Abstract: A screw-driven extrusion system includes a novel screw-drive extruder. The extruder includes a motor-driven screw. The screw moves solid pellets from a feed hopper into a section that is actively heated. The solid pellets fully liquefy as they pass through the heated section. A control system controls screw, heating, and optionally cooling, operations to selectively control flow of liquefied material from the extruder's tip. The dynamically-controlled can continuously adjust its feed speed and temperature to keep up with continuously changing demands of a larger control system involved in monitoring and running a corresponding 3-D printer in an additive manufacturing process. In contrast to wirefeed extrusion systems that rely on the rigidity of the material in “wire”-formed feedstock, this screw-driven extrusion system is well-suited to use of less-rigid thermoplastic elastomers for the manufacture of objects for use in soft robotics, medical and mold-making applications.

Abstract: Approaches for secondary-game-mode sessions based on primary-game-mode arrangements of user-controlled elements are provided. Actions by user-controlled elements of a first user or other game-space elements in a primary game mode of a game space may be managed. A session request for a session in a secondary game mode of the game space may be received from the first user. A first session for the first user may be executed in the secondary game mode such that: (i) the first session involves artificial-intelligence-controlled elements as opponents against the user-controlled elements; (ii) an arrangement of the user-controlled elements at a beginning of the first session is the same as an arrangement of the user-controlled elements in the primary game mode at a time of the session request; and (iii) impacts on the user-controlled elements during the first session in the secondary game mode are not reflected in the primary game mode.

Abstract: Systems and methods for processing sequencing data of ribonucleic acid (RNA) molecules from a test sample include obtaining a plurality of sequence reads each derived from a RNA molecule obtained from the test sample, filtering the plurality of sequence reads, identifying one or more candidate variants from the filtered plurality of sequence reads, determining a quality score for each of the identified one or more candidate variants, the quality score indicating a likelihood that the candidate variant is a false positive detection of a mutation in the RNA molecule, and outputting the one or more candidate variants having a quality score greater than a threshold quality score.

Abstract: A system and method for facilitating users to obtain location information in a virtual space is disclosed. Query items may be offered to sell to the users. Upon user activation of the query items, identification information identifying target entities may be obtained from the users. Based on such identification information, location information regarding virtual space locations controlled by or associated with the target entities may be provided to the users. The provided location information may include coordinate information reflecting virtual space coordinates of such locations. In some examples, the level of detail and/or accuracy of such location information provided to the users may be based on the activated query items being specific grades and/or based on levels of the users.

Abstract: Aspects of the invention relate to methods for preparing and analyzing a sequencing library from a mixed cell-free DNA (cfDNA) sample, wherein the mixed sample includes double-stranded DNA (dsDNA), damaged dsDNA (e.g., nicked dsDNA), and single-stranded DNA (ssDNA) molecules. The subject methods facilitate the collection of information from dsDNA, ssDNA and damaged DNA (e.g., nicked DNA) molecules in a sample, thereby providing enhanced diagnostic information as compared to sequencing libraries that are prepared from dsDNA alone.

Abstract: One aspect of the disclosure relates to providing players of an online game the option of performing one or more activities external to the online game instead of spend virtual currency to accomplish a specific action in the game. This option is presented through an interface that creates and displays separate “offer walls” for separation actions in the game. The activities may thematically correspond to the type of action the player wants to perform.

Abstract: Aspects of the invention relate to methods for preparing and analyzing a sequencing library from a mixed cell-free DNA (cfDNA) sample, wherein the mixed sample includes double-stranded DNA (dsDNA), damaged dsDNA (e.g., nicked dsDNA), and single-stranded DNA (ssDNA) molecules. The subject methods facilitate the collection of information from dsDNA, ssDNA and damaged DNA (e.g., nicked DNA) molecules in a sample, thereby providing enhanced diagnostic information as compared to sequencing libraries that are prepared from dsDNA alone.

Abstract: A closed loop granular jamming apparatus is disclosed including a three-dimensional membrane structure filled with granular material. Fluid is evacuated from the structure which induces a jamming effect, whereas the viscosity of the granular media increases with increasing particle density. The thin membrane conforms to the shape of the granular material. Decreasing enclosed volume and increasing packing density prevents particles from distributing within the confined space, inducing the aggregate to behave as a solid. In the jammed state, the apparatus is resistive to force and change of shape. The apparatus is returned to the unjammed state by releasing the vacuum. The size and shape of the apparatus may be repeatedly adjusted by alternating between the jammed and unjammed states. The closed loop granular jamming apparatus may include toroidal and cylindrical shapes with articulating inserts and compliant spines.

Abstract: A kit of educational building blocks includes a first set of amino acid side chain building blocks, each amino acid side chain building block corresponding to a distinct one of 20 distinct amino acid side chains, a second set of identical amino end building blocks, each amino end building block having a first end configured to removably engage with the amino acid side chain building blocks to form an amino end-side chain block combination, and a third set of identical acid end building blocks, each acid end building block having a first end configured to removably engage with amino end-side chain block combination to produce an amino acid building block assembly. The first, second, and third set of blocks are configured so that a plurality of amino acid building block assemblies can be linked to one another so as to model a series of linked amino acids in a protein.

Abstract: System and method for providing cross-game virtual containers in online games are disclosed. Virtual items usable in multiple online games may be packaged in a cross-game virtual container. Instances of cross-game virtual container may be presented for purchase by user in a virtual store. The price of a given instance of cross-game virtual container may be set as a fraction of the total of the individual prices of the virtual items in the given instance of cross-game virtual container. After an activation of a purchased instance of cross-game virtual container by a user in one of the online games, virtual items in the purchased instance of cross-game virtual container may be made available for access to the user in respective online games. In some examples, a notification may be generated for informing the user of the availability of the virtual items in the activated instance of cross-game virtual container.

Abstract: A system and method for providing virtual items to users of an online game operated in a virtual space. Multiple users may participate in affiliations or alliances of discrete groups of users in an online game and may access the online game through client computing platforms associated with the users. The affiliations may have affiliation game units associated with affiliations which provide a benefit to the members of the online game. Affiliation members may cumulatively obtain affiliation game units and/or upgrade affiliation game units by providing one or more virtual items. Upgrading affiliation game units may require the cooperation of multiple members of the affiliation.

Abstract: Example implementations relate to calculating a time to live (TTL). An example implementation includes receiving a transaction request containing a first time to live (TTL) from a requester. A second TTL for a transaction response may be computed, and a transaction response containing the second TTL may be transmitted.

Abstract: A method for displaying a menu based on a service environment analysis in a content execution apparatus is disclosed. In accordance with the method for displaying the menu based on the service environment analysis in the content execution apparatus of the present invention, a menu is displayed according to a menu information extracted from a storage media, wherein services available to a user from a content execution apparatus is determined and the menu information is updated according to the availability of services.

Abstract: Techniques are described for providing location-based information and functionality to people and computing devices in various ways. In at least some situations, the techniques include enabling multiple people in a common geographic area to interact in various ways, such as via devices capable of communications (e.g., cellular telephones, computing devices with wired and/or wireless communications capabilities, etc.), while in other situations at least some users who are remote from a particular geographic area may be allowed to intercommunicate with one or more other users or other entities in or related to that geographic area. In addition, the techniques include enabling the creation and maintenance of location-based virtual groups of users (also referred to as “clouds”), such as for users of mobile and/or fixed-location devices. Such clouds may enable various types of interactions between group members, and may be temporary and/or mobile.

Abstract: A system and method for facilitating game action time requirement suspension in an online game are disclosed. Instances of time requirement suspension items may be offered for purchase in an online store associated with the online game. A given time requirement suspension item may be configured to reduce time requirements (e.g., wait-period) for game actions requested by a player during a corresponding time period subsequent to the activation of the instance of the requirement suspension item by the player. The player may activate a purchased instance of the requirement suspension item in the online game to reduce the time requirements for the game actions requested by the player during the time period.

Abstract: The disclosure relates to facilitating presentation of a combination of virtual units as a single entity during a battle in an online game. A user may be in control of and/or be associated with a first set of virtual units in the game space of the online game. Some of the virtual units of the user may be involved in a battle facilitated in the game space. A plurality of the virtual units controlled by and/or associated with the user may be combined as a single virtual entity, such that the plurality of virtual units is portrayed in the view of the game space of the online game as the single virtual entity. The attributes of the single virtual entity in the game space may be dictated by the collective set of attributes of the respective virtual units of the plurality of virtual units combined as the single virtual entity.

Abstract: A system and method for providing virtual items to users of an online game operated in a virtual space. Multiple users may participate in affiliations or alliances of discrete groups of users in an online game and may access the online game through client computing platforms associated with the users. The affiliations may have affiliation game units associated with affiliations which provide a benefit to the members of the online game. Affiliation members may cumulatively obtain affiliation game units and/or upgrade affiliation game units by providing one or more virtual items. Upgrading affiliation game units may require the cooperation of multiple members of the affiliation.

Abstract: A system and method for temporarily altering the determination of gameplay metric values in a game space, and distributing awards based on the relative change in gameplay metric values during the temporary time.

Abstract: A system and method for facilitating a cross-game competitive event are disclosed. The cross-game competitive event may measure user performance in multiple online games during an event time period. For such measurement, the cross-game competitive event may be associated with an event metric. The event metric may correspond to gameplay metrics for users of the multiple online games. The value of the event metric may be determined for a given user based on aggregation of changes in the values of gameplay metrics in the multiple online games within the event time period. An award may be distributed to the given user based on the event metric value determined for the given user upon conclusion of the cross-game competitive event.