Patents by Inventor Kenji Matsuyama

Kenji Matsuyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-acylamino acid derivatives and their use
    Patent number: 5240924
    Abstract: An N-acylamino acid derivative of the formula: ##STR1## wherein the substituents are herein defined, or a salt thereof, which is useful as hypotensive drugs.
    Type: Grant
    Filed: December 31, 1991
    Date of Patent: August 31, 1993
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Hajime Morishima, Yutaka Koike, Masato Nakano, Shugo Atsuumi, Seiichi Tanaka, Kenji Matsuyama
  • N-acylamino acid derivatives and their pharmaceutical compositions
    Patent number: 5122523
    Abstract: An N-acylamino acid derivative of the formula: ##STR1## wherein the substituents are herein defined or a salt thereof, which is useful as hypotensive drugs.
    Type: Grant
    Filed: September 6, 1988
    Date of Patent: June 16, 1992
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Hajime Morishima, Yutaka Koike, Masato Nakano, Shugo Atsuumi, Seiichi Tanaka, Kenji Matsuyama
  • 5-substituted amino-4-hydroxy-pentenoic acid derivatives and their use
    Patent number: 4927565
    Abstract: A 5-substituted amino-4-hydroxy-pentenoic acid or its salt represented by the formula: ##STR1## wherein each of R.sup.1 and R.sup.2 which may be the same or different is a hydrogen atom, a lower alkyl group, an aralkyl group, a lower alkoxycarbonyl group, an aryloxycarbonyl group, an aralkyloxycarbonyl group or a lower alkanoyl group which may be substituted by from one to three substituents selected from the group consisting of an amino group, a hydroxyl group, a carboxyl group, an aryloxy group, an aralkyloxycarbonylamino group, a lower alkoxycarbonylamino group and a ##STR2## group (wherein each of X.sup.1 and X.sup.2 which may be the same or different is a hydrogen atom, a lower alkyl group, an aryl group or an aralkyl group, or X.sup.1 and X.sup.
    Type: Grant
    Filed: December 16, 1987
    Date of Patent: May 22, 1990
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Seiichi Tanaka, Yutaka Koike, Masato Nakano, Shugo Atsuumi, Hajime Morishima, Kenji Matsuyama
  • 5-substituted amino-4-hydroxy-pentanoic acid derivatives and their use
    Patent number: 4851387
    Abstract: A 5-substituted amino-4-hydroxy-pentanoic acid derivative having the formula: ##STR1## wherein R.sup.1 is a hydrogen atom or an N-protecting group, R.sup.2, R.sup.3 and R.sup.5 may be any of a variety of groups including the side chains of amino acid residues, R.sup.4 is a hydrogen atom or a lower alkyl group, R.sup.6 is a group which is substituted by one or two hydroxyl groups, and R.sup.7 is any of a variety of groups, including a hydroxyl group, which compounds are renin inhibitors useful as hypotensive drugs, are disclosed.
    Type: Grant
    Filed: October 13, 1987
    Date of Patent: July 25, 1989
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Yutaka Koike, Masato Nakano, Shugo Atsuumi, Seiichi Tanaka, Hajime Morishima, Kenji Matsuyama
  • Process for preparing a 7-aminocephalosporanic acid compound
    Patent number: 4774179
    Abstract: A process for preparing a 7-aminocephalosporanic acid compound which comprises treating a cephalosporin C compound with an enzyme-producing microorganism belonging to the genus Pseudomonas or a material obtained by subjecting the microorganism to chemical and/or physical treatment. A direct hydrolysis of the cephalosporin C compound into the 7-aminocephalosporanic acid compound and D-.alpha.-aminoadipic acid can be attained by the microorganism or material.
    Type: Grant
    Filed: July 9, 1985
    Date of Patent: September 27, 1988
    Assignee: Asahi Kasei Kogyo Kabushiki Kaisha
    Inventors: Shigeaki Ichikawa, Keizou Yamamoto, Kenji Matsuyama
  • Indole derivatives having gastric and antisecretory and cytoprotective properties, and pharmaceutical preparations containing same
    Patent number: 4743609
    Abstract: This invention provides a class of new indole derivatives which are useful as medicinal compounds having a mild inhibitory effect on the gastric acid secretion as well as a remarkably cytoprotective effects on gastric muscosa, and which are represented by the general formula: ##STR1##
    Type: Grant
    Filed: February 10, 1986
    Date of Patent: May 10, 1988
    Assignee: Banyu Pharmaceutical Co., Ltd.
    Inventors: Masaaki Hosoi, Fumio Nakano, Kenji Matsuyama, Hiroshi Takeshita, Kenji Niiyama, Susumu Nakagawa