Patents by Inventor John J. Leonard

John J. Leonard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9665791
    Abstract: In one embodiment, a method of identifying the dominant orientations of a scene comprises representing a scene as a plurality of directional vectors. The scene may comprise a three-dimensional representation of a scene, and the plurality of directional vectors may comprise a plurality of surface normals. The method further comprises determining, based on the plurality of directional vectors, a plurality of orientations describing the scene. The determined plurality of orientations explains the directionality of the plurality of directional vectors. In certain embodiments, the plurality of orientations may have independent axes of rotation. The plurality of orientations may be determined by representing the plurality of directional vectors as lying on a mathematical representation of a sphere, and inferring the parameters of a statistical model to adapt the plurality of orientations to explain the positioning of the plurality of directional vectors lying on the mathematical representation of the sphere.
    Type: Grant
    Filed: April 3, 2015
    Date of Patent: May 30, 2017
    Assignee: Massachusetts Institute of Technology
    Inventors: Julian Straub, Guy Rosman, Oren Freifeld, John J. Leonard, John W. Fisher, III
  • Publication number: 20170143721
    Abstract: Compositions may include a pharmaceutical active agent, a high viscosity liquid carrier material (HVLCM), a lactic acid-based polymer, and an organic solvent. Related compositions and methods are also disclosed.
    Type: Application
    Filed: January 5, 2017
    Publication date: May 25, 2017
    Applicants: DURECT CORPORATION, ZOGENIX INC.
    Inventors: Jeremy C. WRIGHT, Wilma TAMRAZ, John J. LEONARD, John W. GIBSON, Keith E. BRANHAM, Stefania SJOBECK, Brooks BOYD, Christopher M. RUBINO
  • Patent number: 9572812
    Abstract: Compositions may include a pharmaceutical active agent, a high viscosity liquid carrier material (HVLCM), a lactic acid-based polymer, and an organic solvent. Related compositions and methods are also disclosed.
    Type: Grant
    Filed: January 14, 2016
    Date of Patent: February 21, 2017
    Assignee: DURECT CORPORATION
    Inventors: Jeremy C. Wright, Wilma Tamraz, John J. Leonard, John W. Gibson, Keith E. Branham, Stefania Sjobeck, Brooks Boyd, Christopher M. Rubino
  • Publication number: 20160206618
    Abstract: Compositions may include a pharmaceutical active agent, a high viscosity liquid carrier material (HVLCM), a lactic acid-based polymer, and an organic solvent. Related compositions and methods are also disclosed.
    Type: Application
    Filed: January 14, 2016
    Publication date: July 21, 2016
    Applicants: DURECT CORPORATION, ZOGENIX INC.
    Inventors: Jeremy C. WRIGHT, Wilma TAMRAZ, John J. LEONARD, John W. GIBSON, Keith E. BRANHAM, Stefania SJOBECK, Brooks BOYD, Christopher M. RUBINO
  • Publication number: 20160038596
    Abstract: Compositions may include a pharmaceutical active agent, a high viscosity liquid carrier material (HVLCM), a lactic acid-based polymer, and an organic solvent. Related compositions and methods are also disclosed. For instance, a carrier formulation for controlled release of injectable drugs is disclosed. The formulation may include a non-water soluble high viscosity liquid which may be sucrose acetate isobutyrate, a lactic-acid based polymer which may be a poly(lactic acid)(glycolic acid), and an organic solvent which maintains the composition in a monophasic form at 25° C. in one atmosphere. Drug in the formulation may be released upon administration such that less than 10% (e.g. 2-8%) of drug is released in the first 5 hours; 10% to 80% of the drug is released during a period of 5 hours to 7 days after administration; and 10% to 40% of the drug is released gradually over a period of 7 days to 28 days from initial administration. The drug may be an anti-schizophrenia agent delivered by injection.
    Type: Application
    Filed: March 11, 2014
    Publication date: February 11, 2016
    Applicants: DURECT CORPORATION, ZOGENIX, INC.
    Inventors: Jeremy C. WRIGHT, Wilma TAMRAZ, John J. LEONARD, John W. GIBSON, Keith E. BRANHAM, Stefania SJOBECK, Brooks Boyd, Christopher M. RUBINO
  • Publication number: 20150286893
    Abstract: In one embodiment, a method of identifying the dominant orientations of a scene comprises representing a scene as a plurality of directional vectors. The scene may comprise a three-dimensional representation of a scene, and the plurality of directional vectors may comprise a plurality of surface normals. The method further comprises determining, based on the plurality of directional vectors, a plurality of orientations describing the scene. The determined plurality of orientations explains the directionality of the plurality of directional vectors. In certain embodiments, the plurality of orientations may have independent axes of rotation. The plurality of orientations may be determined by representing the plurality of directional vectors as lying on a mathematical representation of a sphere, and inferring the parameters of a statistical model to adapt the plurality of orientations to explain the positioning of the plurality of directional vectors lying on the mathematical representation of the sphere.
    Type: Application
    Filed: April 3, 2015
    Publication date: October 8, 2015
    Inventors: Julian Straub, Guy Rosman, Oren Freifeld, John J. Leonard, John W. Fisher, III
  • Publication number: 20140308352
    Abstract: Compositions may include a pharmaceutical active agent, a high viscosity liquid carrier material (HVLCM), a lactic acid-based polymer, and an organic solvent. Related compositions and methods are also disclosed.
    Type: Application
    Filed: March 11, 2014
    Publication date: October 16, 2014
    Applicants: ZOGENIX INC., DURECT CORPORATION
    Inventors: Jeremy C. WRIGHT, Wilma TAMRAZ, John J. LEONARD, John W. GIBSON, Keith E. BRANHAM, Stefania SJOBECK, Brooks BOYD, Christopher M. RUBINO
  • Patent number: 6807846
    Abstract: The present invention provides an apparatus and method for evaluating the integrity of a seal on liquid-filled container. According to one aspect of the invention, the apparatus comprises a tank for containing a liquid solution and a clamp with a first and second member between which the container is engaged. The clamp is positioned with respect to the tank such that a portion of the container properly situated in the clamp will extend into the tank and contact the liquid solution. A ram and cylinder are operatively connected to the clamp to engage the container. A seat is provided to support a portion of the container such that at least a portion of the container supported by the seat will extend into the tank. A drill is provided to pierce a surface of the container to make an opening. The drill is positioned such that the opening can be made while the container is in the clamp and/or the seat such that at least a portion of the container extends into the tank.
    Type: Grant
    Filed: January 14, 2002
    Date of Patent: October 26, 2004
    Assignee: The Quaker Oats Company
    Inventors: John J. Leonard, Steven Robert Ehardt, Newell Esmond, Kurt Aaron Kreutzmann, Timothy J. Hamilton, John Konieczka
  • Publication number: 20040198202
    Abstract: The present invention relates to cordless wax applicator/buffer that comprises an electric orbital wax applicator/buffer, which has a rotatable, eccentrically moving head for buffing external surfaces and a casing housing an electric motor for turning the rotatable head. The cordless wax applicator/buffer also comprises a battery compartment on the top of the casing for housing for a rechargeable battery source of power. A rim means extends outwardly from the casing for gripping the cordless wax applicator/buffer to operate it and comprises a rounded finger engaging outer edge and a recessed palm receiving inner portion. The cordless wax applicator/buffer further comprises a plug receptacle for receiving a plug means connectable to an electric power source for recharging the rechargeable battery.
    Type: Application
    Filed: April 3, 2003
    Publication date: October 7, 2004
    Inventor: John J. Leonard
  • Publication number: 20020174711
    Abstract: The present invention provides an apparatus and method for evaluating the integrity of a seal on liquid-filled container. According to one aspect of the invention, the apparatus comprises a tank for containing a liquid solution and a clamp with a first and second member between which the container is engaged. The clamp is positioned with respect to the tank such that a portion of the container properly situated in the clamp will extend into the tank and contact the liquid solution. A ram and cylinder are operatively connected to the clamp to engage the container. A seat is provided to support a portion of the container such that at least a portion of the container supported by the seat will extend into the tank. A drill is provided to pierce a surface of the container to make an opening. The drill is positioned such that the opening can be made while the container is in the clamp and/or the seat such that at least a portion of the container extends into the tank.
    Type: Application
    Filed: January 14, 2002
    Publication date: November 28, 2002
    Inventors: John J. Leonard, Steven Robert Ehardt, Newell Esmond, Kurt Aaron Kreutzmann, Timothy J. Hamilton, John Konieczka
  • Patent number: 6415651
    Abstract: The present invention provides an apparatus and method for evaluating the integrity of a seal on liquid-filled container. According to one aspect of the invention, the apparatus comprises a tank for containing a liquid solution and a clamp with a first and second member between which the container is engaged. The clamp is positioned with respect to the tank such that a portion of the container properly situated in the clamp will extend into the tank and contact the liquid solution. A ram and cylinder are operatively connected to the clamp to engage the container. A seat is provided to support a portion of the container such that at least a portion of the container supported by the seat will extend into the tank. A drill is provided to pierce a surface of the container to make an opening. The drill is positioned such that the opening can be made while the container is in the clamp and/or the seat such that at least a portion of the container extends into the tank.
    Type: Grant
    Filed: June 23, 2000
    Date of Patent: July 9, 2002
    Assignee: The Quaker Oats Company
    Inventors: John J. Leonard, Steven Robert Ehardt, Newell Esmond, Kurt Aaron Kreutzmann, Timothy J. Hamilton, John Konieczka
  • Publication number: 20020053234
    Abstract: The present invention provides an apparatus and method for evaluating the integrity of a seal on liquid-filled container. According to one aspect of the invention, the apparatus comprises a tank for containing a liquid solution and a clamp with a first and second member between which the container is engaged. The clamp is positioned with respect to the tank such that a portion of the container properly situated in the clamp will extend into the tank and contact the liquid solution. A ram and cylinder are operatively connected to the clamp to engage the container. A seat is provided to support a portion of the container such that at least a portion of the container supported by the seat will extend into the tank. A drill is provided to pierce a surface of the container to make an opening. The drill is positioned such that the opening can be made while the container is in the clamp and/or the seat such that at least a portion of the container extends into the tank.
    Type: Application
    Filed: June 23, 2000
    Publication date: May 9, 2002
    Applicant: THE QUAKER OATS COMPANY
    Inventors: John J. Leonard , Steven Robert Ehardt , Newell Esmond , Kurt Aaron Kreutzmann , Timothy J. Hamilton , John Konieczka
  • Patent number: 6068850
    Abstract: This invention relates to stable liquid aqueous formulations of peptide compounds at high concentrations. These stable formulations comprise at least about 10% peptide in water. They may be stored at elevated temperatures for long periods of time and are especially useful in implantable delivery devices for long term delivery of drug.
    Type: Grant
    Filed: February 11, 1999
    Date of Patent: May 30, 2000
    Assignee: Alza Corporation
    Inventors: Cynthia L. Stevenson, Sally A. Tao, Steven J. Prestrelski, James B. Eckenhoff, deceased, Jeremy C. Wright, John J. Leonard, Jr.
  • Patent number: 6066619
    Abstract: This invention relates to stable non-aqueous protic formulations of peptide compounds. These stable formulations comprise peptide in non-aqueous protic solvent. They may be stored at elevated temperatures for long periods of time and are especially useful in implantable delivery devices for long term delivery of drug.
    Type: Grant
    Filed: April 16, 1999
    Date of Patent: May 23, 2000
    Assignee: Alza Corporation
    Inventors: Cynthia L. Stevenson, Sally A. Tao, Steven J. Prestrelski, James B. Eckenhoff, Jeremy C. Wright, John J. Leonard, Jr.
  • Patent number: 5981489
    Abstract: This invention relates to stable non-aqueous protic formulations of peptide compounds. These stable formulations comprise peptide in non-aqueous protic solvent. They may be stored at elevated temperatures for long periods of time and are especially useful in implantable delivery devices for long term delivery of drug.
    Type: Grant
    Filed: June 13, 1997
    Date of Patent: November 9, 1999
    Assignee: Alza Corporation
    Inventors: Cynthia L. Stevenson, Sally A. Tao, Steven J. Prestrelski, James B. Eckenhoff, deceased, Jeremy C. Wright, John J. Leonard, Jr.
  • Patent number: 5916582
    Abstract: This invention relates to stable liquid aqueous formulations of peptide compounds at high concentrations. These stable formulations comprise at least about 10% peptide in water. They may be stored at elevated temperatures for long periods of time and are especially useful in implantable delivery devices for long term delivery of drug.
    Type: Grant
    Filed: June 13, 1997
    Date of Patent: June 29, 1999
    Assignee: ALZA Corporation
    Inventors: Cynthia L. Stevenson, Sally A. Tao, Steven J. Prestrelski, James B. Eckenhoff, deceased, Jeremy C. Wright, John J. Leonard, Jr.
  • Patent number: 5424458
    Abstract: The present invention provides a novel integration of an existing MTBE process unit with new propylene oxide producing facilities whereby through this integration new propylene oxide production is achieved without significant increase in MTBE production.
    Type: Grant
    Filed: March 8, 1994
    Date of Patent: June 13, 1995
    Assignee: Arco Chemical Technology, L.P.
    Inventors: Gordon A. Sullivan, Herry E. Eilerts-de Haan, William J. Piel, John J. Leonard
  • Patent number: 5363305
    Abstract: A navigation system for a mobile autonomous robot that includes apparatus for creating and maintaining a map of an environment the mobile autonomous robot is to traverse including provision for storing in a map at an assigned location features representative of geometric beacons located in the environment. Because of the uncertainty in its sensor's operating conditions and changes in the environment, a credibility measure is associated with each map feature stored. This credibility measure is increased or decreased whenever the map feature assigned to a location matches or does not match, respectively, a geometric beacon corresponding to such location. Whenever a geometric beacon is observed for a location that does into match a previously stored map features, an appropriate map feature is added for such location.
    Type: Grant
    Filed: February 28, 1992
    Date of Patent: November 8, 1994
    Assignee: NEC Research Institute, Inc.
    Inventors: Ingemar Cox, John J. Leonard, Hugh Durrant-Whyte
  • Patent number: 4737595
    Abstract: A method for dehydrogenating dehydrogenatable hydrocarbons which comprises contacting said hydrocarbons with a solid comprising at least one reducible oxide of at least one metal which oxides when contacted with hydrocarbons at the temperature are reduced and produce dehydrogenated hydrocarbon products and water, the solid being associated with a silica support. The oxide is reduced by the contact which is carried at about 500.degree. to 100.degree. C. The reducible metal oxides are regenerated by oxidizing the reduced composition with oxygen.
    Type: Grant
    Filed: April 16, 1984
    Date of Patent: April 12, 1988
    Assignee: Atlantic Richfield Company
    Inventors: C. Andrew Jones, John J. Leonard, John A. Sofranko
  • Patent number: 4670619
    Abstract: An improved method for converting methane to higher hydrocarbon products by contacting a hydrocarbon gas comprising methane, an oxygen-containing gas and a reducible metal oxide under conditions effective to produce higher hydrocarbon products and water, the improvement which comprises conducting the contacting in the presence of at least one stabilizer selected from the group consisting of chalcogens and compounds thereof.
    Type: Grant
    Filed: May 24, 1985
    Date of Patent: June 2, 1987
    Assignee: Atlantic Richfield Company
    Inventors: Howard P. Withers, Jr., C. Andrew Jones, John J. Leonard, John A. Sofranko, Anne M. Gaffney