Abstract: The disclosed technology generally relates to a tire and more particularly to a non-pneumatic tire. The non-pneumatic tire that has maneuverability similar to a pneumatic tire even without using air pressure, and can support the load of a vehicle and can guide performance-oriented tire deformation behavior by using a meta structure. In an aspect, a non-pneumatic tire includes a tread that comes in contact with the ground, a rim that is connected with an axle, and a spoke unit that serves as a structural support between the rim and the tread, in which the spoke unit is formed in a meta structure in which unit structures are repeated.

Abstract: A display apparatus for and a method of providing to users additional information associated with a broadcasting signal that is being output via the display apparatus are provided. The display apparatus includes a communication unit configured to perform data communication, and a control unit configured to acquire a keyword from content being reproduced by the display apparatus, to acquire user preference information corresponding to a mobile terminal, to acquire a search result corresponding to the acquired keyword, to produce additional information based on the acquired search result and the acquired user preference information, and to provide the additional information to the mobile terminal via the communication unit.

Abstract: Disclosed are a main image processing apparatus, a sub image processing apparatus and a control method thereof. The control method of the sub image processing apparatus includes receiving a user's touch input through the sub image processing apparatus; determining which contents correspond to a touched area where the touch input occurs; sensing change in location of the touch input; and transmitting a control command for the contents to the main image processing apparatus in response to the sensed change in the location of the touch input. With this, it is more convenient for a user to control the main image processing apparatus through the sub image processing apparatus supporting the touch input.

Abstract: The disclosed technology generally relates to a tire, and more particularly to a non-pneumatic tire that has handling performance similar to a pneumatic tire, supports the load of a vehicle and improves riding comfort by employing a parametric structure. In one aspect, a non-pneumatic tire includes a tread that comes in contact with the ground, a rim that is connected with an axle, and a spoke unit that functions as a structural support between the rim and the tread, in which the spoke unit is formed by circularly arranging spokes. The spokes have a single closed-loop longitudinal cross-section circumscribed to the rim and around the center of the tire.

Abstract: Disclosed are a main image processing apparatus, a sub image processing apparatus and a control method thereof. The control method of the sub image processing apparatus includes receiving a user's touch input through the sub image processing apparatus; determining which contents correspond to a touched area where the touch input occurs; sensing change in location of the touch input; and transmitting a control command for the contents to the main image processing apparatus in response to the sensed change in the location of the touch input. With this, it is more convenient for a user to control the main image processing apparatus through the sub image processing apparatus supporting the touch input.

Abstract: Disclosed are a main image processing apparatus, a sub image processing apparatus and a control method thereof. The control method of the sub image processing apparatus includes receiving a user's touch input through the sub image processing apparatus; determining which contents correspond to a touched area where the touch input occurs; sensing change in location of the touch input; and transmitting a control command for the contents to the main image processing apparatus in response to the sensed change in the location of the touch input. With this, it is more convenient for a user to control the main image processing apparatus through the sub image processing apparatus supporting the touch input.

Abstract: The present invention provides MEL-18, which is a biomarker for human epidermal growth factor receptor2 (HER2)-positive cancer and anti-HER2 therapy, and a use thereof. According to the present invention, MEL-18 is a prognostic factor or predictor for a response of subjects to an anti-HER2-targeted drug in HER2-POSITIVE cancer and may be used in companion diagnostics for HER2-targeted drugs in subjects with HER2-positive cancer. Therefore, HER2-positive cancer may be more effectively treated by overcoming resistance to HER2 therapeutic agents and enhancing therapeutic efficacy by determining whether ADAM10/17 inhibitors are administered or co-administered with HER2-targeted drugs.

Abstract: A function of cyclin-dependent kinase 12 (CDK12) as a biomarker for a human epidermal growth factor receptor 2 (HER2)-positive cancer and anti-HER2 therapy, and a use of the CDK12 are provided. The CDK12 may be used for companion diagnostics of a HER2-targeted therapeutic agent for a subject having HER2+ cancer as a prognostic factor and a predictive factor for response of the subject to the anti-HER2-targeted therapeutic agent in HER2+ cancer, or used to check the probability of expressing resistance to the HER2-targeted therapeutic agent. When the CDK12 is amplified or expressed at a level higher than a reference value, the CDK12 may be suppressed to overcome the resistance to the HER2 therapeutic agent and improve a therapeutic effect, thereby improving the therapeutic efficiency of HER2-positive cancer.

Abstract: The disclosed technology generally relates to a tire and more particularly to a non-pneumatic tire. The non-pneumatic tire that has maneuverability similar to a pneumatic tire even without using air pressure, and can support the load of a vehicle and can guide performance-oriented tire deformation behavior by using a meta structure. In an aspect, a non-pneumatic tire includes a tread that comes in contact with the ground, a rim that is connected with an axle, and a spoke unit that serves as a structural support between the rim and the tread, in which the spoke unit is formed in a meta structure in which unit structures are repeated.

Abstract: The disclosed technology generally relates to a tire, and more particularly to a non-pneumatic tire that has handling performance similar to a pneumatic tire, supports the load of a vehicle and improves riding comfort by employing a parametric structure. In one aspect, a non-pneumatic tire includes a tread that comes in contact with the ground, a rim that is connected with an axle, and a spoke unit that functions as a structural support between the rim and the tread, in which the spoke unit is formed by circularly arranging spokes. The spokes have a single closed-loop longitudinal cross-section circumscribed to the rim and around the center of the tire.

Abstract: The present invention relates to a novel pyrimidine-4-carboxylic acid derivative having an anticancer activity, and the compound thereof is useful as a drug for treating and preventing tumor diseases, wherein the compound is represented by the Formula 1: or a pharmaceutically acceptable salt thereof, wherein: Q is a C6-C15 aryl group; or a C4-C13 heteroaryl group, wherein the heteroaryl contains 1, 2 or 3 heteroatoms substituted with 1-3 heteroatom(s) selected from the group consisting of nitrogen, oxygen or sulfur; R is a halogen; a C1-C10 haloalkyl substituted with 1-13 halogen atom(s); a C1-C10 alkoxy; a 5- or 6-membered heterocycloalkyl or (CH2)r-R1 wherein the heterocycloalkyl contains 1-2 heteroatom(s) selected from the group consisting of nitrogen and oxygen; R1 is a hydrogen; a C1-C10 alkoxy; amino; mono(C1-C10 alkyl)amino; di(C1-C10 alkyl)amino; or —NHC(O)-phenyl; n is 1, 2, 3, 4, 5, or 6; and r is 0, 1, 2, 3, 4, 5, or 6; and m is 0, 1, 2 or 3.

Abstract: A display apparatus for and a method of providing to users additional information associated with a broadcasting signal that is being output via the display apparatus are provided. The display apparatus includes a communication unit configured to perform data communication, and a control unit configured to acquire a keyword from content being reproduced by the display apparatus, to acquire user preference information corresponding to a mobile terminal, to acquire a search result corresponding to the acquired keyword, to produce additional information based on the acquired search result and the acquired user preference information, and to provide the additional information to the mobile terminal via the communication unit.

Abstract: A display apparatus for and a method of providing to users additional information associated with a broadcasting signal that is being output via the display apparatus are provided. The display apparatus includes a communication unit configured to perform data communication, and a control unit configured to acquire a keyword from content being reproduced by the display apparatus, to acquire user preference information corresponding to a mobile terminal, to acquire a search result corresponding to the acquired keyword, to produce additional information based on the acquired search result and the acquired user preference information, and to provide the additional information to the mobile terminal via the communication unit.

Abstract: A display apparatus for and a method of providing to users additional information associated with a broadcasting signal that is being output via the display apparatus are provided. The display apparatus includes a communication unit configured to perform data communication, and a control unit configured to acquire a keyword from content being reproduced by the display apparatus, to acquire user preference information corresponding to a mobile terminal, to acquire a search result corresponding to the acquired keyword, to produce additional information based on the acquired search result and the acquired user preference information, and to provide the additional information to the mobile terminal via the communication unit.

Abstract: The present invention relates to a novel pyrimidine-4-carboxylic acid derivative having an anticancer activity, and the compound of the present invention is useful as a drug for treating and preventing tumor diseases.

Abstract: A display apparatus for and a method of providing to users additional information associated with a broadcasting signal that is being output via the display apparatus are provided. The display apparatus includes a communication unit configured to perform data communication, and a control unit configured to acquire a keyword from content being reproduced by the display apparatus, to acquire user preference information corresponding to a mobile terminal, to acquire a search result corresponding to the acquired keyword, to produce additional information based on the acquired search result and the acquired user preference information, and to provide the additional information to the mobile terminal via the communication unit.

Abstract: A method for providing Graphical User Interface (GUI) for selecting a broadcast channel, and a broadcast receiving apparatus having the same are provided. The GUI for selecting a broadcast channel includes a keypad having a pointer to be moved by manipulation of a user on a remote control apparatus and keys selectable by the pointer, and then the user is able to input a preferred broadcast channel by using the keypad and the pointer. Accordingly, the user is able to input a preferred broadcast channel without using the number keys, so the number keys may be omitted in the remote control apparatus. As a result, miniaturization of the remote control apparatus is possible.

Abstract: An image processing apparatus comprises a UI generating part to generate a first user interface including at least one UI menu item to select a function; a user input part to receive a user instruction to adjust a size of the UI menu item; and a controller to control the UI generating part to increase or decrease the size of the UI menu item of the first user interface depending on the user instruction, and display the UI menu item with the increased or decreased size.

Abstract: A method for providing Graphical User Interface (GUI) for selecting a broadcast channel, and a broadcast receiving apparatus having the same are provided. The GUI for selecting a broadcast channel includes a keypad having a pointer to be moved by manipulation of a user on a remote control apparatus and keys selectable by the pointer, and then the user is able to input a preferred broadcast channel by using the keypad and the pointer. Accordingly, the user is able to input a preferred broadcast channel without using the number keys, so the number keys may be omitted in the remote control apparatus. As a result, miniaturization of the remote control apparatus is possible.

Abstract: A method for providing Graphical User Interface (GUI) for selecting a broadcast channel, and a broadcast receiving apparatus having the same are provided. The GUI for selecting a broadcast channel includes a keypad having a pointer to be moved by manipulation of a user on a remote control apparatus and keys selectable by the pointer, and then the user is able to input a preferred broadcast channel by using the keypad and the pointer. Accordingly, the user is able to input a preferred broadcast channel without using the number keys, so the number keys may be omitted in the remote control apparatus. As a result, miniaturization of the remote control apparatus is possible.