereby forming a propellant stream having kinetic energy, each channel directing the propellant stream toward the substrate, the inner surface of each channel having thereon a conductive polymer coating; and (b) controllably introducing a particulate marking material into the propellant stream in each channel, wherein the kinetic energy of the propellant stream causes the particulate marking material to impact the substrate.

Abstract: A biofluid drop ejection unit for ejecting biofluid drops. A biofluid drop ejection mechanism of such a unit includes a transducer, which generates energy used to emit the biofluid drop. Further provided is a reagent cartridge or biofluid containment area which holds the biofluid. The reagent cartridge or biofluid containment area is configured to hold low volumes of biofluid and to avoid contamination of the biofluid. The reagent cartridge or biofluid containment area is in operational connection with the drop ejection mechanism such that upon operation of the drop ejection mechanism, biofluid drops are emitted. The biofluid drop ejection mechanism is a high efficiency device, and may be configured as two separate pieces or as a single disposable unit.

Abstract: The invention provides implants suitable for use as an artificial cornea, and methods for making and using such implants. Artificial corneas having features of the invention may be two-phase artificial corneas, or may be three phase artificial corneas. These artificial corneas have a flexible, optically clear central core and a hydrophilic, porous skirt, both of which are biocompatible and allow for tissue integration. A three-phase artificial cornea will further have an interface region between the core and skirt. The artificial corneas have a high degree of ocular tolerance, and allow for tissue integration into the skirt and for epithelial cell growth over the surface of the prosthesis. The use of biocompatible material avoids the risk of disease transmission inherent with corneal transplants, and acts to minimize post-operative inflammation and so to reduce the chance or severity of tissue necrosis following implantation of the synthetic cornea onto a host eye.

Abstract: Disclosed is a process for depositing marking material onto a substrate which comprises (a) providing a propellant to a printhead, said printhead having defined therein at least one channel, each channel having an inner surface and an exit orifice with a width no larger than about 250 microns through which the propellant can flow, said propellant flowing through each channel, thereby forming a propellant stream having kinetic energy, each channel directing the propellant stream toward the substrate, the inner surface of each channel having thereon a conductive polymer coating; and (b) controllably introducing a particulate marking material into the propellant stream in each channel, wherein the kinetic energy of the propellant stream causes the particulate marking material to impact the substrate.