Abstract: The present disclosure is directed to examples of a light emitting diode (LED) device. In one embodiment, the LED device includes a printed circuit board (PCB), at least one LED chip electrically coupled to the PCB, a LED package to encapsulate the at least one LED chip, and at least one volatile organic compound (VOC) barrier layer coating the LED package.

Abstract: A method of manufacturing a backed cross-ply prepreg comprises cutting, using a cutting machine, a first continuous length of a unidirectional prepreg into first prepreg segments, each having an opposing pair of segment cut edges that are non-parallel to a lengthwise direction of the unidirectional prepreg. The method also includes picking up, using a pick-and-place system, the first prepreg segments off of the cutting machine, and placing the first prepreg segments in end-to-end relation onto a conveyor belt of an adhesion machine, and in an orientation such that the segment cut edges are generally parallel to a lengthwise direction of the conveyor belt. The method also includes feeding, using the conveyor belt, the first prepreg segments to an adhesion station of the adhesion machine, and adhering, using the adhesion station, the first prepreg segments to a continuous length of a backing material.

Abstract: A technique for monitoring valve and pump efficiencies for positive displacement pumps. The techniques include utilizing a data acquisition system to attain intake and discharge pressure data in combination with real-time encoder position data. Thus, when combined, output from a pump may be monitored in real-time. As a result, pump life may be extended beyond an anticipated changeout schedule. By the same token, premature pump inefficiencies may also be detected for taking a pump offline in advance of expected life. In either circumstance, multi-pump operations may be substantially enhanced with cost and time savings realized.

Abstract: A manufacturing system includes a cutting machine, an adhesion machine, and a pick-and-place system. The cutting machine sequentially cuts a continuous length of a unidirectional prepreg into prepreg segments. Each prepreg segment has an opposing pair of segment cut edges that are non-parallel to a lengthwise direction of the unidirectional prepreg. The adhesion machine has a conveyor belt and an adhesion station. The pick-and-place system sequentially picks up the prepreg segments from the cutting machine, and places the prepreg segments in end-to-end relation on the conveyor belt, and in an orientation such that the segment cut edges are generally parallel to a lengthwise direction of the conveyor belt. The conveyor belt feeds the prepreg segments to the adhesion station. The adhesion station adheres the prepreg segments to a continuous length of a backing material, thereby resulting in a continuous length of a backed cross-ply prepreg.

Abstract: The invention relates to compounds of Formula (I), a polymorph, an enantiomer, a stereoisomer, a solvate, an N-oxide derivative, or a pharmaceutically acceptable salt thereof: Formula (I), which have inhibitory effect on one or more protein kinases that are involved in cell mitosis.

Abstract: The invention relates to compounds of Formula (I), a polymorph, an enantiomer, a stereoisomer, a solvate, an N-oxide derivative, or a pharmaceutically acceptable salt thereof: Formula (I), which have inhibitory effect on one or more protein kinases that are involved in cell mitosis.

Abstract: The invention relates to compounds of Formula (I), a prodrug, a polymorph, a tautomer, an enantiomer, a stereoisomer, a solvate, an N-oxide, or a pharmaceutically acceptable salt thereof: (formula should be inserted here) which have inhibitory effect on one or more protein kinases that are involved in cell mitosis.

Abstract: Efficient fuel combustion catalyst delivery device and method are provided. A fuel combustion catalyst delivery device includes a storage vessel that contains a liquid. The liquid includes one or more catalytic materials. The storage vessel is attached to a nebulizer that can convert the liquid to an aerosol to be delivered into an air intake of a combustion zone. The aerosol can accelerate fuel combustion. The storage vessel and the nebulizer are made from materials suitable to be exposed to the liquid and the aerosol. The storage vessel and the nebulizer are also suitable to be placed in proximity to the combustion zone such as an engine compartment so that the aerosol can be delivered into the air intake of the combustion zone easily and effectively. The surfaces of the delivery device exposed to the liquid or the aerosol may be made of corrosion-resistant or inert materials if the liquid is acidic.

Abstract: Novel purine compounds and tautomers and pharmaceutically acceptable salts thereof are described, as are pharmaceutical compositions comprising the same, complexes comprising the same, e.g., HSP90 complexes, and methods of using the same.

Abstract: A system and method for custom branding a host application executed on a host device. The host device couples with an accessory device, where a host application is provided for managing/controlling the accessory device. During run time, i.e., when the accessory device is coupled with the host device, the host device can retrieve at least one resource object in which graphical user interface elements associated with the accessory device type have been encoded or preconfigured. The host device can then render the host application with the graphical user interface elements, effectively custom branding the host application.

Abstract: 2-Aminopurine analogs are described and demonstrated or predicted to have utility as Heat Shock Protein 90 (HSP90) inhibiting agents in the treatment and prevention of various HSP90 mediated disorders, e.g., proliferative disorders. Method of synthesis and use of such compounds are also described and claimed.

Abstract: Pyrrolopyrimidines and related analogs are described and demonstrated to have utility as Heat Shock Protein 90 (HSP90) inhibiting agents used in the treatment and prevention of various HSP90 mediated disorders, e.g., proliferative disorders. Methods of synthesis and use of such compounds are also described and claimed.

Abstract: Novel purine compounds of Formula I. and tautomers, pharmaceutically acceptable salts, and prodrugs thereof, wherein X is S, S(O), or S(O)2; and O is selected from alkyl, cycloalkyl, arylalkyl, aryl, heteroaryl, and heterocyclic, all optionally substituted, are described, as are pharmaceutical compositions comprising the same, complexes comprising the same, e.g., HSP90 complexes, and methods of using the same.

Abstract: Novel purine compounds and tautomers and pharmaceutically acceptable salts thereof are described, as are pharmaceutical compositions comprising the same, complexes comprising the same, e.g., HSP90 complexes, and methods of using the same. Methods of using the novel purine compounds of the invention, and tautomers and pharmaceutically acceptable salts thereof, include their use in inhibiting heat shock protein 90's (HSP90's) to thereby treat or prevent HSP90-dependent diseases, e.g., proliferative disorders such as breast cancer.

Abstract: Pyrazolopyrimidines and related analogs are described and demonstrated or predicted to have utility as Heat Shock Protein 90 (HSP90) inhibiting agents in the treatment and prevention of various HSP90 mediated disorders, e.g., proliferative disorders. Method of synthesis and use of such compounds are also described and claimed.

Abstract: Triazolopyrimidines and related compounds are described and demonstrated or predicted to have utility as Heat Shock Protein 90 (HSP90) inhibiting agents in the treatment and prevention of various HSP90 mediated disorders, e.g., proliferative disorders. Method of synthesis and use of such compounds are also described and claimed.

Abstract: Efficient fuel combustion catalyst delivery device and method are provided. A fuel combustion catalyst delivery device includes a storage vessel that contains a liquid. The liquid includes one or more catalytic materials. The storage vessel is attached to a nebulizer that can convert the liquid to an aerosol to be delivered into an air intake of a combustion zone. The aerosol can accelerate fuel combustion. The storage vessel and the nebulizer are made from materials suitable to be exposed to the liquid and the aerosol. The storage vessel and the nebulizer are also suitable to be placed in proximity to the combustion zone such as an engine compartment so that the aerosol can be delivered into the air intake of the combustion zone easily and effectively. The surfaces of the delivery device exposed to the liquid or the aerosol may be made of corrosion-resistant or inert materials if the liquid is acidic.

Abstract: Pyrazolopyrimidines and related analogs are described and demonstrated or predicted to have utility as Heat Shock Protein 90 (HSP90) inhibiting agents in the treatment and prevention of various HSP90 mediated disorders, e.g., proliferative disorders. Method of synthesis and use of such compounds are also described and claimed.

Abstract: 2-Aminopurine analogs are described and demonstrated or predicted to have utility as Heat Shock Protein 90 (HSP90) inhibiting agents in the treatment and prevention of various HSP90 mediated disorders, e.g., proliferative disorders. Method of synthesis and use of such compounds are also described and claimed.

Abstract: Triazolopyrimidines and related compounds are described and demonstrated or predicted to have utility as Heat Shock Protein 90 (HSP90) inhibiting agents in the treatment and prevention of various HSP90 mediated disorders, e.g., proliferative disorders. Method of synthesis and use of such compounds are also described and claimed.