Abstract: The object is to provide a lysis method, lysis treatment solution, detection method using an immunochromatographic device, and detection kit comprising an immunochromatographic device for detecting whether causative bacterium of mastitis is a staphylococcus or not by using milk of a livestock animal. There is provided a method for lysing a staphylococcus, which comprises the step of mixing a lysis agent containing a lytic enzyme, and at least one kind of ampholytic surfactant, and preferably further containing at least one kind of nonionic surfactant, with milk obtained form a livestock animal to lyse a staphylococcus existing in the milk. The lytic enzyme is preferably lysostaphin.

Abstract: The object is to provide a lysis method and lysis treatment solution for efficiently lysing cells of various Streptococcus bacteria in milk of a livestock animal to release a specific antigen substance contained in the cells for detecting whether causative bacterium of mastitis is a Streptococcus bacterium or not by using the milk, as well as a detection method using an immunochromatographic device. There is provided a method for lysing a Streptococcus bacterium, which comprises the step of mixing a lysis agent containing a lytic enzyme with milk obtained form a livestock animal to lyse a Streptococcus bacterium existing in the milk. The lytic enzyme is preferably at least one selected from the group consisting of lysozyme, labiase, and ?-N-acetylglucosaminidase.

Abstract: A liquid storing container includes a case, a flexible member, a pressure receiving member, a first urging member, and a second urging member. The case constitutes a part of an inner wall of a liquid containing section configured to store liquid. The flexible member constitutes at least a part of a remaining inner wall of the liquid containing section. The pressure receiving member is arranged between the case and the flexible member. The first urging member is provided between the pressure receiving member and the case, and one end is connected to the pressure receiving member to urge the pressure receiving member from the case to the flexible member. The second urging member is provided between the pressure receiving member and the case, and one end is connected to the pressure receiving member to urge the pressure receiving member from the case to the flexible member.

Abstract: An immunochromatographic method for detecting a specific substance contained in milk, which comprises (1) the step of contacting the milk with a test strip having a first part retaining a labeled first antibody directed to the specific substance or the specific substance that is labeled, a second part disposed downstream from the first part, on which a second antibody directed to the specific substance is immobilized, and a third part disposed upstream from the first part or the second part and having voids enabling removal of milk fat globules contained in the milk, at the third part or a further upstream part, and (2) the step of flowing the milk up to the second part or a further downstream part to obtain a detectable signal of the label at the second part or a further downstream part.

Abstract: A liquid storing container includes a case, a flexible member, a pressure receiving member, a first urging member, and a second urging member. The case constitutes a part of an inner wall of a liquid containing section configured to store liquid. The flexible member constitutes at least a part of a remaining inner wall of the liquid containing section. The pressure receiving member is arranged between the case and the flexible member. The first urging member is provided between the pressure receiving member and the case, and one end is connected to the pressure receiving member to urge the pressure receiving member from the case to the flexible member. The second urging member is provided between the pressure receiving member and the case, and one end is connected to the pressure receiving member to urge the pressure receiving member from the case to the flexible member.

Abstract: A print device including a transport roller for transporting a recording medium in which a pair of end surfaces of a metallic plate faces each other so as to be molded in a cylindrical shape, wherein at least one end surface of the pair of end surfaces includes a first portion which comes into plane contact with the other end surface of the pair of end surfaces at an outer periphery surface side of the transport roller, and a second portion which has a gap between the second portion and the other end surface at an inner periphery surface side thereof.

Abstract: A heat exchanger includes a corrugated plate that has a corrugation; a fluid-flux portion that stores the corrugated plate, and makes a fluid flow; a first structure that constitutes the fluid-flux portion; and a second structure that constitutes the fluid-flux portion, and is provided on a heat source side with respect to the first structure, wherein at least a portion constituting the fluid-flux portion in the second structure has a flat plate shape. The flat plate shape of the portion constituting the fluid-flux portion in the second structure enables easy manufacturing of the heat exchanger. The flat plate shape in the second structure further enables a close contact of the fluid-flux portion to the heat source, resulting in a heat exchange with high efficiency.

Abstract: An antibody for detection of microorganisms, a method of detection of microorganisms, and a reagent kit for detection of microorganisms, which is species specific for every species of microorganisms and with which all serototypes within the same species can be detected, are provided. Antibody to intracellular molecules with the same function in each type of microorganism, particular antibody to ribosomal protein, that is, ribosomal protein L7/L12, is made and antibody that reacts specifically with the microorganism in question is selected.

Abstract: [Object] To provide a method for manufacturing a scale having an improved abrasion resistance, the scale, and an encoder having the same. [Solving Means] A scale base material 17 is arranged on the upper surface of a mount 26. A pattern base material 18? as a material of pattern portions 18 are laminated on the upper surface of the scale base material 17. In this laminated state, the pattern base material 18? is punched toward the scale base material 17 via a press work. Accordingly, the punched pattern base material 18? is embedded and held in a thickness of the scale base material 17, and the pattern portions 18 are formed.

Abstract: A metal plate member used as a filter for a liquid ejecting head or the like is a metal plate member with a plurality of through bores perforated therethrough, and on the surface thereof, pressure imprints by pressing a pressing member are formed.

Abstract: A spring member made by a simplified working process in which mistakes in assembling work are prevented, a liquid cartridge using the spring member, and a recording apparatus with the liquid cartridge are provided. A particular member of a spring member 1 is configured as a cap body 3 having an opening toward an elastic member and a sealing surface 3a at an end. An edge portion the opening is integrated with the elastic member 2. The cap body 3 includes a protruding piece 39 that protrudes from the edge portion of the opening of the cap body 3 toward the elastic member 2.

Abstract: A novel method of detecting and measuring the presence or amount of an analyte in a sample with high sensitivity and good simplicity is provided. A method of detecting an analyte, which comprises binding the analyte to a labeled specific binding substance to form a conjugate and detecting a magnetic signal from the conjugate to detect the analyte, wherein the labeled specific binding material comprises a substance capable of specifically binding to the analyte, a spacer and particular magnetic beads, and wherein the specific binding substance is coupled to the magnetic beads via the spacer.

Abstract: A heat exchanger includes a corrugated plate that has a corrugation; a fluid-flux portion that stores the corrugated plate, and makes a fluid flow; a first structure that constitutes the fluid-flux portion; and a second structure that constitutes the fluid-flux portion, and is provided on a heat source side with respect to the first structure, wherein at least a portion constituting the fluid-flux portion in the second structure has a flat plate shape. The flat plate shape of the portion constituting the fluid-flux portion in the second structure enables easy manufacturing of the heat exchanger. The flat plate shape in the second structure further enables a close contact of the fluid-flux portion to the heat source, resulting in a heat exchange with high efficiency.

Abstract: An antibody for detection of microorganisms, a method of detection of microorganisms, and a reagent kit for detection of microorganisms, which is species specific for every species of microorganisms and with which all serototypes within the same species can be detected, are provided. Antibody to intracellular molecules with the same function in each type of microorganism, particular antibody to ribosomal protein, that is, ribosomal protein L7/Ll2, is made and antibody that reacts specifically with the microorganism in question is selected.

Abstract: An N-acylamino acid derivative of the formula: ##STR1##

Abstract: An N-acylamino acid derivative of the formula: ##STR1## wherein each of R.sup.1, R.sup.2, R.sup.4 and R.sup.6 is hydrogen lower alkyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl or a monocyclic or bicyclic heterocyclic group containing from to 4 hetero atoms; each of R.sup.3 and R.sup.5 is hydrogen or lower alkyl; A is --CH(OH)--(CH.sub.2).sub.q R.sup.7 wherein R.sup.7 is hydrogen, lower alkyl, cycloalkyl, cyloalkylalkyl, aryl, aralkyl, a monocyclic or bicyclic heterocyclic group containing from to 4 hereto atoms or --E--R.sup.10 wherein E is --S(O).sub.i -- wherein i is 0, 1 or 2, oxygen, --NR.sup.11 -- wherein R.sup.11 is hydrogen, lower alkyl, cycloalkyl, cycloalkylalkyl, aryl or aralkyl, or ##STR2## wherein each of R.sup.12 and R.sup.13 is hydrogen, lower alkyl cycloalkyl, cycloalkylalkyl, aryl or aralkyl, and R.sup.10 is hydrogen, lower alkyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl or a monocyclic or bicyclic heterocyclic group containing from 1 to 4 hetero atoms provided that when R.sup.

Abstract: A DNA is disclosed, which comprises a gene coding for deacetylcephalosporin C acetyltransferase, i.e., an enzyme capable of catalyzing the final step of the biosynthesis of cephalosporin C. The gene may be either a cDNA or a genomic DNA. Also disclosed is a recombinant DNA comprising a vector having inserted therein at least a portion of the above-mentioned DNA, which recombinant DNA is in a form such that the portion is capable of expression in Acremonium chrysogenum. Acremonium chrysogenum transformed with the recombinant DNA can be advantageously used for efficiently preparing cephalosporin C.

Abstract: The present invention provides an N-substituted acylamino acid compound of the formula: ##STR1## a process for their production and pharmaceutical uses, and intermediates useful for their production.

Abstract: There are provided novel aminophosphonic acid derivatives of the general formula [I]: ##STR1## wherein n is an integer of 2 or 3; R.sup.1 is a phenyl, naphthyl, indolyl, benzothienyl, benzofuryl or benzoxazolyl group which may have 1 to 3 substituents selected from the group consisting of hydroxyl and lower alkyloxy groups, or a hydrogen atom; R.sup.2 is a lower alkyl group, a benzyl group, a 4-hydroxybenzyl group, a 3-indolylmethyl group or a .beta.-phenethyl group; and A is an optional residue of an amino acid selected from the group consisting of tryptophane, tyrosine, phenylalanine, homophenylalanine, naphthylalanine or N.sup..omega. -nitroarginine, and their pharmaceutically acceptable salts. The compounds according to the present invention and their pharmaceutically acceptable salts exhibit an inhibitory activity against endothelin-converting enzyme, and are expected to be useful as a drug treating various diseases with which endothelin is concerned.

Abstract: An N-acylamino acid derivative of the formula: ##STR1## wherein each of R.sup.1, R.sup.2, R.sup.4 and R.sup.6 is hydrogen, lower alkyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl or a monocyclic or bicyclic heterocyclic group containing from 1 to 4 hetero atoms; each of R.sup.3 and R.sup.5 is hydrogen or lower alkyl; A is --CH(OH)--(CH.sub.2).sub.q R.sup.7 wherein R.sup.7 is hydrogen, lower alkyl, cycloalkyl, cyloalkylalkyl, aryl, aralkyl, a-monocyclic or bicyclic heterocyclic group containing from 1 to 4 hetero atoms or --E--R.sup.10 wherein E is --S(O).sub.i -- wherein i is 0, 1 or 2, oxygen, --NR.sup.11 -- wherein R.sup.11 is hydrogen, lower alkyl, cycloalkyl, cycloalkylalkyl, aryl or aralkyl, or ##STR2## wherein each of R.sup.12 and R.sup.13 is hydrogen, lower alkyl, cycloalkyl, cycloalkylalkyl, aryl or aralkyl, and R.sup.10 is hydrogen, lower alkyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl or a monocyclic or bicyclic heterocyclic group containing from 1 to 4 hetero atoms provided that when R.sup.