Patents by Inventor John C. Burnett, Jr.

John C. Burnett, Jr. has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aquaretic and natriuretic polypeptides lacking vasodilatory activity
    Patent number: 8283318
    Abstract: This document provides aquaretic and natriuretic polypeptides. For example, this document provides polypeptides having aquaretic and/or natriuretic activities. In some cases, a polypeptide provided herein can have aquaretic and natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing aquaretic and/or natriuretic activities within a mammal.
    Type: Grant
    Filed: September 7, 2007
    Date of Patent: October 9, 2012
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Horng H. Chen, John C. Burnett, Jr.
  • LONG ACTING ATRIAL NATRIURETIC PEPTIDE (LA-ANP) AND METHODS FOR USE THEREOF
    Publication number: 20120108514
    Abstract: Materials and Methods related to making and using natriuretic polypeptides having a mutation that results in an extended carboxy terminus.
    Type: Application
    Filed: July 8, 2010
    Publication date: May 3, 2012
    Applicants: UNIVERSITY OF IOWA RESEARCH FOUNDATION, MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: John C. Burnett, JR., Timothy M. Olson, Leonid V. Zingman, Denice Marie Hodgson-Zingman
  • NATRIURETIC POLYPEPTIDES HAVING MUTATIONS WITHIN THEIR DISULFIDE RINGS
    Publication number: 20120053123
    Abstract: Materials and Methods related to making and using natriuretic polypeptides having a mutation in the ring portion of their structure.
    Type: Application
    Filed: May 5, 2010
    Publication date: March 1, 2012
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: John C. Burnett, JR., Horng H. Chen
  • NATRIURETIC ACTIVITIES
    Publication number: 20120010142
    Abstract: This document provides methods and material related to natriuretic polypeptides. For example, substantially pure polypeptides having a natriuretic peptide activity, nucleic acids encoding polypeptides having a natriuretic peptide activity, host cells containing such nucleic acids, and methods for inducing a natriuretic or diuretic activity within a mammal are provided.
    Type: Application
    Filed: September 21, 2011
    Publication date: January 12, 2012
    Inventors: John C. Burnett, JR., Timothy M. Olson
  • Polynucleotides encoding for fusion proteins with natriuresis activity
    Patent number: 8063191
    Abstract: This document provides methods and material related to natriuretic polypeptides. For example, substantially pure polypeptides having a natriuretic peptide activity, nucleic acids encoding polypeptides having a natriuretic peptide activity, host cells containing such nucleic acids, and methods for inducing a natriuretic or diuretic activity within a mammal are provided.
    Type: Grant
    Filed: August 11, 2010
    Date of Patent: November 22, 2011
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: John C Burnett, Jr., Timothy M Olson
  • NATRIURETIC POLYPEPTIDES FOR REDUCING OR PREVENTING RESTENOSIS
    Publication number: 20110269684
    Abstract: Materials and Methods related to using natriuretic polypeptides to reduce proliferation of smooth muscle cells, and to reduce or prevent restenosis.
    Type: Application
    Filed: December 29, 2009
    Publication date: November 3, 2011
    Inventors: John C. Burnett, JR., Horng H. Chen, Ondrej Lisy
  • CHIMERIC NATRIURETIC POLYPEPTIDES AND METHODS FOR INHIBITING CARDIAC REMODELING
    Publication number: 20110152194
    Abstract: Materials and methods related to chimeric polypeptides containing the amino acid sequence of CNP and the C-terminal sequence of DNP. The polypeptides are natriuretic and diuretic, GFR enhancing, cardiac unloading, renin inhibiting and less hypotensive when compared to BNP. The polypeptides also inhibit cardiac fibroblast proliferation.
    Type: Application
    Filed: June 3, 2009
    Publication date: June 23, 2011
    Inventors: John C. Burnett, JR., Horng H. Chen, Ondrej Lisy
  • NATRIURETIC POLYPEPTIDES WITH UNIQUE PHARMACOLOGIC PROFILES
    Publication number: 20110152191
    Abstract: This document provides natriuretic polypeptides. For example, this document provides polypeptides having a natriuretic activity. In some cases, a polypeptide provided herein can have natriuretic activities without inducing excessive hypotension. This document also provides methods and materials for inducing natriuretic activities within a mammal.
    Type: Application
    Filed: June 16, 2009
    Publication date: June 23, 2011
    Applicant: National Institutes of Health (NIH)
    Inventors: John C. Burnett, Jr., Candace Y.W. Lee
  • Chimeric natriuretic peptides
    Patent number: 7964564
    Abstract: Peptides of Dendroaspis, including chimeric peptides thereof, are provided, as well as methods of using the peptides as natriuretics, diuretics, and/or vasodilators.
    Type: Grant
    Filed: May 15, 2008
    Date of Patent: June 21, 2011
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: John C. Burnett, Jr., Ondrej Lisy
  • NATRIURETIC PEPTIDE RECEPTOR-C AGONISTS
    Publication number: 20100311660
    Abstract: This document relates to methods and materials involved in preferentially activating natriuretic peptide receptor-C polypeptides. For example, agonists of natriuretic peptide receptor-C polypeptides as well as methods for activating natriuretic peptide receptor-C polypeptides are provided herein.
    Type: Application
    Filed: September 15, 2008
    Publication date: December 9, 2010
    Inventors: Robert D. Simari, Shuchong Pan, John C. Burnett, JR., Horng H. Chen, Lincoln R. Potter
  • NATRIURETIC ACTIVITIES
    Publication number: 20100305051
    Abstract: This document provides methods and material related to natriuretic polypeptides. For example, substantially pure polypeptides having a natriuretic peptide activity, nucleic acids encoding polypeptides having a natriuretic peptide activity, host cells containing such nucleic acids, and methods for inducing a natriuretic or diuretic activity within a mammal are provided.
    Type: Application
    Filed: August 11, 2010
    Publication date: December 2, 2010
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: John C. Burnett, JR., Timothy M. Olson
  • Polypeptides with natriuresis activity
    Patent number: 7803901
    Abstract: This document provides methods and material related to natriuretic polypeptides. For example, substantially pure polypeptides having a natriuretic peptide activity, nucleic acids encoding polypeptides having a natriuretic peptide activity, host cells containing such nucleic acids, and methods for inducing a natriuretic or diuretic activity within a mammal are provided.
    Type: Grant
    Filed: September 15, 2006
    Date of Patent: September 28, 2010
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: John C. Burnett, Jr., Timothy M. Olson
  • Natriuretic polypeptides
    Patent number: 7754852
    Abstract: This document provides natriuretic polypeptides. For example, this document provides polypeptides having a natriuretic activity. In some cases, a polypeptide provided herein can have natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing natriuretic activities within a mammal.
    Type: Grant
    Filed: July 18, 2008
    Date of Patent: July 13, 2010
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: John C. Burnett, Jr., Candace Y. W. Lee
  • CHIMERIC NATRIURETIC PEPTIDES
    Publication number: 20090170756
    Abstract: Peptides of Dendroaspis, including chimeric peptides thereof, are provided, as well as methods of using the peptides as natriuretics, diuretics, and/or vasodilators.
    Type: Application
    Filed: May 15, 2008
    Publication date: July 2, 2009
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: John C. Burnett, JR., Ondrej Lisy
  • NATRIURETIC ACTIVITIES
    Publication number: 20090069243
    Abstract: This document provides methods and material related to natriuretic polypeptides. For example, substantially pure polypeptides having a natriuretic peptide activity, nucleic acids encoding polypeptides having a natriuretic peptide activity, host cells containing such nucleic acids, and methods for inducing a natriuretic or diuretic activity within a mammal are provided.
    Type: Application
    Filed: September 15, 2006
    Publication date: March 12, 2009
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: John C. Burnett, JR., Timothy M. Olson
  • NATRIURETIC POLYPEPTIDES
    Publication number: 20090054337
    Abstract: This document provides natriuretic polypeptides. For example, this document provides polypeptides having a natriuretic activity. In some cases, a polypeptide provided herein can have natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing natriuretic activities within a mammal.
    Type: Application
    Filed: July 18, 2008
    Publication date: February 26, 2009
    Inventors: John C. Burnett, JR., Candace Y.W. Lee
  • Chimeric natriuretic peptides
    Patent number: 7384917
    Abstract: Peptides of Dendroaspis, including chimeric peptides thereof, are provided, as well as methods of using the peptides as natriuretics, diuretics, and/or vasodilators.
    Type: Grant
    Filed: September 23, 2004
    Date of Patent: June 10, 2008
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: John C. Burnett, Jr., Ondrej Lisy
  • Chimeric natriuretic peptides
    Patent number: 6818619
    Abstract: Peptides of Dendroaspis, including chimeric peptides thereof, are provided, as well as methods of using the peptides as natriuretics, diuretics, and/or vasodilators.
    Type: Grant
    Filed: March 26, 2002
    Date of Patent: November 16, 2004
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: John C. Burnett, Jr., Ondrej Lisy
  • CHIMERIC NATRIURETIC PEPTIDES
    Publication number: 20020082219
    Abstract: Peptides of Dendroaspis, including chimeric peptides thereof, are provided, as well as methods of using the peptides as natriuretics, diuretics, and/or vasodilators.
    Type: Application
    Filed: December 17, 1999
    Publication date: June 27, 2002
    Inventors: JOHN C. BURNETT, JR., ONDREJ LISY
  • Chimeric natriuretic peptides
    Patent number: 6407211
    Abstract: Peptides of Dendroaspis, including chimeric peptides thereof, are provided, as well as methods of using the peptides as natriuretics, diuretics, and/or vasodilators.
    Type: Grant
    Filed: December 17, 1999
    Date of Patent: June 18, 2002
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: John C. Burnett, Jr., Ondrej Lisy