Abstract: Systems and methods are provided for evaluating composition of a first file representing a document to be evaluated. An evaluation method transforms the first file to a second file. The second file includes a plurality of objects corresponding to the composition of the first file. The evaluation method also determines parameters based on the plurality of objects; evaluates the parameters based on a plurality of composition rules provided by a rule engine; generates evaluation findings and stores the evaluation findings; and generates an evaluation conclusion based on the evaluation findings. The evaluation conclusion indicates compliance of the document according to the composition rules.

Abstract: Methods and devices are disclosed herein that generally involve applying thermal therapy to tissue (e.g., localized cooling or heating of tissue), and in particular applying thermal therapy to the spinal canal, tissue disposed within the spinal canal, and/or nerve roots extending from the spinal canal. In some embodiments, tissue can be cooled or heated by implanting or positioning a thermal device in proximity to the targeted tissue. A number of exemplary thermal devices are disclosed, including bone anchors, inserts for use with bone anchors, K-wires, bone anchor extensions or towers, cross-connectors, spinous process plates, spinal rods, pedicle markers, bone taps, drill bits, bone plugs, bone plates, clamps, interbody or disc implants, thermal pads, and tubing loops. The thermal device can be left in place following surgery to facilitate application of post-surgical thermal therapy. In some embodiments, the thermal device can be removed post-surgery in a minimally- or non-invasive manner.

Abstract: Methods and devices are disclosed herein that generally involve applying thermal therapy to tissue (e.g., localized cooling or heating of tissue), and in particular applying thermal therapy to the spinal canal, tissue disposed within the spinal canal, and/or nerve roots extending from the spinal canal. In some embodiments, tissue can be cooled or heated by implanting or positioning a thermal device in proximity to the targeted tissue. A number of exemplary thermal devices are disclosed, including bone anchors, inserts for use with bone anchors, K-wires, bone anchor extensions or towers, cross-connectors, spinous process plates, spinal rods, pedicle markers, bone taps, drill bits, bone plugs, bone plates, clamps, interbody or disc implants, thermal pads, and tubing loops. The thermal device can be left in place following surgery to facilitate application of post-surgical thermal therapy. In some embodiments, the thermal device can be removed post-surgery in a minimally- or non-invasive manner.

Abstract: Methods and systems of maintaining, evaluating, and providing therapy to a lung ex vivo. The methods and systems involve positioning the lung in an ex vivo perfusion circuit; circulating a perfusion fluid through the lung, the fluid entering the lung through a pulmonary artery interface and leaving the lung through a left atrial interface; and ventilating the lung by flowing a ventilation gas through a tracheal interface. Maintaining the lung for extended periods involves causing the lung to rebreath a captive volume of air, and reaching an equilibrium state between the perfusion fluid and the ventilation gas. Evaluating the gas exchange capability of the lung involves deoxygenating the perfusion fluid and measuring a time taken to reoxygenate the perfusion fluid by ventilating the lung with an oxygenation gas.

Abstract: A network, such as a computer network, is disclosed. The network has a plurality of nodes and includes a first node for storing pieces of a digital object and having a storage. A plurality of connections are present between the first node and the plurality of nodes. The first node has a requester for requesting one or more pieces of the digital object, a transmitter for transferring one or more pieces of the digital object to at least one further node among the plurality of nodes, a receiver for receiving content availability messages from at least some of the plurality of nodes, and a sender for sending a limited content availability message to at least one further node among the plurality of nodes. The limited content availability message indicates a subset but not all of the pieces of the digital object available through the first node.

Abstract: A method for effecting neuromuscular mechanisms for treatment of specific non-restless leg syndrome, non-restless arms, and non-foot and leg cramps diseases, conditions, and/or illnesses utilizes a device for applying positive pressure to specific areas of the foot. Slight variations to the positioning and/or patient application of the device may be adopted to increase benefits for specific diseases, conditions, or illnesses. Such variations can include frequency or time intervals of use and variations in pressure and positioning of pressure.

Abstract: The invention generally relates to systems, methods, and devices for ex vivo organ care. More particularly, in various embodiments, the invention relates to caring for a liver ex vivo at physiologic or near-physiologic conditions.

Abstract: Streamable data is streamed from user queues of streamable data to a plurality of devices associated with a plurality of users, each device being associated with a single user. Each user has its own user queue of streamable data. A rule set is created and stored for each user that defines one or more types of streamable data that each user requests to receive on the user's device. One of the types of streamable data are traffic alerts regarding roadway conditions for specific roadways, wherein each of the traffic alerts is associated with a geographic location. A traffic alert is streamed to a user device when the user device is detected as being at the geographical location of the traffic alert.

Abstract: A compose form for drafting a message is presented inline within a window along with a message list. For example, instead of overlaying the message application's user interface (UI) with a new window for composing a message, the compose form is displayed within a portion of the window reserved for viewing content of messages. While composing the message using the compose form, the rest of the message application's UI remains visible and accessible to the user. For example, the user may navigate to another folder and/or move to another message/conversation by interacting with the tree view/message list view. A draft of the message being composed may be automatically saved when the user navigates away from the compose form (e.g. by selecting another conversation in the list view).

Abstract: Provided herein are methods of administering a 5,5-fused heteroarylene hepatitis C virus inhibitor compound or an isotopic variant thereof, or a pharmaceutically acceptable salt or solvate thereof; for treating or preventing hepatitis C virus infection in a subject.

Abstract: A system encrypts digital content data with a key of a content encryption key (CEK) pair and CEK related share data available to an end user station including a source for generating source encrypted data including content data. The share data is encrypted with a first key of a second encryption key pair associated with a targeted intermediate station including a processor receiving source encrypted data and being in data communication with a portable storage device associated with the end user station, which is associated with a third encryption key pair. The processor generates intermediate station encrypted data by decrypting encrypted share data using a key of the second key pair and encrypting resulting decrypted data using a key of the third key pair. A reconstruction processor uses an algorithm and input share data to reconstruct the CEK. A decryption processor uses the reconstructed CEK to decrypt encrypted content data.

Abstract: A system for transferring driver profile settings has a communication interface, processor, storage device, and program in the storage device. The communication interface allows for network communications. The processor couples to the interface. Execution of the program from storage by the processor configures the system to perform functions. The system allows for transfer of a driver profile from the storage device to a vehicle for application on the vehicle. The driver profile specifies one or more preference settings for one or more configurable components of a vehicle.

Abstract: A compose form for drafting a message is presented inline within a window along with a message list. For example, instead of overlaying the message application's user interface (UI) with a new window for composing a message, the compose form is displayed within a portion of the window reserved for viewing content of messages. While composing the message using the compose form, the rest of the message application's UI remains visible and accessible to the user. For example, the user may navigate to another folder and/or move to another message/conversation by interacting with the tree view/message list view. A draft of the message being composed may be automatically saved when the user navigates away from the compose form (e.g. by selecting another conversation in the list view).

Abstract: Structural elements comprised of functionalized material in a rapidly setting resin. The structural elements are rapidly deployable and arranged as structures that provide ballistic and impact resistance. The structures are fabricated using specific molds that shape a specific rapid cure resin-filler mixture.

Abstract: Methods and devices are disclosed herein that generally involve applying thermal therapy to tissue (e.g., localized cooling or heating of tissue), and in particular applying thermal therapy to the spinal canal, tissue disposed within the spinal canal, and/or nerve roots extending from the spinal canal. In some embodiments, tissue can be cooled or heated by implanting a malleable or deformable thermal device in proximity to the targeted tissue. The thermal device can be left in place following surgery to facilitate application of post-surgical thermal therapy. In some embodiments, the thermal device can be removed post-surgery in a minimally- or non-invasive manner. The thermal device can be connectionless or can include penetrable regions, pre-attached tubing, or detachable connectors to facilitate application of cooling or heating means to the device. Methods are disclosed for utilizing thermal devices and for carrying out various treatment regimens that involve cooling or heating tissue using such devices.

Abstract: Methods and devices are disclosed herein that generally involve applying thermal therapy to tissue (e.g., localized cooling or heating of tissue), and in particular applying thermal therapy to the spinal canal, tissue disposed within the spinal canal, and/or nerve roots extending from the spinal canal. In some embodiments, tissue can be cooled or heated by implanting or positioning a thermal device in proximity to the targeted tissue. A number of exemplary thermal devices are disclosed, including bone anchors, inserts for use with bone anchors, K-wires, bone anchor extensions or towers, cross-connectors, spinous process plates, spinal rods, pedicle markers, bone taps, drill bits, bone plugs, bone plates, clamps, interbody or disc implants, thermal pads, and tubing loops. The thermal device can be left in place following surgery to facilitate application of post-surgical thermal therapy. In some embodiments, the thermal device can be removed post-surgery in a minimally- or non-invasive manner.

Abstract: A system for transferring driver profile settings has a communication interface, processor, storage device, and program in the storage device. The communication interface allows for network communications. The processor couples to the interface. Execution of the program from storage by the processor configures the system to perform functions. The system allows for transfer of a driver profile from the storage device to a vehicle for application on the vehicle. The driver profile specifies one or more preference settings for one or more configurable components of a vehicle.

Abstract: Systems and methods of the present disclosure relate to optimizing a content campaign of a computer network. A data processing system (“system”) can receive and parse a first content item of the content campaign from a content provider via a computer network to identify a logical element, which can include at least one of a verb, noun and temporal language. The system can identify a variant of the logical element to generate a second content item that includes the variant and maintains the syntactic integrity of the first content item. The system can provide at least one of the first content item and the second item for display on at least one web page responsive to receiving one or more requests for content. The system can analyze a performance metric for each of the first content item and the second content item to determine an optimum performing content item.

Abstract: The present invention provides methods and compositions for improving the efficiency of nucleic acid amplification reactions. The invention encompasses hybrid polymerases that show increased processivity over wild type polymerases as well as decreased exonucleases activity. The invention also encompasses methods, compositions and kits for conducting nucleic acid synthesis and amplification reactions in which non-specific amplification of primers is reduced.