Patents by Inventor Karel J. Lambert

Karel J. Lambert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of making encapsulated gas microspheres useful as an ultrasonic imaging agent
    Patent number: 5552133
    Abstract: Encapsulated gas microspheres useful as an ultrasonic imaging agent are made by: mixing an aqueous solution of a heat-denaturable protein with a gas, and passing the gas-solution mixture through a mill whereby the mixture is emulsified near the denaturation temperature of the protein and subjected to mechanical shearing and cavitation which causes the formation of gas bubbles in the 0.1 to 10 micron range, and the protein to locally denature and deposit at the gas-liquid interface to form the encapsulated microspheres.
    Type: Grant
    Filed: August 12, 1994
    Date of Patent: September 3, 1996
    Assignee: Molecular Biosystems, Inc.
    Inventors: Karel J. Lambert, Edward G. Jablonski, Carl Hulle