Abstract: The present disclosure discloses Microbacterium oleivorans capable of degrading polyethylene terephthalate and an intermediate thereof, and belongs to the technical field of microorganisms. The present disclosure provides Microbacterium oleivorans JWG-G2 capable of degrading the polyethylene terephthalate. After Microbacterium oleivorans JWG-G2 is inoculated into an inorganic salt liquid medium containing 2 g/L polyethylene terephthalate plastic particles with an inoculation quantity of 1×108 CFU/mL to be cultivated for 5 d, the polyethylene terephthalate plastic particles can be partially degraded into monohydroxyethyl terephthalate and terephthalic acid capable of being directly recycled, ester bond functional groups on surfaces of the polyethylene terephthalate plastic particles can be reduced, and a weight loss ratio of the polyethylene terephthalate plastic particles can reach 5.6%.

Abstract: The present invention relates to a multi-target tyrosine kinase inhibitor, which is a compound having protein kinase inhibitory activity as shown in formula (I). The compound is metabolized into an active small molecule td32-4 that inhibits tumor growth in vivo, so as to achieve the anti-tumor effect. Compared with td32-4, the compound of the present invention has significantly improved solubility and oral bioavailability, and shows strong anti-tumor activity in animal in vivo experiments. The present invention relates to a synthetic method for the compound of formula (I) and an application thereof in the field of pharmaceuticals.

Abstract: Provided is a method for improving impurities removal in the protein purification by affinity chromatography, comprising 1) loading a protein sample onto an affinity chromatography column, 2) washing the column with a wash buffer solution comprising Histidine or Imidazole, and a pH-adjusting agent.

Abstract: A method including receiving a command to display a modal dialog. The modal dialog is displayed using both first and second scrolling frames. The first scrolling frame permits scrolling when a modal dialog height exceeds a first scrolling frame constraint. The second scrolling frame permits scrolling of a content section when a content section height exceeds a second scrolling frame constraint. The first scrolling frame constraint has a first and second priorities. The second scrolling frame constraint has a third priority. An orientation of the display screen is determined as being either in a portrait orientation or a landscape orientation. Responsive to determining the physical orientation, an applicable priority that is applicable to the first scrolling frame constraint is assigned. The applicable priority is the first priority in the portrait orientation, and is the second priority in the landscape orientation. After assigning the applicable priority, the modal dialog is displayed.

Abstract: Geographic proximity and network congestion are used to determine efficient routing of data in networks. If two devices are geographically close, then device-to-device communication may be possible. Data may thus be routed using device-to-device communication, which avoids consuming bandwidth in wide area networks and in cellular networks.

Abstract: The disclosure discloses an in-vivo continuous directed evolution system and application thereof, and belongs to the fields of gene engineering and enzyme engineering. The system includes Escherichia coli host bacteria carrying a random mutation module mutagenesis plasmid, a programmed death module toxin-antitoxin system and a target gene expression module target plasmid. The modules are coupled with one another, and target genes are subjected to multiple rounds of continuous mutation by virtue of the random mutation module mutagenesis plasmid in the system, so that the mutation rate of the target genes is further increased, and ultimately, efficient evolution and screening of the target genes in the host bacteria are realized. According to the system, mutations are accurately positioned on the target genes, random mutations in non-target gene regions are reduced, and the system has good practical value and can be applied to directed evolution of various different functional proteins.

Abstract: The present invention discloses a mutant of cyclodextrin glycosyltransferase and belongs to the fields of gene engineering and enzyme engineering. According to the present invention, a mutant having higher disproportionation activity of cyclodextrin glycosyltransferase is obtained by mutating the cyclodextrin glycosyltransferase. The disproportionation activity of enzymes of mutants V6D, S90G, T168A, T171A, T383A, G608A, and V6D/S90G/T168A/T171A/T383A/G608A, is respectively 1.89 times, 1.21 times, 1.21 times, 1.22 times, 1.32 times, 2.03 times, and 3.16 times that of the wild type enzyme in shake flask fermentations.

Abstract: An example method facilitates modification and generation of User Interface (UI) display screens for webpages and web applications, such as process-based software applications. The example method includes receiving a first signal to access a webpage that includes a static UI display screen for a web application; serving the webpage in response to the signal; detecting the dynamic configuration functionality associated with the webpage, wherein the configuration functionality includes code and UI metadata provided in or with a dynamic layout file, the code and UI metadata including one or more rules and specifications for configuring schema used to generate rendering instructions for the dynamic part of the webpage.

Abstract: A transport apparatus may include a patient bed unit for supporting the patient; a transferring unit for moving the patient bed unit along a first direction of the MRI device; and an elevating module for moving the patient bed unit along a second direction of the MRI device.

Abstract: A method includes forming a plurality of low-k dielectric layers over a semiconductor substrate, forming a first plurality of dummy stacked structures extending into at least one of the plurality of low-k dielectric layers, forming a plurality of non-low-k dielectric layers over the plurality of low-k dielectric layers, and forming a second plurality of dummy stacked structures extending into the plurality of non-low-k dielectric layers. The second plurality of dummy stacked structures are over and connected to corresponding ones of the first plurality of dummy stacked structures. The method further includes etching the plurality of non-low-k dielectric layers, the plurality of low-k dielectric layers, and the semiconductor substrate to form a via opening. The via opening is encircled by the first plurality of dummy stacked structures and the second plurality of dummy stacked structures. The via opening is then filled to form a through-via.

Abstract: The present disclosure relates to a display control method, an electronic device, and a storage medium. The method includes: obtaining at least one frame of sensing data representing motion of a target object relative to an electronic device; predicting a to-be-identified region on the electronic device according to the sensing data; and displaying preset information in the to-be-identified region. The preset information is configured to indicate to input biometric information of the target object.

Abstract: An example method facilitates modification and generation of User Interface (UI) display screens for webpages and web applications, such as process-based software applications. The example method includes receiving a first signal to access a webpage that includes a static UI display screen for a web application; serving the webpage in response to the signal; detecting the dynamic configuration functionality associated with the webpage, wherein the configuration functionality includes code and UI metadata provided in or with a dynamic layout file, the code and UI metadata including one or more rules and specifications for configuring schema used to generate rendering instructions for the dynamic part of the webpage.

Abstract: An example system and method facilitates operation of a networked software application that communicates with a network resource during periods of intermittent network connectivity and includes determining when a networked software application is offline and when it is online; selectively intercepting one or more request messages from the networked software application addressed to a network resource when the software application is offline, resulting in a store of intercepted request messages; detecting when the networked software application transitions from being offline to being online; and selectively issuing the one or more request messages to the network resource in a sequence in which the one or more request messages were stored in the store of intercepted request messages.

Abstract: Systems and methods of computer program code or business process design pattern recognition are provided. In embodiments, a method includes identifying, by the computing device, predefined elements and relationships between the elements in a digital industry product based on stored rules; generating, by the computing device, a diagram based on stored image rules, the diagram including graphical notations and text-based information representing the elements and the relationships between the elements; removing, by the computing device, the text-based information from the diagram to produce a modified diagram; and determining, by the computing device, that the modified diagram includes at least one predetermined pattern from a plurality of stored patterns using image object detection.

Abstract: An example system and method facilitates operation of a networked software application during periods of intermittent network connectivity, by selectively intercepting and shredding and/or unshredding service response messages. In a specific embodiment, the example system includes one or more pluggable shredders and unshredders to explode a payload into its constituent structured primitive objects for ease of consumption by the User Interface (UI) of the client application. The exploded payloads are stored in local cache, where the cached data is structured as compared to the received payload. One or more unshredders selectively reconstruct one or more response message payloads if client reissues the corresponding request message while offline. The client may operate as if it is online, and the system will provide one or more mock responses containing the last known data set for the scenario wherein the server cannot be reached.

Abstract: An adaptive screen encoding method comprising: using a computer, creating and storing, in computer memory, a plurality of conditions for use by a server configured to determine which of picture coding type to select; detecting a current picture by a sender for a content type including textual content, graphical content, and natural image content; determining a percentage of static macroblocks corresponding to the current picture; selecting the picture coding type based on the content type, the plurality of conditions, and the percentage of static macroblocks, wherein the method is performed by one or more special-purpose computing devices.

Abstract: Methods, apparatus, and systems for communication over a multi-wire, multi-phase interface are disclosed. A clock recovery method includes generating a combination signal that includes transition pulses, each transition pulse being generated responsive to a transition in a difference signal representative of a difference in signaling state of a pair of wires in a three-wire bus. The combination signal is provided to a logic circuit that is configured to provide a clock signal as its output, where pulses in the combination signal cause the clock signal to be driven to a first state. The logic circuit receives a reset signal that is derived from the clock signal by delaying transitions to the first state while passing transitions from the first state without added delay. The clock signal is driven from the first state after passing a transition of the clock signal to the first state.

Abstract: Disclosed is a mutant of acid phosphatase and an application thereof, belonging to the technical field of biological engineering. The disclosure provides a mutant of acid phosphatase PaAPaseMu3. By expressing the mutant of acid phosphatase PaAPaseMu3 in Escherichia coli and using a whole-cell conversion method, L-ascorbic acid is transformed into L-ascorbate-2-phosphate. Moreover, a catalytic system of the mutant of acid phosphatase PaAPaseMu3 is optimized from the aspects of reaction pH and temperature, so that a yield of L-ascorbate-2-phosphate can reach 90.1 g/L and a molar yield can reach 75.1%. Therefore, the problems of a high substrate cost, environmental pollution and the like before are greatly reduced, laying a foundation for the industrial green production of L-ascorbate-2-phosphate.

Abstract: A method of preparation and application for a glass ceramic sealing thin strip with high sealing performance, differing from using conventional glass ceramic packaging paste applied to the junction of the cell stack assembly and connecting plates. The glass ceramic sealing thin strip of present invention utilizes tape casting to produce a single layer or multi-layer stacking in accordance with the required thickness of the glass-ceramic sealing thin strip, and cutting the glass ceramic sealing thin strips from molds in accordance with the geometry of cell stacks with equal thickness of the glass ceramic sealing thin strip for SOFC cell stack assembly, aiming to overcome the setbacks of the conventional dispensing method with glass ceramic packaging paste that makes the thickness difficult to control, and to effectively improve sealing performance of the cell stack assembly and the power generation efficiency, and achieve commercial application with mass production.