Abstract: A lancing device comprises a lancet drive to cause a lancet to effect a puncturing movement, a housing that encloses the lancet drive, and a touching element with an opening for applying a part of a body in which a prick wound is to be produced, the touching element being movable relative to the lancet drive for the purpose of adjusting the puncturing depth in a puncturing direction. The touching element is connected rotatably by means of a screw thread to an intermediate piece and is movable in the puncturing direction, while the intermediate piece is rotatable and movable relative to the housing. A guide prevents rotation of the touching element relative to the housing, and the touching element is enclosed by the intermediate piece at least over part of its length.

Abstract: The invention concerns a method to detect and evaluate movement patterns and pen positions of an electronic pen with inertial measurement sensors during writing on a two-dimensional writing substrate, comprising: •an initial specification of two axes X, Y, that are orthogonal to each other on the writing substrate, and an axis Z that is perpendicular to the two-dimensional writing substrate, •whereby the X-axis defines the predominant writing direction, as well as a compensation of undesired drift in the pen position signal of the electronic pen to be output, comprising: •a moving average process during a predefined time interval and a predetermined frequency of the pen movements on the writing substrate, determined by the inertial measurement sensors during writing through integration of the sensor data of the measurement sensors, along the two said axes X, Y, that are orthogonal to each other, and a •periodic comparison of currently determined moving average values with initial average values and/or with pr

Abstract: The present invention relates to a method of recognizing and evaluating pen positions of an electronic pen with inertial measurement sensors during writing on a two-dimensional writing substrate, comprising: initially specifying a writing coordinate system with two axes X, Y (101, 102, 201, 202), which are orthogonal to each other, on the writing substrate (108, 205) and an axis Z (103) perpendicular to the two-dimensional writing substrate (108, 205), the X axis (101, 201) defining e.g. the predominant writing direction, and the writing substrate coordinates x, y being defined with respect to said writing coordinate system, and compensating an undesirable drift in the pen position signal of the electronic pen to be output, comprising executing in parallel a coordinate transformation of the azimuthal angle s (105, 203) and of the inclination angle y (104) of the electronic pen (100, 200, 300) into writing substrate coordinates x, y.

Abstract: The present invention relates to a novel molecule comprising three binding sites with specificity for a tumor cell, for an effector cell and for a checkpoint molecule, respectively. Moreover, the present invention relates to a pharmaceutical composition comprising such a molecule and to uses of such a molecule.

Abstract: The invention relates to an evaporator comprising an evaporator body (3) surrounded by an evaporator housing (5), wherein the evaporator housing (5) is provided with a feed line (1) for feeding a liquid into the evaporator housing (5) and with an outlet (6) for emitting any vapour produced, wherein the evaporator body (3) comprises a multiplicity of plates (7) which are arranged in a planar manner one above another, wherein a void (8) is formed in each case between adjacent plates (7), wherein each of the voids (8) is fluidically connected to the outlet, wherein a liquid distributor is interconnected between the feed line (1) and the evaporator body (3), wherein the liquid distributor branches off from the feed line (1) in the direction of the evaporator body (3) in at least two distributor lines (VR), and wherein each distributor line (VR) is connected to at least one void (8).

Abstract: A system includes a capacitance sensor having an inertial proof mass disposed between a first electrode structure and a second electrode structure. A switching system is switchable between providing one of a positive charge pulse and a negative charge pulse to one of the first electrode structure and the second electrode structure. A controller controls the switching of the switching circuit to provide one of the positive charge pulse or the negative charge pulse to the first electrode structure during a first portion of a charge cycle time period and to provide an opposite polarity charge pulse from that provided to the first electrode structure to the second electrode structure during a second portion of the charge cycle time period to generate an error signal with respect to the inertial proof mass of the capacitance sensor.

Abstract: A laser device includes a light source that emits a source light having a first peak wavelength. A nonlinear optical component performs a frequency conversion process that converts the source light into output light having a second peak wavelength. A stabilization component minimizes a mismatch error constituting a difference between the first peak wavelength and a wavelength for which the frequency conversion process in the nonlinear optical component has a maximum value. The stabilization component may include a housing that is thermally conductive between the light source and the nonlinear optical component to minimize a temperature difference between the light source and the nonlinear optical component. The laser device may include a focusing optical component that focuses the source light to have a convergence half angle that is larger than a convergence half angle that gives maximum output power, thereby increasing an acceptable range of the mismatch error.

Abstract: A wavelength separating element is provided for separating a converted beam from a fundamental beam in an NLFC device, wherein the converted beam has a wavelength different from a wavelength of the fundamental beam. The wavelength separating element includes a first mirror surface and a second mirror surface opposite to the first mirror surface. The first and second mirror surfaces may have a high reflectivity of the converted beam relative to a reflectivity of the fundamental beam, and the first and second mirror surfaces are configured such that the fundamental and converted beams undergo multiple reflections between the first mirror surface and the second mirror surface to separate the converted beam from the fundamental beam. The fundamental and converted beams undergo at least three reflections at the first and second mirror surfaces, and/or undergo at least two reflections at one of the first mirror surface or the second mirror surface.

Abstract: A technique is provided for synchronizing a first call state of a network component and a second call state of a mobile device. The mobile device is connectable to a network via a first Radio Access Technology (RAT) and a second RAT. The network forwards towards a callee an invitation for a call originating via the first RAT from the mobile device. The network sends a first message corresponding to a callee response towards the mobile device. The network component triggers a transfer of the call session of the mobile device from the first RAT to the second RAT. The first call state is set by the response of the callee. Information indicative of the second call state is received from the mobile device, and a second message for changing the second call state by the response is provided to the mobile device when inconsistent first and second call states.

Abstract: Raw data is received that characterizes each of a plurality of transactions. The data can be received, for example, via an adapter coupled to at least one data source. At least one first table is populated using the raw data according to a normalized data model. At least one second table is then populated, by applying a key figure data model to transform and enrich the at least one first table, such that it is optimized for data analysis operations. The at least one second table can include a subset of data stored in the at least one first table and additional enrichment data. At least one data analysis operation can later be initiated on the data populated in at least one second table to characterize one or more aspects of the transactions. Data can be provided that characterizes the initiated at least one data operation.

Abstract: A laser device includes a light source that emits a source light having a first peak wavelength. A nonlinear optical component performs a frequency conversion process that converts the source light into output light having a second peak wavelength. A stabilization component minimizes a mismatch error constituting a difference between the first peak wavelength and a wavelength for which the frequency conversion process in the nonlinear optical component has a maximum value. The stabilization component may include a housing that is thermally conductive between the light source and the nonlinear optical component to minimize a temperature difference between the light source and the nonlinear optical component. The laser device may include a focusing optical component that focuses the source light to have a convergence half angle that is larger than a convergence half angle that gives maximum output power, thereby increasing an acceptable range of the mismatch error.

Abstract: The invention relates to an electronic stylus for performing inputs to a digital input device with an electrically capacitively acting touch-sensitive input surface, wherein the electronic stylus is configured for assuming at least two states (101, 102) with different electrical capacitances (114, 113) and for switching alternately between said different states (101, 102) with different electrical capacitances (114, 113), characterised in that the electronic stylus is configured for carrying out the switching (112) between states (101, 102) of the electronic stylus with different electric capacitances (114, 113) such that the state duration (116) for a first state (101) with a first electrical capacitance (114) is longer than the state duration (117) for a second state (102) with a second electrical capacitance (113).

Abstract: Techniques and apparatus are described for controlling set up of a terminating call from an IMS to a UE, in a Circuit Switched Fallback (CSFB) situation. A first MSC receives a terminating call from IMS and tries to page the UE. The UE has moved to the second MSC and performs a Location Update to the second MSC. The second MSC informs the first MSC with a Send Identification message comprising an address of the second MSC. The first MSC maintains the IMS subscription of the UE at Cancel Location and forwards the terminating call to the second MSC. The first MSC acts as relay for subsequent call control messages for calls of the UE. The first and second MSCs are supervising the ongoing calls and as soon as all calls are completed the second MSC registers the UE into IMS and the first MSC de-registers the UE from IMS.

Abstract: There is provided a process for preparing a zirconium-based metal organic framework (Zr-MOF), the process comprising the steps (i) preparing a reaction mixture comprising zirconium ions, sulfate ions and at least one organic linker compound in an aqueous solvent; and (ii) heating the reaction mixture from step (i).

Abstract: A technique for handling mobile terminating connection attempts for a mobile terminal for which a change of an association from a first routing node to a second routing node is accompanied by a Circuit Switched (CS) fallback is described. In one exemplary embodiment, a method may be performed by a Circuit Switched Fallback Interworking Function (CSFB-IWF) for handling mobile terminating connection attempts for a mobile terminal for which a change of an association from the CSFB-IWF to a Mobile Switching Center (MSC) is accompanied by a Circuit Switched Fallback (CSFB). The method may include receiving a mobile terminating connection attempt to the mobile terminal. In response to receiving the mobile terminating connection attempt, the method may include paging the mobile terminal using a Mobility Management Entity (MME). In response to paging the mobile terminal, the method may include triggering the mobile terminal to initiate a CSFB procedure.

Abstract: The present invention relates to the (S)-enantiomer of mepazine, its applicability in therapy, a pharmacological composition comprising (S)-mepazine, and processes for the preparation of (S)-mepazine and one of its intermediates.

Abstract: A technique for triggering a change of a call state of a mobile device is presented. A network forwards towards a callee an invitation for a call originating via a first Radio Access Technology (RAT) from the mobile device, and forwards a response of the callee via the first RAT towards the mobile device. The response indicates a change of the call state from a first state to a second state. A first network component changes via a second RAT the call state of the mobile device when receiving information indicative of the first state followed by receiving a message indicative of the second state. A second network component receives from the first network component an invitation for a transfer of the call of mobile device from the first RAT to the second RAT.

Abstract: A laser device includes a light source that emits a source light having a first peak wavelength. A nonlinear optical component performs a frequency conversion process that converts the source light into output light having a second peak wavelength. A stabilization component minimizes a mismatch error constituting a difference between the first peak wavelength and a wavelength for which the frequency conversion process in the nonlinear optical component has a maximum value. The stabilization component may include a housing that is thermally conductive between the light source and the nonlinear optical component to minimize a temperature difference between the light source and the nonlinear optical component. The laser device may include a focusing optical component that focuses the source light to have a convergence half angle that is larger than a convergence half angle that gives maximum output power, thereby increasing an acceptable range of the mismatch error.

Abstract: A wavelength separating element is provided for separating a converted beam from a fundamental beam in an NLFC device, wherein the converted beam has a wavelength different from a wavelength of the fundamental beam. The wavelength separating element includes a first mirror surface and a second mirror surface opposite to the first mirror surface. The first and second mirror surfaces may have a high reflectivity of the converted beam relative to a reflectivity of the fundamental beam, and the first and second mirror surfaces are configured such that the fundamental and converted beams undergo multiple reflections between the first mirror surface and the second mirror surface to separate the converted beam from the fundamental beam. The fundamental and converted beams undergo at least three reflections at the first and second mirror surfaces, and/or undergo at least two reflections at one of the first mirror surface or the second mirror surface.

Abstract: There is disclosed an insertion device comprising an insertion needle holder and a drive mechanism for linearly moving the insertion needle holder in a puncturing direction. The insertion needle holder also includes at least one actuating element for actuating a drive mechanism. The drive mechanism converts a driving motion of the actuating element, which extends transversely or opposite to the puncturing direction, into a puncturing motion of the insertion needle holder.