Patents by Inventor James F. White

James F. White has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110251175
    Abstract: The invention relates to methods for the treatment or prevention of substance use disorders.
    Type: Application
    Filed: July 16, 2009
    Publication date: October 13, 2011
    Inventors: Nadia Rupniak, James F. White
  • Patent number: 7994347
    Abstract: A method of reducing hydroxymethylfurfural (HMF) where a starting material containing HMF in a solvent comprising water is provided. H2 is provided into the reactor and the starting material is contacted with a catalyst containing at least one metal selected from Ni, Co, Cu, Pd, Pt, Ru, Ir, Re and Rh, at a temperature of less than or equal to 250° C. A method of hydrogenating HMF includes providing an aqueous solution containing HMF and fructose. H2 and a hydrogenation catalyst are provided. The HMF is selectively hydrogenated relative to the fructose at a temperature at or above 30° C. A method of producing tetrahydrofuran dimethanol (THFDM) includes providing a continuous flow reactor having first and second catalysts and providing a feed comprising HMF into the reactor. The feed is contacted with the first catalyst to produce furan dimethanol (FDM) which is contacted with the second catalyst to produce THFDM.
    Type: Grant
    Filed: June 8, 2007
    Date of Patent: August 9, 2011
    Assignee: Battelle Memorial Institute
    Inventors: Michael A. Lilga, Richard T. Hallen, Todd A. Werpy, James F. White, Johnathan E. Holladay, John G. Frye, Jr., Alan H. Zacher
  • Patent number: 7973177
    Abstract: The invention includes methods of processing an initial di-carbonyl compound by conversion to a cyclic compound. The cyclic compound is reacted with an alkylating agent to form a derivative having an alkylated ring nitrogen. The invention encompasses a method of producing an N-alkyl product. Ammonia content of a solution is adjusted to produce a ratio of ammonia to di-carboxylate compound of from about 1:1 to about 1.5:1. An alkylating agent is added and the initial compound is alkylated and cyclized. The invention includes methods of making N-methylpyrrolidinone (NMP). Aqueous ammonia and succinate is introduced into a vessel and ammonia is adjusted to provide a ratio of ammonia to succinate of less than 2:1. A methylating agent is reacted with succinate at a temperature of from greater than 100° C. to about 400° C. to produce N-methyl succinimide which is purified and hydrogenated to form NMP.
    Type: Grant
    Filed: February 9, 2010
    Date of Patent: July 5, 2011
    Assignee: Battelle Memorial Institute
    Inventors: Todd A. Werpy, John G. Frye, Jr., James F. White, Johnathan E. Holladay, Alan H. Zacher
  • Publication number: 20110152582
    Abstract: The present disclosure relates to facilities, systems, methods and/or catalysts for use in chemical production. In particular, the disclosure provides innovations relating to dehydration of multihydric compounds such as glycerol to form acrolein. Some of these innovations include continuous reaction systems as well as system parameters that allow for long term production.
    Type: Application
    Filed: December 20, 2010
    Publication date: June 23, 2011
    Inventors: James J. Strohm, Alan H. Zacher, James F. White, Michel J. Gray, Vanessa Lebarbier
  • Patent number: 7872158
    Abstract: Chemical production processes are provided that can include exposing a reactant composition to a catalyst composition to form a product composition. The reactant composition can include a multihydric alcohol compound and the product composition can include a carbonyl compound. The catalyst composition can include a metal effective to facilitate catalyst activation. Processes disclosed also include supplementing a dehydration catalyst with a promoter, and activating the supplemented catalyst in the presence of oxygen. Processes also include providing a supplemented dehydration catalyst to within a reactor, and exposing a multihydric alcohol compound to the dehydration catalyst, with the exposing forming coke within the reactor. Oxygen can be provided to the reactor to remove at least a portion of the coke.
    Type: Grant
    Filed: August 24, 2007
    Date of Patent: January 18, 2011
    Assignee: Battelle Memorial Institute
    Inventors: Thomas H. Peterson, Alan H. Zacher, Michel J. Gray, James F. White, Todd A. Werpy
  • Patent number: 7872159
    Abstract: Chemical production processes are provided that can include exposing a reactant composition to a catalyst composition to form a product composition. Catalyst compositions are also provided that can include metal phosphate compositions, metal phosphorous compositions, and/or solid support compositions with the solid support compositions including one or more of F—Al2O3, ZrO2—CO2, SiO2—Al2O3—CO2, SiO2 Al2O3, Alundum, and Silica such as Ludox AS-30.
    Type: Grant
    Filed: August 24, 2007
    Date of Patent: January 18, 2011
    Assignee: Battelle Memorial Institute
    Inventors: Thomas H. Peterson, Alan H. Zacher, Michel J. Gray, James F. White, Todd A. Werpy
  • Patent number: 7858667
    Abstract: Methods for producing alcohols from CO or CO2 and H2 utilizing a palladium-zinc on alumina catalyst are described. Methods of synthesizing alcohols over various catalysts in microchannels are also described. Ethanol, higher alcohols, and other C2+ oxygenates can produced utilizing Rh—Mn or a Fisher-Tropsch catalyst.
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: December 28, 2010
    Assignee: Battelle Memorial Institute
    Inventors: Jianli Hu, Robert A. Dagle, Jamelyn D. Holladay, Chunshe Cao, Yong Wang, James F. White, Douglas C. Elliott, Don J. Stevens
  • Publication number: 20100256187
    Abstract: The present invention relates to discloses a pharmaceutical composition of 2,4,6-trifluoro-N-[6-(1-methyl-piperidin-4-ylcarbonyl)-pyridin-2-yl]-benzamide and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: April 2, 2010
    Publication date: October 7, 2010
    Applicant: CoLucid Pharmaceuticals, Inc.
    Inventors: Alison Pilgrim, James F. White, Nadia M.J. Rupniak
  • Publication number: 20100152470
    Abstract: A method of oxidizing hydroxymethylfurfural (HMF) includes providing a starting material which includes HMF in a solvent comprising water into a reactor. At least one of air and O2 is provided into the reactor. The starting material is contacted with the catalyst comprising Pt on a support material where the contacting is conducted at a reactor temperature of from about 50° C. to about 200° C. A method of producing an oxidation catalyst where ZrO2 is provided and is calcined. The ZrO2 is mixed with platinum (II) acetylacetonate to form a mixture. The mixture is subjected to rotary evaporation to form a product. The product is calcined and reduced under hydrogen to form an activated product. The activated product is passivated under a flow of 2% O2.
    Type: Application
    Filed: February 24, 2010
    Publication date: June 17, 2010
    Applicant: BATTELLE MEMORIAL INSTITUTE
    Inventors: Michael A. Lilga, Richard T. Hallen, Jianli Hu, James F. White, Michel J. Gray
  • Publication number: 20100152469
    Abstract: A method of oxidizing hydroxymethylfurfural (HMF) includes providing a starting material which includes HMF in a solvent comprising water into a reactor. At least one of air and O2 is provided into the reactor. The starting material is contacted with the catalyst comprising Pt on a support material where the contacting is conducted at a reactor temperature of from about 50° C. to about 200° C. A method of producing an oxidation catalyst where ZrO2 is provided and is calcined. The ZrO2 is mixed with platinum (II) acetylacetonate to form a mixture. The mixture is subjected to rotary evaporation to form a product. The product is calcined and reduced under hydrogen to form an activated product. The activated product is passivated under a flow of 2% O2.
    Type: Application
    Filed: February 24, 2010
    Publication date: June 17, 2010
    Applicant: BATTELLE MEMORIAL INSTITUTE
    Inventors: Michael A. Lilga, Richard T. Hallen, Jianli Hu, James F. White, Michel J. Gray
  • Publication number: 20100145072
    Abstract: The invention includes methods of processing an initial di-carbonyl compound by conversion to a cyclic compound. The cyclic compound is reacted with an alkylating agent to form a derivative having an alkylated ring nitrogen. The invention encompasses a method of producing an N-alkyl product. Ammonia content of a solution is adjusted to produce a ratio of ammonia to di-carboxylate compound of from about 1:1 to about 1.5:1. An alkylating agent is added and the initial compound is alkylated and cyclized. The invention includes methods of making N-methylpyrrolidinone (NMP). Aqueous ammonia and succinate is introduced into a vessel and ammonia is adjusted to provide a ratio of ammonia to succinate of less than 2:1. A methylating agent is reacted with succinate at a temperature of from greater than 100° C. to about 400° C. to produce N-methyl succinimide which is purified and hydrogenated to form NMP.
    Type: Application
    Filed: February 9, 2010
    Publication date: June 10, 2010
    Applicant: BATTELLE MEMORIAL INSTITUTE
    Inventors: Todd A. Werpy, John G. Frye, JR., James F. White, Johnathan E. Holladay, Alan H. Zacher
  • Patent number: 7708955
    Abstract: The invention provides methods and systems for alkylating a paraffinic feed stream in a microchannel utilizing the staged addition of olefin.
    Type: Grant
    Filed: October 9, 2007
    Date of Patent: May 4, 2010
    Assignee: Battelle Memorial Institute
    Inventors: Yong Wang, James F. White
  • Patent number: 7700788
    Abstract: A method of oxidizing hydroxymethylfurfural (HMF) includes providing a starting material which includes HMF in a solvent comprising water into a reactor. At least one of air and O2 is provided into the reactor. The starting material is contacted with the catalyst comprising Pt on a support material where the contacting is conducted at a reactor temperature of from about 50° C. to about 200° C. A method of producing an oxidation catalyst where ZrO2 is provided and is calcined. The ZrO2 is mixed with platinum (II) acetylacetonate to form a mixture. The mixture is subjected to rotary evaporation to form a product. The product is calcined and reduced under hydrogen to form an activated product. The activated product is passivated under a flow of 2% O2.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: April 20, 2010
    Assignee: Battelle Memorial Institute
    Inventors: Michael A. Lilga, Richard T. Hallen, Jianli Hu, James F. White, Michel J. Gray
  • Patent number: 7687661
    Abstract: A process is disclosed for conversion of salts of ?-hydroxy carbonyl compounds forming useful conversion products including, e.g., ?,?-unsaturated carbonyl compounds and/or salts of ?,?-unsaturated carbonyl compounds. Conversion products find use, e.g., as feedstock and/or end-use chemicals.
    Type: Grant
    Filed: March 15, 2006
    Date of Patent: March 30, 2010
    Assignee: Battelle Memorial Institute
    Inventors: Michael A. Lilga, James F. White, Johnathan E. Holladay, Alan H. Zacher, Danielle S. Muzatko, Rick J. Orth
  • Patent number: 7674916
    Abstract: The invention includes methods of processing an initial di-carbonyl compound by conversion to a cyclic compound. The cyclic compound is reacted with an alkylating agent to form a derivative having an alkylated ring nitrogen. The invention encompasses a method of producing an N-alkyl product. Ammonia content of a solution is adjusted to produce a ratio of ammonia to di-carboxylate compound of from about 1:1 to about 1.5:1. An alkylating agent is added and the initial compound is alkylated and cyclized. The invention includes methods of making N-methyl pyrrolidinone (NMP). Aqueous ammonia and succinate is introduced into a vessel and ammonia is adjusted to provide a ratio of ammonia to succinate of less than 2:1. A methylating agent is reacted with succinate at a temperature of from greater than 100° C. to about 400° C. to produce N-methyl succinimide which is purified and hydrogenated to form NMP.
    Type: Grant
    Filed: March 19, 2007
    Date of Patent: March 9, 2010
    Assignee: Battelle Memorial Institute
    Inventors: Todd A. Werpy, John G. Frey, Jr., James F. White, Johnathan E. Holladay, Alan H. Zacher
  • Patent number: 7607275
    Abstract: An apparatus and method for bundling shingles includes a sorting mechanism for separating and stacking shingles into multiple bundles of sorted shingles such that each bundle has a different repeating sequence of shingles.
    Type: Grant
    Filed: July 7, 2005
    Date of Patent: October 27, 2009
    Assignee: Owens Corning Intellectual Capital, LLC
    Inventors: Bert W. Elliott, Meghan L. Howard, James F. White
  • Publication number: 20090264687
    Abstract: Hydrogenolysis systems are provided that can include a reactor housing an Ru-comprising hydrogenolysis catalyst and wherein the contents of the reactor is maintained at a neutral or acidic pH. Reactant reservoirs within the system can include a polyhydric alcohol compound and a base, wherein a weight ratio of the base to the compound is less than 0.05. Systems also include the product reservoir comprising a hydrogenolyzed polyhydric alcohol compound and salts of organic acids, and wherein the moles of base are substantially equivalent to the moles of salts or organic acids. Processes are provided that can include an Ru-comprising catalyst within a mixture having a neutral or acidic pH. A weight ratio of the base to the compound can be between 0.01 and 0.05 during exposing.
    Type: Application
    Filed: April 16, 2008
    Publication date: October 22, 2009
    Inventors: Johnathan E. Holladay, Danielle S. Muzatko, James F. White, Alan H. Zacher
  • Publication number: 20090264686
    Abstract: Hydrogenolysis processes are provided that can include providing a hydrogenolysis reactor having a catalyst therein. The catalyst can be exposed to a reducing agent in the absence of polyhydric alcohol compound while maintaining a temperature of the catalyst above 290° C. Hydrogenolysis processes can also include providing a passivated catalyst to within a reactor and exposing the catalyst to a reducing atmosphere while maintaining the catalyst at a temperature less than 210° C. Hydrogenolysis catalyst preparation methods are provided that can include exposing the catalyst to a first reducing atmosphere while maintaining the catalyst at a first temperature to reduce at least a portion of the catalyst. The method can also include passivating at least the portion of the catalyst and depassivating the portion of the catalyst in the presence of a second reducing atmosphere while maintaining the portion of the catalyst at a second temperature less than the first temperature.
    Type: Application
    Filed: April 16, 2008
    Publication date: October 22, 2009
    Inventors: Johnathan E. Holladay, James F. White, Thomas H. Peterson, John G. Frye, JR., Danielle S. Muzatko, Simon R. Bare, James G. Vassilakis, Richard R. Rosin
  • Patent number: 7592333
    Abstract: The invention relates to novel compounds and methods of using them for modulating sleep.
    Type: Grant
    Filed: September 21, 2005
    Date of Patent: September 22, 2009
    Assignee: Hypnion, Inc.
    Inventors: Dale M. Edgar, David G. Hangauer, Kazumi Shiosaki, Michael Solomon, James F. White
  • Publication number: 20090186872
    Abstract: The invention relates to novel compounds and methods of using them for modulating sleep.
    Type: Application
    Filed: March 25, 2009
    Publication date: July 23, 2009
    Inventors: Dale M. Edgar, David G. Hangauer, Kazumi Shiosaki, Michael Solomon, James F. White