Patents by Inventor John Yan
John Yan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210008040Abstract: The present invention provides a pharmaceutical composition comprising a pharmaceutically acceptable excipient and a compound of the formula: wherein R1, R2, R3, R5, R6, R8, M1, M2, M3, M4, M5, M6 and M7 are each independently a member selected from the group consisting of H, C1-6 alkyl, —OH and C1-6 hydroxyalkyl; R4, R7 and R9 are each independently selected from the group consisting of C1-6 alkoxy and OH; R10 is a member selected from the group consisting of H, —OH, —OP(O)Me2, —O—(CH2)n—OH and —O—(CH2)m—O—(CH2)o—CH3, wherein subscripts n and m are each independently from 2 to 8 and subscript o is from 1 to 6; each of L1 and L4 are independently selected from the group consisting of: wherein each M8 is independently a member selected from the group consisting of C1-6 alkyl, OH and C1-6 hydroxyalkyl; each of L2 and L3 are independently selected from the group consisting of: and salts, hydrates, isomers, metabolites, N-oxides and prodrugs thereof.Type: ApplicationFiled: May 20, 2020Publication date: January 14, 2021Applicant: Elixir Medical CorporationInventors: John Yan, Xiaoxia Zheng, Vinayak D. Bhat
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Publication number: 20200405513Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provide high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold is typically formed from non-degradable material and will be modified to expand and/or uncage after deployment.Type: ApplicationFiled: September 10, 2020Publication date: December 31, 2020Applicant: Elixir Medical CorporationInventors: Motasim Sirhan, John Yan, Vinayak Bhat, Joseph Paraschac, Brett Cryer, Benjamyn Serna
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Patent number: 10786374Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provides high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold may be formed from degradable material, or may be formed from non-degradable material and will be modified to expand and/or uncage after deployment.Type: GrantFiled: July 22, 2019Date of Patent: September 29, 2020Assignee: Elixir Medical CorporationInventors: Motasim Sirhan, John Yan, Vinayak Bhat, Joseph Paraschac, Brett Cryer, Benjamyn Serna
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Publication number: 20200253757Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provide high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold is typically formed from non-degradable material and will be modified to expand and/or uncage after deployment.Type: ApplicationFiled: February 10, 2020Publication date: August 13, 2020Applicant: Elixir Medical CorporationInventors: Motasim Sirhan, John Yan, Vinayak Bhat, Joseph Paraschac, Brett Cryer, Benjamyn Serna
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Patent number: 10695327Abstract: A pharmaceutical composition comprising a pharmaceutically acceptable excipient and a compound of the formula: wherein R1, R2, R3, R5, R6, R8, M1, M2, M3, M4, M5, M6 and M7 are each independently a member selected from the group consisting of H, C1-6 alkyl, OH and C1-6 hydroxyalkyl; R4, R7 and R9 are each independently selected from the group consisting of C1-6 alkoxy and OH; R10 is a member selected from the group consisting of H, —OH, —OP(O)Me2, —O—(CH2)n—OH and —O—(CH2)m—O—(CH2)o—CH3, wherein subscripts n and m are each independently from 2 to 8 and subscript o is from 1 to 6; each of L1 and L4 are independently selected from the group consisting of: wherein each M8 is independently a member selected from the group consisting of C1-6 alkyl, OH and C1-6 hydroxyalkyl; each of L2 and L3 are independently selected from the group consisting of: and salts, isomers, or N-oxides thereof.Type: GrantFiled: October 8, 2018Date of Patent: June 30, 2020Assignee: Elixir Medical CorporationInventors: John Yan, Xiaoxia Zheng, Vinayak D. Bhat
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Publication number: 20200188142Abstract: Devices and methods are provided for an implantable medical device which is degradable over a clinically relevant period of time. The medical devices may have the form of implants, graft implants, vascular implants, non vascular implants, wound closure implants, sutures, drug delivery implants, biologic delivery implants, urinary tract implants, inter-uterine implants, organ implants, bone implants including bone plates, bone screws, dental implants, spinal disks, or the like. In preferred embodiments, the implantable medical device comprises an implantable luminal prosthesis, such as vascular and non-vascular stents and stents grafts.Type: ApplicationFiled: June 5, 2019Publication date: June 18, 2020Applicant: Elixir Medical CorporationInventors: John Yan, Motasim Sirhan, Brett Cryer, Vinayak Bhat
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Publication number: 20200146854Abstract: A system for reshaping a valve annulus includes an elongate template having a length along a longitudinal axis and at least one concavity in a generally lateral direction along said length. The pre-shaped template is positioned against at least a region of an inner peripheral wall of the valve annulus, and at least one anchor on the template is advanced into a lateral wall of the valve annulus to reposition at least one segment of the region of the inner peripheral wall of the valve annulus into said concavity. In this way, a peripheral length of the valve annulus can be foreshortened and/or reshaped to improve coaption of the valve leaflets and/or to eliminate or decrease regurgitation of a valve.Type: ApplicationFiled: January 10, 2020Publication date: May 14, 2020Applicant: Elixir Medical CorporationInventors: Motasim Sirhan, Vinayak Bhat, Joseph Paraschac, Benjamyn Serna, John Yan, Brett Cryer
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Publication number: 20200093619Abstract: The disclosure provides biodegradable implantable devices such as a stent comprising a biodegradable polymeric wherein the polymeric material is treated to control crystallinity and/or Tg. The stent is capable to expand at body temperature in a body lumen from a crimped configuration to a deployed diameter and have sufficient strength to support a body lumen.Type: ApplicationFiled: February 20, 2018Publication date: March 26, 2020Applicant: Elixir Medical CorporationInventors: Xiaoxia Zheng, John Yan, Vinayak Bhat
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Publication number: 20190365548Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provides high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold may be formed from degradable material, or may be formed from non-degradable material and will be modified to expand and/or uncage after deployment.Type: ApplicationFiled: July 22, 2019Publication date: December 5, 2019Applicant: Elixir Medical CorporationInventors: Motasim Sirhan, John Yan, Vinayak Bhat, Joseph Paraschac, Brett Cryer, Benjamyn Serna
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Patent number: 10491184Abstract: Systems, methods, and computer-readable media are disclosed for common mode filters with inverted inductive ground structures. In one embodiment, an example printed circuit board may have a first layer with a pair of differential transmission lines, and a common mode filter embedded in the printed circuit board. The common mode filter may include a signal reference structure and an inductive ground structure. The signal reference structure may include a first rectangular portion, and a second rectangular portion having the same dimensions. The second rectangular portion may be separated from the first rectangular portion by a distance. The inductive ground structure may include a first cell having a first conductive line coupled to a first side of the first rectangular portion and a first edge of the common mode filter, and a second cell having a second conductive line coupled to a first side of the second rectangular portion and the first edge.Type: GrantFiled: October 12, 2017Date of Patent: November 26, 2019Assignee: Amazon Technologies, Inc.Inventor: John Yan
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Publication number: 20190275013Abstract: The present invention provides a pharmaceutical composition comprising a pharmaceutically acceptable excipient and a compound of the formula: wherein R1, R2, R3, R5, R6, R8, M1, M2, M3, M4, M5, M6 and M7 are each independently a member selected from the group consisting of H, C1-6 alkyl, OH and C1-6 hydroxyalkyl; R4, R7 and R9 are each independently selected from the group consisting of C1-6 alkoxy and OH; R10 is a member selected from the group consisting of H, —OH, —OP(O)Me2, —O—(CH2)n—OH and —O—(CH2)m—O—(CH2)o—CH3, wherein subscripts n and m are each independently from 2 to 8 and subscript o is from 1 to 6; each of L1 and L4 are independently selected from the group consisting of: wherein each M8 is independently a member selected from the group consisting of C1-6 alkyl, OH and C1-6 hydroxyalkyl; each of L2 and L3 are independently selected from the group consisting of: and salts, hydrates, isomers, metabolites, N-oxides and prodrugs thereof.Type: ApplicationFiled: October 8, 2018Publication date: September 12, 2019Applicant: Elixir Medical CorporationInventors: John Yan, Xiaoxia Zheng, Vinayak D. Bhat
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Patent number: 10383750Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provides high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold may be formed from degradable material, or may be formed from non-degradable material and will be modified to expand and/or uncage after deployment.Type: GrantFiled: March 18, 2019Date of Patent: August 20, 2019Assignee: Elixir Medical CorporationInventors: Motasim Sirhan, John Yan, Vinayak Bhat, Joseph Paraschac, Brett Cryer, Benjamyn Serna
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Publication number: 20190231564Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provides high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold may be formed from degradable material, or may be formed from non-degradable material and will be modified to expand and/or uncage after deployment.Type: ApplicationFiled: March 18, 2019Publication date: August 1, 2019Applicant: Elixir Medical CorporationInventors: Motasim Sirhan, John Yan, Vinayak Bhat, Joseph Paraschac, Brett Cryer, Benjamyn Serna
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Patent number: 10350093Abstract: Devices and methods are provided for an implantable medical device which is degradable over a clinically relevant period of time. The medical devices may have the form of implants, graft implants, vascular implants, non vascular implants, wound closure implants, sutures, drug delivery implants, biologic delivery implants, urinary tract implants, inter-uterine implants, organ implants, bone implants including bone plates, bone screws, dental implants, spinal disks, or the like. In preferred embodiments, the implantable medical device comprises an implantable luminal prosthesis, such as vascular and non-vascular stents and stents grafts.Type: GrantFiled: December 23, 2015Date of Patent: July 16, 2019Assignee: Elixir Medical CorporationInventors: John Yan, Motasim Sirhan, Brett Cryer, Vinayak Bhat
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Patent number: 10271976Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provides high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold may be formed from degradable material, or may be formed from non-degradable material and will be modified to expand and/or uncage after deployment.Type: GrantFiled: July 18, 2018Date of Patent: April 30, 2019Assignee: Elixir Medical CorporationInventors: Motasim Sirhan, John Yan, Vinayak Bhat, Joseph Paraschac, Brett Cryer, Benjamyn Serna
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Publication number: 20190070334Abstract: Luminal prostheses comprise scaffolds having coatings adhered to at least a portion of their outer surfaces. The surfaces are modified to enhance binding of the coatings. For example, the surfaces may be microblasted, laser treated, chemically etched, exposed to plasma, or exposed to a corona discharge, allowing a polymeric coating to adhere to the scaffold more tightly than in the absence of the surface modification. The coatings can be used to deliver therapeutic or other agents dispersed therein.Type: ApplicationFiled: March 2, 2018Publication date: March 7, 2019Applicant: Elixir Medical CorporationInventors: John Yan, Howard Huang, Vinayak D. Bhat
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Publication number: 20180360628Abstract: A biodegradable stent prosthesis formed from a degradable material, having a plurality of luminal, abluminal, and side surface regions, wherein a surface portion extending between the abluminal and luminal surface region of at least some structural elements is convex.Type: ApplicationFiled: December 8, 2017Publication date: December 20, 2018Applicant: Elixir Medical CorporationInventors: John Yan, Vinayak Bhat
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Patent number: 10123996Abstract: A pharmaceutical composition comprising a pharmaceutically acceptable excipient and a compound of the formula: wherein R1, R2, R3, R5, R6, R8, M1, M2, M3, M4, M5, M6 and M7 are each independently a member selected from the group consisting of H, C1-6 alkyl, OH and C1-6 hydroxyalkyl; R4, R7 and R9 are each independently selected from the group consisting of C1-6 alkoxy and OH; R10 is a member selected from the group consisting of H, —OH, —OP(O)Me2, —O—(CH2)n—OH and —O—(CH2)m—O—(CH2)o—CH3, wherein subscripts n and m are each independently from 2 to 8 and subscript o is from 1 to 6; each of L1 and L4 are independently selected from the group consisting of: wherein each M8 is independently a member selected from the group consisting of C1-6 alkyl, OH and C1-6 hydroxyalkyl; each of L2 and L3 are independently selected from the group consisting of: and salts, isomers, or N-oxides thereof.Type: GrantFiled: June 13, 2016Date of Patent: November 13, 2018Assignee: Elixir Medical CorporationInventors: John Yan, Xiaoxia Zheng, Vinayak D. Bhat
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Publication number: 20180318113Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provides high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold may be formed from degradable material, or may be formed from non-degradable material and will be modified to expand and/or uncage after deployment.Type: ApplicationFiled: July 18, 2018Publication date: November 8, 2018Applicant: Elixir Medical CorporationInventors: Motasim Sirhan, John Yan, Vinayak Bhat, Joseph Paraschac, Brett Cryer, Benjamyn Serna
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Patent number: 10076431Abstract: A stent (scaffold) or other luminal prosthesis comprising circumferential structural elements which provides high strength after deployment and allows for scaffold to uncage, and/or allow for scaffold or luminal expansion thereafter. The circumferential scaffold may be formed from degradable material, or may be formed from non-degradable material and will be modified to expand and/or uncage after deployment.Type: GrantFiled: March 14, 2018Date of Patent: September 18, 2018Assignee: Elixir Medical CorporationInventors: Motasim Sirhan, John Yan, Vinayak Bhat, Joseph Paraschac, Brett Cryer, Benjamyn Serna