Abstract: A scrubbing tool for cleaning a surface that has a handle for holding by a user in a cleaning operation. The handle has a first connector. The scrubbing tool also has a cleaning head having a second connector configured to mate with the first connector in order to attach the cleaning head to the handle in an engaged position. The cleaning head is comprised entirely of a material configured to dissolve in water and has a cleaning agent.

Abstract: Described herein are methods and computer systems for classification of CD8 T-cell topology using a patient response-based linear cutoff model. A plurality of histology images of tissue samples in a plurality of patients are received by a computer system. An image analysis of the plurality of histology images is performed to obtain a CD8+ T-cell abundance in the tumor parenchyma and stroma in each of the plurality of histology images. Real inflammation scores and tumor infiltration scores are determined based on a polar coordinate transformation of the CD8+ T-cell abundance in the tumor parenchyma and stroma. Based on the real inflammation scores and tumor infiltration scores, a feature space is generated, and linear boundaries or linear cutoffs between a plurality of classifications in the feature space are identified based on the real inflammation scores, the tumor infiltration scores, and patient response data.

Abstract: A scrubbing tool for cleaning a surface that has a handle for holding by a user in a cleaning operation. The handle has a first connector. The scrubbing tool also has a cleaning head having a second connector configured to mate with the first connector in order to attach the cleaning head to the handle in an engaged position. The cleaning head is comprised entirely of a material configured to dissolve in water and has a cleaning agent.

Abstract: Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

Abstract: The present disclosure relates generally to modulators of human glycolate oxidase enzyme and methods of use and manufacture thereof.

Abstract: In some embodiments, nested filters can be implemented as a radio-frequency device that includes a substrate, and first and second filter devices mounted on the substrate with respective support structures, such that at least a portion of the second filter device is positioned in a space defined by an underside of the first filter device and the support structures for the first filter device. Such a radio-frequency device can be, for example, a packaged module for use in an electronic device such as a wireless device.

Abstract: The present disclosure relates generally to certain 6-azabenzimidazole compounds, pharmaceutical compositions comprising said compounds, and methods of making and using said compounds and pharmaceutical compositions. The compounds and compositions disclosed herein may be used for the treatment or prevention of diseases, disorders, or infections modifiable by hematopoietic progenitor kinase 1 (HPK1) inhibitors, such as HBV, HIV, cancer, and/or a hyper-proliferative disease.

Abstract: A method of routing call signalling to a destination address from a first cellular mobile communications network comprising a plurality of cells to one of a plurality of smaller cells collectively identified in said first mobile communications network by a single virtual cell identifier.

Abstract: An anti-piracy system for a vessel produces a non-lethal all of water along the side of the vessel to wash away a pirate. A cylindrical cap has a top, a bottom edge, a hollow interior, and an outside surface. A slit is defined within the outside surface forming a partial opening within the cap from the interior to the outside surface. A threaded hose fitting is formed within the interior, wherein the cap can be secured to a fire suppression node on the vessel with the downward face positioned over a side of the vessel for forcibly dispersing water through the slit downward over the side of the vessel. The cap is positioned near the deck of the vessel, just over the side of the vessel such that upon activation of the tire suppression system the water is directed downward over the side of the vessel.

Abstract: A telecommunications network termination device has the capability to connect to a network access point using a primary fixed line address by a first route and also, using a second network address, by a backup routing to a shared wireless access point. Connection status messages are transmitted over the primary routing. If these are not detected by the network, it causes traffic to the user device to be diverted over the backup routing to the second network address. It also transmits instructions to the user device to route outgoing traffic by the same secondary route. The secondary route is identified from network topology data stored by the network control server.

Abstract: A mobile communications handset (12) is capable of connection through two different networks (2, 27). When it is out of contact with its preferred local wireless access system (27), the handset will seek a hand-over to the cellular network (2), and will become registered as a “roaming” handset currently connected to the cellular network (2). The cellular network (2) reports this location information to the call server (28), as it would to the HLR of any normal visiting handset, so that incoming calls to the PSTN (6) destined for the user (12) can be routed by way of the cellular network. Outgoing calls are handled as conventional cellular telephony calls. When contact with a local wireless access system (27) is re-established, the contact information is passed to the call server 28, which reports to the cellular network (2) that a handover has occurred.

Abstract: A method of routing call signalling to a destination address from a first cellular mobile communications network comprising a plurality of cells to one of a plurality of smaller cells collectively identified in said first mobile communications network by a single virtual cell identifier.

Abstract: An anti-piracy system for a vessel produces a non-lethal all of water along the side of the vessel to wash away a pirate. A cylindrical cap has a top, a bottom edge, a hollow interior, and an outside surface. A slit is defined within the outside surface forming a partial opening within the cap from the interior to the outside surface. A threaded hose fitting is formed within the interior, wherein the cap can be secured to a fire suppression node on the vessel with the downward face positioned over a side of the vessel for forcibly dispersing water through the slit downward over the side of the vessel. The cap is positioned near the deck of the vessel, just over the side of the vessel such that upon activation of the tire suppression system the water is directed downward over the side of the vessel.

Abstract: An repeater device (11) connects to a master femtocell (cellular access point) (10) device, which in turn connects directly to the Internet (3) by means of a broadband access circuit (2), and through the Internet to the fixed infrastructure of a cellular network. The inbuilt radio configuration services of the repeater femtocell (11) and master femtocell (10) allow it to configure its co-existence with the main femtocell unit, to ensure the optimum coverage is provided for the user, without interference between the two units.

Abstract: A wireless terminal (1) capable of handling voice and data traffic is configured to use an internet connection (3) when available and a connection to a cellular network (7) otherwise. To allow handover between the systems, voice calls using the VoIP protocol are tunnelled to a bridging point (74) between the internet (3) and cellular network (7). However, to avoid the need for data to be routed by way of the cellular network and then back into the internet, the tunnelled connection between the hub and the mobile access bridge (74) is replaced with two separate tunnels (14, 47) respectively connecting the user (1) and MAB (74) with an intermediate breakout point, such as is a VoIP network controller (4). From this breakout point a third connection (46) is made to the internet, for carrying non-voice data traffic by way of a network access control proxy (5).

Abstract: Cordless access over an extended area is provided by a network of co-operating wireless access points (10, 20, 30) etc all operating on a common channel, such that continuous communication with a mobile handset (9) is possible within the combined coverage of the set of access points. The access points are all recognised by the handset (9) as being part of the same connection. The access points are in communication with each other, either by wireless connections (11, 51) or by wired connections (21, 41), so that they can communicate between each other, a home base site controller 60, and a connection (31) to the public network. Under the control of the HBSC (60), all the access points (10, 20), broadcast a common service set identifier SSID and operate on the channel selected by the HBSC (60), and consequently a communications session can continue seamlessly, regardless of which access point is currently in use.

Abstract: If an attempt by a first user to contact another party fails, a callback server sets a flag. The callback server monitors terminals that have such flags set and is arranged to transmit an alert to the calling party when the called party next becomes available. However, if at the time when the called party becomes available, the calling party is himself no longer available, being now switched off or busy, an additional flag in the store, indicative of activity by the calling party, prevents a callback alert from being generated until the monitoring process can obtain availability indications in respect of both parties simultaneously. Availability may be determined by factors such as available bandwidth or terminal capabilities. A callback may be initiated when a predetermined number of called parties become available to participate in a conference call.

Abstract: For each of a number of users (11, 12, 13), a network-based server (14) maintains a respective data set (141, 142, 143) of each data file currently stored on the user device, such as scheduling details, electronic mail, documents, etc. Each data set comprises a master copy (161) indicative of the latest data intended for that user (11). When a user (either the user associated with the user device, or some other user (151, 152, 153) authorised to do so) makes a change to the user data, for example rescheduling a meeting, the master copy (161) is updated. The server (14) also identifies how this data differs from that held on a second copy (171), which duplicates what is currently stored on the terminal, and generates a third dataset (181) identifying the changes that would need to be made to change the duplicate copy (171) to correspond to the master copy (161). This change data is forwarded to the user terminal when it next makes contact with the network.

Abstract: The present invention provides methods of treating bone cancer, inducing differentiation of bone tumor cells, inhibiting bone tumor growth, inducing bone tumor regression or treating a hyperproliferative cell disorder by administering a pharmaceutically effective amount of a bone morphogenic protein or a nucleic acid encoding the bone morphogenic protein.