Abstract: A telescopic adapter device for a dredging machine includes a protective cover at an exit of a flexible shaft of a dredging machine, a connector detachably connected to the protective cover, a flexible shaft conduit with an inner end fixed in an inner hole of the connector, and a sliding conduit sleeved on an outer wall of the flexible shaft conduit, where the sliding conduit includes an inner end provided with a clamping joint for clamping the flexible shaft conduit, and an outer end provided with a bending portion; and a rubber jacket is sleeved on an outer wall of the bending portion. The telescopic adapter device for a dredging machine not only can prevent damage to a glazed surface at a corner of a toilet, but also improves a turning capacity of the flexible shaft.

Abstract: Disclosed are compounds inhibiting the conversion of ?-KG to D-2-HG, pharmaceutically acceptable salts, hydrates, solvates or stereoisomers thereof and pharmaceutical compositions comprising the compounds. The compound and the pharmaceutical composition can effectively treat IDH associated diseases, including cancer.

Abstract: A word completion method and apparatus are described. The method is applied to a search scenario and is used to complete an incomplete word entered by a user. The method is based on an improved trie. Hot words are stored in some nodes of the trie. In the word completion method, a target node that matches a character string is searched in the trie, and at least one completed word is output to a user based on a hot word stored in the target node. Word completion efficiency is improved, and a case in which a word is recommended to a user when the user enters an excessively short character string is avoided.

Abstract: A display apparatus is disclosed in the embodiments of the present disclosure. The display apparatus includes a display structure, a sound emitting substrate, and a plurality of electromagnetic exciters; wherein the display structure is configured to receive and display optical signals; the sound emitting substrate is attached to the display structure and is divided into a plurality of regions by a plurality of isolation zones, at least some of the plurality of regions are attached to at least one of the plurality of electromagnetic exciters; and the plurality of electromagnetic exciters are configured to generate bending waves at an area where the plurality of electromagnetic exciters are attached to the sound emitting substrate.

Abstract: A display apparatus and a method for processing audio are provided, the display apparatus includes a circuit board provided with a hybrid circuit, a filter circuit and a speaker; the hybrid circuit is configured to receive an original audio signal and superpose a first sub-signal of the original audio signal on a second sub-signal of the original audio signal to obtain a hybrid audio signal; the first sub-signal includes at least one channel of audio signal, the second sub-signal includes at least two channels of audio signal; the filter circuit is configured to filter the hybrid audio signal according to a frequency characteristic of the first sub-signal and the second sub-signal to obtain a restored original audio signal; and the speaker, connected with the filter circuit, is configured to output the restored original audio signal.

Abstract: The present application provides an electronic device. After a display screen of the electronic device is attached to a screen frame, the display screen extends beyond the screen frame at at least two opposite edges and extends toward the second side of the display screen by taking the screen frame as an axis, and then the display screen is mounted by a mounting structure connected with the screen frame, so that the display screen is kept flat by a tensile force provided to the display screen via the mounting structure.

Abstract: The disclosure provides a remote control device, a piezoelectric laser pointer, and a remote control system. The remote control device includes a housing, and further includes: a power generator, mounted inside the housing and including a press mechanism and a power generating mechanism, where after being pressed by the press mechanism, the power generating mechanism is deformed under stress and generates electricity; a circuit controller, mounted inside the housing and electrically connected to the power generator; and a signal transceiver, mounted inside the housing, electrically connected to the circuit controller, and configured to transmit and receive signals. In the disclosure, the power generating mechanism generates power after being pressed by the press mechanism, and the power is transferred to the circuit controller, so that the signal transceiver is powered on. Dry batteries are no longer used, thus avoiding environmental pollution caused by used dry batteries.

Abstract: The present application provides an electronic device. After a display screen of the electronic device is attached to a screen frame, the display screen extends beyond the screen frame at at least two opposite edges and extends toward the second side of the display screen by taking the screen frame as an axis, and then the display screen is mounted by a mounting structure connected with the screen frame, so that the display screen is kept flat by a tensile force provided to the display screen via the mounting structure.

Abstract: A display apparatus and a method for processing audio are provided, the display apparatus includes a circuit board provided with a hybrid circuit, a filter circuit and a speaker; the hybrid circuit is configured to receive an original audio signal and superpose a first sub-signal of the original audio signal on a second sub-signal of the original audio signal to obtain a hybrid audio signal; the first sub-signal includes at least one channel of audio signal, the second sub-signal includes at least two channels of audio signal; the filter circuit is configured to filter the hybrid audio signal according to a frequency characteristic of the first sub-signal and the second sub-signal to obtain a restored original audio signal; and the speaker, connected with the filter circuit, is configured to output the restored original audio signal.

Abstract: The invention provides isolated nucleic acid and amino acid sequences of four novel G-protein coupled receptors that are amplified in breast cancer cells, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of G-protein coupled receptors.

Abstract: The invention provides isolated nucleic acid and amino acid sequences of four novel G-protein coupled receptors that are amplified in breast cancer cells, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of G-protein coupled receptors.

Abstract: There are disclosed methods and compositions for the diagnosis, prevention, and treatment of tumors and cancers in mammals, for example, humans, utilizing the CTSZ and CD24 genes, which are amplified colon cancer and/or ovarian cancer and/or breast cancer genes. The CTSZ and CD24 genes, their expressed protein products and antibodies are used diagnostically or as targets for cancer therapy or vaccine; they also are used to identify compounds and reagents useful in cancer diagnosis, prevention, and therapy.

Abstract: The present invention provides methods, reagents, and kits for diagnosing and treating cancer in a mammal, e.g., a human. This invention is based upon the discovery that G2A, GPR4, GPR65, and OGR1 are overexpressed and/or amplified in cancer. Methods to detect cancer or a propensity to develop cancer, to monitor the efficacy of a cancer treatment, and to treat cancer, by inhibiting the expression and/or activity of G2A, GPR4, GPR65, and OGR1 in a cancer cell are included.

Abstract: There are disclosed methods and compositions for the diagnosis, prevention, and treatment of tumors and cancers in mammals, for example, humans, utilizing a gene, which is amplified in many types of cancer. The amplified gene, its expressed protein products and antibodies are used diagnostically or as targets for cancer therapy or as vaccines; they also are used to identify compounds and reagents useful in cancer diagnosis, prevention, and therapy.

Abstract: There are disclosed methods and compositions for the diagnosis, prevention, and treatment of tumors and cancers in mammals, for example, humans, utilizing genes, which are amplified in many types of cancer. The amplified genes, their expressed protein products and antibodies are used diagnostically or as targets for cancer therapy or as vaccines; they also are used to identify compounds and reagents useful in cancer diagnosis, prevention, and therapy.

Abstract: There are disclosed methods and compositions for the diagnosis, prevention, and treatment of tumors and cancers in mammals, for example, humans, utilizing a gene, which is amplified in many types of cancer. The amplified gene, its expressed protein products and antibodies are used diagnostically or as targets for cancer therapy or as vaccines; they also are used to identify compounds and reagents useful in cancer diagnosis, prevention, and therapy.

Abstract: There are disclosed methods and compositions for the diagnosis, prevention, and treatment of tumors and cancers in mammals, for example, humans, utilizing genes, which are amplified in many types of cancer. The amplified genes, their expressed protein products and antibodies are used diagnostically or as targets for cancer therapy or as vaccines; they also are used to identify compounds and reagents useful in cancer diagnosis, prevention, and therapy.

Abstract: The invention provides isolated nucleic acid and amino acid sequences of four novel G-protein coupled receptors that are amplified in breast cancer cells, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of G-protein coupled receptors.

Abstract: There are disclosed methods and compositions for the diagnosis, prevention, and treatment of tumors and cancers in mammals, for example, humans, utilizing the CTSZ and CD24 genes, which are amplified colon cancer and/or ovarian cancer and/or breast cancer genes. The CTSZ and CD24 genes, their expressed protein products and antibodies are used diagnostically or as targets for cancer therapy or vaccine; they also are used to identify compounds and reagents useful in cancer diagnosis, prevention, and therapy.

Abstract: There are disclosed methods and compositions for the diagnosis, prevention, and treatment of tumors and cancers in mammals, for example, humans, utilizing the RecQL5, CTXL, USP13, MCL1, and Pellino1 genes, which are amplified in many types of cancer. The RecQL5, CTXL, USP13, MCL1, and Pellino1 genes, their expressed protein products and antibodies are used diagnostically or as targets for cancer therapy or as vaccines; they also are used to identify compounds and reagents useful in cancer diagnosis, prevention, and therapy.