Patents by Inventor Kirk E. Apt

Kirk E. Apt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EICOSAPENTAENOIC ACID-PRODUCING MICROORGANISMS, FATTY ACID COMPOSITIONS, AND METHODS OF MAKING AND USES THEREOF
    Publication number: 20160374976
    Abstract: The invention is directed to microbial oils containing omega-3 polyunsaturated fatty acids comprising docosahexaenoic acid, eicosapentaenoic acid, and optionally docosapentaenoic acid and dosage forms containing such oils.
    Type: Application
    Filed: June 30, 2016
    Publication date: December 29, 2016
    Inventors: Kirk E. APT, Paul Warren BEHRENS, Jon Milton HANSEN, Joseph W. PFEIFER, III, Tracey Lynn STAHL, Ross ZIRKLE
  • Polypeptide for improving protein production in microorganisms of the phylum Labyrinthulomycota
    Patent number: 9518102
    Abstract: The present invention relates to recombinant cells and microorganisms of the phylum Labyrinthulomycota and their use in heterologous protein production. Novel promoter, terminator, and signal sequences for efficient production and, optionally, secretion of polypeptides from recombinant host cells and microorganisms are also encompassed by the present invention.
    Type: Grant
    Filed: November 19, 2014
    Date of Patent: December 13, 2016
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, James Casey Lippmeier, David Simpson, Jun Wang, James P. Wynn, Ross Zirkle
  • BIOLOGICAL OILS AND PRODUCTION AND USES THEREOF
    Publication number: 20160355851
    Abstract: The present invention provides biological oils and methods and uses thereof. The biological oils are preferably produced by heterotrophic fermentation of one or more microorganisms using cellulose-containing feedstock as a main source of carbon. The present invention also provides methods of producing lipid-based biofuels and food, nutritional, and pharmaceutical products using the biological oils.
    Type: Application
    Filed: August 16, 2016
    Publication date: December 8, 2016
    Inventors: James Casey LIPPMEIER, Joseph W. PFEIFER, III, Jon Milton HANSEN, III, Kirk E. APT, William Robert BARCLAY, Paul Warren BEHRENS, David Christian MARTIN
  • THRAUSTOCHYTRIDS, FATTY ACID COMPOSITIONS, AND METHODS OF MAKING AND USES THEREOF
    Publication number: 20160309748
    Abstract: The present invention is directed to isolated thraustochytrid microorganisms as well as strains and mutants thereof. The invention is further directed to biomasses, microbial oils, compositions, cultures, methods of producing microbial oils, and methods of using the isolated thraustochytrids, biomasses, and microbial oils.
    Type: Application
    Filed: July 13, 2016
    Publication date: October 27, 2016
    Inventors: Kirk E. APT, Joseph W. PFEIFER, III, Jon Milton Hansen, Paul Warren BEHRENS, Ross ZIRKLE, Tracey Lynn STAHL
  • Biological oils and production and uses thereof
    Patent number: 9453172
    Abstract: The present invention provides biological oils and methods and uses thereof. The biological oils are preferably produced by heterotrophic fermentation of one or more microorganisms using cellulose-containing feedstock as a main source of carbon. The present invention also provides methods of producing lipid-based biofuels and food, nutritional, and pharmaceutical products using the biological oils.
    Type: Grant
    Filed: February 21, 2012
    Date of Patent: September 27, 2016
    Assignee: DSM IP Assets B.V.
    Inventors: James Casey Lippmeier, Joseph W. Pfeifer, III, Jon Milton Hansen, Kirk E. Apt, William Robert Barclay, Paul Warren Behrens, David Christian Martin
  • Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
    Patent number: 9414612
    Abstract: The present invention is directed to isolated thraustochytrid microorganisms as well as strains and mutants thereof. The invention is further directed to biomasses, microbial oils, compositions, cultures, methods of producing microbial oils, and methods of using the isolated thraustochytrids, biomasses, and microbial oils.
    Type: Grant
    Filed: August 29, 2011
    Date of Patent: August 16, 2016
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, Joseph W. Pfeifer, III, Jon Milton Hansen, Paul Warren Behrens, Ross Zirkle, Tracey Lynn Stahl
  • Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
    Patent number: 9222112
    Abstract: The invention is directed to microbial oils containing omega-3 polyunsaturated fatty acids comprising docosahexaenoic acid, eicosapentaenoic acid, and optionally docosapentaenoic acid and dosage forms containing such oils.
    Type: Grant
    Filed: July 20, 2012
    Date of Patent: December 29, 2015
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, Paul Warren Behrens, Jon Milton Hansen, Joseph W. Pfeifer, III, Tracey Lynn Stahl, Ross Zirkle
  • EICOSAPENTAENOIC ACID-PRODUCING MICROORGANISMS, FATTY ACID COMPOSITIONS, AND METHODS OF MAKING AND USES THEREOF
    Publication number: 20150313861
    Abstract: The present invention is directed to isolated microorganisms as well as strains and mutants thereof, biomasses, microbial oils, compositions, and cultures; methods of producing the microbial oils, biomasses, and mutants; and methods of using the isolated microorganisms, biomasses, and microbial oils.
    Type: Application
    Filed: May 12, 2015
    Publication date: November 5, 2015
    Inventors: Kirk E. APT, Paul Warren BEHRENS, Jon Milton HANSEN, Joseph W. PFEIFER, III, Tracey Lynn STAHL, Ross ZIRKLE
  • EICOSAPENTAENOIC ACID-PRODUCING MICROORGANISMS, FATTY ACID COMPOSITIONS, AND METHODS OF MAKING AND USES THEREOF
    Publication number: 20150275244
    Abstract: The invention is directed to microbial oils containing omega-3 polyunsaturated fatty acids comprising docosahexaenoic acid, eicosapentaenoic acid, and optionally docosapentaenoic acid and dosage forms containing such oils.
    Type: Application
    Filed: April 28, 2015
    Publication date: October 1, 2015
    Inventors: Kirk E. APT, Paul Warren BEHRENS, Jon Milton HANSEN, Joseph W. PFEIFER, III, Tracey Lynn STAHL, Ross ZIRKLE
  • EICOSAPENTAENOIC ACID-PRODUCING MICROORGANISMS, FATTY ACID COMPOSITIONS, AND METHODS OF MAKING AND USES THEREOF
    Publication number: 20150237888
    Abstract: The present invention is directed to isolated microorganisms as well as strains and mutants thereof, biomasses, microbial oils, compositions, and cultures; methods of producing the microbial oils, biomasses, and mutants; and methods of using the isolated microorganisms, biomasses, and microbial oils.
    Type: Application
    Filed: May 12, 2015
    Publication date: August 27, 2015
    Inventors: Kirk E. APT, Paul Warren BEHRENS, Jon Milton HANSEN, Joseph W. PFEIFER, III, Tracey Lynn STAHL, Ross ZIRKLE
  • EICOSAPENTAENOIC ACID-PRODUCING MICROORGANISMS, FATTY ACID COMPOSITIONS, AND METHODS OF MAKING AND USES THEREOF
    Publication number: 20150223492
    Abstract: The present invention is directed to isolated microorganisms as well as strains and mutants thereof, biomasses, microbial oils, compositions, and cultures; methods of producing the microbial oils, biomasses, and mutants; and methods of using the isolated microorganisms, biomasses, and microbial oils.
    Type: Application
    Filed: April 28, 2015
    Publication date: August 13, 2015
    Inventors: Joseph W. PFEIFER, III, Jon Milton HANSEN, Jose R. GARCIA, Xiao Daniel DONG, Paul Warren BEHRENS, Kirk E. APT
  • POLYUNSATURATED FATTY ACID SYNTHASE NUCLEIC ACID MOLECULES AND POLYPEPTIDES, COMPOSITIONS, AND METHODS OF MAKING AND USES THEREOF
    Publication number: 20150152450
    Abstract: The present invention is directed to isolated nucleic acid molecules and polypeptides of thraustochytrid polyunsaturated fatty acid (PUFA) synthases involved in the production of PUFAs, including PUFAs enriched in docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), or a combination thereof. The present invention is directed to vectors and host cells comprising the nucleic acid molecules, polypeptides encoded by the nucleic acid molecules, compositions comprising the nucleic acid molecules or polypeptides, and methods of making and uses thereof.
    Type: Application
    Filed: December 10, 2014
    Publication date: June 4, 2015
    Inventors: Kirk E. APT, Leslie RICHTER, David SIMPSON, Ross ZIRKLE
  • Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
    Patent number: 9045785
    Abstract: The present invention is directed to isolated microorganisms as well as strains and mutants thereof, biomasses, microbial oils, compositions, and cultures; methods of producing the microbial oils, biomasses, and mutants; and methods of using the isolated microorganisms, biomasses, and microbial oils.
    Type: Grant
    Filed: July 20, 2012
    Date of Patent: June 2, 2015
    Assignee: DSM IP Assets B.V.
    Inventors: Joseph W. Pfeifer, III, Jon Milton Hansen, Jose R. Garcia, Xiao Daniel Dong, Paul Warren Behrens, Kirk E. Apt
  • POLYPEPTIDE FOR IMPROVING PROTEIN PRODUCTION IN MICROORGANISMS OF THE PHYLUM LABYRINTHULOMYCOTA
    Publication number: 20150132803
    Abstract: The present invention relates to recombinant cells and microorganisms of the phylum Labyrinthulomycota and their use in heterologous protein production. Novel promoter, terminator, and signal sequences for efficient production and, optionally, secretion of polypeptides from recombinant host cells and microorganisms are also encompassed by the present invention.
    Type: Application
    Filed: November 19, 2014
    Publication date: May 14, 2015
    Inventors: Kirk E. APT, James Casey LIPPMEIER, David SIMPSON, Jun WANG, James P. WYNN, Ross ZIRKLE
  • Polynucleotide for improving protein production in microorganisms of the phylum labyrinthulomycota
    Patent number: 9012616
    Abstract: The present invention relates to recombinant cells and microorganisms of the phylum Labyrinthulomycota and their use in heterologous protein production. Novel promoter, terminator, and signal sequences for efficient production and, optionally, secretion of polypeptides from recombinant host cells and microorganisms are also encompassed by the present invention.
    Type: Grant
    Filed: December 17, 2013
    Date of Patent: April 21, 2015
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, James Casey Lippmeier, David Simpson, Jun Wang, James P. Wynn, Ross Zirkle
  • EICOSAPENTAENOIC ACID-PRODUCING MICROORGANISMS, FATTY ACID COMPOSITIONS, AND METHODS OF MAKING AND USES THEREOF
    Publication number: 20150094382
    Abstract: The present invention is directed to isolated microorganisms as well as strains and mutants thereof, biomasses, microbial oils, compositions, and cultures; methods of producing the microbial oils, biomasses, and mutants; and methods of using the isolated microorganisms, biomasses, and microbial oils.
    Type: Application
    Filed: December 10, 2014
    Publication date: April 2, 2015
    Inventors: Joseph W. PFEIFER, III, Jon Milton HANSEN, Jose R. GARCIA, Xiao Daniel DONG, Paul Warren BEHRENS, Kirk E. APT
  • Polyunsaturated fatty acid synthase nucleic acid molecules and polypeptides, compositions, and methods of making and uses thereof
    Patent number: 8940884
    Abstract: The present invention is directed to isolated nucleic acid molecules and polypeptides of thraustochytrid polyunsaturated fatty acid (PUFA) synthases involved in the production of PUFAs, including PUFAs enriched in docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), or a combination thereof. The present invention is directed to vectors and host cells comprising the nucleic acid molecules, polypeptides encoded by the nucleic acid molecules, compositions comprising the nucleic acid molecules or polypeptides, and methods of making and uses thereof.
    Type: Grant
    Filed: March 19, 2010
    Date of Patent: January 27, 2015
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, Leslie Richter, David Simpson, Ross Zirkle
  • YEAST STRAINS AND THEIR USES IN THE PRODUCTION OF LIPIDS
    Publication number: 20140199755
    Abstract: The invention is directed to isolated microorganisms, as well as biomasses, cultures, microbial oils, and compositions thereof. The invention also provides methods of producing the microbial oils and methods of using the isolated microorganisms, biomasses, and microbial oils.
    Type: Application
    Filed: February 21, 2014
    Publication date: July 17, 2014
    Applicant: DSM IP ASSETS B.V.
    Inventors: Kirk E. APT, William R. BARCLAY, Paul Warren BEHRENS
  • Yeast strains and their uses in the production of lipids
    Patent number: 8735109
    Abstract: The invention is directed to isolated microorganisms, as well as biomasses, cultures, microbial oils, and compositions thereof. The invention also provides methods of producing the microbial oils and methods of using the isolated microorganisms, biomasses, and microbial oils.
    Type: Grant
    Filed: March 11, 2011
    Date of Patent: May 27, 2014
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, William R. Barclay, Paul Warren Behrens
  • PROTEIN PRODUCTION IN MICROORGANISMS OF THE PHYLUM LABYRINTHULOMYCOTA
    Publication number: 20140106402
    Abstract: The present invention relates to recombinant cells and microorganisms of the phylum Labyrinthulomycota and their use in heterologous protein production. Novel promoter, terminator, and signal sequences for efficient production and, optionally, secretion of polypeptides from recombinant host cells and microorganisms are also encompassed by the present invention.
    Type: Application
    Filed: December 17, 2013
    Publication date: April 17, 2014
    Applicant: DSM IP Assets B.V.
    Inventors: Kirk E. APT, James Casey LIPPMEIER, David SIMPSON, Jun WANG, James P. WYNN, Ross ZIRKLE