Abstract: A battery pack is advantageous for effective control and maintenance of thermal events. A battery pack according to one aspect of the present disclosure may include a battery module having one or more battery cells; a fire extinguishing tank holding a fire extinguishing liquid, disposed on top of the battery module and having a through hole formed therein; and a cover member installed in the through hole of the fire extinguishing tank and configured to open or close the through hole according to a change in internal pressure of the fire extinguishing tank.

Abstract: Disclosed are a multilayered cell sheet of cardiac stem cells (CSCs) and a method of manufacturing the same. In particular, the present disclosure provides a method of manufacturing a multilayered cell sheet according to a single step culture procedure by using, as a three-dimensional matrix, a biodegradable natural polymer hydrogel and embedding CSCs in the hydrogel. The multilayered cell sheet of the present disclosure does not require any special device for the manufacturing, is manageable with good physicomechanical property, increases a cell engraftment rate after transplantation based on sufficient accumulation of various growth and protective factors and extracellular matrix between cells, and is also self-assembled by the cell-mediated hydrogel compaction, making nutrients transfer easy. Therefore, the multilayered cell sheet of the CSCs is expected to be usefully applicable as a therapeutic agent for myocardium regeneration.

Abstract: An axle assembly for drive wheels of vehicles includes a steering knuckle, an axle housing coupled to an inside of the steering knuckle, a wheel disc that is fixed to the axle housing to be rotatable integrally with the axle housing, and a drive shaft that is coupled to the axle housing to be rotatable integrally with the axle housing. A hub bearing is disposed between the steering knuckle and the axle housing. A forming part is formed at an end of the axle housing in a state in which a bearing inner race of the hub bearing is coupled to an outer circumferential surface of the axle housing, and the bearing inner race is engaged with a side part of the axle housing by the forming part in a state in which the forming part is pressed against a side end of the bearing inner race.

Abstract: Provided are an injectable intraocular microgel and an injectable intraocular hydrogel that are safe to a human body and that can release a drug in the eye for a long period of time. This injectable intraocular microgel may have a form in which a drug is loaded on a hyaluronic acid microgel generated by causing hyaluronic acid copolymers to cross-link with each other through a w/o emulsion method.

Abstract: A preparation method of calcium peroxide-mediated in situ crosslinkable hydrogel as a sustained oxygen-generating matrix, includes: a) reacting a natural or a synthetic polymer with Traut's reagent (TR) in a solvent, and synthesizing a polymer derivative having thiol group in backbone of the polymer derivative; and b) mixing and reacting a solution of the polymer derivative having thiol group with calcium peroxide (CaO2), and thereby forming a hydrogel, wherein in the step b), disulfide bonds (—S—S) are induced between backbones of the polymer derivative having thiol group attached by decomposition of calcium peroxide (CaO2), and thereby in situ crosslinking is formed.

Abstract: A preparation method of calcium peroxide-mediated in situ crosslinkable hydrogel as a sustained oxygen-generating matrix, includes: a) reacting a natural or a synthetic polymer with Traut's reagent (TR) in a solvent, and synthesizing a polymer derivative having thiol group in backbone of the polymer derivative; and b) mixing and reacting a solution of the polymer derivative having thiol group with calcium peroxide (CaO2), and thereby forming a hydrogel, wherein in the step b), disulfide bonds (—S—S) are induced between backbones of the polymer derivative having thiol group attached by decomposition of calcium peroxide (CaO2), and thereby in situ crosslinking is formed.

Abstract: A constant velocity joint assembly integrated with a wheel hub device may include an internal race coupled to an end portion of a driveshaft, a plurality of joint balls held in the internal race, and a hub housing accommodating and coupling the internal race holding the joint balls therein, with a bearing coupled to an external circumferential surface thereof, the hub housing provided as an external race of a constant velocity joint and the wheel hub device.

Abstract: Disclosed are a multilayered cell sheet of cardiac stem cells (CSCs) and a method of manufacturing the same. In particular, the present disclosure provides a method of manufacturing a multilayered cell sheet according to a single step culture procedure by using, as a three-dimensional matrix, a biodegradable natural polymer hydrogel and embedding CSCs in the hydrogel. The multilayered cell sheet of the present disclosure does not require any special device for the manufacturing, is manageable with good physicomechanical property, increases a cell engraftment rate after transplantation based on sufficient accumulation of various growth and protective factors and extracellular matrix between cells, and is also self-assembled by the cell-mediated hydrogel compaction, making nutrients transfer easy. Therefore, the multilayered cell sheet of the CSCs is expected to be usefully applicable as a therapeutic agent for myocardium regeneration.

Abstract: The present disclosure relates to a method for immobilizing heparin and a NO-generating catalyst and a cardiovascular device having a surface modified using the same, and more particularly, to a method of co-immobilizing a heparin-phenol derivative and copper nanoparticles as a NO-generating catalyst on the surface of a material by a polyphenol oxidase-mediated reaction, a material having a surface with heparin and a NO-generating catalyst co-immobilized thereon by using the method, and a cardiovascular device including the material. It has been confirmed that a surface having heparin and the NO-generating catalyst co-immobilized thereon by the method of the present disclosure has high in vivo stability, continuously generates NO, and also promotes the proliferation of endothelial cells while significantly inhibiting the adhesion and activation of platelets and smooth muscle cells. Thus, the method may be advantageously applied to cardiovascular devices for inhibiting thrombosis and restenosis.

Abstract: Provided are an injectable tissue adhesive hydrogel including gamma-cyclodextrin (?-CD). When such an injectable tissue adhesive hydrogel including the ?-CD is used as a skin glue, based on a fact that the ?-CD has a bigger hydrophobic cavity than that of ?- and ?-CDs, the injectable tissue adhesive hydrogel including the ?-CD has stronger interactions than host-guest interactions. In addition, hydrogen bonding in the injectable tissue adhesive hydrogel including the ?-CD can improve both cohesiveness and adhesiveness of gelatin. The injectable tissue adhesive hydrogel including the ?-CD having excellent cell viability is used for adhesion of a skin incision, to thereby effectively promote tissue regeneration.

Abstract: An axle assembly for drive wheels of vehicles includes a steering knuckle, an axle housing coupled to an inside of the steering knuckle, a wheel disc that is fixed to the axle housing to be rotatable integrally with the axle housing, and a drive shaft that is coupled to the axle housing to be rotatable integrally with the axle housing. A hub bearing is disposed between the steering knuckle and the axle housing. A forming part is formed at an end of the axle housing in a state in which a bearing inner race of the hub bearing is coupled to an outer circumferential surface of the axle housing, and the bearing inner race is engaged with a side part of the axle housing by the forming part in a state in which the forming part is pressed against a side end of the bearing inner race.

Abstract: A constant velocity joint assembly integrated with a wheel hub device may include an internal race coupled to an end portion of a driveshaft, a plurality of joint balls held in the internal race, and a hub housing accommodating and coupling the internal race holding the joint balls therein, with a bearing coupled to an external circumferential surface thereof, the hub housing provided as an external race of a constant velocity joint and the wheel hub device.

Abstract: Provided is a catheter to be inserted into an object. The catheter includes a main body having a tubular shape and an expansion layer formed on an outer circumferential surface of the main body, and the expansion layer contains an expandable material which is expanded by contact with a liquid.

Abstract: The present invention relates to a method for preparing a hydrogel, including the steps of: preparing an enzyme-immobilized support; making contacting with a polymer having a phenol or aniline functional group at a side change and the support in the presence of hydrogen peroxide to cross-link the same; and obtaining a hydrogel by separating the enzyme-immobilized support. According to the present invention, a hydrogel is formed by cross-linking a polymer having a phenol or aniline functional group at a side chain through an enzyme-immobilized support, and thus a hydrogel containing no enzymes is obtained. Therefore, the biomedical application range of a hydrogel can be expanded since it is possible to overcome an in vivo safety problem such as immune reaction caused by an enzyme.

Abstract: Provided are an injectable tissue adhesive hydrogel including gamma-cyclodextrin (?-CD). When such an injectable tissue adhesive hydrogel including the ?-CD is used as a skin glue, based on a fact that the ?-CD has a bigger hydrophobic cavity than that of ?- and ?-CDs, the injectable tissue adhesive hydrogel including the ?-CD has stronger interactions than host-guest interactions. In addition, hydrogen bonding in the injectable tissue adhesive hydrogel including the ?-CD can improve both cohesiveness and adhesiveness of gelatin. The injectable tissue adhesive hydrogel including the ?-CD having excellent cell viability is used for adhesion of a skin incision, to thereby effectively promote tissue regeneration.

Abstract: A disconnector for a hybrid vehicle, which can accurately control interruption or transmission of rotary power by accurately measuring and monitoring a transfer distance of a shift fork using a linear sensor while interrupting or transmitting the rotary power of an engine or a motor using the shift fork.

Abstract: Disclosed is a multi-layered structure for drug reservoir, comprising a first micelle layer for crosslinking and adhesion, comprising a drug, a multi-arm polymer, a phenol derivative, and a dopa derivative and having a one or two-layered structure; a second micelle layer for crosslinking, being stacked on the first micelle layer, comprising a drug, a multi-arm polymer, and a phenol derivative, and having a one or two-layered structure; and a physiologically active material layer, being stacked on the second micelle layer, comprising a physiologically active material, a water-soluble polymer, and a phenol derivative, and having a one or two-layered structure.

Abstract: The present invention relates to a method for preparing a hydrogel, comprising the steps of: preparing an enzyme-immobilized support; making contacting with a polymer having a phenol or aniline functional group at a side change and the support in the presence of hydrogen peroxide to cross-link the same; and obtaining a hydrogel by separating the enzyme-immobilized support. According to the present invention, a hydrogel is formed by cross-linking a polymer having a phenol or aniline functional group at a side chain through an enzyme-immobilized support, and thus a hydrogel containing no enzymes is obtained. Therefore, the biomedical application range of a hydrogel can be expanded since it is possible to overcome an in vivo safety problem such as immune reaction caused by an enzyme.

Abstract: Disclosed is a disconnector for a hybrid vehicle which can accurately control interruption or transmission of rotary power by accurately measuring and monitoring a transfer distance of a shift fork using a linear sensor while interrupting or transmitting the rotary power of an engine or a motor using the shift fork.

Abstract: Disclosed herein are an in situ-forming, bioadhesive hydrogel and the medical uses thereof. Being formed by in situ crosslinking through an enzymatic reaction, the hydrogel has an advantage over conventional bioadhesive hydrogels in terms of biocompatibility. In addition, the in situ-forming bioadhesive hydrogel has excellent biocompatibility and mechanical strength and has excellent tissue adhesiveness thanks to modification with/without dopa derivatives. The hydrogel finds a variety of applications in the biomedical field, including bioadhesives or hemostats, implant substances for tissue regeneration and augmentation, carriers for delivering biologically active materials or drugs, etc.