Patents by Inventor Jack Newman
Jack Newman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230367602Abstract: A computer-implemented method is presented. The method comprises sequentially receiving a plurality of utterance prefixes, each sequentially received utterance prefix derived from a progressively longer incomplete portion of a full user utterance. For each sequentially received utterance prefix, a complete dataflow program is predicted based on the utterance prefix. The complete dataflow program includes a plurality of program nodes to be executed to satisfy the full user utterance. One or more program nodes are selected from the predicted complete dataflow program to speculatively execute based on at least the utterance prefix.Type: ApplicationFiled: July 28, 2022Publication date: November 16, 2023Applicant: Microsoft Technology Licensing, LLCInventors: Jason Michael EISNER, Samuel McIntire THOMSON, Michael Jack NEWMAN, Emmanouil Antonios PLATANIOS, Jiawei ZHOU
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Patent number: 11289085Abstract: A method of automatically delineating turns in a multi-turn dialogue between a user and a conversational computing interface. Audio data encoding speech of the user in the multi-turn dialogue is received. The audio data is analyzed to recognize, in the speech of the user, an utterance followed by a silence. The utterance is recognized as a last utterance in a turn of the multi-turn dialogue responsive to the silence exceeding a context-dependent duration dynamically updated based on a conversation history of the multi-turn dialogue and features of the received audio, wherein the conversation history includes one or more previous turns of the multi-turn dialogue taken by the user and one or more previous turns of the multi-turn dialogue taken by the conversational computing interface.Type: GrantFiled: November 26, 2019Date of Patent: March 29, 2022Assignee: Microsoft Technology Licensing, LLCInventors: Charles Clayton Wooters, Steven Andrew Wegmann, Michael Jack Newman, David Leo Wright Hall, Jean Crawford, Laurence Steven Gillick
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Publication number: 20210158812Abstract: A method of automatically delineating turns in a multi-turn dialogue between a user and a conversational computing interface. Audio data encoding speech of the user in the multi-turn dialogue is received. The audio data is analyzed to recognize, in the speech of the user, an utterance followed by a silence. The utterance is recognized as a last utterance in a turn of the multi-turn dialogue responsive to the silence exceeding a context-dependent duration dynamically updated based on a conversation history of the multi-turn dialogue and features of the received audio, wherein the conversation history includes one or more previous turns of the multi-turn dialogue taken by the user and one or more previous turns of the multi-turn dialogue taken by the conversational computing interface.Type: ApplicationFiled: November 26, 2019Publication date: May 27, 2021Applicant: Microsoft Technology Licensing, LLCInventors: Charles Clayton WOOTERS, Steven Andrew WEGMANN, Michael Jack NEWMAN, David Leo Wright HALL, Jean CRAWFORD, Laurence Steven GILLICK
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Patent number: 10106822Abstract: Methods for producing an isoprenoid are provided. A plurality of bacterial or fungal host cells is obtained. These cells comprise a heterologous nucleic acid encoding one or more enzymes of a mevalonate pathway for making isopentenyl pyrophosphate. Expression of the one or more enzymes is under control one or more heterologous transcriptional regulator. The mevalonate pathway comprises (i) an enzyme that condenses acetoacetyl-CoA with acetyl-CoA to form HMG-CoA, (ii) an enzyme that converts HMG-CoA to mevalonate, (iii) an enzyme that phosphorylates mevalonate to mevalonate 5-phosphate, (iv) an enzyme that converts mevalonate 5-phosphate to mevalonate 5-pyrophosphate, and (v) an enzyme that converts mevalonate 5-pyrophosphate to isopentenyl pyrophosphate. The host cells are cultured in a medium under conditions that are suboptimal as compared to conditions for the maximum growth rate. Temperature is maintained at a level below that which would provide for a maximum specific growth rate for the host cells.Type: GrantFiled: October 23, 2015Date of Patent: October 23, 2018Assignee: Amyris, Inc.Inventors: Neil Stephen Renninger, Jack Newman, Keith Kinkead Reiling, Rika Regentin, Christopher John Paddon
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Publication number: 20160040190Abstract: Methods for producing an isoprenoid are provided. A plurality of bacterial or fungal host cells is obtained. These cells comprise a heterologous nucleic acid encoding one or more enzymes of a mevalonate pathway for making isopentenyl pyrophosphate. Expression of the one or more enzymes is under control one or more heterologous transcriptional regulator. The mevalonate pathway comprises (i) an enzyme that condenses acetoacetyl-CoA with acetyl-CoA to form HMG-CoA, (ii) an enzyme that converts HMG-CoA to mevalonate, (iii) an enzyme that phosphorylates mevalonate to mevalonate 5-phosphate, (iv) an enzyme that converts mevalonate 5-phosphate to mevalonate 5-pyrophosphate, and (v) an enzyme that converts mevalonate 5-pyrophosphate to isopentenyl pyrophosphate. The host cells are cultured in a medium under conditions that are suboptimal as compared to conditions for the maximum growth rate. Temperature is maintained at a level below that which would provide for a maximum specific growth rate for the host cells.Type: ApplicationFiled: October 23, 2015Publication date: February 11, 2016Inventors: Neil Stephen RENNINGER, Jack Newman, Keith Kinkead Reiling, Rika Regentin, Christopher John Paddon
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Patent number: 9200296Abstract: Methods for producing an isoprenoid are provided. A plurality of bacterial or fungal host cells is obtained. These cells comprise a heterologous nucleic acid encoding one or more enzymes of a mevalonate pathway for making isopentenyl pyrophosphate. Expression of the one or more enzymes is under control of at least one heterologous transcriptional regulator. The mevalonate pathway comprises (i) an enzyme that condenses acetoacetyl-CoA with acetyl-CoA to form HMG-CoA, (ii) an enzyme that converts HMG-CoA to mevalonate, (iii) an enzyme that phosphorylates mevalonate to mevalonate 5-phosphate, (iv) an enzyme that converts mevalonate 5-phosphate to mevalonate 5-pyrophosphate, and (v) an enzyme that converts mevalonate 5-pyrophosphate to isopentenyl pyrophosphate. The host cells are cultured in a medium under conditions that are suboptimal as compared to conditions for the maximum growth rate. Temperature is maintained at a level below that which would provide for a maximum specific growth rate for the host cells.Type: GrantFiled: March 20, 2013Date of Patent: December 1, 2015Assignee: Amyris Inc.Inventors: Neil Stephen Renninger, Jack Newman, Keith Kinkead Reiling, Rika Regentin, Christopher John Paddon
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Patent number: 9117449Abstract: Techniques disclosed herein include systems and methods that enable a voice trigger that wakes-up an electronic device or causes the device to make additional voice commands active, without manual initiation of voice command functionality. In addition, such a voice trigger is dynamically programmable or customizable. A speaker can program or designate a particular phrase as the voice trigger. In general, techniques herein execute a voice-activated wake-up system that operates on a digital signal processor (DSP) or other low-power, secondary processing unit of an electronic device instead of running on a central processing unit (CPU). A speech recognition manager runs two speech recognition systems on an electronic device. The CPU dynamically creates a compact speech system for the DSP. Such a compact system can be continuously run during a standby mode, without quickly exhausting a battery supply.Type: GrantFiled: April 26, 2012Date of Patent: August 25, 2015Assignee: Nuance Communications, Inc.Inventors: Michael Jack Newman, Robert Roth, William D. Alexander, Paul van Mulbregt
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Publication number: 20130289994Abstract: Techniques disclosed herein include systems and methods that enable a voice trigger that wakes-up an electronic device or causes the device to make additional voice commands active, without manual initiation of voice command functionality. In addition, such a voice trigger is dynamically programmable or customizable. A speaker can program or designate a particular phrase as the voice trigger. In general, techniques herein execute a voice-activated wake-up system that operates on a digital signal processor (DSP) or other low-power, secondary processing unit of an electronic device instead of running on a central processing unit (CPU). A speech recognition manager runs two speech recognition systems on an electronic device. The CPU dynamically creates a compact speech system for the DSP. Such a compact system can be continuously run during a standby mode, without quickly exhausting a battery supply.Type: ApplicationFiled: April 26, 2012Publication date: October 31, 2013Inventors: Michael Jack Newman, Robert Roth, William D. Alexander, Paul van Mulbregt
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Publication number: 20130252295Abstract: Methods for producing an isoprenoid are provided. A plurality of bacterial or fungal host cells is obtained. These cells comprise a heterologous nucleic acid encoding one or more enzymes of a mevalonate pathway for making isopentenyl pyrophosphate. Expression of the one or more enzymes is under control of at least one heterologous transcriptional regulator. The mevalonate pathway comprises (i) an enzyme that condenses acetoacetyl-CoA with acetyl-CoA to form HMG-CoA, (ii) an enzyme that converts HMG-CoA to mevalonate, (iii) an enzyme that phosphorylates mevalonate to mevalonate 5-phosphate, (iv) an enzyme that converts mevalonate 5-phosphate to mevalonate 5-pyrophosphate, and (v) an enzyme that converts mevalonate 5-pyrophosphate to isopentenyl pyrophosphate. The host cells are cultured in a medium under conditions that are suboptimal as compared to conditions. Temperature is maintained at a level below that which would provide for a maximum specific growth rate for the host cells.Type: ApplicationFiled: March 20, 2013Publication date: September 26, 2013Inventors: Neil Stephen Renninger, Jack Newman, Keith Kinkead Reiling, Rika Regentin, Christopher John Paddon
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Patent number: 8288147Abstract: Methods for synthesizing isopentenyl pyrophosphate are provided. A first method comprises introducing into a host microorganism a plurality of heterologous nucleic acid sequences, each coding for a different enzyme in the mevalonate pathway for producing isopentenyl pyrophosphate. A related method comprises introducing into a host microorganism an intermediate in the mevalonate pathway and at least one heterologous nucleic acid sequence, each sequence coding for an enzyme in the mevalonate pathway necessary for converting the intermediate into isopentenyl pyrophosphate. The invention also provides nucleic acid sequences, enzymes, expression vectors, and transformed host cells for carrying out the methods.Type: GrantFiled: February 15, 2011Date of Patent: October 16, 2012Assignee: The Regents of the University of CaliforniaInventors: Jay D. Keasling, Vincent J.J. Martin, Douglas J. Pitera, Seon-Won Kim, Sydnor T. Withers, III, Yasuo Yoshikuni, Jack Newman, Artem Valentinovich Khlebnikov
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Publication number: 20110287476Abstract: The present invention provides methods for a robust production of isoprenoids via one or more biosynthetic pathways. The invention also provides nucleic acids, enzymes, expression vectors, and genetically modified host cells for carrying out the subject methods. The invention also provides fermentation methods for high productivity of isoprenoids from genetically modified host cells.Type: ApplicationFiled: December 15, 2009Publication date: November 24, 2011Inventors: Neil Stephen Renninger, Jack Newman, Keith Kinkead Reiling, Rika Regentin, Christopher John Paddon
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Publication number: 20110229958Abstract: Methods for synthesizing isopentenyl pyrophosphate are provided. A first method comprises introducing into a host microorganism a plurality of heterologous nucleic acid sequences, each coding for a different enzyme in the mevalonate pathway for producing isopentenyl pyrophosphate. A related method comprises introducing into a host microorganism an intermediate in the mevalonate pathway and at least one heterologous nucleic acid sequence, each sequence coding for an enzyme in the mevalonate pathway necessary for converting the intermediate into isopentenyl pyrophosphate. The invention also provides nucleic acid sequences, enzymes, expression vectors, and transformed host cells for carrying out the methods.Type: ApplicationFiled: February 15, 2011Publication date: September 22, 2011Inventors: JAY KEASLING, Vincent Martin, Douglas Pitera, Seon-Won Kim, Sydnor T. Withers, III, Yasuo Yoshikuni, Jack Newman, Artem Valentinovich Khlebnikov
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Patent number: 7915026Abstract: Methods for synthesizing isopentenyl pyrophosphate are provided. A first method comprises introducing into a host microorganism a plurality of heterologous nucleic acid sequences, each coding for a different enzyme in the mevalonate pathway for producing isopentenyl pyrophosphate. A related method comprises introducing into a host microorganism an intermediate in the mevalonate pathway and at least one heterologous nucleic acid sequence, each sequence coding for an enzyme in the mevalonate pathway necessary for converting the intermediate into isopentenyl pyrophosphate. The invention also provides nucleic acid sequences, enzymes, expression vectors, and transformed host cells for carrying out the methods.Type: GrantFiled: October 8, 2009Date of Patent: March 29, 2011Assignee: The Regents of the University of CaliforniaInventors: Jay D. Keasling, Vincent J. J. Martin, Douglas J. Pitera, Seon-Won Kim, Sydnor T. Withers, III, Yasuo Yoshikuni, Jack Newman, Artem Valentinovich Khlebnikov
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Publication number: 20100178679Abstract: The present invention provides methods for a robust production of isoprenoids utilizing the DXP biosynthetic path-way. The invention also provides nucleic acids, enzymes, expression vectors, and genetically modified host cells for carrying out the subject methods.Type: ApplicationFiled: April 14, 2008Publication date: July 15, 2010Inventors: Larry Anthony, Jack Newman
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Patent number: 7736882Abstract: Methods for synthesizing isopentenyl pyrophosphate are provided. A first method comprises introducing into a host microorganism a plurality of heterologous nucleic acid sequences, each coding for a different enzyme in the mevalonate pathway for producing isopentenyl pyrophosphate. A related method comprises introducing into a host microorganism an intermediate in the mevalonate pathway and at least one heterologous nucleic acid sequence, each sequence coding for an enzyme in the mevalonate pathway necessary for converting the intermediate into isopentenyl pyrophosphate. The invention also provides nucleic acid sequences, enzymes, expression vectors, and transformed host cells for carrying out the methods.Type: GrantFiled: December 14, 2006Date of Patent: June 15, 2010Assignee: The Regents of the University of CaliforniaInventors: Jay D. Keasling, Vincent J. J. Martin, Douglas J. Pitera, Seon-Won Kim, Sydnor T. Withers, III, Yasuo Yoshikuni, Jack Newman, Artem Valentinovich Khlebnikov
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Publication number: 20100112671Abstract: Methods for synthesizing isopentenyl pyrophosphate are provided. A first method comprises introducing into a host microorganism a plurality of heterologous nucleic acid sequences, each coding for a different enzyme in the mevalonate pathway for producing isopentenyl pyrophosphate. A related method comprises introducing into a host microorganism an intermediate in the mevalonate pathway and at least one heterologous nucleic acid sequence, each sequence coding for an enzyme in the mevalonate pathway necessary for converting the intermediate into isopentenyl pyrophosphate. The invention also provides nucleic acid sequences, enzymes, expression vectors, and transformed host cells for carrying out the methods.Type: ApplicationFiled: October 8, 2009Publication date: May 6, 2010Inventors: JAY D. KEASLING, Vincent Martin, Douglas Pitera, Seon-Won Kim, Sydnor T. Withers, III, Yasuo Yoshikuni, Jack Newman, Artem Valentinovich Khlebnikov
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Patent number: 7659097Abstract: The present invention provides methods for a robust production of isoprenoids via one or more biosynthetic pathways. The invention also provides nucleic acids, enzymes, expression vectors, and genetically modified host cells for carrying out the subject methods. The invention also provides fermentation methods for high productivity of isoprenoids from genetically modified host cells.Type: GrantFiled: May 25, 2007Date of Patent: February 9, 2010Assignee: Amyris Biotechnologies, Inc.Inventors: Neil Stephen Renninger, Jack Newman, Keith Kinkead Reiling, Rika Regentin, Christopher John Paddon
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Patent number: 7622283Abstract: Methods for synthesizing isopentenyl pyrophosphate are provided. A first method comprises introducing into a host microorganism a plurality of heterologous nucleic acid sequences, each coding for a different enzyme in the mevalonate pathway for producing isopentenyl pyrophosphate. A related method comprises introducing into a host microorganism an intermediate in the mevalonate pathway and at least one heterologous nucleic acid sequence, each sequence coding for an enzyme in the mevalonate pathway necessary for converting the intermediate into isopentenyl pyrophosphate. The invention also provides nucleic acid sequences, enzymes, expression vectors, and transformed host cells for carrying out the methods.Type: GrantFiled: December 14, 2006Date of Patent: November 24, 2009Assignee: The Regents of the University of CaliforniaInventors: Jay D. Keasling, Vinent J. J. Martin, Douglas J. Pitera, Seon-Won Kim, Sydnor T. Withers, III, Yasuo Yoshikuni, Jack Newman, Artem Valentinovich Khlebnikov
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Patent number: 7622282Abstract: Methods for synthesizing isopentenyl pyrophosphate are provided. A first method comprises introducing into a host microorganism a plurality of heterologous nucleic acid sequences, each coding for a different enzyme in the mevalonate pathway for producing isopentenyl pyrophosphate. A related method comprises introducing into a host microorganism an intermediate in the mevalonate pathway and at least one heterologous nucleic acid sequence, each sequence coding for an enzyme in the mevalonate pathway necessary for converting the intermediate into isopentenyl pyrophosphate. The invention also provides nucleic acid sequences, enzymes, expression vectors, and transformed host cells for carrying out the methods.Type: GrantFiled: December 13, 2006Date of Patent: November 24, 2009Assignee: The Regents of the University of CaliforniaInventors: Jay D. Keasling, Vincent J. J. Martin, Douglas J. Pitera, Seon-Won Kim, Sydnor T. Withers, III, Yasuo Yoshikuni, Jack Newman, Artem Valentinovich Khlebnikov
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Publication number: 20080274523Abstract: The present invention provides methods for a robust production of isoprenoids via one or more biosynthetic pathways. The invention also provides nucleic acids, enzymes, expression vectors, and genetically modified host cells for carrying out the subject methods. The invention also provides fermentation methods for high productivity of isoprenoids from genetically modified host cells.Type: ApplicationFiled: May 25, 2007Publication date: November 6, 2008Inventors: Neil Stephen Renninger, Jack Newman, Keith Kinkead Rolling, Rika Regentin, Christopher John Paddon