Abstract: A methods of placing large bore aspiration catheters is disclosed. The method of removing a vascular obstruction includes the steps of transvascularly advancing a distal end of an aspiration catheter into proximity with an obstruction, activating a low flow, detection mode of aspiration through the catheter, and thereafter activating a momentary control to activate a high flow, aspiration mode of operation and draw obstructive material into the distal end of the access catheter.

Abstract: An aspiration system exhibits an accelerated drop in negative pressure at the distal end of an aspiration catheter from the time of opening a valve. The system includes an aspiration pump in communication with a first chamber, and an aspiration catheter configured for placement into fluid communication with the first chamber by way of an elongate aspiration tube. A second chamber is provided between the aspiration tube and the catheter, and a valve is provided between the second chamber and the aspiration catheter. Upon opening of the valve with negative pressure at equilibrium in the first and second chambers, resistance to fluid flow between the second chamber and the distal end of the catheter is less than the resistance to fluid flow between the second chamber and the first chamber, causing a rapid aspiration into the second chamber.

Abstract: A split dilator aspiration system is disclosed. The system includes a catheter, having an elongate, flexible tubular body with a proximal end, a distal end, a side wall defining a central lumen, and a handle on the proximal end. A dilator is advanceable through the central lumen, the dilator having an elongate body, cannulated to receive a guidewire, and an axially extending split along at least a portion of the elongate body, configured to allow removal of a portion of the dilator laterally from the guidewire.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for implementing an integrated cloud system that enables a user to integrate software tasks executing on different software platforms. A method includes maintaining, by an integrated cloud system, a first software platform and a different second software platform that are configured to communicate by a shared networking subsystem. The integrated cloud system receives a first request to deploy instance(s) of a first software task on the first software platform. The first platform deploys the instance(s) of the first software tasks. The integrated cloud system receives a request to deploy instance(s) of a second software task on the second software platform. The second platform deploys the instance(s) of the second software task.

Abstract: A catheter has a cannulated guiding rail extending therethrough, an advance segment of the rail extending at least about 10 cm beyond the distal end of the catheter. The catheter and rail are advanced over a guidewire until the distal end of the advance segment is at a target vascular site. The catheter is thereafter advanced along the rail to the target vascular site.

Abstract: The present disclosure provides compositions and methods for treating ocular inflammation and ocular fibrosis and/or scarring using a cyclooxygenase 2 serine 516 acetylating agent alone or in combination with a cytosolic phospholipase A2 agonist.

Abstract: A large bore catheter has a guiding rail extending therethrough and an advance segment of the rail extends at least about 10 cm beyond the distal end of the catheter. The advance segment is advanced from the vena cava through the tricuspid and pulmonary valves of the heart into the central pulmonary artery while the distal end of the large bore catheter remains in the vena cava. The large bore catheter is thereafter distally advanced over the rail until the large bore catheter distal end is at least as far as the central pulmonary artery. The rail is thereafter proximally removed from the large bore catheter, and at least a portion of a clot is drawn from a pulmonary artery into the large bore catheter.

Abstract: A catheter has a cannulated guiding rail extending therethrough, an advance segment of the rail extending at least about 10 cm beyond the distal end of the catheter. The catheter and rail are advanced over a guidewire until the distal end of the advance segment is at a target vascular site. The catheter is thereafter advanced along the rail to the target vascular site.

Abstract: The distal tip of a sensing catheter is placed in proximity to a target intravascular foreign material. A signal is propagated from the sensing catheter, a return signal is received, and at least a portion of the foreign material is captured and removed when the return signal is indicative of a foreign material located within a capture zone.

Abstract: A system for accessing a central pulmonary artery includes an elongate, flexible tubular catheter, having a proximal end, a distal end and a catheter hub on the proximal end. An elongate, flexible rail has a proximal end, a distal end and a rail hub on the proximal end. The rail has a distal advance segment which extends at least about 10 cm beyond the distal end of the catheter when the catheter hub is adjacent the rail hub.

Abstract: Methods, systems, and techniques for generating a new anatomy use a processor to obtain a skin mesh of the new anatomy that is in correspondence with a skin mesh of a template anatomy; after obtaining the skin mesh, transfer a fascia mesh of the template anatomy to the new anatomy; and after the fascia mesh is transferred, generate a fat displacement field defining fat of the new anatomy. The displacement field includes multi-dimensional displacement vectors, and each of the displacement vectors relates a vertex of the skin mesh of the new anatomy to a corresponding vertex of the fascia mesh of the new anatomy. A new anatomy may also be generated by interpolating from anatomies in a database.

Abstract: Technology is described to provide a powered prosthetic wrist flexion device or elbow device. This device helps individuals with upper-limb loss to orient and position grasped objects.

Abstract: A weight training apparatus is configured to improve use and enjoyment of free-weights. The apparatus may leverage a modular or changeable assembly to accommodate different exercise or types of free-weight devices. The assembly may include a frame that can accommodate retainers that can secure to both a standard barbell shaft or receive plate weights. The retainers may also accommodate a handle that can rotate relative to the frame.

Abstract: Methods, systems, and techniques for generating a new, animation-ready anatomy. A skin mesh of the new anatomy is obtained, such as by performing a 3D depth scan of a subject. Selected template anatomies are also obtained, with each of those template anatomies having a skin mesh that corresponds with the new anatomy's skin mesh. The skin meshes of the new and selected template anatomies share a first pose. Each of the selected template anatomies also has a skeleton for the first pose and skinning weights, and the skin mesh in at least one additional pose that is different from the first pose and any other additional poses. The method then involves using a processor to interpolate, from the at least one of the skeleton and skinning weights of the selected template anatomies and the first and at least one additional pose of the selected template anatomies, the new anatomy.

Abstract: A transport bracket disclosed herein includes a support structure and vertical beams, which extend in a substantially vertical direction upward from opposing side of the support structure to form a substantially U-shapped channel configured to receive and support a door or similar sized object. A mounting plate extends horizontally from each beam, where one mounting plate is longer than the other. Each mounting plate defines an opening for receipt of a threaded vertical adjustment shaft extending through the opening. The vertical adjustment shaft has a top located vertically above the mounting plate, and a bottom located vertically below the mounting plate. A handle is operatively engaged to the top and a wheel assembly is engaged to the bottom. Rotation of the handle changes the proximity of the wheel assembly to the mounting plate. The wheel assembly has an axle extending from the vertical adjustment shaft, and at least one wheel rotatably engaged about the axle.

Abstract: A weight training apparatus is configured to improve use and enjoyment of free-weights. The apparatus may leverage a modular or changeable assembly to accommodate different exercise or types of free-weight devices. The assembly may include a frame that can accommodate retainers that can secure to both a standard barbell shaft or receive plate weights. The retainers may also accommodate a handle that can rotate relative to the frame.

Abstract: An invention regarding traffic management “Fast Lane On Warning” (FLOW) is disclosed whereby individual vehicles are informed and told what speed to go in order to pass through a traffic signal while the light is green. A converging, consolidating traffic managing “fast lane on warning” director sequencer works in conjunction with a traffic signal sequencer (commonly known in the art), both of which have the same service cycle period Pi. The (RGY) type phases and readout phases are set for each unique particular intersection. While the traffic sequencer controls repeating RGY cycles, the director sequencer instructs, generates, transmits repeating cycles of changeable readouts on one or more roadside unit (RSU) emplacements positioned up the road from the traffic signal for one or more lanes in one or more directions.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for deploying and using a light-weight cloud application platform. In one aspect, a method includes providing a deployment tool configured to deploy a light-weight cloud application platform in an execution environment in response to a user command that specifies the environment, and to create one or more instances of a cloud application executing on the light-weight cloud application platform in response to a user command that specifies a container image that includes the application. The deployment tool receives a first user command that specifies the execution environment. In response, the deployment tool deploys components of the light-weight cloud application platform, including a scheduling subsystem and a routing subsystem. The deployment tool receives a second user command that specifies a location of the container image.