Patents by Inventor Jianxin Yang

Jianxin Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amplification and overexpression of oncogenes
    Publication number: 20040005615
    Abstract: There are disclosed methods and compositions for the diagnosis, prevention, and treatment of tumors and cancers in mammals, for example, humans, utilizing the RecQL5, CTXL, USP13, MCL1, and Pellino1 genes, which are amplified in many types of cancer. The RecQL5, CTXL, USP13, MCL1, and Pellino1 genes, their expressed protein products and antibodies are used diagnostically or as targets for cancer therapy or as vaccines; they also are used to identify compounds and reagents useful in cancer diagnosis, prevention, and therapy.
    Type: Application
    Filed: May 22, 2003
    Publication date: January 8, 2004
    Inventors: Jing Li, David Mu, Jianxin Yang
  • G-protein coupled receptors amplified in breast cancer
    Patent number: 6638733
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of four novel G-protein coupled receptors that are amplified in breast cancer cells, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of G-protein coupled receptors.
    Type: Grant
    Filed: March 14, 2000
    Date of Patent: October 28, 2003
    Assignee: Tularik Inc.
    Inventors: Scott Powers, Jianxin Yang, Gene Cutler
  • G-protein coupled receptor BCA-GPCR-3
    Patent number: 6635741
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of four novel G-protein coupled receptors that are amplified in breast cancer cells, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of G-protein coupled receptors.
    Type: Grant
    Filed: April 11, 2000
    Date of Patent: October 21, 2003
    Assignee: Tularik Inc.
    Inventors: Scott Powers, Jianxin Yang, Gene Cutler
  • Gene amplification and overexpression in cancer
    Publication number: 20030148341
    Abstract: There are disclosed methods and compositions for the diagnosis, prevention, and treatment of tumors and cancers in mammals, for example, humans, utilizing the MKPX gene, which are amplified colon and/or ovarian and/or prostate cancer genes. The MKPX gene, its expressed protein products and antibodies are used diagnostically or as targets for cancer therapy or vaccine; they are also used to identify compounds and reagents useful in cancer diagnosis, prevention, and therapy.
    Type: Application
    Filed: November 5, 2002
    Publication date: August 7, 2003
    Inventors: Wun Chey Sin, Jianxin Yang
  • Polypeptides and nucleic acids associated with cancer
    Publication number: 20030108931
    Abstract: The present invention provides methods, reagents, and kits for diagnosing and treating cancer in a mammal, e.g., a human. This invention is based upon the discovery that G2A, GPR4, GPR65, and OGR1 are overexpressed and/or amplified in cancer. Methods to detect cancer or a propensity to develop cancer, to monitor the efficacy of a cancer treatment, and to treat cancer, by inhibiting the expression and/or activity of G2A, GPR4, GPR65, and OGR1 in a cancer cell are included.
    Type: Application
    Filed: October 18, 2002
    Publication date: June 12, 2003
    Applicant: Tularik, Inc.
    Inventors: Jianxin Yang, Songzhu An
  • Polypeptides and nucleic acids associated with cancer
    Publication number: 20030059770
    Abstract: The present invention provides methods, reagents, and kits for diagnosing and treating cancer in a mammal, e.g., a human. This invention is based upon the discovery that G2A, GPR4, GPR65, and OGR1 are overexpressed and/or amplified in cancer. Methods to detect cancer or a propensity to develop cancer, to monitor the efficacy of a cancer treatment, and to treat cancer, by inhibiting the expression and/or activity of G2A, GPR4, GPR65, and OGR1 in a cancer cell are included.
    Type: Application
    Filed: May 7, 2001
    Publication date: March 27, 2003
    Inventors: Jianxin Yang, Songzhu An