Patents by Inventor John C. Burnett, Jr.

John C. Burnett, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chimeric aquaretic and natriuretic polypeptides lacking vasodilatory activity
    Patent number: 9102757
    Abstract: This document provides aquaretic and natriuretic polypeptides. For example, this document provides polypeptides having aquaretic and/or natriuretic activities. In some cases, a polypeptide provided herein can have aquaretic and natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing aquaretic and/or natriuretic activities within a mammal.
    Type: Grant
    Filed: July 16, 2013
    Date of Patent: August 11, 2015
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Horng H. Chen, John C. Burnett, Jr.
  • Natriuretic polypeptides for reducing restenosis
    Patent number: 9079973
    Abstract: Materials and methods related to using natriuretic polypeptides to reduce proliferation of smooth muscle cells, and to reduce or prevent restenosis.
    Type: Grant
    Filed: May 7, 2013
    Date of Patent: July 14, 2015
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: John C. Burnett, Jr., Horng H. Chen, Ondrej Lisy
  • TREATING CARDIOVASCULAR OR RENAL DISEASES
    Publication number: 20150005371
    Abstract: This document provides methods and materials for treating cardiovascular and/or renal diseases. For example, AAV9 vectors designed to express natriuretic polypeptides, nucleic acid molecules encoding natriuretic polypeptides, methods for making AAV9 vectors, and methods for using such vectors or molecules to treat cardiovascular and/or renal diseases are provided.
    Type: Application
    Filed: January 4, 2013
    Publication date: January 1, 2015
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Yasuhiro Ikeda, Stephen James Russell, Alessandro Cataliotti, John C. Burnett, JR., Jason M. Tonne
  • NATRIURETIC POLYPEPTIDE DELIVERY SYSTEMS
    Publication number: 20140357561
    Abstract: This document provides natriuretic polypeptide delivery systems. For example, methods and materials related to natriuretic polypeptide delivery systems, methods and materials related to the use of such delivery systems to deliver natriuretic polypeptides to a mammal over a pro-longed period of time (e.g., weeks to months), and methods and materials related to treating heart failure conditions are provided.
    Type: Application
    Filed: July 24, 2014
    Publication date: December 4, 2014
    Inventors: Horng H. Chen, John C. Burnett, JR., Lim Soo Ghim, Subramanian K. Venkatraman
  • PROANP COMPOSITIONS AND METHODS FOR TREATING ACUTE HEART FAILURE
    Publication number: 20140274901
    Abstract: Materials and Methods related to using proANP to treat cardiorenal disease, including acute heart failure.
    Type: Application
    Filed: March 12, 2014
    Publication date: September 18, 2014
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: Tomoko Ichiki, John C. Burnett, JR.
  • Natriuretic polypeptide delivery systems
    Patent number: 8835601
    Abstract: This document provides natriuretic polypeptide delivery systems. For example, methods and materials related to natriuretic polypeptide delivery systems, methods and materials related to the use of such delivery systems to deliver natriuretic polypeptides to a mammal over a pro-longed period of time (e.g., weeks to months), and methods and materials related to treating heart failure conditions are provided.
    Type: Grant
    Filed: March 7, 2013
    Date of Patent: September 16, 2014
    Assignees: Mayo Foundation for Medical Education and Research, Nanyang Technological University
    Inventors: Horng H. Chen, John C. Burnett, Jr., Lim Soo Ghim, Subramanian S. Venkatraman
  • NATRIURETIC POLYPEPTIDES WITH UNIQUE PHARMACOLOGIC PROFILES
    Publication number: 20140228294
    Abstract: This document provides natriuretic polypeptides. For example, this document provides polypeptides having a natriuretic activity. In some cases, a polypeptide provided herein can have natriuretic activities without inducing excessive hypotension. This document also provides methods and materials for inducing natriuretic activities within a mammal.
    Type: Application
    Filed: April 21, 2014
    Publication date: August 14, 2014
    Applicant: Mayo Foundation for Medical Education and Research
    Inventors: John C. Burnett, JR., Candace Y.W. Lee
  • NATRIURETIC POLYPEPTIDE DELIVERY SYSTEMS
    Publication number: 20140179605
    Abstract: This document provides natriuretic polypeptide delivery systems. For example, methods and materials related to natriuretic polypeptide delivery systems, methods and materials related to the use of such delivery systems to deliver natriuretic polypeptides to a mammal over a pro-longed period of time (e.g., weeks to months), and methods and materials related to treating heart failure conditions are provided.
    Type: Application
    Filed: March 7, 2013
    Publication date: June 26, 2014
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Horng H. Chen, John C. Burnett, JR.
  • Chimeric natriuretic polypeptides with unique pharmacologic profiles
    Patent number: 8741842
    Abstract: This document provides natriuretic polypeptides. For example, this document provides polypeptides having a natriuretic activity. In some cases, a polypeptide provided herein can have natriuretic activities without inducing excessive hypotension. This document also provides methods and materials for inducing natriuretic activities within a mammal.
    Type: Grant
    Filed: June 16, 2009
    Date of Patent: June 3, 2014
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: John C. Burnett, Jr., Candace Y. W. Lee
  • SUBCUTANEOUS DELIVERY OF A LONG-ACTING NATRIURETIC PEPTIDE
    Publication number: 20140066367
    Abstract: This document provides methods and material related to natriuretic polypeptides. For example, substantially pure polypeptides having a natriuretic peptide activity, nucleic acids encoding polypeptides having a natriuretic peptide activity, host cells containing such nucleic acids, and methods for inducing a natriuretic or diuretic activity within a mammal are provided.
    Type: Application
    Filed: March 12, 2013
    Publication date: March 6, 2014
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Horng H. Chen, John C. Burnett, JR., Daniel J. McCormick
  • Chimeric natriuretic peptides without hypotensive inducing capability
    Patent number: 8642550
    Abstract: This document provides natriuretic polypeptides. For example, this document provides polypeptides having a natriuretic activity. In some cases, a polypeptide provided herein can have natriuretic activities without lowering blood pressure. Methods and materials for inducing natriuretic activities within a mammal also are provided.
    Type: Grant
    Filed: October 21, 2009
    Date of Patent: February 4, 2014
    Assignees: Mayo Foundation for Medical Education and Research, Regents of the University of Minnesota
    Inventors: Deborah Dickey, John C. Burnett, Jr., Lincoln R. Potter
  • NATRIURETIC POLYPEPTIDES
    Publication number: 20140005358
    Abstract: This document provides methods and materials related to natriuretic polypeptides and the use of natriuretic polypeptides to treat cardiovascular and/or renal conditions. For example, chimeric polypeptides having at least one amino acid segment (e.g., N-terminus tail, ring structure, C-terminus tail, or a combination thereof) of a natriuretic peptide (e.g., ANP, BNP, CNP, URO, or DNP) and an amino acid segment of an angiotensin polypeptide (e.g., Ang-(1-7)) are provided.
    Type: Application
    Filed: August 21, 2012
    Publication date: January 2, 2014
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Candace Y.W. Lee, John C. Burnett, Jr.
  • LONG ACTING ATRIAL NATRIURETIC PEPTIDE (LA-ANP) AND METHODS FOR USE THEREOF
    Publication number: 20130303454
    Abstract: Materials and Methods related to making and using natriuretic polypeptides having a mutation that results in an extended carboxy terminus.
    Type: Application
    Filed: May 8, 2013
    Publication date: November 14, 2013
    Applicants: University of Iowa Research Foundation, Mayo Foundation for Medical Education and Research
    Inventors: John C. Burnett, JR., Timothy M. Olson, Leonid V. Zingman, Denice Marie Hodgson-Zingman
  • AQUARETIC AND NATRIURETIC POLYPEPTIDES LACKING VASODILATORY ACTIVITY
    Publication number: 20130296241
    Abstract: This document provides aquaretic and natriuretic polypeptides. For example, this document provides polypeptides having aquaretic and/or natriuretic activities. In some cases, a polypeptide provided herein can have aquaretic and natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing aquaretic and/or natriuretic activities within a mammal.
    Type: Application
    Filed: July 16, 2013
    Publication date: November 7, 2013
    Inventors: Horng H. Chen, John C. Burnett, Jr.
  • NATRIURETIC POLYPEPTIDES FOR REDUCING OR PREVENTING RESTENOSIS
    Publication number: 20130281375
    Abstract: Materials and methods related to using natriuretic polypeptides to reduce proliferation of smooth muscle cells, and to reduce or prevent restenosis.
    Type: Application
    Filed: May 7, 2013
    Publication date: October 24, 2013
    Inventors: John C. Burnett, JR., Horng H. Chen, Ondrej Lisy
  • Chimeric aquaretic and natriuretic polypeptides lacking vasodilatory activity
    Patent number: 8530422
    Abstract: This document provides aquaretic and natriuretic polypeptides. For example, this document provides polypeptides having aquaretic and/or natriuretic activities. In some cases, a polypeptide provided herein can have aquaretic and natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing aquaretic and/or natriuretic activities within a mammal.
    Type: Grant
    Filed: August 23, 2012
    Date of Patent: September 10, 2013
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Horng H. Chen, John C. Burnett, Jr.
  • Natriuretic polypeptides for reducing or preventing restenosis
    Patent number: 8455438
    Abstract: Materials and methods related to using natriuretic polypeptides to reduce proliferation of smooth muscle cells, and to reduce or prevent restenosis.
    Type: Grant
    Filed: December 29, 2009
    Date of Patent: June 4, 2013
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: John C. Burnett, Jr., Horng H. Chen, Ondrej Lisy
  • AQUARETIC AND NATRIURETIC POLYPEPTIDES LACKING VASODILATORY ACTIVITY
    Publication number: 20130023478
    Abstract: This document provides aquaretic and natriuretic polypeptides. For example, this document provides polypeptides having aquaretic and/or natriuretic activities. In some cases, a polypeptide provided herein can have aquaretic and natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing aquaretic and/or natriuretic activities within a mammal.
    Type: Application
    Filed: August 23, 2012
    Publication date: January 24, 2013
    Inventors: Horng H. Chen, John C. Burnett, JR.
  • Natriuretic peptide receptor-C agonists
    Patent number: 8357656
    Abstract: This document relates to methods and materials involved in preferentially activating natriuretic peptide receptor-C polypeptides. For example, agonists of natriuretic peptide receptor-C polypeptides as well as methods for activating natriuretic peptide receptor-C polypeptides are provided herein.
    Type: Grant
    Filed: September 15, 2008
    Date of Patent: January 22, 2013
    Assignees: Mayo Foundation for Medical Education and Research, Regents of the University of Minnesota
    Inventors: Robert D. Simari, Shuchong Pan, John C. Burnett, Jr., Horng H. Chen, Lincoln R. Potter
  • Diuretic and natriuretic polypeptides lacking the blood pressure lowering property
    Patent number: 8324162
    Abstract: This document provides diuretic and natriuretic polypeptides. For example, this document provides polypeptides having diuretic and/or natriuretic activities. In some cases, a polypeptide provided herein can have diuretic and natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing diuretic and/or natriuretic activities within a mammal.
    Type: Grant
    Filed: August 8, 2007
    Date of Patent: December 4, 2012
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Robert D. Simari, Shuchong Pan, John C. Burnett, Jr., Horng H. Chen