Abstract: Systems and methods for facilitating reservations of shared desks, phone booths, and other spaces or areas within a workspace for members of the workspace are described. For example, a space reservation system receives a request to reserve a space for a member and selects a space suitable for the member based on one or more work environment characteristics associated with the space. The system also presents various interfaces for displaying available spaces and facilitating interactions between the member and the space.

Abstract: A medical tracking system includes a percutaneous needle, a localization element and a navigation system is disclosed. The percutaneous needle has an elongate shaft extending between a proximal end portion, which is attached to a handle, and distal end portion that terminates at a distal tip. An inner surface of the elongate shaft defines a working channel that extends from a port at the proximal end portion to the distal tip. The localization element is incorporated into the elongate shaft distal from the handle and proximate the distal end portion. The navigation system is configured for tracking the localization element and to provide a real-time display of a position and orientation of the distal tip relative to an anatomy of a patient.

Abstract: A marking assembly includes a hollow cannula having a wall extending from a proximal end to a distal end. The wall defines a lumen of the cannula. The wall includes at least one opening at a distal portion of the cannula. A stylet is configured to be received in the lumen of the cannula. The stylet has a wall extending from a proximal end to a distal end. When the stylet is received in the lumen of the cannula, a circumferential space is defined between the wall of the stylet and the wall of the cannula such that fluid entering the circumferential space will exit the cannula through the at least one opening of the cannula.

Abstract: Embodiments described herein include systems and methods for providing a management interface for controlling multiple households. The management interface may be provided as an application on a mobile device or as an Internet webpage. An example implementation involves a device displaying representations of: a plurality of households; an indication of a selected household; one or more zones within the selected household; and a representation of media being played by a selected zone of the one or more zones. While displaying the representations, the device receives, from a server, data indicating updated information associated with the plurality of households; and, in response, updates the graphical display to display at least an updated representation of media being played by the selected zone.

Abstract: Authenticating a mobile user device with a mobile network operator in advance of an MNO authentication request from the mobile user device can be done by a satellite network sending an authentication request to the MNO system, obtaining a set of authentication vectors related to the mobile user device, storing them into a proxy home location register, receiving the MNO authentication request from the mobile user device, generating an authentication request response based on the authentication vectors, sending the authentication request response to the mobile user device, receiving an authentication response including a received signed response, comparing the received signed response with the stored signed response, and if the received signed response and stored signed response match, deem that to be a successful authentication, add an MNO location update message to a request queue and forward the MNO location update message to the MNO system over the channel when available.

Abstract: A rotating electric machine with a rotor shaft having a target magnet. High current conductors conductively couples inverter circuitry with the stator windings. Control circuitry and a magnetic position sensor facing the target magnet are disposed on a printed circuit board, the printed circuit board being axially positioned between the target magnet and a heat sink. The high current conductors extend axially from proximate the heat sink to the stator assembly and are positioned radially outwardly of the magnetic position sensor. A ferrous shield member has a major surface defining a plane perpendicular to the rotational axis. The magnetic position sensor is axially disposed between the shield member and the target magnet and the shield member is positioned between the printed circuit board and the heat sink. The shield member has a surface area covering most of the area radially inward of the high current conductors.

Abstract: A microelectronic package may be fabricated having at least one microelectronic die attached to a microelectronic substrate, wherein the microelectronic substrate includes at least one notch formed in at least one side thereof. The microelectronic dice may be attached to a first surface of the microelectronic substrate and in electronic communication with a bond pad on a second surface of the microelectronic substrate with a bond wire which extends through the notch in the microelectronic substrate.

Abstract: Embodiments of the present invention provide a novel and non-obvious method, system and computer program product for pre-routing network security for cloud computing. In an embodiment of the invention, a pre-routing network security method for cloud computing includes receiving in a routing component, such as a load balancer, of a cloud computing environment that includes at least two different virtualized containers, a stream of packets targeting a destination network address and, before processing the stream of packets in the routing component, diverting the stream of packets to a packet inspector executing in one of the virtualized containers. Then, only a fraction of the packets of the diverted stream of packets are received in the routing component from the packet inspector, and, the fraction of the packets are then processed in the router such that the fraction of the packets are routed to the destination network address.

Abstract: The present invention relates to a combination treatment which comprises (a) at least one ERK inhibitor preferably Compound B as described herein, and (b) a c-RAF inhibitor or a pharmaceutically acceptable salt thereof, preferably Compound A, which may be combined into a single pharmaceutical composition or prepared for separate or sequential administration. It includes a c-RAF inhibitor and an ERK inhibitor prepared for simultaneous, separate or sequential administration for the treatment of a proliferative disease, particularly an advanced solid tumor that harbors a Mitogen-activated protein kinase (MAPK) alteration, and includes methods of using these compounds in combination as well as a commercial package comprising such combination.

Abstract: Embodiments described herein include systems and methods for providing a management interface for controlling multiple households. The management interface may be provided as an application on a mobile device or as an Internet webpage. An example implementation involves a device displaying representations of: a plurality of households; an indication of a selected household; one or more zones within the selected household; and a representation of media being played by a selected zone of the one or more zones. While displaying the representations, the device receives, from a server, data indicating updated information associated with the plurality of households; and, in response, updates the graphical display to display at least an updated representation of media being played by the selected zone.

Abstract: A microelectronic package may be fabricated having at least one microelectronic die attached to a microelectronic substrate, wherein the microelectronic substrate includes at least one notch formed in at least one side thereof. The microelectronic dice may be attached to a first surface of the microelectronic substrate and in electronic communication with a bond pad on a second surface of the microelectronic substrate with a bond wire which extends through the notch in the microelectronic substrate.

Abstract: A nerve monitoring system facilitates monitoring an integrity of a nerve.

Abstract: Embodiments described herein include systems and methods for providing a management interface for controlling multiple households. The management interface may be provided as an application on a mobile device or as an Internet webpage. An example implementation involves a device displaying representations of: a plurality of households; an indication of a selected household; one or more zones within the selected household; and a representation of media being played by a selected zone of the one or more zones. While displaying the representations, the device receives, from a server, data indicating updated information associated with the plurality of households; and, in response, updates the graphical display to display at least an updated representation of media being played by the selected zone.

Abstract: The present invention relates to a pharmaceutical combination comprising dabrafenib, trametinib and an Erk-inhibitor; pharmaceutical compositions comprising the same; and methods of using such combinations and compositions in the treatment or prevention of conditions in which MAPK pathway inhibition is beneficial, for example, in the treatment of cancers.

Abstract: The present invention relates to a combination treatment which comprises (a) at least one ERK inhibitor preferably Compound B as described herein, and (b) a c-RAF inhibitor or a pharmaceutically acceptable salt thereof, preferably Compound A, which may be combined into a single pharmaceutical composition or prepared for separate or sequential administration. It includes a c-RAF inhibitor and an ERK inhibitor prepared for simultaneous, separate or sequential administration for the treatment of a proliferative disease, particularly an advanced solid tumor that harbors a Mitogen-activated protein kinase (MAPK) alteration, and includes methods of using these compounds in combination as well as a commercial package comprising such combination.

Abstract: An antenna with adjustable tilt angle includes: a mounting structure; an antenna mount fixed to the mounting structure; an antenna mounted to the antenna mount, the antenna configured to produce an antenna beam; a remote electrical tilt (RET) unit operatively associated with the antenna to adjust a pointing tilt angle of the antenna beam; a tilt pointing direction sensor mounted to the antenna, the pointing direction tilt sensor configured to detect the a pointing angle of the antenna relative to a baseline standard; and a controller operatively connected with the RET unit and the pointing direction tilt sensor, the controller configured to receive signals from the pointing direction tilt sensor and transmit signals to the RET unit to adjust the tilt pointing angle of the antenna beam based on the detected angle of the antenna.

Abstract: The present disclosure relates to anti-CD32b antibody molecules which selectively bind human CD32b. Also provided herein are compositions comprising anti-CD32b antibody molecules in combination with other compounds, and methods of using the combinations to treat subject with cancer.

Abstract: Embodiments of the present invention provide a novel and non-obvious method, system and computer program product for pre-routing network security for cloud computing. In an embodiment of the invention, a pre-routing network security method for cloud computing includes receiving in a routing component, such as a load balancer, of a cloud computing environment that includes at least two different virtualized containers, a stream of packets targeting a destination network address and, before processing the stream of packets in the routing component, diverting the stream of packets to a packet inspector executing in one of the virtualized containers. Then, only a fraction of the packets of the diverted stream of packets are received in the routing component from the packet inspector, and, the fraction of the packets are then processed in the router such that the fraction of the packets are routed to the destination network address.

Abstract: The present invention relates to anti-cKIT antibodies, antibody fragments, antibody drug conjugates, and their uses for the treatment of cancer.

Abstract: Embodiments described herein include systems and methods for providing a management interface for controlling multiple households. The management interface may be provided as an application on a mobile device or as an Internet webpage. An example implementation involves a device displaying representations of: a plurality of households; an indication of a selected household; one or more zones within the selected household; and a representation of media being played by a selected zone of the one or more zones. While displaying the representations, the device receives, from a server, data indicating updated information associated with the plurality of households; and, in response, updates the graphical display to display at least an updated representation of media being played by the selected zone.