Abstract: Certain processes for manufacturing an electrochemical sensor module include molding first and second opposing portions of a sensor module housing onto a carrier; installing an electrode arrangement on the first portion of the sensor module housing; folding the carrier to align the first portion of the sensor module housing with the second portion; and joining the first and second portions of the sensor module housing. The carrier can be advanced amongst different stations that perform the various process steps.

Abstract: Certain processes for manufacturing an electrochemical sensor module include assembly first and second housing portions of sensor modules; dispensing a sensor fiber across multiple first housing portions; joining the first and second housing portions; and separating the sensor modules by cutting the sensor fiber.

Abstract: Certain processes for manufacturing an electrochemical sensor module include molding first and second opposing portions of a sensor module housing onto a carrier; installing an electrode arrangement on the first portion of the sensor module housing; folding the carrier to align the first portion of the sensor module housing with the second portion; and joining the first and second portions of the sensor module housing. The carrier can be advanced amongst different stations that perform the various process steps.

Abstract: A sensor module includes a flexible linkage; an analysis cell housing; a member anchor; a piercing member; and an electrode arrangement. The analysis cell housing defines an analysis cell and a passageway providing access to the analysis cell from a sample port of the analysis cell housing. The member anchor is configured to move relative to the analysis cell housing along the axis defined by the passageway. The piercing member is configured to slide from a retracted position to an extended position when the member anchor is moved relative to the analysis cell housing. The electrode arrangement is arranged in fluid communication with the analysis cell housing.

Abstract: Certain embodiments of a sensor cartridge element include a sensor module, an electrode arrangement installed on the sensor module, and a delivery arrangement securely coupled to the sensor module. The sensor module includes an analysis cell and a skin piercing member. The electrode arrangement generates an electrical signal when exposed to a fluid sample collected in the analysis cell. The delivery arrangement includes a drug reservoir, a piston chamber, and a valve arrangement providing selective fluid communication between the drug reservoir and the piston chamber. Metering electronics and an actuator can manage collection of fluid samples and/or dispensing of drug doses.

Abstract: A sensor includes a sheath that is elongated along a longitudinal axis; a spacer positioned within the sheath and defining first and second channels having lengths that extend along the longitudinal axis; a first elongated member positioned within the first channel; and a second elongated member positioned within the second channel. The first elongated member includes an active surface forming a working electrode and the second elongated member including an active surface defining a counter electrode.

Abstract: The present disclosure relates to a sensor including an elongated member including at least a portion that is electrically conductive. The elongated member includes a sensing layer adapted to react with a material desired to be sensed. An insulating layer surrounds the elongated member. The insulating layer defines at least one access opening for allowing the material desired to be sensed to enter an interior region defined between the elongated member and the insulating layer. The insulating layer has an inner transverse cross-sectional profile that is different from an outer transverse cross-sectional profile of the elongated member. The difference in transverse cross-sectional profiles between the elongated member and the insulating layer provides channels at the interior region defined between the insulating layer and the elongated member. The channels extend generally along the length of the elongated member and are sized to allow the material desired to be sensed to move along the length of the sensor.

Abstract: The present disclosure relates to a sensor including a plurality of electrically conductive fibers. The sensor also includes a sensing material coating at least some of the fibers, and an insulating layer that surrounds the electrically conductive fibers.

Abstract: An in vivo electrochemical sensor including a working electrode, and an analyte-responsive sensing layer proximate the working electrode. The sensing layer is exposed at an edge of the sensor, wherein the sensor signal is limited, at least in part, by mass transport of analyte to the sensing layer. The sensor is configured and arranged for implantation into the body of a mammal for contact with body fluids of the mammal. The analyte diffuses to the sensing element via the edge of the sensor, thereby restricting mass transport of the analyte to the sensing element. This is because the solution-contacting surface area of the sensor edge is much smaller than an open face of the sensing layer.

Abstract: An in vivo electrochemical sensor including a working electrode, and an analyte-responsive sensing layer proximate the working electrode. The sensing layer is exposed at an edge of the sensor, wherein the sensor signal is limited, at least in part, by mass transport of analyte to the sensing layer. The sensor is configured and arranged for implantation into the body of a mammal for contact with body fluids of the mammal. The analyte diffuses to the sensing element via the edge of the sensor, thereby restricting mass transport of the analyte to the sensing element. This is because the solution-contacting surface area of the sensor edge is much smaller than an open face of the sensing layer.

Abstract: An in vivo electrochemical sensor including a working electrode, and an analyte-responsive sensing layer proximate the working electrode. The sensing layer is exposed at an edge of the sensor, wherein the sensor signal is limited, at least in part, by mass transport of analyte to the sensing layer. The sensor is configured and arranged for implantation into the body of a mammal for contact with body fluids of the mammal. The analyte diffuses to the sensing element via the edge of the sensor, thereby restricting mass transport of the analyte to the sensing element. This is because the solution-contacting surface area of the sensor edge is much smaller than an open face of the sensing layer.

Abstract: A reusable ceramic skin-piercing device. The skin-piercing device is capable of piercing the skin so as to make a sample of biological fluid available for an assay. In one embodiment, the skin-piercing device includes a skin-piercing element which is heated prior to use to a sufficiently high temperature to kill or deactivate pathogenic microorganisms. The device is heat-sterilized, being heated by passing an electrical current through a resistive element in thermal contact with the heat-conducting ceramic piercer. In another embodiment, the skin-piercing device includes a sleeve of elastomeric material with a sterilizing agent disposed in contact with the skin-piercing element. The sterilizing agent sterilizes the skin-piercing element after use. The skin-piercing element is made of a hard refractory ceramic material. The ceramic material is optionally a composite, for example, a composite of a ceramic material and a metal, or multiple ceramic materials.

Abstract: An apparatus for monitoring a level of a chemical species in a body fluid includes a fluid collection layer adapted for receiving the body fluid. The fluid collection layer is dry prior to being brought into contact with the body fluid. A catalyst is provided in, on, or near the fluid collection layer so as to be in contact with the body fluid in the fluid collection layer. The catalyst facilitates a reaction of the chemical species in the body fluid. An indicator, responsive to the reaction of the chemical species, is also provided in, on, or near the fluid collection layer. A characteristic of the indicator changes in response to the reaction of the chemical species, thereby indicating the level of the chemical species in the body fluid. This apparatus can be used, for example, to monitor the level of lactate in perspiration during activities, such as exercise or other athletic exertions.

Abstract: The present disclosure relates to a sensor including a bundle of electrically conductive fibers. The sensor also includes a sensing material coating at least some of the fibers in the bundle, and an insulating layer that surrounds the bundle of electrically conductive fibers.

Abstract: A reusable ceramic skin-piercing device. The skin-piercing device is capable of piercing the skin so as to make a sample of biological fluid available for an assay. In one embodiment, the skin-piercing device includes a skin-piercing element which is heated prior to use to a sufficiently high temperature to kill or deactivate pathogenic microorganisms. The device is heat-sterilized, being heated by passing an electrical current through a resistive element in thermal contact with the heat-conducting ceramic piercer. In another embodiment, the skin-piercing device includes a sleeve of elastomeric material with a sterilizing agent disposed in contact with the skin-piercing element. The sterilizing agent sterilizes the skin-piercing element after use.

Abstract: The present disclosure relates to an on-line lactate sensor arrangement. The sensor arrangement includes a lactate sensor, a catheter for withdrawing a test sample, and a first fluid flow line provided fluid communication between the lactate sensor and the catheter. The sensor arrangement also includes a source of sensor calibration and anticoagulant solution, and second fluid flow line providing fluid communication between the source of sensor calibration and anticoagulant solution and the lactate sensor.

Abstract: An integrated security cable, locking mechanism, and storage case particularly designed for locking skis, bicycles, snowboards, and similar articles to stationary objects such as trees and posts. The lock is employed by removing the lock and cable from the case. The cable is passed around the first object and back through an eye fitting. The annular storage case is so designed as to allow the cable end to pass into a center opening and coil around the interior wall of the case. The lock body then follows the cable into the center opening where it is retained by a snap fit between the lock mechanism and the case. The complete assembly is then easily carried in a jacket pocket or pouch.

Abstract: A universal indicator cap for a dishwasher rinse agent dispenser including a reservoir with an opening positioned in door of a dishwasher for indicating a low level of rinse agent in the reservoir, the door being pivotal between an opened horizontal position and a vertical closed position. The indicator cap comprises a body including a head portion having a cavity formed therein and a neck portion, a gasket adaptor positioned about the neck portion such that the indicator cap is adaptable to different models of the rinse agent dispenser, means for vertically mounting the body into the opening in the reservoir with the neck portion extending downwardly into a bottommost area of the reservoir, a first fluid passageway extending through the neck portion from an opened terminal end thereof to the cavity of the head portion, and a visual pump for pumping rinse agent through the first fluid passageway into the cavity to visually indicate the presence of the rinse agent in the cavity.

Abstract: The indicator cap for a dishwasher rinse agent reservoir comprising an elongated body having a head portion forming a cavity and a depending neck portion. The neck portion is operatively designed to sealingly engage the opening in the rinse agent reservoir. The neck portion comprises two fluid passageways extending from the lowermost tip of the neck portion, through the neck portion and into the cavity of the head portion.