Abstract: An electrode sheet rewinding apparatus for rewinding an electrode sheet includes a bobbin having a PET film wound therearound, a bobbin holder configured to hold the bobbin, a base plate located under the bobbin holder and configured to support the bobbin holder, a roller type touch roll configured to press an electrode sheet rewound around the bobbin above the bobbin to prevent meandering of the electrode sheet, a vertical plate located at one side of the base plate, the touch roll attached to the vertical plate, and an idle roller unit configured to form a tangential line to the electrode sheet rewound around the bobbin together with the touch roll. The idle roller unit includes an idle roller configured to maintain tension of the electrode sheet and to form a tangential line to the electrode sheet and two driving mechanisms configured to change the position of the idle roller.

Abstract: In one aspect, the disclosure relates to pharmaceutical compositions comprising 2?-deoxycytidine analogs, oral and other dosage formulations containing the same, and methods of making the same. In another aspect, the disclosure relates to methods of treating hematological disorders and diseases associated with abnormal cell proliferation using the same. In a still further aspect, the disclosure relates to kits comprising 2?-deoxycytidine analogs useful for treating hematological disorders and diseases associated with abnormal cell proliferation. In still another aspect, the disclosure relates to methods for increasing fetal hemoglobin levels in a subject. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

Abstract: To provide an epoxy resin composition that exhibits excellent low-dielectric properties and that is excellent in copper foil peel strength and interlayer cohesion strength in a printed-wiring board application, as well as an active ester resin that provides the epoxy resin composition. An active ester resin having a polyaryloxy unit containing a dicyclopentenyl group and represented by the following formula (1), and a polyarylcarbonyl unit. Here, R1 represents a hydrocarbon group having 1 to 8 carbon atoms, R2 represents a hydrogen atom, or formula (1a) or formula (1b), and at least one R2 is formula (1a) or formula (1b); and n represents a number of repetitions of 1 to 5.

Abstract: The present disclosure relates to a method, an apparatus, and a system for detecting and classifying an ischemic stroke based on a medical image. A medical image based ischemic stroke detecting and type classifying apparatus according to an aspect of the present disclosure includes an acquiring unit which collects images related to a brain of at least one patient; a detecting unit which determines whether the at least one patient is a large vessel occlusion patient, based on the collected image; a determining unit which determines whether a type of the large vessel occlusion is embolism or intracranial atherosclerosis (ICAS), when the at least one patient is a large vessel occlusion patient; and a diagnosing unit which provides treatment direction information which is applied differently according to the determined type of the large vessel occlusion.

Abstract: A tape attachment apparatus includes a tape supply unit configured to provide a tape to be attached to a tip of an electrode roll, a tape attachment unit configured to attach the tape provided by the tape supply unit to the electrode roll, and a frame configured to allow the tape attachment unit to be mounted to the frame. A tape attachment process to prevent unwinding of the electrode roll is automatically performed.

Abstract: An automatic electrode supply apparatus configured to automatically supply an electrode in various processes for manufacturing a secondary battery includes a first chuck splicing unit including a splicing portion having a traveling electrode located thereon and a second chuck splicing unit including a splicing portion having a standby electrode located thereon, wherein each of the first and second chuck splicing units includes an edge position control (EPC) sensor configured to measure the position of the edge of a corresponding one of the traveling electrode and the standby electrode in order to prevent distortion or fracture defect of the electrode due to positional deviation between the traveling electrode and the standby electrode, and an automatic electrode supply method using the same.

Abstract: The present disclosure provides crystalline polymorphs of 5-aza-4?-thio-2?-deoxycytidine. The crystalline polymorphs may be formulated in a pharmaceutical composition, optionally in combination with an additional chemotherapeutic agent. The crystalline polymorphs are useful to treat various diseases including blood cancers, such as myelodysplastic syndrome and leukemia. A process for preparing the crystalline polymorphs of 5-aza-4?-thio-2?-deoxycytidine is also disclosed. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: The present disclosure provides the dinucleotide compounds which is useful for treating various cancers. The present disclosure also provides a composition comprising the compound or its pharmaceutically acceptable salt. The present disclosure also provides a medical use of the compound, its salt or the composition comprising the compound or its pharmaceutically acceptable salt for treating cancer. The present disclosure also provides a method of treatment of cancer comprising administering the compound, its salt or the composition comprising the compound or its salt to a subject in need of such treatment.

Abstract: A method of deriving an appropriate condition for cutting a polarizing plate, the method including: (a) preparing a polarizing plate including an adhesive layer and having a cut surface; (b) providing the polarizing plate so that one end of the polarizing plate adjoins a guide unit; (c) moving the polarizing plate on the guide unit; (d) measuring frictional force applied between the polarizing plate and the guide unit while moving the polarizing plate; and (e) deriving the appropriate condition for cutting the polarizing plate based on the measured value of the frictional force and a predetermined adhesive agent leakage determination criterion based on the frictional force.

Abstract: The present disclosure relates to a method, an apparatus, and a system for detecting and classifying an ischemic stroke based on a medical image. A medical image based ischemic stroke detecting and type classifying apparatus according to an aspect of the present disclosure includes an acquiring unit which collects images related to a brain of at least one patient; a detecting unit which determines whether the at least one patient is a large vessel occlusion patient, based on the collected image; a determining unit which determines whether a type of the large vessel occlusion is embolism or intracranial atherosclerosis (ICAS), when the at least one patient is a large vessel occlusion patient; and a diagnosing unit which provides treatment direction information which is applied differently according to the determined type of the large vessel occlusion.

Abstract: A method of optimizing laser welding of two different metals is disclosed herein. In some embodiments, a method for optimizing laser welding of two different metals comprising laser welding a plurality of samples comprising a first metal and a second metal to form a weld between the first metal and the second metal, the weld having a molten area, wherein each sample is laser welded using a different line energy, measuring the content of an intermetallic compound produced by the laser welding in the molten area of the weld in each sample, and determining the line energy of the laser that results in the content of the intermetallic compound produced in the molten area of the weld being less than 10%.

Abstract: The present invention relates to a method of welding an electrode tab which welds an electrode tab and a current collecting layer by using a pulsed laser beam, and a cable type rechargeable battery including an electrode manufactured according to the same.

Abstract: Provided are an epoxy resin composition, which exhibits excellent low dielectric properties, and imparts excellent copper foil peel strength and interlayer cohesive strength when used in printed circuit plate applications; and a phenolic resin or an epoxy resin, which are for forming the epoxy resin composition. The phenolic resin is represented by General Formula (1) below. In the formula, R1's each represent a hydrocarbon group having 1 to 10 carbon atoms; R2's each represent a hydrogen atom, Formula (1a), or Formula (1b), where at least one of R2's is Formula (1a) or Formula (1b); and n represents the number of repetitions of 0 to 5.

Abstract: The present disclosure provides crystalline polymorphs of 5-aza-4?-thio-2?-deoxycytidine. The crystalline polymorphs may be formulated in a pharmaceutical composition, optionally in combination with an additional chemotherapeutic agent. The crystalline polymorphs are useful to treat various diseases including blood cancers, such as myelodysplastic syndrome and leukemia. A process for preparing the crystalline polymorphs of 5-aza-4?-thio-2?-deoxycytidine is also disclosed. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: The present invention relates to pharmaceutical compositions for treating blood cancer, which includes 4?-thio-5-aza-2?-deoxycytidine (Aza-T-dCyd), and methods of treating blood cancer using a composition for oral administration that includes Aza-T-dCyd. The present invention provides a significant blood cancer therapeutic effect without having toxicity in a blood cancer mouse model or a human even with the Aza-T-dCyd dose conventionally known to have toxicity. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: The present invention relates to a method for cutting a separation membrane for a battery, in which the separation membrane is cut by laser radiation on the separation membrane, wherein the pulse repetition rate of the laser is 10 to 500 kHz; a separation membrane manufactured by the method; and a battery comprising the separation membrane. The present invention, in contrast with physical cutting, has the advantage of being capable of cutting a separation membrane for a battery so as to have a uniform cut surface, which was impossible by conventional physical cutting methods.

Abstract: A sheet feeding apparatus includes a sheet stacker to stack at least one sheet; a sheet feed roller disposed at one side of the sheet stacker and to feed a sheet fed from the sheet stacker; a multi-feed prevention roller disposed to face the sheet feed roller and to prevent multi-feed of the sheet fed from the sheet stacker; a magnetic torque limiter disposed coaxially with the multi-feed prevention roller; a hall sensor disposed at one side of the magnetic torque limiter and to detect rotation of the magnetic torque limiter; and a controller configured to rotate the sheet feed roller in a state in which the sheet feed roller and the multi-feed prevention roller are in contact with each other without a sheet and to identify a lifetime of the multi-feed prevention roller by using a signal output from the hall sensor.

Abstract: Provided is a method of providing an unmanned dialogue service according to an embodiment of the inventive concept. The method includes transmitting or receiving text message data constituting a dialogue to or from a user terminal in an unmanned dialogue model, analyzing the dialogue to determine whether a counselor switching situation has occurred, transmitting a dialogue handover request including information regarding the dialogue to a counselor management apparatus when it is determined that the counselor switching situation has occurred, and automatically switching into a mode for relaying transmission or reception of messages between the user terminal and a counselor terminal that receives a task for processing the dialogue handover request allocated by the counselor management apparatus.

Abstract: Provided are a novel [1,2,4]triazolo[4,3-a]quinoxaline derivative, a method for preparing the same, and a pharmaceutical composition for preventing or treating bromodomain extra-terminal (BET) protein-related diseases including cancer and autoimmune diseases, containing the same as an active ingredient.