Patents by Inventor Jorge Valdes
Jorge Valdes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240148284Abstract: Machine learning in an artificial pancreas is described. An artificial pancreas system may include a wearable glucose monitoring device, an insulin delivery system, and a computing device. Broadly speaking, the wearable glucose monitoring device provides glucose measurements of a person continuously. The artificial pancreas algorithm, which may be implemented at the computing device, determines doses of insulin to deliver to the person based on a variety of aspects for the purpose of maintaining the person's glucose within a target range, as indicated by those glucose measurements. The insulin delivery system then delivers those determined doses to the person. As the artificial pancreas algorithm determines insulin doses for the person over time and effectiveness of the insulin doses to maintain the person's glucose level in the target range is observed, an underlying model of the artificial pancreas algorithm may be updated to better determine insulin doses.Type: ApplicationFiled: November 28, 2023Publication date: May 9, 2024Inventors: Derek James Escobar, Naresh C. Bhavaraju, Gary A. Morris, Jorge Valdes
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Patent number: 11872034Abstract: Machine learning in an artificial pancreas is described. An artificial pancreas system may include a wearable glucose monitoring device, an insulin delivery system, and a computing device. Broadly speaking, the wearable glucose monitoring device provides glucose measurements of a person continuously. The artificial pancreas algorithm, which may be implemented at the computing device, determines doses of insulin to deliver to the person based on a variety of aspects for the purpose of maintaining the person's glucose within a target range, as indicated by those glucose measurements. The insulin delivery system then delivers those determined doses to the person. As the artificial pancreas algorithm determines insulin doses for the person over time and effectiveness of the insulin doses to maintain the person's glucose level in the target range is observed, an underlying model of the artificial pancreas algorithm may be updated to better determine insulin doses.Type: GrantFiled: December 7, 2020Date of Patent: January 16, 2024Assignee: DEXCOM, INC.Inventors: Derek James Escobar, Naresh C. Bhavaraju, Gary A. Morris, Jorge Valdes
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Publication number: 20230346267Abstract: Systems and methods for a continuous monitoring of analyte values received from an analyte sensor system are provided. One method for a wireless data communication between an analyte sensor system and a mobile device involves storing identification information associated with a transceiver of the analyte sensor system, the identification information entered by a user of the mobile device via a custom application running on the mobile device; causing the custom application to enter a background mode; searching for advertisement signals; receiving an advertisement signal from the transceiver; authenticating the transceiver based on the identification information; prompting the user to bring the custom application to a foreground mode; causing the custom application to request a confirmation from the user that a data connection with the transceiver is desired; receiving the confirmation from the user; and completing the data connection with the transceiver.Type: ApplicationFiled: July 5, 2023Publication date: November 2, 2023Inventors: Jose Hector HERNANDEZ-ROSAS, Shawn LARVENZ, Mark DERVAES, Indrawati GAUBA, Michael Robert MENSINGER, Eric COHEN, Brian Christopher SMITH, Jorge VALDES, Jacob S. LEACH
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Patent number: 11759517Abstract: This invention reveals the pharmaceutical composition that includes the surface antigen (HBsAg) of the hepatitis B virus (HBV) and the antigen of the nucleocapsid (or core, HBcAg) of the same virus. The HBcAg of this composition contains messenger ribonucleic acid (mRNA) at a proportion of over 45% of the total amount of ribonucleic acid (RNA) in this antigen. Because of the changes in the constitution of the antigens forming it, the composition of the invention is useful for the prevention or treatment of chronic hepatitis B. It also covers the use of this pharmaceutical composition in the production of a drug for immuno-prophylaxis or immunotherapy against HBV infection, and its use to increase the immune response against an additional antigen that is co-administered with the mixture of these antigens.Type: GrantFiled: March 8, 2022Date of Patent: September 19, 2023Assignee: CENTRO DE INGENIERÍA GENÉTICA Y BIOTECNOLOGÍAInventors: Julio César Aguilar Rubido, Yadira Lobaina Mato, Enrique Iglesias Perez, Eduardo Pentón Arias, Gerardo Enrique Guillén Nieto, Jorge Agustin Aguiar Santiago, Sonia Gonzalez Blanco, Jorge Valdes Hernandez, Mariela Vazquez Catillo
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Patent number: 11730402Abstract: Systems and methods for a continuous monitoring of analyte values received from an analyte sensor system are provided. One method for a wireless data communication between an analyte sensor system and a mobile device involves storing identification information associated with a transceiver of the analyte sensor system, the identification information entered by a user of the mobile device via a custom application running on the mobile device; causing the custom application to enter a background mode; searching for advertisement signals; receiving an advertisement signal from the transceiver; authenticating the transceiver based on the identification information; prompting the user to bring the custom application to a foreground mode; causing the custom application to request a confirmation from the user that a data connection with the transceiver is desired; receiving the confirmation from the user; and completing the data connection with the transceiver.Type: GrantFiled: June 14, 2022Date of Patent: August 22, 2023Assignee: Dexcom, Inc.Inventors: Jose Hector Hernandez-Rosas, Shawn Larvenz, Mark Dervaes, Indrawati Gauba, Michael Robert Mensinger, Eric Cohen, Brian Christopher Smith, Jorge Valdes, Jacob S. Leach
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Publication number: 20230170090Abstract: Methods and apparatus, including computer program products, are provided for processing analyte data. In some example implementations, a method may include generating glucose sensor data indicative of a host's glucose concentration using a glucose sensor; calculating a glycemic variability index (GVI) value based on the glucose sensor data; and providing output to a user responsive to the calculated glycemic variability index value. The GVI may be a ratio of a length of a line representative of the sensor data and an ideal length of the line. Related systems, methods, and articles of manufacture are also disclosed.Type: ApplicationFiled: February 1, 2023Publication date: June 1, 2023Inventors: Naresh C. BHAVARAJU, Arturo GARCIA, Phil MAYOU, Thomas A. PEYSER, Apurv Ullas KAMATH, Aarthi MAHALINGAM, Kevin SAYER, Thomas HALL, Michael Robert MENSINGER, Hari HAMPAPURAM, David PRICE, Jorge VALDES, Murrad KAZALBASH
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Publication number: 20230074617Abstract: A system is provided for monitoring analyte in a host, including a continuous analyte sensor that produces a data stream indicative of a host's analyte concentration and a device that receives and records data from the data stream from the continuous analyte sensor. In one embodiment, the device includes a single point analyte monitor, from which it obtains an analyte value, and is configured to display only single point analyte measurement values, and not any analyte measurement values associated with data received from the continuous analyte sensor. Instead, data received from the continuous analyte sensor is used to provide alarms to the user when the analyte concentration and/or the rate of change of analyte concentration, as measured by the continuous analyte sensor, is above or below a predetermined range. Data received from the continuous analyte sensor may also be used to prompt the diabetic or caregiver to take certain actions, such as to perform another single point blood glucose measurement.Type: ApplicationFiled: October 27, 2022Publication date: March 9, 2023Inventors: Jorge VALDES, David PRICE, Leif N. BOWMAN, Kristin Koenekamp COTE
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Patent number: 11600384Abstract: Methods and apparatus, including computer program products, are provided for processing analyte data. In some example implementations, a method may include generating glucose sensor data indicative of a host's glucose concentration using a glucose sensor; calculating a glycemic variability index (GVI) value based on the glucose sensor data; and providing output to a user responsive to the calculated glycemic variability index value. The GVI may be a ratio of a length of a line representative of the sensor data and an ideal length of the line. Related systems, methods, and articles of manufacture are also disclosed.Type: GrantFiled: June 18, 2019Date of Patent: March 7, 2023Assignee: Dexcom, Inc.Inventors: Naresh C. Bhavaraju, Arturo Garcia, Phil Mayou, Thomas A. Peyser, Apurv Ullas Kamath, Aarthi Mahalingam, Kevin Sayer, Thomas Hall, Michael Robert Mensinger, Hari Hampapuram, David Price, Jorge Valdes, Murrad Kazalbash
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Publication number: 20230027200Abstract: Disclosed are systems and methods for providing automated or semi-automated technical support for patients using medical devices, such as continuous glucose monitoring systems. Disclosed embodiments of automated tech support system include collection and storage of copies of streams of medical device data on multiple servers, analysis and comparison of data streams, remote tech support initiation and usage of the automated tech support system for providing improved products and services by storing and analyzing historical tech support data.Type: ApplicationFiled: September 30, 2022Publication date: January 26, 2023Inventors: Andrew Attila PAL, Leif N. BOWMAN, Eric COHEN, Basab DATTARAY, Edward DAY, Apurv Ullas KAMATH, Aarthi MAHALINGAM, Dana Denea MINOR, Scott A. MOSS, Neil S. PURI, Eli REIHMAN, Conrad WOODS, Laurie L. BERG, Jorge VALDES
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Patent number: 11510570Abstract: A system is provided for monitoring analyte in a host, including a continuous analyte sensor that produces a data stream indicative of a host's analyte concentration and a device that receives and records data from the data stream from the continuous analyte sensor. In one embodiment, the device includes a single point analyte monitor, from which it obtains an analyte value, and is configured to display only single point analyte measurement values, and not any analyte measurement values associated with data received from the continuous analyte sensor. Instead, data received from the continuous analyte sensor is used to provide alarms to the user when the analyte concentration and/or the rate of change of analyte concentration, as measured by the continuous analyte sensor, is above or below a predetermined range. Data received from the continuous analyte sensor may also be used to prompt the diabetic or caregiver to take certain actions, such as to perform another single point blood glucose measurement.Type: GrantFiled: July 7, 2020Date of Patent: November 29, 2022Assignee: Dexcom, Inc.Inventors: Jorge Valdes, David Price, Leif N. Bowman, Kristin Koenekamp Cote
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Patent number: 11491218Abstract: This invention reveals the pharmaceutical composition that includes the surface antigen (HBsAg) of the hepatitis B virus (HBV) and the antigen of the nucleocapsid (or core, HBcAg) of the same virus. The HBcAg of this composition contains messenger ribonucleic acid (mRNA) at a proportion of over 45% of the total amount of ribonucleic acid (RNA) in this antigen. Because of the changes in the constitution of the antigens forming it, the composition of the invention is useful for the prevention or treatment of chronic hepatitis B. It also covers the use of this pharmaceutical composition in the production of a drug for immuno-prophylaxis or immunotherapy against HBV infection, and its use to increase the immune response against an additional antigen that is co-administered with the mixture of these antigens.Type: GrantFiled: March 14, 2017Date of Patent: November 8, 2022Assignee: CENTRO DE INGENIERÍA GENÉTICA Y BIOTECNOLOGÍAInventors: Julio César Aguilar Rubido, Yadira Lobaina Mato, Enrique Iglesias Perez, Eduardo Pentón Arias, Gerardo Enrique Guillén Nieto, Jorge Agustín Aguiar Santiago, Sonia Gonzalez Blanco, Jorge Valdes Hernandez, Mariela Vazquez Castillo
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Publication number: 20220313122Abstract: Systems and methods for a continuous monitoring of analyte values received from an analyte sensor system are provided. One method for a wireless data communication between an analyte sensor system and a mobile device involves storing identification information associated with a transceiver of the analyte sensor system, the identification information entered by a user of the mobile device via a custom application running on the mobile device; causing the custom application to enter a background mode; searching for advertisement signals; receiving an advertisement signal from the transceiver; authenticating the transceiver based on the identification information; prompting the user to bring the custom application to a foreground mode; causing the custom application to request a confirmation from the user that a data connection with the transceiver is desired; receiving the confirmation from the user; and completing the data connection with the transceiver.Type: ApplicationFiled: June 14, 2022Publication date: October 6, 2022Inventors: Jose Hector HERNANDEZ-ROSAS, Shawn LARVENZ, Mark DERVAES, Indrawati GAUBA, Michael Robert MENSINGER, Eric COHEN, Brian Christopher SMITH, Jorge VALDES, Jacob S. LEACH
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Patent number: 11462320Abstract: Disclosed are systems and methods for providing automated or semi-automated technical support for patients using medical devices, such as continuous glucose monitoring systems. Disclosed embodiments of automated tech support system include collection and storage of copies of streams of medical device data on multiple servers, analysis and comparison of data streams, remote tech support initiation and usage of the automated tech support system for providing improved products and services by storing and analyzing historical tech support data.Type: GrantFiled: November 7, 2017Date of Patent: October 4, 2022Assignee: Dexcom, Inc.Inventors: Andrew Attila Pal, Leif N. Bowman, Eric Cohen, Basab Dattaray, Edward Day, Apurv Ullas Kamath, Aarthi Mahalingam, Dana Denea Minor, Scott A. Moss, Neil Puri, Eli Reihman, Conrad Woods, Laurie L. Berg, Jorge Valdes
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Patent number: 11399742Abstract: Systems and methods for a continuous monitoring of analyte values received from an analyte sensor system are provided. One method for a wireless data communication between an analyte sensor system and a mobile device involves storing identification information associated with a transceiver of the analyte sensor system, the identification information entered by a user of the mobile device via a custom application running on the mobile device; causing the custom application to enter a background mode; searching for advertisement signals; receiving an advertisement signal from the transceiver; authenticating the transceiver based on the identification information; prompting the user to bring the custom application to a foreground mode; causing the custom application to request a confirmation from the user that a data connection with the transceiver is desired; receiving the confirmation from the user; and completing the data connection with the transceiver.Type: GrantFiled: September 28, 2020Date of Patent: August 2, 2022Assignee: Dexcom, Inc.Inventors: Jose Hector Hernandez-Rosas, Shawn Larvenz, Mark Dervaes, Indrawati Gauba, Michael Robert Mensinger, Eric Cohen, Brian Christopher Smith, Jorge Valdes, Jacob S. Leach
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Patent number: 11295855Abstract: Disclosed are systems and methods for providing automated or semi-automated technical support for patients using medical devices, such as continuous glucose monitoring systems. Disclosed embodiments of automated tech support system include collection and storage of copies of streams of medical device data on multiple servers, analysis and comparison of data streams, remote tech support initiation and usage of the automated tech support system for providing improved products and services by storing and analyzing historical tech support data.Type: GrantFiled: November 7, 2017Date of Patent: April 5, 2022Assignee: Dexcom, Inc.Inventors: Andrew Attila Pal, Leif N. Bowman, Eric Cohen, Basab Dattaray, Edward Day, Apurv Ullas Kamath, Aarthi Mahalingam, Dana Minor, Scott A. Moss, Neil Puri, Eli Reihman, Conrad Woods, Laurie L. Berg, Jorge Valdes
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Publication number: 20220071487Abstract: Systems, devices, and methods are disclosed for wireless communication of analyte data. One such method includes, during a first interval, establishing a first connection between an analyte sensor system and a display device. During the first connection, the method includes exchanging information related to authentication between the analyte sensor system and the display device. The method includes making a determination regarding whether authentication was performed during the first interval. During a second interval, the method may include establishing a second connection between the analyte sensor system and the display device for transmission of an encrypted analyte value, and bypassing the exchanging of information related to authentication performed during the first connection.Type: ApplicationFiled: November 16, 2021Publication date: March 10, 2022Inventors: Aditya Mandapaka, Jorge Valdes, Jeffrey R. Wedekind, Eric Cohen, Douglas William Burnette, Francis William Pascual, Hari Hampapuram, Mark Dervaes, Michael Robert Mensinger
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Publication number: 20210361162Abstract: Various embodiments relate generally to continuous monitoring of analyte values received from an analyte sensor system. In some example embodiments, there is provided a method that includes receiving sensor information, calculating and storing estimated analyte measurement values based upon the received sensor information. The method also includes determining one or more communication conditions, and instructing a transceiver to advertise to a first display device in accordance with one or more communication variables based upon the one or more communication conditions. The method then transmits the estimated analyte measurement values to the at least first display device. Related systems, methods, and articles of manufacture are also described.Type: ApplicationFiled: August 2, 2021Publication date: November 25, 2021Inventors: Douglas William Burnette, Eric Cohen, Jason Halac, Hari Hampapuram, Lauren Hruby Jepson, Shawn Larvenz, Aditya Mandapaka, Michael Robert Mensinger, Jorge Valdes, Jeffrey R. Wedekind
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Patent number: 11109756Abstract: Various embodiments relate generally to continuous monitoring of analyte values received from an analyte sensor system. In some example embodiments, there is provided a method that includes receiving sensor information, calculating and storing estimated analyte measurement values based upon the received sensor information. The method also includes determining one or more communication conditions, and instructing a transceiver to advertise to a first display device in accordance with one or more communication variables based upon the one or more communication conditions. The method then transmits the estimated analyte measurement values to the at least first display device. Related systems, methods, and articles of manufacture are also described.Type: GrantFiled: December 20, 2016Date of Patent: September 7, 2021Assignee: DexCom, Inc.Inventors: Douglas William Burnette, Eric Cohen, Jason Halac, Hari Hampapuram, Lauren Hruby Jepson, Shawn Larvenz, Aditya Mandapaka, Michael Robert Mensinger, Jorge Valdes, Jeffrey R. Wedekind
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Publication number: 20210260286Abstract: Machine learning in an artificial pancreas is described. An artificial pancreas system may include a wearable glucose monitoring device, an insulin delivery system, and a computing device. Broadly speaking, the wearable glucose monitoring device provides glucose measurements of a person continuously. The artificial pancreas algorithm, which may be implemented at the computing device, determines doses of insulin to deliver to the person based on a variety of aspects for the purpose of maintaining the person's glucose within a target range, as indicated by those glucose measurements. The insulin delivery system then delivers those determined doses to the person. As the artificial pancreas algorithm determines insulin doses for the person over time and effectiveness of the insulin doses to maintain the person's glucose level in the target range is observed, an underlying model of the artificial pancreas algorithm may be updated to better determine insulin doses.Type: ApplicationFiled: December 7, 2020Publication date: August 26, 2021Inventors: Apurv Ullas Kamath, Derek James Escobar, Sumitaka Mikami, Hari Hampapuram, Benjamin Elrod West, Nathanael Paul, Naresh C. Bhavaraju, Michael Robert Mensinger, Gary A. Morris, Andrew Attila Pal, Eli Reihman, Scott M. Belliveau, Katherine Yerre Koehler, Nicholas Polytaridis, Rian Draeger, Jorge Valdes, David Price, Peter C. Simpson, Edward Sweeney
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Publication number: 20210260287Abstract: Machine learning in an artificial pancreas is described. An artificial pancreas system may include a wearable glucose monitoring device, an insulin delivery system, and a computing device. Broadly speaking, the wearable glucose monitoring device provides glucose measurements of a person continuously. The artificial pancreas algorithm, which may be implemented at the computing device, determines doses of insulin to deliver to the person based on a variety of aspects for the purpose of maintaining the person's glucose within a target range, as indicated by those glucose measurements. The insulin delivery system then delivers those determined doses to the person. As the artificial pancreas algorithm determines insulin doses for the person over time and effectiveness of the insulin doses to maintain the person's glucose level in the target range is observed, an underlying model of the artificial pancreas algorithm may be updated to better determine insulin doses.Type: ApplicationFiled: December 7, 2020Publication date: August 26, 2021Inventors: Apurv Ullas Kamath, Derek James Escobar, Sumitaka Mikami, Hari Hampapuram, Benjamin Elrod West, Nathanael Paul, Naresh C. Bhavaraju, Michael Robert Mensinger, Gary A. Morris, Andrew Attila Pal, Eli Reihman, Scott M. Belliveau, Katherine Yerre Koehler, Nicholas Polytaridis, Rian Draeger, Jorge Valdes, David Price, Peter C. Simpson, Edward Sweeney