Abstract: Provided is a method for isolating and proliferating autologous cancer antigen-specific CD8+ T cells, and more particularly, a method for selecting an epitope recognized by CD8+ T cells from autologous cancer antigens present in blood of individual cancer patients; and isolating autologous cancer antigen-specific CD8+ T cells by using a peptide of the selected epitope, and a method of massively proliferating CD8+ T cells by using the method. According to the present invention, it is possible to isolate autologous cancer antigen-specific CD8+ T cells by using the peptide of the CD8 T cell epitope of the autologous cancer antigen present in blood of individual cancer patients instead of a heterologous antigen. Therefore, by using T cells recognizing the autologous cancer antigen, it is possible to effectively select and eliminate cancer cells derived from the cancer patient's own cells. Thus, T cells can be applied to treatment and alleviation of cancer diseases without side effects.

Abstract: Provided are a novel [1,2,4]triazolo[4,3-a]quinoxaline derivative, a method for preparing the same, and a pharmaceutical composition for preventing or treating bromodomain extra-terminal (BET) protein-related diseases including cancer and autoimmune diseases, containing the same as an active ingredient.

Abstract: Disclosed are a method for forming a pattern for liquid crystal orientation of a zenithal bi-stable liquid crystal panel, a liquid crystal orientation substrate including the pattern formed thereby, and a mask substrate used for forming the pattern.

Abstract: A sheet-type medium transporter comprises separation rollers to separate a sheet-type medium from sheet-type media picked up from a load tray in which the sheet-type media are loaded to be transported out of the load tray in a transporting direction; and an air blower coupled to at least one separation roller of the separation rollers to be driven by the at least one separation roller, to supply air in a direction substantially opposite to the transporting direction of the load tray and toward the sheet-type media, to lift the sheet-type medium from the sheet-type media, which is to be separated by the separation rollers.

Abstract: A sheet separation device includes a separating member to contact a feed roller and to separate sheet-type media transported between the feed roller and the separating member, the separating member movable to contact the feed roller at a plurality of contact points on the feed roller along the withdrawing direction to apply different pressing forces corresponding to the plurality of contact points.

Abstract: Disclosed herein is a battery cell configured to have a structure in which an electrode assembly, including positive electrodes and negative electrodes stacked in the state in which separators are disposed respectively between the positive electrodes and the negative electrodes, is mounted in a cell case in the state in which the electrode assembly is impregnated with an electrolyte, wherein the electrode assembly and the cell case are deformable in response to the shape of a device in which the battery cell is mounted, and anti-wrinkle members, for preventing wrinkles from being formed in the cell case when the cell case is deformed, are added to at least portions of the outer surfaces of the electrode assembly.

Abstract: A sheet feeding apparatus includes a sheet stacker to stack at least one sheet; a sheet feed roller disposed at one side of the sheet stacker and to feed a sheet fed from the sheet stacker; a multi-feed prevention roller disposed to face the sheet feed roller and to prevent multi-feed of the sheet fed from the sheet stacker; a magnetic torque limiter disposed coaxially with the multi-feed prevention roller; a hall sensor disposed at one side of the magnetic torque limiter and to detect rotation of the magnetic torque limiter; and a controller configured to rotate the sheet feed roller in a state in which the sheet feed roller and the multi-feed prevention roller are in contact with each other without a sheet and to identify a lifetime of the multi-feed prevention roller by using a signal output from the hall sensor.

Abstract: The present invention relates to a pattern forming method of a liquid crystal device.

Abstract: Disclosed is a secondary battery including a current blocking device. According to the present invention, the secondary battery in which when the secondary battery increases in volume due to overcharging, current flowing to the secondary battery is interrupted by using expansion force due to the increase in volume to improve safety and reliability may be manufactured.

Abstract: The present invention relates to a vesicle containing a saccharide isomerate, a hydrolyzed lupine protein, and an intercorneocyte lipid mimetics as an active ingredient, and a composition for skin external application including the vesicle, and more particularly, to a vesicle including: an aqueous phase part including a saccharide isomerate and a hydrolyzed lupine protein; and an oil phase part including an intercorneocyte lipid mimetics, lysolecithin, and glycerin. The vesicle includes the intercorneocyte lipid mimetics together with the saccharide isomerate and the hydrolyzed lupine protein as contents, so that the vesicle is excellent in a skin barrier recovery function and a skin moisturizing effect upon skin application. In addition, the vesicle is excellent in phase stability, so that the vesicle is suitable to be commercialized as various compositions for skin external application.

Abstract: Disclosed herein is a battery cell having an electrode assembly including one or more unit cells mounted in a variable cell case in a state in which the electrode assembly is impregnated with an electrolyte, wherein at least one of the unit cells includes a flexible electrode that can be bent or curved, an electrode current collector of the flexible electrode includes a first surface, to which an electrode active material is applied, and a second surface, to which no electrode active material is applied, the second surface being opposite to the first surface, and the second surface is provided with a mesh for improving flexibility of the electrode.

Abstract: Provided is a method of providing an unmanned dialogue service according to an embodiment of the inventive concept. The method includes transmitting or receiving text message data constituting a dialogue to or from a user terminal, analyzing the dialogue and determining whether an abnormal situation has occurred, transmitting an assistance request including information regarding the dialogue to a human agent management apparatus when it is determined that the abnormal situation has occurred, receiving dialogue advancement guide information, which is a response to the assistance request, from the human agent management apparatus, wherein the dialogue advancement guide information is configured using input data of a human agent input to a human agent terminal connected to the human agent management apparatus and configured to receive a task for processing the assistance request allocated by the human agent management apparatus, and continuing the dialogue using the dialogue advancement guide information.

Abstract: Provided is a method of providing an unmanned dialogue service according to an embodiment of the inventive concept. The method includes transmitting or receiving text message data constituting a dialogue to or from a user terminal in an unmanned dialogue model, analyzing the dialogue to determine whether a counselor switching situation has occurred, transmitting a dialogue handover request including information regarding the dialogue to a counselor management apparatus when it is determined that the counselor switching situation has occurred, and automatically switching into a mode for relaying transmission or reception of messages between the user terminal and a counselor terminal that receives a task for processing the dialogue handover request allocated by the counselor management apparatus.

Abstract: Provided is a print medium finishing apparatus including a print medium stacking plate; a stacker tray; and a print medium discharging apparatus configured to discharge, to the stacker tray, print media on the print medium stacking plate, wherein the print medium discharging apparatus includes at least one driving gear that is rotatable; a moving member configured to move linearly and curvilinearly with respect to the at least one driving gear and including a motion converting gear configured to engage the at least one driving gear and convert rotation of the at least one driving gear into a linear motion and a curvilinear motion; and a grip member configured to be moved linearly and curvilinearly by the moving member while holding the print media on the print medium stacking plate, and to place the print media on the stacker tray.

Abstract: Disclosed herein is a battery case made of a laminate sheet including an outer coating layer made of a weather-resistant polymer, an inner sealant layer made of a thermally bondable polymer, and a barrier layer interposed between the outer coating layer and the inner sealant layer, wherein an electrode assembly configured to be bent or curved in conformity with the shape of a device, in which a battery cell is mounted, is received in the battery case, and a pattern is formed on at least one surface of the battery case that faces an outer surface of the electrode assembly.

Abstract: A skull implant medication injection port comprises: a mounted portion placed on an upper section of a port insertion hole in a patient's cranium and a medication inlet on a top surface; a medication injection diaphragm that seals the medication inlet of the mounted portion where a needle for injecting a medication is inserted; a medication storage portion coupled with a bottom of the mounted portion stores the medication injected through the medication injection diaphragm; a medication discharge pipe connected to the medication storage portion discharges the medication stored in the medication storage portion; and a rib formed on a perimeter between the mounted portion and the medication storage portion that has a diameter larger than an inner diameter of the port insertion hole. A height of the mounted portion is generally about 4 to 7 mm, and a height of the medication storage portion is generally about 2 to 4.2 mm.

Abstract: A sheet-type medium transporter comprises separation rollers to separate a sheet-type medium from sheet-type media picked up from a load tray in which the sheet-type media are loaded to be transported out of the load tray in a transporting direction; and an air blower coupled to at least one separation roller of the separation rollers to be driven by the at least one separation roller, to supply air in a direction substantially opposite to the transporting direction of the load tray and toward the sheet-type media, to lift the sheet-type medium from the sheet-type media, which is to be separated by the separation rollers.

Abstract: Disclosed herein is a battery cell having an electrode assembly mounted in a variable cell case in a state in which the electrode assembly is impregnated with an electrolyte, the battery cell being configured to be flexibly deformed in response to the shape of a device, in which the battery cell is mounted, wherein an uppermost end electrode and/or a lowermost end electrode of the electrode assembly in the direction in which electrodes are stacked is provided on an electrode current collector thereof, facing the inner surface of the cell case, with an electrode mixture including inert particles, 10 to 100% of the inert particles being distributed on the surface of the electrode mixture such that a concave-convex structure is formed in the surface of the electrode mixture in vertical section.

Abstract: The present disclosure provides a battery cell charging and discharging apparatus configured to charge and discharge a battery cell which is sealed in a state in which an electrode assembly is embedded in a battery case and includes a first die plate having a first charging pin which is connected to a first electrode terminal of the battery cell by being contacted thereto during a charging and discharging process of the battery cell. The first die plate includes an insulation mask of an electrical insulation material formed in a structure covering a remaining part of the battery cell excluding the first electrode terminal at a position corresponding to the first charging pin and mask fixing portions configured to fix both sides of the insulation mask so that a position of the insulation mask is set.

Abstract: Disclosed herein is a battery cell having an electrode assembly mounted in a variable cell case in a state in which the electrode assembly is impregnated with an electrolyte, the battery cell being configured to be flexibly deformed in response to the shape of a device, in which the battery cell is mounted, wherein a coating part including inert particles is formed on at least one outer surface of the electrode assembly.