Patents by Inventor Jayarama K. Shetty

Jayarama K. Shetty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SACCHARIFICATION ENZYME COMPOSITION AND METHOD OF SACCHARIFICATION THEREOF
    Publication number: 20090305360
    Abstract: The present disclosure relates to a Bacillus subtilis alpha-amylase (AmyE) or its variants thereof. AmyE or its variants thereof may be used to more efficiently produce fermentable sugars from starch. Also disclosed are a composition comprising a glucoamylase and AmyE or variant thereof and a method of processing starch utilizing the described enzyme composition.
    Type: Application
    Filed: June 4, 2009
    Publication date: December 10, 2009
    Inventors: Suzanne BRENEMAN, Sung Ho LEE, Vivek SHARMA, Jayarama K. SHETTY
  • ALPHA-AMYLASE VARIANTS WITH ALTERED PROPERTIES
    Publication number: 20090252828
    Abstract: Disclosed are compositions comprising variants of alpha-amylase that have alpha-amylase activity and which exhibit altered properties relative to a parent AmyS-like alpha-amylase from which they are derived. The compositions comprise an additional enzyme such as a phytase. Also disclosed are methods of using the compositions, and kits related thereto.
    Type: Application
    Filed: November 3, 2008
    Publication date: October 8, 2009
    Applicant: Danisco US Inc., Genencor Division
    Inventors: Luis G. Cascao-Pereira, James T. Kellis, JR., Bradley A. Paulson, Scott D. Power, Sandra W. Ramer, Vivek Sharma, Andrew Shaw, Jayarama K. Shetty, Donald E. Ward
  • GLUCOAMYLASE AND BUTTIAUXIELLA PHYTASE DURING SACCHARIFICATION
    Publication number: 20090246845
    Abstract: Described are compositions and methods relating to the use of a glucoamylase in combination with a phytase in starch processing to reduce the levels of phytic acid in end-products.
    Type: Application
    Filed: March 9, 2009
    Publication date: October 1, 2009
    Inventors: SUZANNE BRENEMAN, ORESTE J. LANTERO, JR., BRADLEY A. PAULSON, JAYARAMA K. SHETTY
  • VARIANTS OF BACILLUS LICHENIFORMIS ALPHA-AMYLASE WITH INCREASED THERMOSTABILITY AND/OR DECREASED CALCIUM DEPENDENCE
    Publication number: 20090238923
    Abstract: Variants of B. licheniformis alpha-amylase exhibit improved enzymatic performance, including increased themostability and reduced calcium dependence. Compositions comprising the variants are useful in methods of starch processing, starch liquefaction, fermatation, starch saccharification, cleaning, laundrying, textile desizing, baking, and biofilm removal. The nucleic acids encoding the variants are also disclosed.
    Type: Application
    Filed: November 3, 2008
    Publication date: September 24, 2009
    Applicant: Danisco US Inc., Genencor Division
    Inventors: Andrew SHAW, Sandra W. Ramer, Scott D. Power, Jayarama K. Shetty, Bradley A. Paulson, Vivek Sharma, Donald Ward
  • ph Adjustment Free System For Producing Fermentable Sugars and Alcohol
    Publication number: 20090215127
    Abstract: The present invention relates to a process for producing downstream products, such as fermentable sugars (e.g., glucose) and alcohols (e.g., ethanol) from starch-containing material (e.g., grain) without a pH adjustment before or after the starch liquefaction step.
    Type: Application
    Filed: February 5, 2009
    Publication date: August 27, 2009
    Applicant: DANISCO US INC., GENENCOR DIVISION
    Inventors: Suzanne Breneman, Brad A. Paulson, Vivek Sharma, Jayarama K. Shetty
  • Expression of Granular Starch Hydrolyzing Enzymes in Trichoderma and process for producing glucose from granular starch substrates
    Publication number: 20090203087
    Abstract: The present invention relates to filamentous fungal host cells and particularly Trichoderma host cells useful for the production of heterologous granular starch hydrolyzing enzymes having glucoamylase activity (GSHE). Further the invention relates to a method for producing a glucose syrup comprising contacting a granular starch slurry obtained from a granular starch substrate simultaneously with an alpha amylase and a GSHE at a temperature equal to or below the gelatinization temperature of the granular starch to obtain a composition of a glucose syrup.
    Type: Application
    Filed: October 19, 2007
    Publication date: August 13, 2009
    Inventors: Toby M. Baldwin, Benjamin S. Bower, Gopal K. Chotani, Nigel Dunn-Coleman, Oreste J. Lantero, JR., Suzanne E. Lantz, Michael J. Pepsin, Jayarama K. Shetty, Bruce A. Strohm
  • ENZYME BLENDS FOR FERMENTATION
    Publication number: 20090203101
    Abstract: The present invention relates to an enzyme blend composition comprising a glucoamylase, an acid stable alpha amylase, and an acid fungal protease. The present invention is further directed to a method for producing end products such as alcohols from fermentable sugars, comprising the steps of: (a) contacting a slurry comprising a milled grain that contains starch with an alpha amylase to produce a liquefact; (b) contacting the liquefact with a glucoamylase, an acid stable alpha amylase, and an acid fungal protease, to produce fermentable sugars; and (c) fermenting the fermentable sugars in the presence of a fermenting organism to produce end products.
    Type: Application
    Filed: October 14, 2008
    Publication date: August 13, 2009
    Inventors: Suzanne Breneman, Oreste J. Lantero, JR., Jayarama K. Shetty
  • Acid fungal protease in fermentation of insoluble starch substrates
    Patent number: 7563607
    Abstract: The invention is directed to methods of producing ethanol and decreasing residual starch production in a no cook fermentation comprising contacting granular starch containing substrates with a granular starch hydrolyzing enzyme, a protease, and a fermenting microorganism under suitable fermentation conditions at a temperature below the starch gelatinization temperature of the starch substrate to produce ethanol, wherein the ethanol production is increased and the amount of residual starch is decreased compared to a substantially similar method conducted without the protease.
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: July 21, 2009
    Assignee: Genencor International, Inc.
    Inventors: Gang Duan, Nigel Dunn-Coleman, Oreste Lantero, Craig E. Pilgrim, Jayarama K. Shetty
  • METHODS FOR PRODUCING END-PRODUCTS FROM CARBON SUBSTRATES
    Publication number: 20090181433
    Abstract: The present invention provides means for the production of desired end-products of in vitro and/or in vivo bioconversion of biomass-based feed stock substrates, including but not limited to such materials as starch and cellulose. In particularly preferred embodiments, the methods of the present invention do not require gelatinization and/or liquefaction of the substrate.
    Type: Application
    Filed: October 2, 2008
    Publication date: July 16, 2009
    Applicant: GENENCOR INTERNATIONAL, INC.
    Inventors: Gopal K. Chotani, Manoj Kumar, Jeffrey P. Pucci, Karl J. Sanford, Jayarama K. Shetty
  • Starch Hydrolysis Using Phytase with an Alpha Amylase
    Publication number: 20080299622
    Abstract: The present invention relates to a method for liquefying starch comprising contacting a slurry of a starch substrate with an enzyme composition comprising a phytase and an alpha amylase. The invention also relates to an enzyme mixture comprising a phytase derived from Buttiauxella sp. and variants thereof and an alpha amylase.
    Type: Application
    Filed: February 6, 2008
    Publication date: December 4, 2008
    Inventors: Bradley A. Paulson, Scott D. Power, Sandra W. Ramer, Jayarama K. Shetty, Donald E. Ward
  • Truncated forms of pullulanase
    Patent number: 7449320
    Abstract: The present invention relates to modified pullulanases useful in the starch industry. The present invention provides methods for producing the modified pullulanase, enzymatic compositions comprising the modified pullulanase, and methods for the saccharification of starch comprising the use of the enzymatic compositions.
    Type: Grant
    Filed: March 3, 1999
    Date of Patent: November 11, 2008
    Assignee: Genencor International, Inc.
    Inventors: Brian S. Miller, Jayarama K. Shetty
  • Cleaning compositions comprising transglucosidase
    Publication number: 20080229514
    Abstract: Provided herein is a composition comprising: a) a transglucosidase enzyme; and b) a natural gum polysaccharide, wherein said natural gum polysaccharide is a substrate for said transglucosidase enzyme. A method of using a transglucosidase enzyme to a degrade natural gum polysaccharide is also provided. The composition and method may be employed in cleaning applications.
    Type: Application
    Filed: March 22, 2007
    Publication date: September 25, 2008
    Inventors: Ayrookaran J. Poulose, Hugh C. McDonald, Jayarama K. Shetty
  • Aspergillus Kawachi Acid-Stable Alpha Amylase and Applications in Granular Starch Hydrolysis
    Publication number: 20080199927
    Abstract: The present invention relates to a method for producing an end product and particularly an alcohol which comprises contacting a granular starch substrate with an acid-stable alpha amylase (asAA) having granular starch hydrolyzing (GSH) activity and a glucoamylase (GA) in a fermentation step which also comprises ethanologenic microorganisms at a temperature between about 25 to 65° C. and producing an end-product.
    Type: Application
    Filed: May 24, 2005
    Publication date: August 21, 2008
    Inventors: Nigel Dunn-Coleman, Susan M. Fiske, Oreste J. Lantero, Suzanne E. Lantz, Michael J. Pepsin, Jayarama K. Shetty
  • Modified forms of pullulanase
    Patent number: 7399623
    Abstract: The present invention relates to modified pullulanases useful in the starch industry. The present invention provides methods for producing the modified pullulanase, enzymatic compositions comprising the modified pullulanase, and methods for the saccharification of starch comprising the use of the enzymatic compositions.
    Type: Grant
    Filed: September 16, 2002
    Date of Patent: July 15, 2008
    Assignee: Genencor International, Inc.
    Inventors: Brian S. Miller, Jayarama K. Shetty
  • Acid-Stable Alpha Amylases having Granular Starch Hydrolyzing Activity and Enzyme Compositions
    Publication number: 20080153136
    Abstract: The present invention relates to an acid-stable alpha amylase (asAA) derived from a strain of Aspergillus kawachi, which has granular starch hydrolyzing (GSH) activity, the heterologous expression of the asAA having GSH activity in filamentous fungal host cells and enzyme compositions including the same which optionally include glucoamylase.
    Type: Application
    Filed: January 30, 2008
    Publication date: June 26, 2008
    Inventors: Nigel Dunn-Coleman, Susan M. Fiske, Suzanne E. Lantz, Paulien Neefe-Kruithof, Michael J. Pepsin, Jayarama K. Shetty
  • Process for hydrolyzing starch without pH adjustment
    Publication number: 20080145900
    Abstract: An alpha-amylase enzyme obtained from Bacillus acidocaldarius species is utilized to liquefy starch at a pH as low as 3.0 without the need to add thermostabilizing agents such as calcium. The alpha-amylase produces acceptable DE yields in a single liquefaction step and does not need to be inactivated prior to conducting saccharification which can proceed without adjustment of the pH of the liquefact. Alternatively, a secondary liquefaction process can be utilized, in which case two additions of the alpha-amylase are used resulting in a combined low dosage of the enzyme.
    Type: Application
    Filed: February 20, 2008
    Publication date: June 19, 2008
    Inventors: Jayarama K. Shetty, Eric C. Singley, Bruce A. Strohm
  • Acid-stable alpha amylases having granular starch hydrolyzing activity and enzyme compositions
    Patent number: 7354752
    Abstract: The present invention relates to an acid-stable alpha amylase (asAA) derived from a strain of Aspergillus kawachi, which has granular starch hydrolyzing (GSH) activity, the heterologous expression of the asAA having GSH activity in filamentous fungal host cells and enzyme compositions including the same which optionally include glucoamylase.
    Type: Grant
    Filed: May 24, 2005
    Date of Patent: April 8, 2008
    Assignee: Genencor International, Inc.
    Inventors: Nigel Dunn-Coleman, Susan M. Fiske, Suzanne E. Lantz, Paulien Neefe-Kruithof, Michael J. Pepsin, Jayarama K. Shetty
  • Process for conversion of granular starch to ethanol
    Publication number: 20070281344
    Abstract: The present invention concerns a method of producing glucose from a granular starch substrate comprising, contacting a slurry comprising granular starch obtained from plant material with an alpha-amylase at a temperature below the starch gelatinization temperature of the granular starch to produce oligosaccharides and hydrolyzing the oligosaccharides to produce a mash comprising at least 20% glucose and further comprising fermenting the mash to obtain ethanol.
    Type: Application
    Filed: June 6, 2006
    Publication date: December 6, 2007
    Inventors: Oreste J. Lantero, Mian Li, Jayarama K. Shetty
  • Expression of granular starch hydrolyzing enzymes in and process for producing glucose from granular starch substrates
    Patent number: 7303899
    Abstract: The present invention relates to filamentous fungal host cells and particularly Trichoderma host cells useful for the production of heterologous granular starch hydrolyzing enzymes having glucoamylase activity (GSHE). Further the invention relates to a method for producing a glucose syrup comprising contacting a granular starch slurry obtained from a granular starch substrate simultaneously with an alpha amylase and a GSHE at a temperature equal to or below the gelatinization temperature of the granular starch to obtain a composition of a glucose syrup.
    Type: Grant
    Filed: November 18, 2004
    Date of Patent: December 4, 2007
    Assignee: Genencor International, Inc.
    Inventors: Toby M. Baldwin, Benjamin S. Bower, Gopal K. Chotani, Nigel Dunn-Coleman, Oreste J. Lantero, Jr., Suzanne E. Lantz, Michael J. Pepsin, Jayarama K. Shetty, Bruce A. Strohm
  • Heterologous expression of an acid-stable alpha amylase and applications in granular starch hydrolysis
    Patent number: 7037704
    Abstract: The present invention relates to a granular starch hydrolyzing enzyme composition comprising an acid stable alpha amylase (asAA) having granular starch hydrolyzing activity. The invention also relates to a one-step method for producing an alcohol which comprises contacting a granular starch substrate with an acid-stable alpha amylase (asAA) having granular starch hydrolyzing (GSH) activity and a glucoamylase (GA) in a fermentation step which also comprises ethanologenic microorganisms at a temperature of 25–40° C. to obtain a fermentation broth having 5 to 20% ethanol.
    Type: Grant
    Filed: November 30, 2004
    Date of Patent: May 2, 2006
    Assignee: Genencor International, Inc.
    Inventors: Nigel Dunn-Coleman, Oreste J. Lantero, Jr., Suzanne E. Lantz, Michael J. Pepsin, Jayarama K. Shetty