Patents by Inventor Johannes Ludescher

Johannes Ludescher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibacterial substituted 7-acylamino-3-(methylhydrazono) methyl-cephalosporins and intermediates
    Publication number: 20040132709
    Abstract: A compound of formula 1
    Type: Application
    Filed: November 12, 2003
    Publication date: July 8, 2004
    Inventors: Gerd Ascher, Josef Wieser, Michael Schranz, Johannes Ludescher, Johannes Hildebrandt
  • Macrolide solvates
    Publication number: 20040053862
    Abstract: Azithromycin in the form of a monohydrate comprising from 4.0% to 6.5% of water, a process for its preparation and its use in pharmaceutical compositions.
    Type: Application
    Filed: October 10, 2003
    Publication date: March 18, 2004
    Inventors: Victor Centellas, Jose Diago, Rafael Garcia, Johannes Ludescher
  • Macrolides
    Patent number: 6703372
    Abstract: Azithromycin in the form of a stable monohydrate and processes for the preparation of azithromycin in the form of an, e.g. stable, monohydrate.
    Type: Grant
    Filed: December 18, 2001
    Date of Patent: March 9, 2004
    Assignee: Biochemie S.A.
    Inventors: Victor Centellas, Rafael Garcia, Marta Poch, José Diago, Johannes Ludescher, Immaculada Bosch
  • Antibacterial substituted 7-acylamino-3-(methylhydrazono) methyl-cephalosporins and intermediates
    Patent number: 6693095
    Abstract: A compound of formula wherein W, V, R1, R5, R2, R3 and R4 have various meanings, a process for their production and their use as a pharmaceutical.
    Type: Grant
    Filed: November 13, 2001
    Date of Patent: February 17, 2004
    Assignee: Biochemie Gesellschaft m.b.H.
    Inventors: Gerd Ascher, Josef Wieser, Michael Schranz, Johannes Ludescher, Johannes Hildebrandt
  • Process for purification of a cephalosporin derivative
    Publication number: 20030208065
    Abstract: A process for the purification of cefixime via a novel tert.octylamine salt of a cefixime intermediate which may be crystalline and which may be produced in a one pot reaction from 7-amino-3-vinyl-ceph-3-em-4-carboxylic acid.
    Type: Application
    Filed: September 30, 2002
    Publication date: November 6, 2003
    Inventors: Martin Decristoforo, Johannes Ludescher, Hubert Sturm, Werner Veit
  • Antibacterial cephalosporins
    Publication number: 20030191105
    Abstract: A compound of formula 1
    Type: Application
    Filed: December 3, 2002
    Publication date: October 9, 2003
    Inventors: Gerd Ascher, Johannes Ludescher
  • Cephalosporin intermediates
    Publication number: 20030153748
    Abstract: A process and intermediates in the production of cefotiam (hexetil).
    Type: Application
    Filed: February 12, 2003
    Publication date: August 14, 2003
    Inventors: Peter Kremminger, Johannes Ludescher, Siegfried Wolf
  • Purification process
    Publication number: 20030153747
    Abstract: Processes for the depletion of 7-ADCA in mixtures of vinyl-ACA with 7-ADCA via novel salts of vinyl-ACA or via chromatography.
    Type: Application
    Filed: January 21, 2003
    Publication date: August 14, 2003
    Inventors: Johannes Ludescher, Werner Veit
  • Antibacterial substituted 7-acylamino-3-(methylhydrazono) methyl-cephalosporins and intermediates
    Publication number: 20030114665
    Abstract: A compound of formula 1
    Type: Application
    Filed: September 23, 2002
    Publication date: June 19, 2003
    Inventors: Gerd Ascher, Josef Wieser, Michael Schranz, Johannes Ludescher, Johannes Hildebrandt
  • &bgr;-lactam production
    Patent number: 6552186
    Abstract: The present invention provides processes for the production of a compound of formula I wherein X, R1 and R2 are substituents conventional in cephalosporin chemistry; especially a compound of formula I is ceftrixone, cefotaxime; e.g., in the form of a salt.
    Type: Grant
    Filed: October 11, 2001
    Date of Patent: April 22, 2003
    Assignee: Biochemie Gesellschaft m.b.H.
    Inventors: Benjamin Gerlach, Johannes Ludescher, Klaus Totschnig
  • Antibacterial cephalosporins
    Patent number: 6531465
    Abstract: A compound of formula wherein Ac, R1 and R2 have various meanings, a process for a preparation thereof and its use as a pharmaceutical, i.e. as antibacterial agent.
    Type: Grant
    Filed: May 21, 2001
    Date of Patent: March 11, 2003
    Assignee: Biochemie Gesellschaft m.b.H.
    Inventors: Gerd Ascher, Johannes Ludescher
  • Process for production of ceftiofur
    Patent number: 6504026
    Abstract: Process for preparing ceftiofur having formula I: in the form of the sodium salt.
    Type: Grant
    Filed: November 20, 2001
    Date of Patent: January 7, 2003
    Assignee: Biochemie Gesellschaft m.b.H.
    Inventors: Andreas Berger, Martin Decristoforo, Johannes Ludescher, Herbert Schleich
  • Process for the preparation of cefpodoxime proxetil diastereoisomers
    Patent number: 6489470
    Abstract: A process for increasing the diastereoisomeric ratio (B/A+B), wherein B is the more apolar and A is the more polar of two diastereoisomers, of a mixture of diastereoisomers of a compound of formula the diastereoisomers being with respect to the carbon atom marked with a star in formula I, comprising treating a mixture of diastereoisomers of a compound of formula I with alcohol and water and isolating the precipitated compound of formula I in an increased diastereoisomeric ratio (B/A+B) of 0.5 to 0.6.
    Type: Grant
    Filed: August 21, 2000
    Date of Patent: December 3, 2002
    Assignee: Biochemie Gesellschaft m.b.H.
    Inventors: Julia Greil, Johannes Ludescher, Klaus Totschnig, Siegfried Wolf
  • Beta-lactam production
    Publication number: 20020156272
    Abstract: 1
    Type: Application
    Filed: April 10, 2002
    Publication date: October 24, 2002
    Inventors: Benjamin Gerlach, Johannes Ludescher, Klaus Totschnig
  • Beta-lactam production
    Publication number: 20020128469
    Abstract: 1
    Type: Application
    Filed: October 11, 2001
    Publication date: September 12, 2002
    Inventors: Benjamin Gerlach, Johannes Ludescher, Klaus Totschnig
  • Cephalosporines having cyclic aminoguanidine substituents as antibiotics
    Patent number: 6440957
    Abstract: A compound useful as an anti-bacterial agent, having the formula wherein R2 together with the nitrogen atom to which it is attached forms a cyclic aminoguanidine group or derivative thereof as defined
    Type: Grant
    Filed: September 21, 2000
    Date of Patent: August 27, 2002
    Assignee: Biochemie Gesellschaft m.b.H.
    Inventors: Gerd Ascher, Werner Heilmayer, Johannes Ludescher, Johannes Hildebrandt, Michael Schranz, Josef Wieser
  • Antibacterial substituted 7-acylamino-3-(methylhydrazono) methyl-cephalosporins and intermediates
    Publication number: 20020115852
    Abstract: A compound of formula 1
    Type: Application
    Filed: November 13, 2001
    Publication date: August 22, 2002
    Inventors: Gerd Ascher, Josef Wieser, Michael Schranz, Johannes Ludescher, Johannes Hildebrandt
  • Antibacterial substituted 7-acylamino-3-(methylhydrazono) methyl-cephalosporins and intermediates
    Publication number: 20020091252
    Abstract: A compound of formula 1
    Type: Application
    Filed: November 13, 2001
    Publication date: July 11, 2002
    Inventors: Gerd Ascher, Josef Wieser, Michael Schranz, Johannes Ludescher, Johannes Hildebrandt
  • Process for the production of 3-vinyl cephalosporins
    Patent number: 6414140
    Abstract: A process for the production of a 3-vinylcephalosporin compound of formula I wherein R1 and R2 denote hydrogen or an organic group by a Wittig reaction reacting first a compound of formula II with a compound of formula P(R4)3 or P(OR4)3 to produce a compound of formula III and secondly reacting the compound of formula III with a weak base of formula or of formula R10—COO−W+ wherein R5 is hydrogen, alkly or aryl and R6 and R7 are each an activated group of formula —COOR8, —CN, —SO2R8, —COR8 or —CON(R8)2; or R5 and R8 are each aryl and R7 is an activated group of formula —COOR8, —CN, —SO2R8, —COR8 or —CON(R8)2, W+ is an alkali metal cation and R10 is alkyl or aryl to produce a compound of formula IV and finally reacting a compound of formula IV with a compound of formula V to produce a compound of formula I.
    Type: Grant
    Filed: February 23, 2001
    Date of Patent: July 2, 2002
    Assignee: Biochemie Gesellschaft m.b.H.
    Inventors: Josef Wieser, Gerd Ascher, Johannes Ludescher, Herbert Sturm
  • Organic Compounds
    Publication number: 20020082248
    Abstract: Process for preparing ceftiofur having formula 1: 1
    Type: Application
    Filed: November 20, 2001
    Publication date: June 27, 2002
    Inventors: Andreas Berger, Martin Decristoforo, Johannes Ludescher, Herbert Schleich