Abstract: Disclosed herein are compounds and compositions useful in the treatment of GLS1 mediated diseases, such as cancer, having the structure of Formula I: Methods of inhibition GLS1 activity in a human or animal subject are also provided.

Abstract: Methods, systems, and techniques for removal of PFAS contaminants from contaminated soil or sediment are provided. Example embodiments provide a water-based ex-situ method and system at a site that utilizes particle size and particle density segregation; deagglomeration, attrition, and retention time and sequential contacts with purified water; a recirculating water system with continual water treatment, and additional modules for destructive treatment of concentrated PFAS. In an example embodiment, the water treatment system of an example PFAS contaminant removal system and process includes ion exchange resin filtration component to remove PFAS effectively.

Abstract: Techniques are provided for generating an array-specific range of Tm values to be used for calling a sample in a given array positive or negative for a target nucleic acid sequence. A sample well in an array is provided with a control sample containing a control nucleic acid sequence. The control sample is amplified by thermal cycling the sample well. A Tm value for the control sample is identified and compared to an expected Tm value for the control nucleic acid sequence to calculate a relationship between the identified control Tm value and the expected control Tm value. By applying this relationship to an expected Tm value for a target nucleic acid sequence, an array-specific range of Tm values for the target nucleic acid sequence is generated and can be used for calling an experimental sample in the same array positive or negative for the target nucleic acid sequence.

Abstract: A segmented sealing assembly includes a first sealing segment and a second sealing segment, the first and second sealing segments having opposing mating components that are moved into a contact engagement to form the sealing assembly. The first and second sealing components include a first primary seal component on the first sealing component and a second primary seal component on the second sealing component that form a primary seal when the sealing segments are moved into the contact engagement. The sealing assembly includes compression elements on each of the first and second sealing segments. Compression of the compression elements exerts a force that moves the opposing mating components into the contact engagement. The mating components may be configured as tapered tongues having opposing slopes. A plurality of interlacing sealing beads may be provided on the tongues to provide a secondary seal within a gap between the tongues.

Abstract: A segmented sealing assembly includes a first sealing segment and a second sealing segment, the first and second sealing segments having opposing mating components that are moved into a contact engagement to form the sealing assembly. The first and second sealing components include a first primary seal component on the first sealing component and a second primary seal component on the second sealing component that form a primary seal when the sealing segments are moved into the contact engagement. The sealing assembly includes compression elements on each of the first and second sealing segments. Compression of the compression elements exerts a force that moves the opposing mating components into the contact engagement. The mating components may be configured as tapered tongues having opposing slopes. A plurality of interlacing sealing beads may be provided on the tongues to provide a secondary seal within a gap between the tongues.

Abstract: A personal table is provided having a table top supported by a support assembly. The table top is preferably constructed from blow-molded plastic and the support assembly preferably includes a first leg and a second leg that are pivotally connected. The legs desirably have a generally X-shaped configuration when the legs are placed in an upright position and the legs can be collapsed into a storage position. Each of the legs may include a lower portion, a body portion and an upper portion that is preferably selectively connected to the table top. The legs, for example, can be connected to the table top by inserting the upper portions of the legs into leg receiving recesses formed in the table top. The leg receiving recesses are preferably integrally formed in the bottom surface of the table top as part of a one-piece construction.

Abstract: The present invention relates to a method for determining dangerous or pesticidal residues in plastics, which comprises processing a plastic sample to a fine powder, converting the powder into a form accessible for determining the analyte, and determining the analyte. The present invention is thus concerned with the analysis of plastics, in particular trace analysis of residues in plastics. The method advantageously allows the use of microextraction techniques and thus a high sample throughput. The method is especially useful for determining whether or not a plastic sample such as agricultural waste plastics contain pesticidal residues.

Abstract: A method and system for removing contaminants from contaminated soil at a site utilizes particle size segregation and particle density segregation to yield a plurality of fractions, whereby each of the fractions are tested and identified for the presence of unacceptable levels of contaminants, and the soil fractions from the contaminated soil at the site corresponding to the identified contaminated fractions are collected for subsequent disposal or treatment, while the remaining untainted soil fractions are homogenized and returned to the site.

Abstract: A personal table is provided having a table top supported by a support assembly. The table top is preferably constructed from blow-molded plastic and the support assembly preferably includes a first leg and a second leg that are pivotally connected. The legs desirably have a generally X-shaped configuration when the legs are placed in an upright position and the legs can be collapsed into a storage position. Each of the legs may include a lower portion, a body portion and an upper portion that is preferably selectively connected to the table top. The legs, for example, can be connected to the table top by inserting the upper portions of the legs into leg receiving recess formed in the table top. The leg receiving recesses are preferably integrally formed in the bottom surface of the table top as part of a one-piece construction.

Abstract: A method and system for removing contaminants from contaminated soil at a site utilizes particle size segregation and particle density segregation to yield a plurality of fractions, whereby each of the fractions are tested and identified for the presence of unacceptable levels of contaminants, and the soil fractions from the contaminated soil at the site corresponding to the identified contaminated fractions are collected for subsequent disposal or treatment, while the remaining untainted soil fractions are homogenized and returned to the site.

Abstract: A personal table is provided having a table top supported by a support assembly. The table top is preferably constructed from blow-molded plastic and the support assembly preferably includes a first leg and a second leg that are pivotally connected. The legs desirably have a generally X-shaped configuration when the legs are placed in an upright position and the legs can be collapsed into a storage position. Each of the legs may include a lower portion, a body portion and an upper portion that is preferably selectively connected to the table top. The legs, for example, can be connected to the table top by inserting the upper portions of the legs into leg receiving recesses formed in the table top. The leg receiving recesses are preferably integrally formed in the bottom surface of the table top as part of a one-piece construction.

Abstract: A display assembly including an upper channel, a lower channel and a plurality of display panels. The upper channel includes longitudinal first and second upper tracks oriented parallel and disposed immediately adjacent. The lower channel is disposed substantially vertically aligned with the upper channel and includes a longitudinal first lower track and a plurality of stall sets oriented substantially transverse to the first lower track such that each stall had an open end for communication with the first lower track. The display panels engage the upper and lower channels and include a frame and covering. The frame engages the upper and lower channels with a plurality of top and bottom guide elements. The covering is configured generally equivalent to a periphery of the frame and has an exterior surface for bearing at least a portion of a graphical representation.

Abstract: A display assembly including an upper channel, a lower channel and a plurality of display panels. The upper channel includes longitudinal first and second upper tracks oriented parallel and disposed immediately adjacent. The lower channel is disposed substantially vertically aligned with the upper channel and includes a longitudinal first lower track and a plurality of stall sets oriented substantially transverse to the first lower track such that each stall had an open end for communication with the first lower track. The display panels engage the upper and lower channels and include a frame and covering. The frame engages the upper and lower channels with a plurality of top and bottom guide elements. The covering is configured generally equivalent to a periphery of the frame and has an exterior surface for bearing at least a portion of a graphical representation.

Abstract: Ceiling and wall panel clip assemblies are characterized by wall and ceiling panel clips having extending fingers that engage companion U-shaped spring-steel panel clips attached to various panels for securing the panels to a framework or grid on the wall or ceiling of a structure. The ceiling panel clip includes a main tee characterized by a main tee leg, typically fitted with a top cross member and a bottom cross member and extending downwardly to a finger mount that mounts the three fingers which engage the corresponding panel clips in a friction-fit. In one embodiment the ceiling panel clips accommodate a support clip fitted over the top of the main tee at the top cross member and having a flange and a downwardly-extending leg attached to a lanyard secured to a decorative ceiling panel, for safety purposes. The wall panel clips include a finger mount flange for supporting the three outwardly-extending panel fingers that engage the companion panel clips attached to selected wall panels.

Abstract: A personal table is provided having a table top supported by a support assembly. The table top is preferably constructed from blow-molded plastic and the support assembly preferably includes a first leg and a second leg that are pivotally connected. The legs desirably have a generally X-shaped configuration when the legs are placed in an upright position and the legs can be collapsed into a storage position. Each of the legs may include a lower portion, a body portion and an upper portion that is preferably selectively connected to the table top. The legs, for example, can be connected to the table top by inserting the upper portions of the legs into leg receiving recess formed in the table top. The leg receiving recesses are preferably integrally formed in the bottom surface of the table top as part of a one-piece construction.

Abstract: A personal table is provided having a table top supported by a support assembly. The table top is preferably constructed from blow-molded plastic and the support assembly preferably includes a first leg and a second leg that are pivotally connected. The legs desirably have a generally X-shaped configuration when the legs are placed in an upright position and the legs can be collapsed into a storage position. Each of the legs may include a lower portion, a body portion and an upper portion that is preferably selectively connected to the table top. The legs, for example, can be connected to the table top by inserting the upper portions of the legs into leg receiving recess formed in the table top. The leg receiving recesses are preferably integrally formed in the bottom surface of the table top as part of a one-piece construction.

Abstract: Sealing gasket construction for providing a fluid seal intermediate a pair of opposed, mating parts or structures. The gasket includes a metal retainer and a resilient seal element received in a groove portion formed between sections of the retainer.