Abstract: A compound, of formula (I): suitable for treating a cancer wherein the cancer is susceptible to inhibition of Cbl-B.

Abstract: This disclosure relates to compounds and methods of using said compounds, as well as pharmaceutical compositions containing such compounds, for treating diseases and conditions mediated by TEAD, such as cancer.

Abstract: This disclosure relates to compounds and methods of using said compounds, as well as pharmaceutical compositions containing such compounds, for treating diseases and conditions mediated by TEAD, such as cancer.

Abstract: Techniques are described for an autonomous vehicle to provide the autonomous vehicle's health-related information, identification information, and/or inspection information to a device that may be used by law enforcement or a government agency or a third-party so that the autonomous vehicle can comply with government regulations and can continue to operate on the road.

Abstract: A retainer resists decoupling of a first connector of a first cord from a second connector of a second cord. The retainer includes a first receiver having an adjuster to adjust the receiver about a portion of the first cord. The retainer includes a second receiver having an adjuster to adjust the receiver about a portion of the second cord. A connector housing couples the first and second receiver. The first receiver, second receiver, and connector housing form a continuous chamber in which lies portion of the first and second cords connected together when the retainer resides in an installed orientation. The retainer, in the installed orientation, resists incursion of water, dust particulate matter and other debris into the continuous chamber.

Abstract: Embodiments of the microwave amplification system are described. In an embodiment, a microwave amplification system includes a microwave amplifier that contains a paramagnetic material with an impurity. The impurity has a plurality of nuclear spin and electron spin-based energy levels. The system includes an input to receive a pumping signal which is transmitted to the microwave amplifier to cause a population inversion in the impurity and excite it to one of the nuclear spin and electron spin-based energy levels. The system further includes another input to receive an input signal to be amplified by the microwave amplifier, the input signal having a lower power than the pumping signal. Once transmitted to the microwave amplifier, the input signal is amplified by the excited state of the impurity in the microwave amplifier thereby generating an amplified signal.

Abstract: A method of additive manufacturing comprises operating an additive manufacturing system for fabricating a multiplicity of objects, while acquiring a set of images during fabrication of each of the objects. For each object, a respective set of images is analyzed to identify fabrication irregularities, and a fabrication score is generated based on the irregularities. The multiplicity of objects is clustered according to the fabrication scores into at least two clusters.

Abstract: Systems and methods for selecting content based on an event associated with a device identifier are provided. One or more processors can receive a request to serve content. The processors can identify a device identifier associated with the request. The processors can determine, from the device identifier, an event for which to serve content. The processors can determine, from the request, a length of time between a time the request to serve content is received and a time at which the event is scheduled to occur. The processors can select, based on the determined length of time and event parameters associated with the event, content for display and provide the selected content for display at a computing device associated with the device identifier.

Abstract: A vanity mirror assembly for a vehicle visor includes a housing having a support structure and a channel on a top side, a mirror connected to the support structure, and a light source disposed proximate the channel and operative to illuminate visible light. The vanity mirror assembly also includes at least one lens provided on the housing on at least one side of the mirror and operatively coupled to the light source, the at least one lens comprising a transparent optical element configured to refract the visible light from a front face of the at least one lens.

Abstract: Droplet interfaces are formed between droplets in an electro-wetting device comprising an array of actuation electrodes. Actuation signals are applied to selected actuation electrodes to place the droplets into an energised state in which the shape of the droplets is modified compared to a shape of the droplets in a lower energy state and to bring the two droplets into proximity. The actuation signals are then changed to lower the energy of the droplets into the lower energy state so that the droplets relax into the gap and the two droplets contact each other thereby forming a droplet interface. The use of sensing electrodes in the device permit electrical current measurements across the droplet interface. The sensing electrodes can be used for either (i) applying a reference signal during droplet actuation or (ii) recording electrical current measurements.

Abstract: A shelf assembly for an enclosure includes a shelf panel having an upper surface, a lower surface, and an edge extending between the upper and lower surfaces. The edge includes front, rear, and side edges. A light housing is coupled to the shelf panel and includes one or more walls defining an interior. The light housing includes front, rear, and side portions disposed adjacent to the front, rear, and side edges of the shelf panel, respectively. A plurality of light sources received within the light housing to project light outwardly therefrom.

Abstract: A shelf assembly for an enclosure includes a shelf panel and side brackets coupled to the shelf panel along respective lateral portions thereof. Each of the side brackets have a rear coupling portion configured to mount to structure of the enclosure.

Abstract: A shelving power supply system for an enclosure includes mounting structure of the enclosure having a positive terminal member and a negative terminal member and a shelf assembly including a side bracket for a shelf assembly having a coupling portion configured to engage the mounting structure to thereby mount the side bracket to the enclosure. The side bracket includes a first contact configured to electrically engage the positive terminal member of the mounting structure and a second contact configured to electrically engage the negative terminal member of the mounting structure when the side bracket is mounted thereto. An electrical component is coupled to the shelf assembly and electrically connected to the first contact and the second contact to receive power from the enclosure through the mounting structure.

Abstract: The disclosure relates to a valve assembly 10 for controlling a volute connecting opening 324 of a multi-channel turbine 500. The valve assembly 10 comprises a housing portion 300, a valve body 100 and an internal lever 200. The housing portion 300 defines a first volute channel 312, a second volute channel 314 and a volute connecting region 320. The housing portion 300 further comprises a cavity 340. The cavity 340 is separated from the volutes 312, 314 and can be accessed from outside the housing portion 300 via a housing opening 342 which extends from outside the housing portion 300 into the cavity 340. The volute connection region 320 is located between the first volute channel 312 and the second volute channel 314 and defines a volute connecting opening 324. The valve body 100 is inserted in the cavity 340 of the housing portion 300 and comprises at least one fin 120.

Abstract: Methods, systems, and media for aggregating and presenting content relevant to a particular video game. In some embodiments, the method comprises: identifying videos related to a video game; selecting videos relevant to each of a plurality of categories; selecting videos based on popularity; receiving a request to present a user interface related to the video game; determining user subscription information for a user associated with the request; selecting videos based on user subscription information; causing the user interface to be presented including representations of: videos relevant to a first category in a first portion, videos selected based on popularity in a second portion, and videos selected based on the user subscription information in a third portion; receiving a request to present a video selected via the user interface; and causing the user device to present the requested video.

Abstract: A launchpad is sized and shaped to accommodate an autonomous vehicle (AV) that includes at least one vehicle sensor. The launchpad includes one or more launchpad sensors located on or around the launchpad. A control subsystem receives launchpad sensor data from the launchpad sensor(s) and AV sensor data from the vehicle sensor(s). In response to the request for departure of the AV, the control subsystem determines, based at least in part upon the launchpad sensor data, whether the launchpad is free of obstructions that would prevent departure from the launchpad and determines, based at least in part upon the AV sensor data, whether the region in front of the AV is clear of obstructions that would prevent movement away from the launchpad. If both the launchpad and the region in front of the AV are free of obstructions, the AV is permitted to begin driving autonomously.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for distributing content based on context are disclosed. In one aspect, a method includes identifying, in a single resource, multiple different content item slots that are available for presentation of multiple different content items. A determination is made that a first content item slot is located in a first portion of the single resource, and that a second content item slot is located in a second different portion of the resource. A first content item is selected for presentation in the first content item slot based on terms that correspond to a first topic of the first portion of the resource. A second content item is selected for presentation in the second content item slot based on terms that correspond to a second topic of the second portion of the resource.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for distributing content based on context are disclosed. In one aspect, a method includes identifying, in a single resource, multiple different content item slots that are available for presentation of multiple different content items. A determination is made that a first content item slot is located in a first portion of the single resource, and that a second content item slot is located in a second different portion of the resource. A first content item is selected for presentation in the first content item slot based on terms that correspond to a first topic of the first portion of the resource. A second content item is selected for presentation in the second content item slot based on terms that correspond to a second topic of the second portion of the resource.

Abstract: Various lactam compound that binds Cbl-B, many of which are selective for Cbl-B over C-Cbl, and methods of making and using the same.

Abstract: Techniques are described for an autonomous vehicle to provide the autonomous vehicle's health-related information, identification information, and/or inspection information to a device that may be used by law enforcement or a government agency or a third-party so that the autonomous vehicle can comply with government regulations and can continue to operate on the road.