Abstract: Antibodies that bind SARS-CoV spike protein, SARS-CoV-2 spike protein, and methods of using same for treating or preventing conditions associated with SARS or COVID-19 and for detecting SARS-CoV or SARS-CoV-2.

Abstract: There is disclosed a method of operating a wireless device in a wireless communication network. The method includes transmitting a measurement report, the measurement report being indicative of a combination of a first set of measurement results, the first set of measurement results at least comprising a first measurement result pertaining to first reference signaling received by the wireless device and a second measurement result pertaining to second reference signaling received by the wireless device. The disclosure also pertains to related devices and methods.

Abstract: A payload of drug conjugated to a targeting ligand specifically designed to deliver to exhausted CAR T cells to rejuvenate these CAR T cells is provided herein. The targeted CAR T cells are modified with a fusion receptor which can bind to the targeting ligand and internalize the conjugated payload of drug to execute its regulatory function to exhausted CAR T cell.

Abstract: A method for estimating a battery state of charge may include determining a first estimated state of charge and a first estimated accuracy of the state of charge using a first estimation approach, determining a second estimated state of charge and a second estimated accuracy of the state of charge using a second estimation approach, and estimating the battery state of charge based on the first estimated state of charge, the first estimated accuracy of the state of charge, the second estimated state of charge, and the second estimated accuracy of the state of charge.

Abstract: Described herein is a building panel comprising a first major exposed surface opposite a second major exposed surface, the building panel comprising: a body having a first major surface opposite a second major surface and a plurality of perforations extending from the first major surface toward the second major surface; a flame-retardant coating atop the first major surface of the body and extending into the plurality of perforations, the coating comprising a silicate compound and an amphoteric surfactant; and wherein the building panel has an airflow resistance of less than about 12,000 rayls as measured between the first major exposed surface and the second major exposed surface.

Abstract: A data set can be analyzed for the presence of sensitive data using type-specific validation mechanisms to test data within the data set that superficially matches a corresponding data type format. In general, a type-specific validation mechanism may be applied to data segments within the data set when they match the data type format, and used to cumulatively build a statistical inference about whether the data set contains the corresponding data type. This technique may usefully be applied in a range of security contexts, such as characterizing data at rest or detecting leakage of sensitive data during a data transmission.

Abstract: An electric machine with a low profile retention assembly for retention of a stator core is disclosed. A first housing houses the stator core. The first housing has an axial end face with a circumferentially extending, shaped profile having recessed portions that project axially inward alternating with non-recessed portions. A portion of the stator core extends axially out from the recessed portions. A core retention spring is disposed circumferentially at the axial end face of the first housing. The core retention spring has direct contact with the portion of the stator core that extends axially out from the recessed portions of the first housing and the shaped profile of the housing. The core retention spring pushes against the portion of the stator core that extends that extends axially out from the first housing, imparting one or more of an axial load and radial load into the stator core.

Abstract: The present application provides, in some aspects, methods of identifying a condensate of interest associated with a el disease. Also provided are methods of identifying a marker for identifying a condensate of interest associated with a disease. In other aspects, provided herein are methods of identifying a therapeutic agent useful for treating a disease via the identified condensate of interest.

Abstract: A method for controlling a near eye display system, includes obtaining an eye movement of a user wearing the near eye display system using an eye tracking sensor of the near eye display system, determining a target area of a display of the near eye display system based on the eye movement of the user, the target area of the display being an area that the user is looking at, and controlling a brightness of the target area of the display of the near eye display system to cause a size of a pupil of the user to be in a predetermined range.

Abstract: A method and apparatus for transmitting uplink control information (UCI) for Long Term Evolution-Advanced (LTE-A) using carrier aggregation is disclosed. Methods for UCI transmission in the uplink control channel, uplink shared channel or uplink data channel are disclosed. The methods include transmitting channel quality indicators (CQI), precoding matrix indicators (PMI), rank indicators (RI), hybrid automatic repeat request (HARQ) acknowledgement/non-acknowledgement (ACK/NACK), channel status reports (CQI/PMI/RI), source routing (SR) and sounding reference signals (SRS). In addition, methods for providing flexible configuration in signaling UCI, efficient resource utilization, and support for high volume UCI overhead in LTE-A are disclosed.

Abstract: Disclosed are compounds having the formula: wherein q, r, s, A, B, C, RA1, RA2, RB1, RB2, RC1, RC2, R3, R4, R5, R6, R14, R15, R16, and R17, are as defined herein, or a tautomer thereof, or a salt, particularly a pharmaceutically acceptable salt, thereof.

Abstract: The present invention is directed to cinnolinyl and quinolinyl pyrazol-4-yl-pyridine compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which M4 muscarinic acetylcholine receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.

Abstract: A system for mask design repair may develop a simulation-based model of a layer thickness after one or more process steps for fabricating features on a sample, develop a transformed model of the fabrication process that emulates the simulation-based model and has a faster evaluation speed than the simulation-based model, and where the inputs to the transformed model include the input mask design, and where the outputs of the transformed model include one or more output parameters associated with fabrication of the input mask design as well as one or more sensitivity metrics describing sensitivities of the one or more output parameters to variations of the input mask design. The system may further receive a candidate mask design and generate a repaired mask design based on the transformed model and the candidate mask design.

Abstract: In order to improve both spatial resolution and sensitivity for brain research and clinical activity, we have designed a combined PET/MRI insert for brain scanning, referred to herein as a “BrainPET insert” that can be fit onto and into a suitable MRI system. The BrainPET Insert comprises, in order, a receive (Rx) coil positioned within and adjacent to a transmit (Tx) coil and a PET ring, wherein both the Rx coil and the Tx coil are within the PET ring.

Abstract: A surgical instrument, has an end effector that includes an ultrasonic blade, and a clamp arm that moves relative to the ultrasonic blade from an opened position toward an intermediate position and a closed position. The clamp arm is offset from the ultrasonic blade to define a predetermined gap in the intermediate position between the opened position and the closed position. A clamp arm actuator connects to the clamp arm and moves from an opened configuration to a closed configuration to direct the clamp arm from the opened position toward the intermediate position and the closed position. A spacer connects with the clamp arm to inhibit movement of the clamp arm from the intermediate position toward the closed position for maintaining the predetermined gap between the clamp arm and the ultrasonic blade.

Abstract: An approach for facilitating mechanical and electrical connection of electric machines and electrical components in an electrical system using connectors with quick connect/disconnect electrical connectors is disclosed. Each quick connect/disconnect electrical connector can be placed on the end of an electrical power distribution cable that connects with an electric machine or electrical component. The electric machines and electrical components and the electrical power distribution cables can have hollow coolant passages formed therein to receive cooling fluid from a cooling device for direct cooling of the electric machines, electrical components and the electrical power distribution cables.

Abstract: Wirelessly powered photodynamic therapy devices are disclosed and systems and methods using such devices are also disclosed. In an embodiment, a photodynamic therapy system comprises: an implantable illumination device comprising a light source configured to emit light having a spectrum which overlaps with an absorption peak of an absorption target and a receiver antenna coupled to the light source and configured to extract power from a radiofrequency power signal incident on the implantable illumination device; and a transmitter comprising an antenna, a powering module configured to generate a drive signal which causes the antenna to generate the radiofrequency power signal, and a dosimetry module coupled to the antenna and configured to detect a radiofrequency signal backscattered from the implantable illumination device and determine an indication of the power extracted by the implantable illumination device from the radiofrequency signal backscattered from the implantable illumination device.

Abstract: Disclosed are monoclonal antibodies, antigen binding fragments, and bi-specific antibodies that specifically bind a coronavirus spike protein, such as SARS-CoV-2. Also disclosed is the use of these antibodies for inhibiting a coronavirus infection, such as a SARS-CoV-2 infection. In addition, disclosed are methods for detecting a coronavirus, such as SARS-CoV-2, in a biological sample, using the disclosed antibodies.

Abstract: A class of pyrimidoheterocyclic compounds, and specifically disclosed is a compound represented by formula (III) or a pharmaceutically acceptable salt thereof.