Abstract: An apparatus, program product and method in which application program-specified resource allocation and allocation strength preferences are used to allocate hardware resources from a computer for that application program. The resource allocation preference is used to allocate hardware resources for the application program, while the allocation strength preference is used to determine whether to allocate alternate hardware resources when the resource allocation preference specified by the application program cannot be met.

Abstract: A filler neck closure system includes a capless fuel tank filler neck and a closure. The closure is coupled to the capless fuel tank filler neck to close an opening into the fuel tank filler neck.

Abstract: The present teachings provide compounds of formula I and their pharmaceutically acceptable salts, hydrates, and esters, wherein R1, R2, and X are as defined herein. The present teachings also provide methods of making the compounds of formula I, and methods of treating autoimmune and inflammatory diseases by administering a therapeutically effective amount of a compound or compounds of formula I to a mammal including a human.

Abstract: A method of fabricating a photonic crystal or photonic band gap optical fiber comprises providing a preform that includes a plurality of holes in an outer diameter, wherein the holes extend from a first end of a preform to a second end of the preform, and forming at least one radially inwardly-extending slot within the preform such that the slot intersects at least some of the holes, wherein the slot does not intersect at least one hole. The method also includes establishing a first pressure in the holes intersected by the slot by introducing the first pressure to the slot, and establishing a second pressure in the at least one hole not intersected by the slot by introducing the second pressure to an end of the at least one hole not intersected by the slot. The method further includes drawing the preform into a fiber while independently controlling the first and second pressures.

Abstract: An inclined hearth combustor which generally includes a primary combustion chamber having a plurality of stepped hearths, a secondary combustion chamber in communication with the primary combustion chamber and a boiler having an inlet in communication with the secondary combustion chamber. The secondary combustion chamber includes a refractory-lined cyclone separator for removing fly ash from combustion gases exiting the primary combustion chamber and the boiler inlet is surrounded by the cyclone separator. The primary combustion chamber may further include an ash transfer ram movably disposed between two stepped hearths, wherein the ash transfer ram includes a top layer of refractory material extending rearwardly from a leading edge thereof. The ash transfer ram may further include a plurality of V-shaped wheels attached to a bottom surface thereof, a replaceable wear plate disposed on a side surface thereof and/or a wiper blade fixed on a forward face thereof.

Abstract: An inclined hearth combustor which generally includes a primary combustion chamber having a plurality of stepped hearths, a secondary combustion chamber in communication with the primary combustion chamber and a boiler having an inlet in communication with the secondary combustion chamber. The secondary combustion chamber includes a refractory-lined cyclone separator for removing fly ash from combustion gases exiting the primary combustion chamber and the boiler inlet is surrounded by the cyclone separator. The primary combustion chamber may further include an ash transfer ram movably disposed between two stepped hearths, wherein the ash transfer ram includes a top layer of refractory material extending rearwardly from a leading edge thereof. The ash transfer ram may further include a plurality of V-shaped wheels attached to a bottom surface thereof, a replaceable wear plate disposed on a side surface thereof and/or a wiper blade fixed on a forward face thereof.

Abstract: An inclined hearth combustor which generally includes a primary combustion chamber having a plurality of stepped hearths, a secondary combustion chamber in communication with the primary combustion chamber and a boiler having an inlet in communication with the secondary combustion chamber. The secondary combustion chamber includes a refractory-lined cyclone separator for removing fly ash from combustion gases exiting the primary combustion chamber and the boiler inlet is surrounded by the cyclone separator. The primary combustion chamber may further include an ash transfer ram movably disposed between two stepped hearths, wherein the ash transfer ram includes a top layer of refractory material extending rearwardly from a leading edge thereof. The ash transfer ram may further include a plurality of V-shaped wheels attached to a bottom surface thereof, a replaceable wear plate disposed on a side surface thereof and/or a wiper blade fixed on a forward face thereof.

Abstract: A system and method for reducing or eliminating pump cavitation in a closed system having at least one or a plurality of fluid phase changes. The system comprises a venturi having a throat which is coupled to a reservoir tank.

Abstract: This invention relates to pyrrolocarbazole derivatives according formula I wherein R1, R2, R7, R8, R9, X and Y are as defined in the specification wherein said derivatives specifically inhibit one or both of the checkpoint kinases Wee1 and Chk1

Abstract: A system and method for reducing or eliminating pump cavitation in a closed system having at least one or a plurality of fluid phase changes. The system comprises a venturi having a throat which is coupled to a reservoir tank.

Abstract: This invention relates to modulating (e.g., inhibiting) protein tyrosine phosphatase 1B (PTP1B).

Abstract: According to one example of the invention an optical fiber comprises: (i) silica based, rare earth doped core having a first index of refraction n1; (ii) at least one silica based cladding surrounding the core and having a second index of refraction n2, such that n1>n2; wherein at least one of the core or cladding is doped with Al2O3, such that the ratio of max wt % to min wt % of Al2O3 concentration is less than 2:1

Abstract: An inclined hearth combustor which generally includes a primary combustion chamber having a plurality of stepped hearths, a secondary combustion chamber in communication with the primary combustion chamber and a boiler having an inlet in communication with the secondary combustion chamber. The secondary combustion chamber includes a refractory-lined cyclone separator for removing fly ash from combustion gases exiting the primary combustion chamber and the boiler inlet is surrounded by the cyclone separator. The primary combustion chamber may further include an ash transfer ram movably disposed between two stepped hearths, wherein the ash transfer ram includes a top layer of refractory material extending rearwardly from a leading edge thereof. The ash transfer ram may further include a plurality of V-shaped wheels attached to a bottom surface thereof, a replaceable wear plate disposed on a side surface thereof and/or a wiper blade fixed on a forward face thereof.

Abstract: The present invention provides an improved orthopedic system for the modification of the distance between the maxilla and zygoma. In a preferred embodiment, the system includes proximal and distal footplates attached to an orthopedic device. The distal footplate is attached to the zygoma, with the proximal footplate being mechanically coupled to the maxilla. This mechanical coupling is achieved either through attachment directly to the maxilla or by attachment to a construct which is then wired to the patient's teeth. The orthopedic device, which may be a distractor, allows for modification of the distance between the maxilla and zygoma. The entire system can advantageously be placed intra-orally within a patient. In a preferred embodiment, the footplates are also detachable from the orthopedic device and are composed of a bioresorbable material, such that they will be absorbed by the patient's body. Methods for using this novel orthopedic system are also disclosed.

Abstract: Protein tyrosine phosphatases (PTPases) such as PTP1B can play a role in regulating a wide variety of cellular responses such as insulin signaling. Substituted bicyclic fused-thiophene compounds can inhibit PTP1B and thereby induce greater insulin sensitivity. Accordingly, PTP1B inhibition can provide an alternate treatment for PTPase-mediated disorders such as diabetes.

Abstract: The present invention is broadly directed to methods of screening viral-binding compounds. In particular, the present invention provides cell-free assays to rapidly screen libraries of compounds for viral-capsid binding activity. Such compounds are useful for anti-viral treatments.

Abstract: Methods, systems, and media for managing dynamic memory are disclosed. Embodiments may disclose identifying nodes with having memory for dynamic storage, and reserving a portion of the memory from the identified nodes for a heap pool. After generating a heap pool, embodiments may allocate dynamic storage from the heap pool to tasks received that are associated with one of the identified nodes. More specifically, embodiments identify the node or home node associated with the task, the amount of dynamic storage requested by the task, and create a heap object in the node associated with the task to provide the requested dynamic storage. Some embodiments involve de-allocating the dynamic storage assigned to the task upon receipt of an indication that the task is complete and the dynamic storage is no longer needed for the task. Several of such embodiments return the de-allocated dynamic storage to the heap pool for reuse.

Abstract: An apparatus, program product and method in which application program-specified resource allocation and allocation strength preferences are used to allocate hardware resources from a computer for that application program. The resource allocation preference is used to allocate hardware resources for the application program, while the allocation strength preference is used to determine whether to allocate alternate hardware resources when the resource allocation preference specified by the application program cannot be met.

Abstract: A variable reluctance load cell for measuring the static or slowly fluctuating load, or tension, on devices is contained in a support tube. A sensor in the tube utilizes opposing C and I shaped magnetic cores attached to opposing ends of the support tube. A magnetic circuit is formed having an inductance defined by the size of the gap between the magnetic cores with the reluctance dominated by the gap. The sensor inductance is coupled with a fixed, predetermined capacitance in a resonant LC circuit, and the resonant frequency is a function of the gap. The sensor is in a cavity within the tube, and the cavity is sealed in a manner that prevents water or other damaging agents from entering the sensor. In this manner, mounting the sensor and tube to a static device and measuring the AC voltage at the sensor, the amount of load, or stress can be determined.

Abstract: An electrical connector assembly is provided for terminating a plurality of electrical wires. A non-conductive connector housing mounts a plurality of signal terminals. A wire management module includes a non-conductive body mounting a plurality of ground terminals. The body positions a plurality of signal conductors and a plurality of ground conductors of the electrical wires, the ground conductors being terminated to the ground terminals. The ground terminals interengage with the connector housing to mount the wire management module to the housing with the signal wire conductors in position for termination to the signal terminals.