Abstract: Aspects of the disclosure provide a signal processing circuit that has fast response time to sudden profile changes in an electrical signal. The signal processing circuit includes a processing path configured to process an electrical signal that is generated in response to reading data on a storage medium, and a feed-forward correction module. The feed-forward correction module is configured to detect a profile variation based the electrical signal in a time window, and correct the electrical signal in the time window based on the detected profile variation.

Abstract: A process for forming a mode size converter with an out-of-plane taper formed during deposition with a shadow mask is disclosed. Mode-size converters according to the present invention can have any number of configurations. Measured coupling efficiencies for waveguides with mode size converters according to the present invention show marked improvement.

Abstract: Aspects of the disclosure provide a signal processing circuit to reconstruct data from an analog signal. The signal processing circuit includes an analog to digital converter (ADC), an equalizer, a first timing compensation module, a phase-shift module and a second timing compensation module. The ADC receives an analog input signal, samples the analog input signal based on a sampling clock signal, and converts the sampled analog input signal into a digital output signal. The equalizer equalizes the digital output signal. The first timing compensation module detects a first timing error based on the digital output signal, and adjusts the sampling clock signal based on the first timing error. The phase-shift module phase-shifts the equalized digital output signal based on a phase-shift signal. The second timing compensation module detects a second timing error based on the equalized digital output signal, and adjusts the phase-shift signal based on the second timing error.

Abstract: Devices, systems, methods, and other embodiments associated with wobble channel clocking are described. In one embodiment, an apparatus implemented with a clock generator, a clock scaling logic, radio frequency channel logic, and wobble channel log. The clock generator generates a clocking signal. The clock scaling logic scales the clocking signal to produce a scaled clocking signal. The radio frequency channel logic at least partially decodes a digital radio frequency signal from an optical disk. The wobble channel logic at least partially decodes a digital wobble signal from the optical disk. Either the clocking signal or the scaled clocking signal is used to clock the radio frequency channel logic, and the other clocking signal or the scaled clocking signal is used to clock the wobble channel.

Abstract: A media defect compensation system and method may decouple effects of asymmetry from baseline error compensation computations. In some embodiments, a switching mechanism passes a baseline error signal into a baseline loop when a determination is made that a baseline error signal is not affected by asymmetry, and otherwise freezes the baseline loop when asymmetry may influence baseline error calculations.

Abstract: Described herein are pyrrolo[2,3-d]pyrimidine compounds, their use as Janus Kinase (JAK) inhibitors, pharmaceutical compositions containing these compounds, and methods for their preparation.

Abstract: Compounds of Formula I: wherein X1, X2, L1, A, R, L2, R1, R12, R12a, R13, R14 and R14a are as defined herein, are disclosed.

Abstract: A process for forming a mode size converter with an out-of-plane taper formed during deposition with a shadow mask is disclosed. Mode-size converters according to the present invention can have any number of configurations. Measured coupling efficiencies for waveguides with mode size converters according to the present invention show marked improvement.

Abstract: Compounds are described which inhibit mitogen activated protein kinase-activated protein kinase-2 (MK-2). Methods of using such compounds for the inhibition of MK-2, and for the prevention or treatment of a disease or disorder that is mediated by TNF&agr;, are described, where the method involves administering to the subject an MK-2 inhibiting compound of the present invention. Therapeutic compositions, pharmaceutical compositions and kits which contain the present MK-2 inhibiting compounds are also described.

Abstract: A process for forming a mode size converter with an out-of-plane taper formed during deposition with a shadow mask is disclosed. Mode-size converters according to the present invention can have any number of configurations. Measured coupling efficiencies for waveguides with mode size converters according to the present invention show marked improvement.

Abstract: A wave guide amplifier is presented which has a relatively flat gain over a band of wavelengths. In some embodiments, the amplifier is an erbium doped amplifier and the gain is flat to within 2.5 dB across the C-band. Gain flattening can be accomplished by adjusting the concentration of ground state rare earth ions so that a portion of the signal light is absorbed throughout the amplifier. Signal light at wavelengths corresponding to peaks in the emission spectrum tend to be absorbed more readily than other wavelengths, thereby flattening the gain characteristic of the amplifier.

Abstract: An optical node and method for operation in an ultra long haul backbone network that provides DWDM optical transmission and wavelength networking functionalities are disclosed. The optical node is designed with capabilities for amplification, dispersion compensation, and add/drop functionalities. In one embodiment, three erbium-doped fiber amplifier (EDFA) are cascaded using low nonlinearity and low loss dispersion compensating module (DCM).

Abstract: A reliable and inexpensive method for deploying, operating and maintaining optical amplifiers in a variety of optical networks under a wide range of conditions using channel number reference tables. A preferred embodiment of the current invention may control one or more optical amplifiers or gain blocks operating in a variety of modes such as AGC mode, ALC mode and hybrid AGC/ALC mode without requiring the use of expensive channel counters. Channel number reference tables may be calculated based on initial input optical power output readings and a count of the number of channels initially served by the amplifier. According to the current invention, changes in the number of channels may be monitored and used to control a gain block by monitoring the gain block input optical power output, converting to a gain block voltage and referencing the channel number reference table.

Abstract: This invention relates to a microfabricated capillary electrophoresis chip for detecting multiple redox-active labels simultaneously using a matrix coding scheme and to a method of selectively labeling analytes for simultaneous electrochemical detection of multiple label-analyte conjugates after electrophoretic or chromatographic separation.