Patents by Inventor Kirk E. Apt

Kirk E. Apt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protein production in microorganisms of the phylum labyrinthulomycota
    Patent number: 8637651
    Abstract: The present invention relates to recombinant cells and microorganisms of the phylum Labyrinthulomycota and their use in heterologous protein production. Novel promoter, terminator, and signal sequences for efficient production and, optionally, secretion of polypeptides from recombinant host cells and microorganisms are also encompassed by the present invention.
    Type: Grant
    Filed: March 15, 2010
    Date of Patent: January 28, 2014
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, James Casey Lippmeier, David Simpson, Jun Wang, James P. Wynn, Ross Zirkle
  • Yeast strains and their uses in the production of lipids
    Patent number: 8529886
    Abstract: The invention is directed to isolated microorganisms, as well as biomasses, cultures, microbial oils, and compositions thereof. The invention also provides methods of producing the microbial oils and methods of using the isolated microorganisms, biomasses, and microbial oils.
    Type: Grant
    Filed: March 11, 2011
    Date of Patent: September 10, 2013
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, William R. Barclay, Paul Warren Behrens
  • EICOSAPENTAENOIC ACID-PRODUCING MICROORGANISMS, FATTY ACID COMPOSITIONS, AND METHODS OF MAKING AND USES THEREOF
    Publication number: 20130190520
    Abstract: The invention is directed to microbial oils containing omega-3 polyunsaturated fatty acids comprising docosahexaenoic acid, eicosapentaenoic acid, and optionally docosapentaenoic acid and dosage forms containing such oils.
    Type: Application
    Filed: July 20, 2012
    Publication date: July 25, 2013
    Inventors: Kirk E. APT, Paul Warren Behrens, Jon Milton Hansen, Joseph W. Pfeifer, III, Tracey Lynn Stahl, Ross Zirkle
  • EICOSAPENTAENOIC ACID-PRODUCING MICROORGANISMS, FATTY ACID COMPOSITIONS, AND METHODS OF MAKING AND USES THEREOF
    Publication number: 20130172590
    Abstract: The present invention is directed to isolated microorganisms as well as strains and mutants thereof, biomasses, microbial oils, compositions, and cultures; methods of producing the microbial oils, biomasses, and mutants; and methods of using the isolated microorganisms, biomasses, and microbial oils.
    Type: Application
    Filed: July 20, 2012
    Publication date: July 4, 2013
    Inventors: Joseph W. PFEIFER III, Jon Milton Hansen, Jose R. Garcia, Xiao Daniel Dong, Paul Warren Behrens, Kirk E. Apt
  • YEAST STRAINS AND THEIR USES IN THE PRODUCTION OF LIPIDS
    Publication number: 20130122557
    Abstract: The invention is directed to isolated microorganisms, as well as biomasses, cultures, microbial oils, and compositions thereof. The invention also provides methods of producing the microbial oils and methods of using the isolated microorganisms, biomasses, and microbial oils.
    Type: Application
    Filed: March 11, 2011
    Publication date: May 16, 2013
    Inventors: Kirk E. Apt, William R. Barclay, Paul Warren Behrens
  • Methods, Biological Oils, Biofuels, Units, and Organisms Related to Use in Compression Engines
    Publication number: 20120323029
    Abstract: Methods, biological oils, biofuels, units, and/or organisms directed to use in compression engines. A method of producing biological oils includes producing an organism and having the organism consume a feedstock. The organism includes a lipid containing fatty acids. The organism meets or exceeds at least two metrics. The metrics include: A) a cell density of at least about 115 grams per liter; B) a fatty acid content of at least about 49 percent on a dry mass basis; C) a fatty acid productivity of at least about 15 grams per liter per day; D) a fatty acid yield of at least about 0.175 grams of fatty acids produced per grams of the feedstock consumed; E) a 24 hour peak fatty acid productivity of at least about 30 grams per liter per day; F) an extraction efficiency on a percent of total fatty acid content basis of at least about 50 percent; and/or G) yield of fatty acids on oxygen of more than about 0.4 as grams of fatty acids produced per gram of oxygen consumed basis.
    Type: Application
    Filed: March 8, 2011
    Publication date: December 20, 2012
    Applicant: BP Biofuels IK Limited
    Inventors: Joseph W. Pfeifer, III, Paul W. Behrens, Michael A. Johnson, Jon M. Hansen, Kirk E. Apt, William R. Barclay, David Christian Martin, Jacob Borden
  • Biological Oils and Production and Uses Thereof
    Publication number: 20120272566
    Abstract: The present invention provides biological oils and methods and uses thereof. The biological oils are preferably produced by heterotrophic fermentation of one or more microorganisms using cellulose-containing feedstock as a main source of carbon. The present invention also provides methods of producing lipid-based biofuels and food, nutritional, and pharmaceutical products using the biological oils.
    Type: Application
    Filed: February 21, 2012
    Publication date: November 1, 2012
    Inventors: James Casey LIPPMEIER, Joseph W. Pfeifer, III, Jon Milton Hansen, Kirk E. Apt, William Robert Barclay, Paul Warren Behrens, David Christian Martin
  • Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
    Patent number: 8207363
    Abstract: The present invention is directed to isolated thraustochytrid microorganisms as well as strains and mutants thereof. The invention is further directed to biomasses, microbial oils, compositions, cultures, methods of producing microbial oils, and methods of using the isolated thraustochytrids, biomasses, and microbial oils.
    Type: Grant
    Filed: March 19, 2009
    Date of Patent: June 26, 2012
    Assignee: Martek Biosciences Corporation
    Inventors: Kirk E. Apt, Joseph W. Pfeifer, III, Jon Milton Hansen, Paul Warren Behrens, Ross Zirkle, Tracey Lynn Stahl
  • Thraustochytrids, Fatty Acid Compositions, and Methods of Making and Uses Thereof
    Publication number: 20120088831
    Abstract: The present invention is directed to isolated thraustochytrid microorganisms as well as strains and mutants thereof. The invention is further directed to biomasses, microbial oils, compositions, cultures, methods of producing microbial oils, and methods of using the isolated thraustochytrids, biomasses, and microbial oils.
    Type: Application
    Filed: August 29, 2011
    Publication date: April 12, 2012
    Inventors: Kirk E. APT, Joseph W. Pfeifer, III, Jon Milton Hansen, Paul Warren Behrens, Ross Zirkle, Tracey Lynn Stahl
  • YEAST STRAINS AND THEIR USES IN THE PRODUCTION OF LIPIDS
    Publication number: 20120034190
    Abstract: The invention is directed to isolated microorganisms, as well as biomasses, cultures, microbial oils, and compositions thereof. The invention also provides methods of producing the microbial oils and methods of using the isolated microorganisms, biomasses, and microbial oils.
    Type: Application
    Filed: March 11, 2011
    Publication date: February 9, 2012
    Inventors: Kirk E. APT, William R. BARCLAY, Paul Warren BEHRENS
  • Extraction of Lipid From Cells and Products Therefrom
    Publication number: 20110295028
    Abstract: The present invention relates to processes for obtaining a lipid from a cell by lysing the cell, contacting the cell with a base and/or salt, and separating the lipid. The present invention is also directed to a lipid prepared by the processes of the present invention. The present invention is also directed to microbial lipids having a particular anisidine value, peroxide value, and/or phosphorus content.
    Type: Application
    Filed: June 1, 2011
    Publication date: December 1, 2011
    Inventors: Stephen Robert Cherinko, Robert Cody Kertis, Kirk E. Apt, Paul Warren Behrens, Jon Milton Hansen, Joseph W. Pfeifer, III, Tracey Lynn Stahl, Ross Zirkle, Nasrin Tabayeh Burke, Krishna Raman, Neil Francis Leininger
  • Eicosapentaenoic Acid-Producing Microorganisms, Fatty Acid Compositions, and Methods of Making and Uses Thereof
    Publication number: 20110177031
    Abstract: The present invention is directed to isolated microorganisms as well as strains and mutants thereof, biomasses, microbial oils, compositions, and cultures; methods of producing the microbial oils, biomasses, and mutants; and methods of using the isolated microorganisms, biomasses, and microbial oils.
    Type: Application
    Filed: March 22, 2010
    Publication date: July 21, 2011
    Inventors: KIRK E. APT, PAUL WARREN BEHRENS, JON MILTON HANSEN, JOSEPH W. PFEIFER, III, TRACEY LYNN STAHL, ROSS ZIRKLE
  • Polyunsaturated Fatty Acid Synthase Nucleic Acid Molecules and Polypeptides, Compositions, and Methods of Making and Uses Thereof
    Publication number: 20100266564
    Abstract: The present invention is directed to isolated nucleic acid molecules and polypeptides of thraustochytrid polyunsaturated fatty acid (PUFA) synthases involved in the production of PUFAs, including PUFAs enriched in docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), or a combination thereof. The present invention is directed to vectors and host cells comprising the nucleic acid molecules, polypeptides encoded by the nucleic acid molecules, compositions comprising the nucleic acid molecules or polypeptides, and methods of making and uses thereof.
    Type: Application
    Filed: March 19, 2010
    Publication date: October 21, 2010
    Inventors: Kirk E. Apt, Leslie Richter, David Simpson, Ross Zirkle
  • Thraustochytrids, Fatty Acid Compositions, and Methods of Making and Uses Thereof
    Publication number: 20100239533
    Abstract: The present invention is directed to isolated thraustochytrid microorganisms as well as strains and mutants thereof. The invention is further directed to biomasses, microbial oils, compositions, cultures, methods of producing microbial oils, and methods of using the isolated thraustochytrids, biomasses, and microbial oils.
    Type: Application
    Filed: March 19, 2009
    Publication date: September 23, 2010
    Applicant: Martek Biosciences Corporation
    Inventors: Kirk E. APT, Joseph W. Pfeifer, III, Jon Milton Hansen, Paul Warren Behrens, Ross Zirkle, Tracey Lynn Stahl
  • Protein Production in Microorganisms of the Phylum Labyrinthulomycota
    Publication number: 20100233760
    Abstract: The present invention relates to recombinant cells and microorganisms of the phylum Labyrinthulomycota and their use in heterologous protein production. Novel promoter, terminator, and signal sequences for efficient production and, optionally, secretion of polypeptides from recombinant host cells and microorganisms are also encompassed by the present invention.
    Type: Application
    Filed: March 15, 2010
    Publication date: September 16, 2010
    Inventors: Kirk E. Apt, James Casey Lippmeier, David Simpson, Jun Wang, James P. Wynn, Ross Zirkle
  • Biological oils and production and uses Thereof
    Publication number: 20090064567
    Abstract: The present invention provides biological oils and methods and uses thereof. The biological oils are preferably produced by heterotrophic fermentation of one or more microorganisms using cellulose-containing feedstock as a main source of carbon. The present invention also provides methods of producing lipid-based biofuels and food, nutritional, and pharmaceutical products using the biological oils.
    Type: Application
    Filed: September 8, 2008
    Publication date: March 12, 2009
    Inventors: James Casey Lippmeier, Joseph W. Pfeifer, III, Jon Milton Hansen, Kirk E. Apt, William Robert Barclay, Paul Warren Behrens, David Christian Martin